Session Details
[3P-2]Poster Presentation
Fri. Nov 29, 2024 12:55 PM - 2:55 PM JST
Fri. Nov 29, 2024 3:55 AM - 5:55 AM UTC
Fri. Nov 29, 2024 3:55 AM - 5:55 AM UTC
Poster & Exhibition Venue 2 (Marine Messe Fukuoka Hall B, 1F)
3. Development and Regeneration
- a. Organogenesis / Morphogenesis / Regeneration
- b. Stem Cell
- c. Cell Differentiation
- d. Early Development
- e. Reproduction
- f. Others
4. Animal and Plant Physiology, and Diseases
- a. Symbiotic Microorganism
- b. Biological Rhythm
- c. Brain / Nervous System / Neurodevelopment / Structure
- d. Brain / Nervous System / Behavior
- e. Brain / Nervous System / Disorder
- f. Immunity
- g. Infection / Virus
- h. Aging
- i. Cancer Cell
- j. Cancer Tissue / Cancer Therapeutics
- k. Metabolism / Nutrition
- l. Genetic Disorder
- m. Plant
- o. Others
- a. Organogenesis / Morphogenesis / Regeneration
- b. Stem Cell
- c. Cell Differentiation
- d. Early Development
- e. Reproduction
- f. Others
4. Animal and Plant Physiology, and Diseases
- a. Symbiotic Microorganism
- b. Biological Rhythm
- c. Brain / Nervous System / Neurodevelopment / Structure
- d. Brain / Nervous System / Behavior
- e. Brain / Nervous System / Disorder
- f. Immunity
- g. Infection / Virus
- h. Aging
- i. Cancer Cell
- j. Cancer Tissue / Cancer Therapeutics
- k. Metabolism / Nutrition
- l. Genetic Disorder
- m. Plant
- o. Others
[3P-529]FEM Analysis of formation in the epithelial cell layer determining the pattern of tracheal cartilage
○Nozomi Hasegawa1, Kana Furukawa2, Hironori Takeda3, Daiki Matsunaga1, Shinji Deguchi1 (1. Oasaka Univ., Grad. Sch. of Eng. Sci., Div. Bioeng., 2. Osaka Univ., INSD, 3. Kyoto University, LiMe, Biomechanics)
[3P-530]Histochemical Immunohistochemical Analysis of MUC1+/MUC2 and MUC5AC- Membrane Associated Mucins in the Intraepithelial Surface Mucous Cells of the Developing Rabbit Esophagus
○Mahmoud Awad1,2, Wafaa Gaber3, Makoto Hirayama1, Dalia Mohamedien2,4 (1. Graduate School of Integrated Science for Life, Hiroshima University, 739-8528, Higashihiroshima, Japan, 2. Department of Histology, Faculty of Veterinary Medicine, South Valley University, 83523, Qena, Egypt, 3. Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt , 4. Amphibian Research Center, Hiroshima University, Hiroshima, Japan)
[3P-531]Evolutionary conserved mechanisms of rostral interhemispheric remodeling in amniotes
○Ryota Noji1, Hiroshi Kiyonari2, Mari Kaneko2, Takaya Abe2, Takuma Kumamoto3, Hitoshi Gotoh1, Chiaki Ohtaka-Maruyama3, Katsuhiko Ono1, Tadashi Nomura4 (1. Department of Biology, Kyoto Prefectural University of Medicine, 2. Laboratory for Animal Resources and Genetic Engineering, RIKEN BDR, 3. Developmental Neuroscience Project, Department of Brain and Neurosciences, Tokyo Metropolitan Institute of Medical Science, 4. Applied Biology, Kyoto Institute of Technology)
[3P-532]Development of tissue engineering materials inducingg lymphatic vessels regeneration and application to lymphedema treatment
○Tatsuya Dode1, Koji Nagahama2 (1. Graduate school of Frontiers of Innovative Research in Science and Technology, Konan University, 2. Frontiers of Innovative Research in Science and Technology, Konan University)
[3P-533]Modeling human retinal vascular pattern around foveal avascular zone
○Kotaro yoshimura Yoshimura1, Kei Sugihara1, Ichiro Maruko2, Tomohiro Iida2, Takashi Miura1 (1. Department of Anatomy and Cell Biology, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan., 2. Department of Ophthalmology, Tokyo Women's Medical University, Tokyo, Japan)
[3P-534(3PS-02-03)]Generation of skin graft in vivo by cell competition.
