Presentation Information

[[A]A404-3am-02]Strategy to increase the affinity of inhibitors to engineered adenosine A2A receptors for chemogenetic control

○Shinichi Oki1, Yuma Matsuoka2, Tomohiro Doura2, Shigeki Kiyonaka3 (1. School of Engineering, Nagoya University, 2. Graduate School of Engineering, Nagoya University, 3. Research Institute for Quantum and Chemical Innovation, Institute of Innovation for Future Society, Nagoya University)

Keywords:

G protein-coupled receptor,Adenosine A2A receptor,Chemogenetics,Cell type-specific control,Protein engineering