[15p-K306-1~10] 3.3 Biomedical optics

4:00 PM - 4:15 PM JST(7:00 AM - 7:15 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation Award

[15p-K306-9] In-vitro experiments with biological phantoms for depth estimation of cancer invasion using circularly polarized light scattering

〇(M1)Mike Raj Maskey¹, Mitsuo Fukuno¹, Akane Saito¹, Asato Esumi¹, Nozomi Nishizawa¹ (1.Kitasato Univ.)

Keywords:

Circularly polarized light,Optical biopsy,Light scattering

Depolarization of circularly polarized light in biological tissues depends on the ratio of cancerous cell in the tissue, which is useful for investigating the depth of cancer invasion. In order to bridge the divergence between the experiments with actual biological tissues and the theoretical calculations, we fabricated phantoms without contributions of biological complexity, and investigated the optical response against irradiation of circularly polarized light. The phantoms having two layers imitating cancerous and healthy tissues show the changes depending on the thickness of cancerous layer on the depolarization of circularly polarized light, indicating the possibility of depth estimation of cancer invasion by this method.