Presentation Information

4:00 PM - 4:15 PM JST(7:00 AM - 7:15 AM UTC)

[9p-N307-10]Long-Term t-SPESI Mass Spectrometry Imaging Using Fluorinated Probes

〇(M1)Takao Yasuda¹, Kato Tasuku², Otsuka Yoichi¹, Michisato Toyota¹ (1.Graduate School of Science, Univ. Osaka, 2.School of Science, Univ. Osaka)

Keywords:

Mass Spectrometry Imaging

We have developed tapping-mode scanning probe electrospray ionization (t-SPESI), which enables the extraction and ionization of analytes using a vibrating quartz capillary probe and a small amount of solvent, and have applied it to mass spectrometry imaging (MSI) of biological tissues. However, during long-term measurements, the accumulation of biological components at the probe tip leads to flow path clogging. In this study, we fabricated a fluorinated probe and evaluated its effectiveness for long-term MSI.

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