Session Details
[29-13-pm]Drug Discovery, SAR 3
Sat. Mar 29, 2025 3:10 PM - 4:10 PM JST
Sat. Mar 29, 2025 6:10 AM - 7:10 AM UTC
Sat. Mar 29, 2025 6:10 AM - 7:10 AM UTC
Room 13 (Fukuoka International Congress Center: 402+403 [4F])
Chair: Baba Yoshiyasu, Toru Komatsu
[29-13-pm08S]Synthesis of Improved G4 Ligands by TriQuinoline (TQ) Derivatives with Cationic Substituents
○Taiga Karimata1, Yohko Yamazaki2, Wei Xu1, Naoya Kumagai1,2 (1. Grad. Sch. Pharm. Sci., Keio Univ., 2. Institute of Microbial Chemistry)
[29-13-pm09]Synthetic studies on Trisubstituted Oxazoles by [2+2+1] Annulation and Application to PPAR ligands
○Hiroaki Ishida1, Yuma Iwamoto1, Shoya Homma1, Toshimasa Itoh1 (1. Showa Pharmaceutical University)
[29-13-pm10S]2-(3',4'-Dihydroxybenzyl)-1,2,3,4-tetrahydronaphthalene, designed from natural homoisoflavan, is a strong AChE inhibitor and a remarkable promoter of neurite outgrowth
○Ayaka Saiki1, Takeru Koga2, Aya Ogata1, Akihiro Tai2, Toshiro Noshita1 (1. Gifu Univ. Med. Sci., 2. Tokusima University Graduate School of Technology, Industrial and Social Sciences)
[29-13-pm11S]Discovery of novel class IIa HDAC inhibitors through evaluation based on enzyme inhibition kinetics
○Rio Furutani1, Yukihiro Itoh1, Yasynobu Yamashita1, Yuri Takada1, Takayoshi Suzuki1 (1. SANKEN, Osaka Univ.)
[29-13-pm12S]Development of Novel Retinoids with Selective CRABP1-Mediated Non-Genomic Activity
○Xiaoyue Guo1, Yue Ma2, Yuuki Hosaka1, Michiko Nakaishi2, Li-Na Wei3, Hiroyuki Kagechika1 (1. Laboratory for Biomaterials and Bioengineering, Institute of Integrated Research, Institute of Science Tokyo, 2. Research Infrastructure Management Center, Institute of Science Tokyo, 3. Department of Pharmacology, University of Minnesota)