Session Details
[1S07e]New insights into prediction mechanisms of the hippocampus and basal ganglia
Tue. Mar 10, 2026 4:40 PM - 6:30 PM JST
Tue. Mar 10, 2026 7:40 AM - 9:30 AM UTC
Tue. Mar 10, 2026 7:40 AM - 9:30 AM UTC
Room 7(School of Nursing Building, 1F, 102)
Organizers/Chairs: Yoshikazu Isomura (Institute of Science Tokyo), Masaaki Ogawa (Shiga University of Medical Science)
Co-hosted by: KAKENHI Transformative Research Areas (A) "Adaptive Circuit Census"
This symposium highlights emerging research that revises traditional views on the brain's predictive mechanisms essential for survival. The hippocampus, known for episodic memory-based prediction and replay, produces sharp-wave ripples. The basal ganglia support reinforcement learning via dopamine-based reward prediction errors. Tsutsui-Kimura expands basal ganglia prediction mechanisms beyond reward. Ogawa reveals dual-polarity of prediction errors in the basal ganglia and explores hippocampal roles. Rios revisits the functional significance of hippocampal ripples in relation to the reward system. Yanagisawa links hippocampal ripples to spontaneous thoughts using human intracranial EEG. The symposium will share these advances and deepen our understanding of neural prediction mechanisms.
Introduction
[1S07e-01]Dopamine modulates competing-valence based learning
*Iku Tsutsui-Kimura1 (1. Hokkaido Univ.)
[1S07e-02]Neural mechanisms for persistent goal pursuit: role of prediction updating in the hippocampus and nucleus accumbens
*Masaaki Ogawa1 (1. Shiga University of Medical Science)
[1S07e-03]Modulation of hippocampal ripples by reward behavior under head fixed conditions
*ALAIN RIOS1 (1. Institute of Science Tokyo)
[1S07e-04]Hippocampal sharp-wave ripples and self-generated thoughts in humans
*Takufumi Yanagisawa1,2 (1. Department of Neuroinformatics, The University of Osaka Graduate School of Medicine, 2. Department of Neurosurgery, The University of Osaka Graduate School of Medicine)