○Hisato Nagano1, Naoaki Mizuno1,2, Hideyuki Sato1, Eiji Mizutani3, Ayaka Yanagida4, Mayuko Kano5, Mariko Kasai1, Hiromi Yamamoto1, Motoo Watanabe1, Suchy Fabian6, Hideki Masaki1, Hiromitsu Nakauchi1,6 (1. Tokyo Medical and Dental University, Stem Cell Therapy Laboratory, 2. Tokyo Medical and Dental University, Center for Experimental Animals, Department of Experimental Animal Model for Human Disease, 3. University of Tsukuba, Laboratory of Stem Cell Therapy, 4. The University of Tokyo, Department of Veterinary Anatomy, 5. St. Marianna University School of Medicine, Metabolism and Endocrinology, Department of Medicine, 6. Stanford University, Institute for Stem Cell Biology and Regenerative Medicine)
[3P-535]Morphogenesis of the carapace from phyllosoma to puerulus
○Haruhiko Adachi1,3, Kentaro Morikawa2, Yasuhiro Inoue2, Shigeru Kondo3 (1. Keio Univ., IAB, 2. Kyoto Univ., Grad. Sch. Sci. Eng., 3. Osaka Univ., FBS)
[3P-536(3AS-10-02)]Heterogeneous ECM dynamics regulate cell survival and abdominal epithelium remodeling in Drosophila
○Kevin Yuswan1, Daiki Umetsu2, Erina Kuranaga1,3 (1. Laboratory of Histogenetic Dynamics, Graduate School of Life Science, Tohoku University, 2. Laboratory of Cell Biology, Department of Biological Sciences, Graduate School of Science, Osaka University, 3. Laboratory for Histogenetic Dynamics, Graduate School and Faculty of Pharmaceutical Sciences, Kyoto University)
[3P-537]Understanding the physiological function of the Hippo pathway in mammals
○Akihiro Nita1, Hao Li1, Toshiro Moroishi1 (1. Kumamoto university)
[3P-538]Pattern formation of abdominal muscle in amphibian larvae
○Maho Yoshimoto1, Ryuji Toyoizumi1,2 (1. Dept. Biol. Sci., Grad. Sch. Sci., Kanagawa Univ., 2. Res. Inst. Integr. Sci., Kanagawa Univ)
[3P-539]Analysis of the mechanism of cell migration control by the neuropeptide FLP-10C in C. elegans
○FEIFEI SUN1, SHIBATA YUKIMASA1, NISHIWAKI KIYOJI1 (1. Kwansei Gakuin University)
[3P-540]Development of a low-cost, 3D-printed live imaging system for analyzing gene expression dynamics in growing biofilms
○Ryunosuke Sakai1, Yifan Zhao1, Martin Robert1 (1. Kyoto university)
[3P-541]The phosphatase Ctdnep1 prevents excessive osteoclastogenesis through negative regulation of RANKL signaling and Nfatc1 protein levels
○Takuto Konno1, Hitomi Murachi1, Kanon Otsuka1, Yuta Kimura1, Chisato Sampei1, Yasuhiro Arasaki1, Yukihiro Kohara1, Tadayoshi Hayata1 (1. Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences and Faculty of Pharmaceutical Science, Tokyo University of Science)
[3P-542]Explore the function of YY1 and YY1B in planarian regeneration
○Ya Zhang1 (1. Tohoku University)
[3P-543(3PS-02-02)]Recapitulation of first pharyngeal arch-specific regional patterning and generation of oral organs using human induced pluripotent stem cells
○Souta Motoike1, Yoshiko Inada1, Junya Toguchida2, Mikihito Kajiya3, Makoto Ikeya1 (1. Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, 2. Department of Fundamental Cell Technology, Center for iPS Cell Research and Application, Kyoto University, 3. Department of Innovation and Precision Dentistry, Hiroshima University Hospital)
[3P-544]Elucidation of Mechanisms Underlying Mucin Barrier Regulation by Gut Microbiota
○Riho Furukawa1,2, Eiji Miyauchi2, Chihiro Mogi2, Kota Uchiyama2, Syunsuke Shimizu1,2, Nobuo Sasaki2 (1. Grad Sch. of Med., Gunma Univ., 2. Lab of Mucosal Ecosystem Design, Institute for Molecular and Cellular Regulation, Gunma Univ.)
[3P-545]Mechanism of angiogenesis induced by 3D-printed magnesium composite scaffolds in bone organoid.
○HSIN YU HSU1, Tzu Hui Chu1, Yu Chih Lo1, Yao Chuan Wang1, Hsuan Hsuan Wang1, Cheng Yong Huang1, Jia Fwu Shyu1 (1. National Defense Medical Center)
[3P-546]Ecdysteroids promote embryonic apotosis in Drosophila dorsal closure.
○Hitoshi Tokushige1, Yuki Taira1, Raizou Sasahara1, Yuji Kageyama1,2 (1. Dept Biol, Fac Sci, Kobe Univ, 2. Biosignal Res Ctr, Kobe Univ)
[3P-547]Genome-Wide Discovery of Enhancers that Regulate Region-Specific Transcription during Cardiac Development
○Yukihiro Harada1, Yunce Wang2, Akiyasu Iwase3, Yoshiki Hisayasu2, Mizuki Arimoto2, Tomoe Ueyama4, Manabu Shirai5, Yusuke Watanabe6, Hiroki Kurihara3,7, Osamu Nakagawa8, Teruhisa Kawamura1 (1. Dept. of Biomed. Sci., Col. of Life Sci., Ritsumeikan Univ., 2. Grad. Sch. of Life Sci., Ritsumeikan Univ., 3. Isotope Sci. Center, Univ. of Tokyo, 4. Res. Organiz. of Sci Technol., Ritsumeikan Univ., 5. ORC, OIC, NCVC, 6. Dept. of Cardiac Regen. Biol., Res. Inst., NCVC, 7. IRCMS, Kumamoto Univ., 8. Dept. of Genom. Med., Res. Inst., NCVC)
[3P-548]Mobility-induced fluctuation of developmental patterns
○Koichiro Uriu1 (1. Tokyo Tech.)
[3P-549]Identification of a mechanical cue that leads to the left-right asymmetric morphogenesis of the embryonic midgut.
