[[A]D501-1am] 17. Biofunctional Chemistry, Biotechnology | The 105th CSJ Annual Meeting

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Academic Program [Oral B]17. Biofunctional Chemistry, Biotechnology : Oral B

[[A]D501-1am]17. Biofunctional Chemistry, Biotechnology

Wed. Mar 26, 2025 9:00 AM - 11:30 AM JST
Wed. Mar 26, 2025 12:00 AM - 2:30 AM UTC

[A]D501(D501, Bldg. 4, Area 3 [5F])

9:00 AM - 9:20 AM JST(12:00 AM - 12:20 AM UTC)Japanese

[[A]D501-1am-01]Development of subtype-selective labeling reagents for endogenous dopamine receptors in the live brain

○Hiroshi Nonaka^1,2, Takuma Takeshi¹, Seiji Sakamoto^1,2, Itaru Hamachi^1,2 (1. Graduate School of Engineering, Kyoto University, 2. ERATO, JST)

9:20 AM - 9:40 AM JST(12:20 AM - 12:40 AM UTC)Japanese

[[A]D501-1am-02]Creation of receptor-based fluorescent sensor and mapping of protease activity in live mouse brain.

○Seiji Sakamoto^1,2, Mengchu Wang¹, Kazuki Shiaiwa¹, Hiroshi Nonaka^1,2, Itaru Hamachi^1,2 (1. Graduate School of Engineering, Kyoto University, 2. JST ERATO)

9:40 AM - 10:00 AM JST(12:40 AM - 1:00 AM UTC)Japanese

[[A]D501-1am-03]In vivo protein labeling by ligand-directed ArNASA chemistry

○Tomonori Tamura¹, Masaharu Kawano¹, Dai Sugihara¹, Itaru Hamachi¹ (1. Kyoto University)

10:00 AM - 10:20 AM JST(1:00 AM - 1:20 AM UTC)English

[[A]D501-1am-04]Detection of dipeptidyl peptidase-4 activity in vivo with a rationally designed hyperpolarized MRI molecular probe

○Akihito Goto¹, Hiroyuki Yatabe¹, Abdelazim Elsayed Elhelaly³, Takayasu Sugiyma¹, Keisuke Saito¹, Norikazu Koyasu², Fuminori Hyodo³, Masayuki Matsuo³, Keita Saito⁴, Yoichi Takakusagi^4,5, Hiroshi Ishikita¹, Kazutoshi Yamamoto², Murali Cherukuri Krishna², Yutaro Saito¹, Shinsuke Sando¹ (1. The University of Tokyo, 2. National Institutes of Health, 3. Gifu University, 4. National Institutes for Quantum Science and Technology, 5. Chiba University)

10:20 AM - 10:30 AM JST(1:20 AM - 1:30 AM UTC)

Break

10:30 AM - 10:50 AM JST(1:30 AM - 1:50 AM UTC)English

[[A]D501-1am-05]Live-cell super-resolution imaging of mitochondrial inner membranes using a fast-blinking fluorophore

○Bochao Li¹, Toshiyuki Kowada¹, Takahiro Fujiwara², Shin Mizukami¹ (1. Tohoku University, 2. Kyoto University)

10:50 AM - 11:10 AM JST(1:50 AM - 2:10 AM UTC)English

[[A]D501-1am-06]Development of optochemogenetic technology for regulating intracellular droplet formation

○Muhammad Wildan Saifudin¹, Toshiyuki Kowada^1,2, Hayashi Yamamoto³, Shin Mizukami^1,2 (1. Graduate School of Life Sciences, Tohoku University, 2. Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 3. Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School)

11:10 AM - 11:30 AM JST(2:10 AM - 2:30 AM UTC)English

[[A]D501-1am-07]Degradation of lipid droplets by in-cell self-assembly of autophagy-tethering chimeras

○Yi DING¹, Ira NOVIANTI^1,2, Toshiyuki KOWADA^1,2, Shin MIZUKAMI^1,2 (1. Graduate School of Life Sciences, Tohoku University, 2. Institute of Multidisciplinary Research for Advanced Materials, Tohoku University)

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