[[A]D401-1pm] 17. Biofunctional Chemistry, Biotechnology | The 105th CSJ Annual Meeting

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Academic Program [Oral A]17. Biofunctional Chemistry, Biotechnology : Oral A

[[A]D401-1pm]17. Biofunctional Chemistry, Biotechnology

Wed. Mar 26, 2025 1:00 PM - 3:40 PM JST
Wed. Mar 26, 2025 4:00 AM - 6:40 AM UTC

[A]D401(D401, Bldg. 4, Area 3 [4F])

1:00 PM - 1:10 PM JST(4:00 AM - 4:10 AM UTC)Japanese

[[A]D401-1pm-01]Liquid-liquid phase separation induced by i-motif structure under cell-mimicking conditions

○Ryosuke Suzuki¹, Mitsuki Tsuruta¹, keiko kawauchi¹, Daisuke Miyoshi¹ (1. FIRST,Konan University)

1:10 PM - 1:20 PM JST(4:10 AM - 4:20 AM UTC)Japanese

[[A]D401-1pm-02]Liquid-liquid phase separation and liquid-solid phase separation induced by DNA G-quadruplex

○Naoki Kosaka¹, Minori Nakata¹, Mitsuki Tsuruta¹, Keiko Kawauchi¹, Daisuke Miyoshi¹ (1. FIRST, Konan University)

1:20 PM - 1:30 PM JST(4:20 AM - 4:30 AM UTC)Japanese

[[A]D401-1pm-03]Regulation of liquid-liquid phase separation with G-quadruplex ligands

○Mizuho Aya¹, Tsuruta Mitsuki¹, kawauchi keiko¹, Miyoshi daisuke¹ (1. FIRST, Konan University)

1:30 PM - 1:40 PM JST(4:30 AM - 4:40 AM UTC)Japanese

[[A]D401-1pm-04]Interaction of zinc(II) pheophorbide a with G-quadruplex DNA

○Atsuya Momotake¹, China Okamoto^1,2, Masami Kobayashi¹, Yasuhiko Yamamoto¹ (1. Univ. of Tsukuba, 2. The National Institute of Advanced Industrial Science and Technology (AIST), National Metrology Institute of Japan (NMIJ))

1:40 PM - 1:50 PM JST(4:40 AM - 4:50 AM UTC)English

[[A]D401-1pm-05]New Data Science in Nucleic Acids Chemistry (16): Cellular compartment size as a critical factor in the stability and function of nucleic acids

○Sunipa Sarkar¹, Hisae Tateishi-Karimata ^1,2, Kazunori Matsuura ^3,4, Naoki Sugimoto ¹ (1. FIBER, Konan University, 2. FIRST, Konan University, 3. Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University, 4. Centre for Research on Green Sustainable Chemistry, Tottori University)

1:50 PM - 2:00 PM JST(4:50 AM - 5:00 AM UTC)English

[[A]D401-1pm-06]New Data Science in Nucleic Acids Chemistry (18): Comparison of the stability of DNA duplexes among normal and cancer cells

○Kun Chen¹, Hisae Tateishi-Karimata^1,2, Shuntaro Takahashi^1,2, Naoki Sugimoto¹ (1. Konan University FIBER, 2. Konan University FIRST)

2:00 PM - 2:10 PM JST(5:00 AM - 5:10 AM UTC)Japanese

[[A]D401-1pm-07]Construction of artificial viral capsid encapsulating quadruplex DNA and its intracellular delivery

○Kazunori Matsuura¹, Motono Ishii¹, Hiroshi Inaba¹, Tamaki Endoh², Hisae Karimata Tateishi², Naoki Sugimoto² (1. Graduate School of Engineering, Tottori University, 2. The Frontier Institute for Biomolecular Engineering Research, Konan University)

2:10 PM - 2:20 PM JST(5:10 AM - 5:20 AM UTC)

Break

2:20 PM - 2:30 PM JST(5:20 AM - 5:30 AM UTC)Japanese

[[A]D401-1pm-08]Synthesis of stimuli-responsive artificial oligodeoxynucleotides bearing phenylazothiazole groups and their application to gene regulation

○Kouki Tamura¹, Tatsuya Nishihara¹, Kazuhito Tanabe¹ (1. Aoyama Gakuin University)

2:30 PM - 2:40 PM JST(5:30 AM - 5:40 AM UTC)Japanese

[[A]D401-1pm-09]Design of oligodeoxynucleotides that selectively accumulated in hypoxic cells: Synthesis and functional evaluation

○Yusuke Sakurano¹, Reina Kainuma¹, Daigo Maehara¹, Tatsuya Nishihara¹, Kazuhito Tanabe¹ (1. Aoyama Gakuin University)

2:40 PM - 2:50 PM JST(5:40 AM - 5:50 AM UTC)Japanese

[[A]D401-1pm-10]Development and application of target responsive tetrahedral oligodeoxynucleotide with i-motif structure.

○Yui Kurozumi¹, Tatsuya Nisihara¹, Kazuhito Tanabe¹ (1. Aoyama Gakuin University)

2:50 PM - 3:00 PM JST(5:50 AM - 6:00 AM UTC)Japanese

[[A]D401-1pm-11]Function of nitrobenzyl group-tethered oligodeoxynucleotides with hypoxic cell accumulation properties

○Airi Kanayama¹, Daigo Maehara¹, Tatsuya Nishihara¹, Kazuhito Tanabe¹ (1. Aoyama Gakuin University)

3:00 PM - 3:10 PM JST(6:00 AM - 6:10 AM UTC)Japanese

[[A]D401-1pm-12]Exploring of Lipid Modification Unit to Improve Cell Membrane Permeability of Nucleic Acids

○Tento Sugiura¹, Akimitsu Okamoto¹ (1. The Univ. of Tokyo)

3:10 PM - 3:20 PM JST(6:10 AM - 6:20 AM UTC)Japanese

[[A]D401-1pm-13]Exploration of Nucleic Acid Design Methods Oriented to Induce Selective Cytotoxicity Using miRNAs as Biomarkers

○Hiroki Oiwa¹, Akimitsu Okamoto¹ (1. The Univ. of Tokyo)

3:20 PM - 3:30 PM JST(6:20 AM - 6:30 AM UTC)Japanese

[[A]D401-1pm-14]Effects of Spermidine and DNA topology for LLPS

○RYOTARO BUNYA¹, RYUSEI SENDA², RYU TASHIRO³, TAKANORI OYOSHI^1,2,4,5 (1. Faculty of science, Shizuoka University, 2. Graduate School of Integrated Science and Technology, Shizuoka Univercity, 3. Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, 4. Graduate School of Science and Technology, Shizuoka University, 5. Research Institute of Green Science and Technology, Shizuoka University)

3:30 PM - 3:40 PM JST(6:30 AM - 6:40 AM UTC)Japanese

[[A]D401-1pm-15]Analysis of a novel G-quadruplex binding protein, hexokinase 1

○Takumi Nakashima¹, Toshifumi Yamanaka², Wakana Matsudaira¹, Ahmed Mostafa Abdelhady^3,4, Shinichi Sato⁵, Kazumitsu Onizuka^3,4, Fumi Nagatsugi^3,4, Takanori Oyoshi^1,2,6,7 (1. Graduate School of Integrated Science and Technology, Shizuoka University, 2. Faculty of Science, Shizuoka University, 3. IMRAM, Tohoku University, 4. Graduate School of Science, Tohoku University, 5. Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, 6. Graduate School of Science and Technology, Shizuoka University, 7. Research Institute of Green Science and Technology, Shizuoka University)

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