Presentation Information
[17a-K403-8]Localized immobilization technique for bioreceptors on optical interferometric MEMS biosensor arrays using aldehyde-functionalized polypyrrole
〇(M1)Masaki Oshino1, Jyunki Hirano1, Chihiro Kurosu1, Yong joon Choi1, Toshihiko Noda1, Kazuaki Sawada1, Kazuhiro Takahashi1 (1.Toyohashi Tech.)
Keywords:
Biosensor,MEMS,Electropolymerization
We propose the coating of antibodies on MEMS array sensors for multi-parameter measurement of biomarkers. In previous studies, local antibody modification has been achieved by electropolymerization of NHS pyrrole.
However, non-water-soluble NHS pyrrole requires the use of acetonitrile, which deactivates the antibody and makes it difficult to sequentially coat multiple types of antibodies.
In this study, we investigated a method using aldehyde pyrrole by electropolymerization in pure water and evaluated the feasibility of multi-measurement.
However, non-water-soluble NHS pyrrole requires the use of acetonitrile, which deactivates the antibody and makes it difficult to sequentially coat multiple types of antibodies.
In this study, we investigated a method using aldehyde pyrrole by electropolymerization in pure water and evaluated the feasibility of multi-measurement.
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