○Takamasa Higashi1, Dongsun Shin1, Mitsutoshi Nakamura1, Florian Neugebauer1, Takuya Nomura1, Kenji Matsuno1 (1. Osaka University)
[3P-550]Morphological and functional classification analysis of Parathyroid cells
○Norifumi Tatsumi1, Sahoko Kamejima2, Taku Yamada1, Masataka Okabe1 (1. Dept. of Anat., Jikei Univ. Sch. of Med., 2. Div. of Nephrology and Hypertension, Dept. of Internal Med., Jikei Univ. Sch. of Med.)
[3P-551]Gap junction protein Connexin 43 regulates ameloblast polarization in tooth development
○Akane Shimada1, Keigo Yoshizaki2,3, Tian Tian1,3, kanji Mizuta2, Junpei Kawahara2, Shao Shuai2, Mio Nakanishi1, Ichiro Takahshi2,3, Satoshi Fukumoto1,3 (1. Department of Pediatric Dentistry, Graduate School of Dentistry, Kyushu University, 2. Department of Orthodontics, Graduate School of Dentistry, Kyushu University, 3. Dent-craniofacial Development and Regeneration Research Center, Faculty of Dentistry, Kyushu University)
[3P-552(3PS-04-02)]Generation of the organotypic kidney structure solely from pluripotent stem cells
○Shunsuke Tanigawa1, Etsuko Tanaka2, Ryuichi Nishinakamura1 (1. Kumamoto University, 2. University of Miyazaki)
[3P-553(3AS-10-04)]Molecular chaperone GRP94 is involved in osteoblast differentiation.
○RInna Kanai1, Naoya Saeki1, Sayuri Tatsuta1, Tomoko Sumitomo2, Shinsuke Ohba1, Makoto Abe1 (1. Osaka Univ., 2. Tokushima Univ.)
[3P-554]Regulation of heat stress-induced autophagy via Dcp-1 in Drosophila ovary
○Masanori Mukai1,2, Naoya Yoshida1, Yuto Kikuoka1, Junnki Watanabe2 (1. Konan Univ., 2. Graduate school of Konan Univ.)
[3P-555]Elucidation of the role of ErbB in the maturation of the cardiac ventricular wall
○Maretoshi Hirai1, Keita Fujiwara1 (1. Kansai Medical University)
[3P-556]Using a novel zebrafish mutant, functional analysis of a gene that forms the orientation of collagen fibers as the frame in fish fin building
○Rintaro Tanimoto1, Takeshi Itabashi2, Atsuko H Iwane2, Kondo Shigeru1, Junpei Kuroda1 (1. Graduate School of Frontier Biosciences, Osaka Univ., 2. RIKEN BDR)
[3P-557]Guidance cues for the central arteries during zebrafish hindbrain development.
Naoki Hirano, Hayato Endo, ○Misato Fujita1 (1. Kanagawa University)
[3P-558]Synchronization of rhythmic contraction in primary polyps of Clytia hemisphaerica
○Yuuki Shikaya1, Tsuyoshi Momose1 (1. CNRS/Sorbonne Univ., IMEV, LBDV)
[3P-559]From Supplementary to Central: The potential of High-Resolution Image-Based Spatial Transcriptomics with Xenium 5K panels
○Junhyeong Kim1, Mitsuru Morimoto1 (1. Laboratory for lung development and regeneraiton・BDR・RIKEN)
[3P-560]ROS produced by Dual oxidase regulate cells proliferation and hemocytes migration during leg regeneration in the cricket Gryllus bimaculatus
○Tetsuya Bando1, Misa Okumura1, Hideyo Ohuchi1 (1. Okayama Univ)
[3P-561]Morphogenesis of the chicken ceca
○Shota Utsunomiya1, Rintaro Kawasaki1, Masafumi Inaba1, Yoshiko Takahashi1 (1. Kyoto University)
[3P-562]scRNA-seq analysis for functional characterization of macrophages in muscle tissue remodeling
○Kotomi Okuno1, Kenji Matsuno1, Daiki Umetsu1 (1. Osaka Univ.)
[3P-563]Identification of thyroid hormone receptor-target genes involved in hindlimb formation
○Shuhei Ogawa1,2, Keisuke Nakajima1,2, Nobuaki Furuno1,2, Ichiro Tazawa1,2 (1. Program of Basic Biology・Graduate School of Integrated Sciences for Life・Hiroshima Univ., 2. Hiroshima Univ. Amphibian Research Center)
[3P-564]Investigating a new mechanism of heartbeat regulation in Drosophila
○Ryota Akimoto1, Erina Kuranaga1,2, Sayaka Sekine1 (1. Laboratory for Histogenetic Dynamics, Graduate School of Life Sciences, Tohoku University, 2. Graduate School of Pharmaceutical Sciences, Kyoto University)
[3P-565(3PS-02-10)]Novel Transcriptome Dynamics Revealed by Time-Series RNA-Seq Analysis during Reprogramming of Somatic Cells
○Satomi Masai1,2, Yasuhiro Yunoki1, Weipeng Shi1,2, Kohei Ishihara1, Yuki Sasaki1, Risa K Kawaguchi1, Masato Nakagawa1 (1. CiRA, Kyoto Univ., 2. Grad. Sch. of Med., Kyoto Univ.)
[3P-566(3AS-07-03)]Understanding ES cell characteristics by integrating single-colony proteomics and quantitative analysis of colony images
○Ayaka Kakihara1, Atsushi Hatano1, Masaki Matsumoto1 (1. Dept. Omics Sys. Biol., Grad. Sch. Med. Dent. Sci., Niigata Univ.)
