[[A]A303-1pm] 17. Biofunctional Chemistry, Biotechnology | The 105th CSJ Annual Meeting

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Academic Program [Oral B]17. Biofunctional Chemistry, Biotechnology : Oral B

[[A]A303-1pm]17. Biofunctional Chemistry, Biotechnology

Wed. Mar 26, 2025 1:00 PM - 2:50 PM JST
Wed. Mar 26, 2025 4:00 AM - 5:50 AM UTC

[A]A303(A303, Bldg. 1, Area 3 [3F])

1:00 PM - 1:20 PM JST(4:00 AM - 4:20 AM UTC)Japanese

[[A]A303-1pm-01]Internal cap-initiated translation provides efficient protein production from circular mRNA

○Yuko Nakashima¹, Kosuke Fukuchi¹, Naoko Abe¹, Seigo Kimura³, Fumitaka Hashiya⁴, Yuichi Shichino⁵, Yiwei Liu¹, Ryoko Ogisu¹, Satomi Sugiyama¹, Daisuke Kawaguchi¹, Masahito Inagaki¹, Zheyu Meng¹, Shiryu Kajihara¹, Mizuki Tada¹, Satoshi Uchida^6,7, Ting-Ting Li¹, Ramkrishna Maity¹, Tairin Kawasaki¹, Yasuaki Kimura¹, Shintaro Iwasaki^5,8, Hiroshi Abe^1,2 (1. Department of Chemistry, Graduate School of Science, Nagoya University, 2. iGCORE, 3. Integrated Research Consortium on Chemical Sciences (IRCCS), Nagoya University, 4. Research Center for Materials Science, Nagoya University, 5. RIKEN Cluster for Pioneering Research, 6. Medical Research Institute, Tokyo Medical and Dental University (TMDU), 7. Innovation Center of NanoMedicine (iCONM), Kawasaki Institute of Industrial Promotion, 8. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo)

1:20 PM - 1:40 PM JST(4:20 AM - 4:40 AM UTC)Japanese

[[A]A303-1pm-02]Development of efficient purification methods for circular mRNA

○Shiryu Kajihara¹, Naoko Abe¹, Yuko Nakashima¹, Kosuke Fukuchi¹, Fumitaka Hashiya², Hiroshi Abe^1,3 (1. Department of Chemistry, Graduate School of Science, Nagoya University, 2. Research Center for Materials Science, Nagoya University, 3. Institute for Glyco-core Research (iGCORE), Nagoya University)

1:40 PM - 2:00 PM JST(4:40 AM - 5:00 AM UTC)Japanese

[[A]A303-1pm-03]Development of Chemically Modified mRNA based on Chemical Synthesis for Highly Efficacious mRNA Therapeutics

○Yasuaki Kimura¹, Hiroto Iwai², Masakazu Honma², Hiroki Yamada², Kosuke Nakamoto¹, Masahito Inagaki¹, Fumitaka Hashiya¹, Naoko Abe¹, Junichiro Yamamoto², Hiroshi Abe^1,3 (1. Nagoya Univeristy, 2. Kyowa Kirin Co., Ltd., 3. Institute for Glyco-core Research)

2:00 PM - 2:10 PM JST(5:00 AM - 5:10 AM UTC)

Break

2:10 PM - 2:30 PM JST(5:10 AM - 5:30 AM UTC)English

[[A]A303-1pm-04]Formation of Invasion Complexes Using Multiple Pairs of Parallel-Stranded PNAs

○Naoya Mochizuki¹, Masanari Shibata¹, Yuichiro Aiba¹, Kota Ito¹, Shinya Ariyasu¹, Osami Shoji¹ (1. Nagoya University)

2:30 PM - 2:50 PM JST(5:30 AM - 5:50 AM UTC)Japanese

[[A]A303-1pm-05]Regulation of free heme by G-quadruplexes in mitochondrial long non-coding RNAs

○Ryohei Noizumi¹, Vinodh Josephbath Sahayasheela³, Mitsuharu Ooga¹, Ganesh Namasivayam Pandian², Toshikazu Bando¹, Hiroshi Sugiyama² (1. Kyoto University, 2. Kyoto University Institute for Integrated Cell-Material Sciences (iCeMS), 3. Keio University Human Biology-Microbiome-Quantum Research Center (Bio2Q))

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