Presentation Information
[16p-K406-1][The 57th Young Scientist Presentation Award Speech] Development of Thin-Film Light-Emitting Devices using Flexible Electronics for the Realization of Metronomic Photodynamic Therapy
〇Masato Saito1, Daiki Tokura2, Yasufumi Yokoshiki3, Takashi Tokuda4, Takahiro Nomoto2, Toshinori Fujie1,5 (1.Sch. Life Sci. and Tech,,Tokyo Tech, 2.Grad. Sch. Arts and Sci., UTokyo, 3.Coll. Sci. and Tech, Aoyama Gakuin Univ., 4.Sch. Eng., Science Tokyo, 5.ASMat, Science Tokyo)
Keywords:
Polymeric Thin-Film,Flexible Electronics,Photodynamic Therapy
Metronomic photodynamic therapy (mPDT) is a type of PDT that aims to exert an anti-tumor effect by continuously irradiating a photosensitizer with weak light. In this study, we developed a flexible light-emitting device using flexible electronics technology to apply mPDT to deep tissues of the body. Specifically, we fabricated a thin-film light-emitting device by transferring printed wiring onto a polylactic acid thin film. We verified its anti-tumor effect in cancer cells and tumor-bearing model mice.
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