[3P-567(3PS-02-05)]Ex vivo amplification of human iPSC-derived hematopoietic stem/progenitor cells by a modified Lhx2 transcription factor
○Kenji Kitajima1, Takahiko Hara1,2,3 (1. Tokyo Metropolitan Institute of Medical Science, 2. Tokyo Medical and Dental Univ., 3. Tokyo Metropolitan Univ.)
[3P-568]Analysis of mitophagy activity in the quiescent state of neural stem cells.
○Rina Onishi1,2, Yasushi Saeki1, Taeko Kobayashi1 (1. Division of Protein Metabolism, The Institute of Medical Science, The University of Tokyo, 2. Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University)
[3P-569]Analysis of the CD133-positive neural stem cells
○Yuka Noji1, Takuma Shinozuka1, Toru Kondo2, Noriaki Sasai1 (1. Dev. Biomed. Sci., NAIST., 2. IGM, Hokkaido Univ.)
[3P-570(3PS-02-14)]Functional analysis and therapeutic applications of Ephrin receptors expressed in human pluripotent stem cells
○Atsushi Intoh1, Akira Kurisaki1 (1. Nara Institute of Science and Technology)
[3P-571]Elucidating the roles of retinoic acid signaling in the regulation of epidermal stem cell population balance in the skin
○Thisakorn Dumrongphuttidecha1,2, Mizuho Ishikawa1,2, Nina Cabezas-Wallscheid3,1, Aiko Sada1,2 (1. International Research Center for Medical Sciences (IRCMS), 2. Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan, 3. Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany)
[3P-572]Transplantation of human iPS-derived cartilage tissue into large animals for clinical application.
○Yuki Fujiswa1, Shota Takihira1,2, Tomoka Takao1, Daisuke Yamada1, Tomoyuki Ota1,3, Yohei Kitaguchi1,3, Ryosuke Iwai4, Tomohiro Inoue1,2, Eiji Nakada2, Yoshihiro Kimata3, Toshifumi Ozaki2, Takeshi Takarada1 (1. Department of Regenerative Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2. Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 3. Department of Plastic and Reconstructive Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 4. Institute of Frontier Science and Technology, Okayama University of Science)
[3P-573]The effects of extracellular Syntaxin4/basement membrane components in ES cells
○Toshiki Tanaka1, Yohei Hirai1 (1. Kwansei Gakuin univ. School of biological and environmental science, Dept. Biomedical science)
[3P-574]The activity of transcription factor E2F in the embryonic cell cycle
○Masaru Kitagawa1, Kiyoshi Otani1 (1. Kwansei Gakuin University Graduate School)
[3P-575]Functional Analysis of a STAT3 inhibitor in the Regulation of Self-Renewal in Mouse ES Cells
○Yuta Aoki1, Aoi Kurogi1, Takeshi Matsuo1, Sae Kuroki2, Yumi Horiuchi2, Tadayuki Akagi1,2 (1. Fukuoka Institute of Technology, 2. Fukuoka Institute of Technology Univ.)
[3P-576(3PS-02-12)]Translation Initiation Factor EIF3H is Essential for Maintaining Pluripotency in Human Pluripotent Stem Cells
○Satoshi Suzuki1, Chikako Okubo1, Michiko Nakamura1, Mari Hamao1, Kazutoshi Takahashi1 (1. Kyoto University, Ctr.for iPS cell res. appl. (CiRA))
[3P-577]Elucidating the role of glycosylation in epidermal stem cell aging
○Trisha Biswas Shanta1,2, Nguyen Thi Kim Nguyen1, Erna Raja3,1, Lalhaba Oinam3, Ahmed Gamal Kamel Habib1,5, Hiromi Yanagisawa3,6, Hiroaki Tateno4, Aiko Sada1,2,3 (1. IRCMS, Kumamoto University, 2. MIB, Kyushu University, 3. TARA, University of Tsukuba, 4. Cell. and Mol. Biotech. Recr. Inst., AIST, 5. Beni-suef University, 6. Faculty of Medicine, University of Tsukuba)
[3P-578(3AS-07-07)]Nutrient-dependent dedifferentiation in the intestinal epithelium promotes adaptive growth in Drosophila
Hiroki Nagai1,3, Luis Augusto Eijy Ngai2, Ryuichiro Nakato2, Masayuki Miura1, ○Yuichiro Nakajima1 (1. Grad Sch Pharm Sci, Univ. Tokyo, Japan, 2. IQB, Univ. Tokyo, Japan, 3. ISTA, Austria)
[3P-579]Mutant transcription factor C/EBPε dysfunction and immunodeficiency
○TOMOYA Tamaru1, Yume Maruoka2, Rina Katayama2, Juna Momokino2, Atushi Ueda3, Aaqib Zaffer Banday4, Taizo Wada5, Hirokazu Kanegane6, Tadayuki Akagi1,2 (1. Fukuoka Institute of Technology, 2. Fukuoka Institute of Technology Univ., 3. Tokai Univ., 4. GMC Srinagar, Pediatrics, India, 5. Kanazawa Univ., 6. Tokyo Medical and Dental Univ.)
