[15a-P04-1~13] 12.6 Nanobiotechnology

[15a-P04-10] Development of DNA storage using nanopores and PNA

〇(M1)Wataru Tsuchiya¹, Yuichiro Aiba², Hirohito Yamazaki^1,3 (1.Nagaoka Univ. of Tech., 2.Nagoya Univ., 3.Nagaoka Univ. of Tech. Top Runner Incubation Center for Academia-Industry Fusion.)

Keywords:

Nanopore,DNA Storage

With the advent of an information explosion era, the development of large-capacity, long-term storage information recording technology has become an urgent research topic. In this study, we develop a new DNA storage method that combines DNA coding using peptide nucleic acid (PNA) and reading the coding using nanopore measurement. Experiments have demonstrated that DNA storing 1 bit of data can be read using the same nanopore. In the future, we aim to achieve 2-bit data by binding modified PNA to DNA.