[17p-K403-1~13] 12.7 Biomedical Engineering and Biochips

1:30 PM - 1:45 PM JST(4:30 AM - 4:45 AM UTC)

[17p-K403-3] Development of multifunctional probes technology for in vivo photopharmacology experiments

〇Kazuki Moriya¹, Gota Shinohara¹, Daiki Yano¹, Atsushi Nishikawa², Alexander Loesing², Noriaki Ohkawa³, Hiroto Sekiguchi¹ (1.Toyohashi Tech, 2.ALLOS, 3.Dokkyo Med. Univ.)

Keywords:

Photopharmacology,MicroLED,Neural electrode

In recent years, methods of intervening in neural activity based on photopharmacology have been attracting attention in order to elucidate brain function. We have conducted photopharmacological experiments using LED probes in anesthetized mice and demonstrated that light irradiation activates EEG activity in a specific frequency range. Based on these results, we report on the development of a flow path/electrode probe and its junction technology with the LED probe to realize a hybrid junction probe that integrates light irradiation, drug administration, and potential recording.