[3P-580]Silence is golden: iPSC-specific gene noises lead to human pluripotency defects
Keiko Hiraki-Kamon1, ○Hidemasa Kato1, Makoto Motono2, Masayoshi Kamon1, Yoichi Kondo2 (1. Ehime University, 2. Osaka Medical and Pharmaceutical University)
[3P-581]Identification and visualization of gastric stem cells by a quiescence gene p57
○Tsunaki Higa1, Keiichi I. Nakayama1 (1. Lab. Anticancer Strategies, Advanced Res. Inst., Inst. Sci. Tokyo)
[3P-582]Hemogenic endothelial cells expressing BMP receptors differentiate into hematopoietic stem cells
○Mariko Tsuruda1, Saori Morino-Koga1, Xueyu Zhao1, Minetaro Ogawa1 (1. Dept. of Cell Diff., IMEG, Kumamoto Univ.)
[3P-583]Analysis of clonal differentiation dynamics of single hematopoietic stem cell using mathematical models
○Shoya Iwanami1 (1. Nagoya University)
[3P-584]The effect of aberrant DNA methylation of a myogenic regulatory factor, MYF5 in human iPS cells on muscle differentiation.
○Masayoshi Kamon1, Keiko Hiraki-Kamon1, Makoto Motono2, Hidemasa Kato1 (1. Ehime Univ., 2. Osaka Medical and Pharmaceutical Univ.)
[3P-585]Study on the optimization of in utero hematopoietic stem cell transplantation via placental route
○Hyojung Jeon1, Michito Hamada2, Satoru Takahashi2, Satoshi Yamazaki1 (1. IMSUT, The University of Tokyo, 2. Institute of Medicine ,University of Tsukuba)
[3P-586]Identification of genes that enhance direct reprogramming of human pancreatic beta cells.
○Hideki Endoh1, Ruslan Deviatiiarov1, Oleg Gusev1, Keishiro Nishimura1, Kanako Sakaeda3, Yohichi Yasunami1, Hideo Saotome1,2, Yasushi Okazaki1,2, Masahito Matsumoto1,2 (1. IDRC., Grad.Sch.of Med., Juntendo Univ. , 2. Direct Rep.Regene.Med., Grad.Sch.of Med.,Juntendo Univ., 3. Central Research Lab., Sysmex Corp.)
[3P-587]Studies on genes that promote differentiation of human somatic cells into insulin-producing cells by direct reprogramming
○Keishiro Nishimura1, Hideki Endoh1, Ruslan Deviatiiarov1, Oleg Gusev1, Yasuhiro Irino3, Hideo Saotome1, Yasushi Okazaki1,2, Masahito Matsumoto1,2 (1. IDRC., Grad.Sch.of Med., Juntendo Univ., 2. Direct Rep.Regene.Med., Grad.Sch.of Med.,Juntendo Univ., 3. Central Research Lab., Sysmex Corp.)
[3P-588]Towards Understanding of the Mechanisms of Gliogenesis in the Mammalian Developing Cerebral Cortex Using Single-Cell RNA-seq Data
○Sora Kawarada1, Hayato Uchida2, Mizuki Honda1,2, Fumihiro Morishita1,2, Takuya Imamura1,2 (1. Dept of Biological Sci, Hiroshima Univ., 2. Grad Sch of Integrated Sci for Life, Hiroshima Univ.)
[3P-589(3AS-07-02)]Differences of developmental origin between neural crest and non-neural crest-derived cellswith fate-determining mechanisms of constituting the cardiopharyngeal region
○Akiyasu Iwase1,2,3, Yasunobu Uchijima1, Daiki Seya1, Mayuko Kida1, Hiroki Higashiyama1, Kazuhiro Matsui1, Akashi Taguchi2, Shogo Yamamoto4, Shiro Fukuda4, Seitaro Nomura5, Takahide Kohro6, Chisa Shukunami7, Haruhiko Akiyama8, Masahide Seki9, Akinori Kanai9, Yutaka Suzuki9, Yukihiro Harada10, Teruhisa Kuwamura10, Osamu Nakagawa10,11, Youichiro Wada2, Hiroyuki Aburatani4, Yukiko Kurihara1,2,12, Sachirko Miyagawa-Tomita1,13, Hiroki Kurihara1,2,3 (1. Dept. of Phys. chem. and Metab., Grad. Sch. of Med., Univ. of Tokyo, 2. ISC, Univ. of Tokyo, 3. IRCMS, Kumamoto Univ., 4. Genome Sci. Div., RCAST, Univ. of Tokyo, 5. Dept. of Card. Med., Grad. Sch. of Med., Univ. of Tokyo, 6. Dept. of Clin. Info., Jichi Med Univ, 7. Dept. of Mol. Bio. and Biochem., Grad. Sch. of Biomed. and Health Sci. Hiroshima Univ, 8. Dept. of Orthop. Surg., Gifu Univ., 9. Dept. of. Med. Genome. Sci., Grad. Sch. of Front Sci., Univ. of Tokyo, 10. Dept. of Biomed. Sci., Col. of Life Sci., Ritsumeikan Univ., 11. Dept. of Genom. Med., Res. Inst., NCVC, 12. Kagawa Nutrit. Univ., 13. Dept. of Animal Health Tech., Yamazaki Univ. Animal Health Tech)
[3P-590]Notch-dependent functional conversion of RUNX transcription factors regulates the initiation of T-lineage program
○Hiroyuki Hosokawa1 (1. Department of Immunology, Tokai University School of Medicine)
[3P-591]Actin-related protein 5 inhibits cardiac and skeletal muscle differentiation
○Tsuyoshi Morita1, Ken'ichiro Hayashi2 (1. Wakayama Med. Univ. , 2. Yamaguchi Univ.)
