[1S03a] 難治性不整脈および心筋症の病態解析に基づく個別化治療戦略の構築に向けて

15:00 〜 15:20

[1S03a-02] KCND3 variants as a Cause of Early Repolarization and Epilepsy: Mechanistic Elucidation and Drug Repositioning

*Tserenlkham Byambajav^1,2, Takeru Makiyama³, Koichiro Takayama¹, Hai Huang³, Minoru Horie⁴, Seiko Ohno¹ (1. Medical Genome Center, National Cerebral and Cardiovascular Center, Japan, 2. Laboratory of Epidemiology and Prevention, Kobe Pharmaceutical University, Japan, 3. Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto University, Japan, 4. Department of Cardiovascular Medicine, Shiga University of Medical Science, Japan)

キーワード：

Early Repolarization Syndrome、KCND3、voltage-gated potassium channel、inherited arrhythmia、personalized therapy

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