講演情報
[1B12]Catalytic conversion of acetal-protected 2,5-diformylfuran to 2,5-bis(aminomethyl)tetrahydrofuran via reductive amination and subsequent hydrogenation of furan ring
○Nirupama Sheet1, Ryota Osuga1, Satoshi Suganuma1, Takato Mitsudome2, Kiyotaka Nakajima1 (1. Institute for Catalysis, Hokkaido University, 2. Department of Materials Engineering Science, Graduate School of Engineering Science, Osaka University)
キーワード：
Biomass conversion、Reductive amination、Hydrogenation、Co2P nanorod catalyst、Rh/HT catalyst
We have designed a stepwise synthesis of 2,5-bis(aminomethyl)tetrahydrofuran (BAMTHF) by reductive amination of biomass-derived mono-acetalized 2,5-diformylfuran (DFF) using Co2P nanorod (NR) catalyst and its subsequent hydrogenation with hydrotalcite (HT) supported Rh catalyst. BAMTHF is a valuable intermediate in the synthesis of epoxy resins, pharmaceuticals, nylon 66-type polymers and so on. Consecutive amination of the free formyl group and the six-membered ring acetal in DFF with Co2P NR gave 2,5-bis(aminomethyl)furan (BAMF) in a high yield (>90%). The ring hydrogenation of BAMF with Rh/HT affords BAMTHF in 85% yield at room temperature under 0.5 MPa H2 pressure.