[3P-592(3PS-02-06)]Directed differentiation of human pluripotent stem cells into organ-specific mesenchyme of the diverse foregut-derived organs
○Keishi Kishimoto1,2,3, Mitsuru Morimoto1,2, Aarom M Zorn2,3 (1. Laboratory for Lung Development, RIKEN BDR, 2. CuSTOM-RIKEN BDR Collaborative Laboratory, Cincinnati Children’s Hospital, 3. Center for Stem Cell and Organoid Medicine (CuSTOM), Perinatal Institute, Division of Developmental Biology, Cincinnati Children’s Hospital)
[3P-593(3PS-02-11)]Control of cell fate by manipulation of dynamics of gene regulatory network
○Yusuke Tarumoto1, Seiichi Sugino1, Yuhei Yamauchi1, Masato Ishikawa1, Yusuke Seto1, Fumi Wagai1, Mototsugu Eiraku1, Atsushi Mochizuki1, Kosuke Yusa1 (1. LiMe, Kyoto Univ.)
[3P-594]Expression analysis of bile acid transporter SLC10A2 using human ileum-derived organoids
○Kota Yanagisawa1,2, Eiji Miyauchi1, Takayuki Saitoh2, Yuki Takashima3, Shoko Kobayashi3, Nobuo Sasaki1 (1. Gunma University Institute for Molecular and Cellular Regulation Mucosal Ecosystem Design Lab, 2. Gunma University Graduate School of Health Sciences, 3. The University of Tokyo Graduate School of Agriculture and Life Sciences)
[3P-595]The mechanism for finely regulating the developmental rate of each organ during the early stages of Drosophila metamorphosis
Mitsuki Ikeda1,2, Yuji Kageyama3, Kazutaka Akgi4, ○Hitoshi Ueda1 (1. Okayama University, 2. Faculty of Natural Science and Technology, Okayama University, 3. Biosignal Research Center, Kobe University, 4. Division of Presymptomatic Disease, Institute of Natural Medicine, University of Toyama)
[3P-596]Elucidation of heterogeneity in smooth muscles development by single-cell RNA sequencing
○Saki Egashira1, Hana Hashiguchi1, Takeru Fujii2, Mako Nakamura3, Yasuyuki Ohkawa2 (1. Kyushu Univ. Graduate School of Bioresource and Bioenvironmental Sciences, 2. Kyushu Univ. Medical Institute of Bioregulation, 3. Kyushu Univ. Center for Promotion of International Education and Research, Faculty of Agriculture)
[3P-597]The role of cadherins in male germ cell differentiation in chickens
○Mashiro Mitsufuji1, Takumi Terada1, Tenkai Watanabe1, Ryo Ezaki1, Yoshiaki Nakamura1, Mei Matsuzaki1, Hiroyuki Horiuchi1,2 (1. Grad. Sch. Int. Sci. Life, Hiroshima Univ., 2. Genome Edit. Innov. Ctr, Hiroshima Univ.)
[3P-598]Di-n-butyl Phthalate Enhances Neural Differentiation of Mouse Embryonic Stem Cells through Neurogenic Differentiation 1 (NeuroD1) Pathway
○CHIA-CHEN KU1, Kenly Wuputra1, Ya-Han Yang1, Ying-Chu Lin1, Kazushige Yokoyama1 (1. Kaohsiung Medical University)
[3P-599]The role of developmental timers driven by synchronized intracellur localization of transcription factors
○Yuichiro Ishiyama1, Ami Goto1, Kensuke Yamashita1, Makoto Kashima2, Tetsuya Muramoto3 (1. Toho University, 2. Toho Univ., 3. Toho University.)
[3P-600]Effects of co-culture with glial cells on neuronal differentiation of mouse iPS cells
○Yuto Sugaya1, Hideo Kawaguchi1 (1. Grad Sch Life Sci,Toyo Univ.)
[3P-601(3AS-15-06)]Evaluation and investigation of the role of the protein histidine methyltransferase CARNMT1 on the differentiation and proliferation of skeletal muscle cells
○Megumi Gowa1,2, Tadahiro Shimazu1, Yoichi Shinkai1,2 (1. RIKEN Cellular Memory Laboratory, 2. Saitama Univ.)
[3P-602]How did the muscle evolve? Exploring the ancestral traits of muscles from the study of comb jellies
○Kurato Mohri1, Minato Miyake1, Hiroshi Watanabe1 (1. Okinawa Institute of Science and Technology)
[3P-603]Unraveling gene regulatory networks in human kidney organoids using single-cell multiomic analysis
○Yasuhiro Yoshimura1,2, Benjamin D. Humphreys2 (1. Chiba Univ., 2. Washington Univ. in St. Louis)
[3P-604]Cell culture from gizzard smooth muscle cell mass
○Yoshimi Kim1, Kimiko Fukuda1 (1. Tokyo Metropol. Univ.)
