Presentation Information

Japanese

[P1-3am-08]Synthesis of PROTAC using triterpenoids and evaluation of cytotoxic activity against tumor cells

○Komei Naruse¹, Haruto Ikegami², Reo Okano², Kazusa Kirihara², Suzuka Shimoda², Ui Mori², Hiroyuki Akazawa³, Motohiko Ukiya² (1. Materials and Applied Chemistry, Graduate School of Science and Technology Nihon University, 2. Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, 3. Department of Science and Manufacturing Technology, Nihon University Junior College)

Keywords:

Triterpenoids,PROTAC,Ubiquitin-proteasome system,Antitumor activity,Target protein

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