Presentation Information
[17a-K402-7]Analysis of Extracellular Vesicles with Plasmonic Chips Immobilized with Capture Antibodies for Cancer Marker
〇(M1)Tatsuki Iwamura1, Makoto Tokami1, Yasunori Nawa1, Keiko Tawa1 (1.Kwansei Gakuin Univ.)
Keywords:
plasmon,immunosensor,exosome
Exosomes (Extracellular vesicles :EV) secreted from cells include various proteins, and it is possible to predict the diseases that will afflict in the future.
However, it is difficult to detect a single Ev with about 100 nm diameter with an optical macroscope.
In our laboratory, a single Ev was detected by fluorescence microscopy using a plasmonic chip with wavelength size periodic structures covered with a metallic film.
In this study, Evs were analyzed with a plasmonic chip immobilized with a capture antibody for CD326 (EpCAM), a cancer marker.
However, it is difficult to detect a single Ev with about 100 nm diameter with an optical macroscope.
In our laboratory, a single Ev was detected by fluorescence microscopy using a plasmonic chip with wavelength size periodic structures covered with a metallic film.
In this study, Evs were analyzed with a plasmonic chip immobilized with a capture antibody for CD326 (EpCAM), a cancer marker.
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