[3P-605]Single cell multiomics identifies transcription factors driving T cell development in mice
○Diego Diez1, Nouhaila Chabchi1, Anna Karina Kawai Gaona1, Xin Sun1 (1. Osaka University)
[3P-606]SMAD Proteins Regulate the Browning of White Adipocytes
○Ryota Sekine1, Yuki Taguchi2, Daiki Nakatsu3, Rina Kunishige2, Fumi Kano3 (1. School of Life Science and Technology, Institute of Science Tokyo, 2. Institute of Science Tokyo, Institute of Integrated Research, Multimodal Cell Analysis Collaborative Research Cluster , 3. Institute of Science Tokyo, Institute of Integrated Research, Cell Biology Center)
[3P-607]Dynamic changes in G quadruplex structure and its role in muscle differentiation process
○Kohei Takeuchi1, Gessho Masaya1, Yoshiki Hashimoto1, Wataru Sugimoto1, Hideaki Fujita2, Daisuke Miyoshi1, Keiko Kawauchi1 (1. Faculty of frontiers of Innovative Research in Science and Technology (FIRST), Konan University, 2. Department of Stem Cell Biology, Research Institute for Radiation Biology and Medicine, Hiroshima University)
[3P-608(3PS-02-13)]Extracellular extrusion of syntaxin4 and its biological significance in early embryogenesis
○Sae Nozaki1, Yohei Hirai1 (1. Kwansei Gakuin University)
[3P-609(3AS-06-06)]Study on the role of glycosylation in embryogenesis
○Shuang Li1, Chie Naruse 1, Heng Wei 1, Kazushi Sugihara1, Masahide Asano 1 (1. Institute of laboratory animals, graduate school of medicine,kyoto university)
[3P-610(3PS-08-04)]Analysis of mammalian ploidy characteristics using multiple polyploidized mouse embryos.
○Hiroyuki Imai1, Sumito Matsuya2,3, Kaoru Fujino2, Muneyoshi Hyoto1, Kiyoshi Kano2, Takeshi Ken Kusakabe1 (1. Lab. of Vet. Anat., Yamaguchi University, 2. Lab. of Dev. Genet., Yamaguchi University, 3. Lab. of Vet. Anat., Kagoshima University)
[3P-611(3PS-01-06)]The Role of Refee in Proper Stage-Specific Expression and Functionality of Mouse Endogenous Retrovirus L
○Mie Kobayashi-Ishihara1, Akihiko Sakashita1, Hirotsugu Ishizu1, Youjia Guo1, Tomohiro Kitano1, Masaru Ariura1, Hidetoshi Hasuwa1, Kensaku Murano1, Hidetaka Kosako2, Haruhiko Siomi1 (1. Keio University School of Medicine, 2. Division of Cell Signaling, Institute of Advanced Medical Sciences, Tokushima University)
[3P-612]Functional analysis of nuclear F-actin in mouse early embryonic development
○Yasuki Miyagawa1, Yuko Sakamoto2, Akihiro Inoue1, Shuntaro Nishizaki1, Risa Kadono2, Ryunosuke Mori2, Kei Miyamoto1 (1. Kyushu Univ., 2. Kindai Univ.)
[3P-613]P-body appearance depend on mitochondrial reconstruction with cell cycle elongation during MBT in Xenopus embryo
○Shuichi Ueno1, Kazuyoshi Kakutani1 (1. Graduate School of Science and Technology for Innovation, Yamaguchi University)
[3P-614(3AS-06-07)]Development of peri-implantation embryo culture method using endometrial cells
○Miku Fujiwara1, Takenobu Nii1, Chikara Meno1 (1. Kyushu Univ.)
[3P-615]Mechanisms underlying microglial colonization into the developing brain
○HISA ASAI1, Yuki Hattori1 (1. Dept. of Anat. Cell. Biol., Grad. Sch. of Med., Nagoya Univ.)
[3P-616]Study of Gene Regulatory Networks in the Early Developmental Stages of Ascidians Using Machine Learning
○Mei Murata1, Yutaka Satou2, Naoki Osada1, Toshinori Endo1 (1. Hokkaido Univ., 2. Kyoto Univ.)
[3P-617]The mechanisms of Epiblast formation in mice
○Masakazu Hashimoto1,2 (1. Fukushima Med. Univ., 2. Osaka Univ.)
[3P-618]CRISPR-Cas knockout and knockdown analysis of the zebrafish cathepsin Lb gene cluster
○RIKU UMEZONO1, Yusuke Kamachi1 (1. Kochi University of Technology)
[3P-619]One-step generation of Hox gene simultaneously edited mice using transposon-dependent gRNA delivery
○Kasumi Yumoto1, Tomoki Chiba1, Masayasu Sega1,2, Lin Liu1, Takahide Matsushima1, Hiroshi Asahara1 (1. Institute of Science Tokyo System BioMedicine, 2. Institute of Science Tokyo Department of Perinatal And Women's Medicine)
[3P-620]Novel apoptosis-independent quality control mechanisms in mouse pluripotent tissues
○Rui Shibata1, Masakazu Hashimoto2, Hiroshi Sasaki1 (1. Osaka Univ.,FBS, 2. Fukushima Med.Univ.,Cell Sci.)
