[[A]A303-1pm] 17. Biofunctional Chemistry, Biotechnology

1:00 PM - 1:20 PM JST(4:00 AM - 4:20 AM UTC)Japanese

[[A]A303-1pm-01] Internal cap-initiated translation provides efficient protein production from circular mRNA

○Yuko Nakashima¹, Kosuke Fukuchi¹, Naoko Abe¹, Seigo Kimura³, Fumitaka Hashiya⁴, Yuichi Shichino⁵, Yiwei Liu¹, Ryoko Ogisu¹, Satomi Sugiyama¹, Daisuke Kawaguchi¹, Masahito Inagaki¹, Zheyu Meng¹, Shiryu Kajihara¹, Mizuki Tada¹, Satoshi Uchida^6,7, Ting-Ting Li¹, Ramkrishna Maity¹, Tairin Kawasaki¹, Yasuaki Kimura¹, Shintaro Iwasaki^5,8, Hiroshi Abe^1,2 (1. Department of Chemistry, Graduate School of Science, Nagoya University, 2. iGCORE, 3. Integrated Research Consortium on Chemical Sciences (IRCCS), Nagoya University, 4. Research Center for Materials Science, Nagoya University, 5. RIKEN Cluster for Pioneering Research, 6. Medical Research Institute, Tokyo Medical and Dental University (TMDU), 7. Innovation Center of NanoMedicine (iCONM), Kawasaki Institute of Industrial Promotion, 8. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo)

Keywords:

Circular mRNA,Cap structure,Translational activity