Session Details
[GS02]Challenges of Young Researchers in Establishing Breakthrough Therapies for Inflammatory Diseases
Sat. Mar 29, 2025 10:15 AM - 11:45 AM JST
Sat. Mar 29, 2025 1:15 AM - 2:45 AM UTC
Sat. Mar 29, 2025 1:15 AM - 2:45 AM UTC
Room 3 (Fukuoka International Congress Center: 502+503 [5F])
Organizer: Yohei Takenaka (Grad. Sch. of Pharm. Sci., Tokyo Univ. Sci.), Hayato Shimora (Fac. of Pharm. Sci., Setsunan Univ.)
Inflammation is originally important for the maintenance of homeostasis in the body. On the other hand, the control of excessive, acute or chronic inflammation, which is responsible for the pathogenesis and exacerbation of various diseases, has been considered a therapeutic target for many diseases. However, there are still several inflammatory diseases that have not been sufficiently treated with conventional therapeutic strategies. Recent remarkable advancement in scientific technology have brought about a paradigm shift in the treatment of many diseases, but there are also some issues of concern such as rising medical costs. In order to maximize the use of increasingly sophisticated scientific technology, it is necessary to cause "chemical reactions" between the various specializations, thereby leading to the efficient establishment of innovative treatments for intractable inflammatory diseases.
In this symposium, we will introduce studies that aim to establish new treatments for inflammatory diseases from a variety of approaches, including immunology, pharmacology, molecular biology, and pharmaceutics. We hope that this symposium will provide an opportunity for young researchers with diverse backgrounds to actively exchange opinions, which will help them to develop into researchers who can contribute to the construction of innovative treatments for inflammatory diseases.
In this symposium, we will introduce studies that aim to establish new treatments for inflammatory diseases from a variety of approaches, including immunology, pharmacology, molecular biology, and pharmaceutics. We hope that this symposium will provide an opportunity for young researchers with diverse backgrounds to actively exchange opinions, which will help them to develop into researchers who can contribute to the construction of innovative treatments for inflammatory diseases.
オーガナイザー挨拶：竹中 洋平（東京理大院薬）
[GS02-1]Acquisition of steroid resistance in type 2 innate lymphoid cells via JAK-STAT-Bcl-xL pathway in asthma
○Hayato Shimora1, Yukiko Nakayama1, Ryunosuke Tanioka1, Hiroto Maeyama1, Masaya Matsuda1, Takeshi Nabe1 (1. Lab. of Immunopharmacol., Fac. of Pharm. Sci., Setsunan Univ.)
[GS02-2]Elucidation of the differentiation mechanism of fibrosis-promoting macrophages in metabolic dysfunction-associated steatohepatitis (MASH).
○Ayaka Iwata1, Natsuki Shibata1, Kenichi Asano1,2, Masato Tanaka1 (1. Grad school of Life Sci, Tokyo Univ Pharm Life Sci, 2. School of Med, Yokohama City Univ)
[GS02-3]The role of immune escape mechanisms of senescent cells in orchestrating skin pathology in lupus erythematosus
○Sena Yamamoto1, Yuki Saito2, Seina Nakano1, Tsukasa Sato1, Norihiro Miura1, Kentaro Nagaoka2, Arisa Kita2, Maki Miyajima1, Shogo Ijima2, Koji Taniguchi3, Atsushi Niida4, Takako S. Chikenji1 (1. Dept. of Health Sci. and Grad. Sch. of Health Sci., Hokkaido Univ., 2. Sapporo Med. Univ. Sch. of Med., 3. Fac. of Med. and Grad. Sch. of Med., Hokkaido Univ., 4. Ins. of Med. Sci., Tokyo Univ.)
[GS02-4]Silk elastin-like protein permits macrophages to induce anti-inflammatory polarization
○Taichi Washisaka1, Tomo Unzai2, Yasuhiko Tabata2 (1. Inst. Life. Med., Kyoto Univ., 2. Grad. Sch. Med., Kyoto Univ.)
[GS02-5]Effect of antidepressants and antimalarials on cytokine production via TLRs recognizing pathogen nucleic acids and their application as treatment for sepsis
○Yohei Takenaka1, Mitsutoshi Tsukimoto1 (1. Grad. Sch. of Pharm. Sci., Tokyo Univ. Sci.)