[3P-621]Mechanisms of the size regulation in early post-implantation mouse embryos
○Daisuke Masui1, Masakazu Hashimoto2, Masanori Uchikawa1, Hiroshi Sasaki1 (1. Osaka University, 2. Fukushima Medical University)
[3P-623(3AS-17-08)]Specific molecular regulation of centrioles during spermatogenesis
○Yutaka Takeda1, Nena Stojanović2, Hiroki Shibuya1,2 (1. RIKEN BDR, 2. University of Gothenburg)
[3P-624]Resistance of human endometrium to ferroptosis
○Susumu Tanaka1, Ayaka Tanaka1, Kotoha Takaki1, Miyu Yazawa1, Namika Yoshida1 (1. University of Nagasaki, Siebold)
[3P-625]Analysis of a Sox9 enhancer modified mouse
○Mito Yasuhara1,2, Yumiko Azuma1, Atsumi Tsuji-Hosokawa1,3, Momoka Kasugai1, Mika Hirabayashi1, Miho Terao1, Shuji Takada1,2 (1. Dept. of Systems BioMed., NCCHD, 2. Dept. NCCHD, Grad. Sch. Med. Dent. Sci., TMDU, 3. Dept. Dev. Biol. Pediatr, Grad. Sch. Med. Dent. Sci., TMDU)
[3P-626]Functional analysis of the C. elegans serine protease gene try-7 during male germline functions
○Ayano Matsuo1, Kazuki Hashimoto1, Yoshihiro Shimada1, Hitoshi Nishimura1 (1. Dept. Lif. Sci., Fac. Sci. Eng., Setsunan Univ.)
[3P-627]Uterine-specific KMT2D knockout mice are infertile due to implantation failure
○Ryosuke Kobayashi1,2, Yuki Tajika3, Junki Kohmaru2, Sumiyo Morita2, Takuro Horii2, Yoichi Mizukami4, Shizu Aikawa5, Yasushi Hirota5, Izuho Hatada2 (1. Lab. of Vet. Anatomy, Rakuno Gakuen Univ., 2. Lab of Genome Sci., IMCR, Gunma Univ., 3. Gunma Prefecture College of Health Sci., 4. Sci. Res. Center, Yamaguchi Univ., 5. Dep. of Obst. Gynecol, The Univ. of Tokyo)
[3P-628]Mapping of functional sequences on mouse Amh promoter by in vivo genome editing
○Iku Tsuchiya1,2, Miho Terao1, Sizuka Kirino3, Kenichi Kashimada3, Atsumi Tsuji-Hosokawa1,3, Shuji Takada1,2 (1. Dept. of Systems BioMed., NCCHD, 2. Dept. of NCCHD, Grad. Sch. of Med. and Dent. Sci., TMDU, 3. Dept. of Ped. and Dev. Biol., Grad. Sch. of Med. and Dent. Sci., TMDU)
[3P-629]The C. elegans gene nsun-2, encoding tRNA methyltransferase, acts during temperature-sensitive spermatogenesis.
○Yoshihiro Shimada1, Ayaka Yoshida1, Nana Kanazawa1, Yukiko Karuo2, Masaaki Omote2, Hitoshi Nishimura1 (1. Dept. Lif. Sci., Fac. Sci. Eng., Setsunan Univ., 2. Fac. Pharm. Sci., Setsunan Univ.)
[3P-630]HDA-2/HDAC3 transgenerationally regulates embryonic development and fertilized egg size control through CED-12 in C. elegans
○Roku Arima1, Takuma Unno1, Hisashi Takatsuka1, Fangzheng Li1, Yukihiko Kubota2, Masahiro Ito1 (1. Graduate School of Life Sciences, Ritsumeikan University, 2. College of Life Sciences, Ritsumeikan University)
[3P-631]Generation of knock-in pigs using AAV vectors for conditional ablation
○Mitsuhiro Noguchi1, Fuminori Tanihara1, Yuka Inage2, Hiromasa Hara1, Makoto Inoue1,3, Yutaka Hanazono1, Takashi Yokoo2, Arata Honda1 (1. Jichi Medical Univ., 2. Jikei Medical Univ., 3. Sumitomo Phama Co., Ltd)
[3P-632]Improvement of a protocol for refrigerated storage of mouse epididymis
○Tomohide Imada1, Saki Uehara1, Atsuko Kageyama2, Yui Kawata2, Junya Ito1,2, Naomi Kashiwazaki1,2 (1. Laboratory of Animal Reproduction, Graduate School of Veterinary Sciences, Azabu University, 2. School of Veterinary Medicine, Azabu University)
[3P-633]Analysis of Heterochromatin protein 6-mediated transposable element repression in Drosophila ovaries under heat stress
○Junki Watanabe1, Hayato Okumura2, Mika Toyoda2, Hideki Yoshida3, Masanori Mukai1,2 (1. Grad. Sch. of Nat. Sci., Konan Univ., 2. Dept. of. Biol., Fac. of Sci. Eng., Konan Univ., 3. Dept. of Appl. Biol., Kyoto Inst. of Tech.)
[3P-634]MEIOSIN has an intrinsic capability to activate meiotic program without STRA8
○Ryuki Shimada1, Yukiko Imai2, Toshihiro Kawasaki2, Shigehiro Kuraku2, Noriyoshi Sakai2, Kei-ichiro Ishiguro1 (1. IMEG, Kumamoto Univ., 2. NIG)
[3P-635]The analysis of Ccdc201, female-specific meiotic chromosome associated protein; Elucidating oocyte aging
○Sakie Iisaka1, Ryuki Shimada1, Kimi Araki2, Kei-ichiro Ishiguro1 (1. IMEG, Kumamoto Univ., 2. IRDA, Kumamoto Univ.)
[3P-636]Visualization and maturation of PGC-like cells derived from male rat ES cells
○Hiroki Kojima1, Mami Oikawa1, Tomoyuki Yamaguchi1, Toshihiro Kobayashi2 (1. Tokyo University of Pharmacy and Life Sciences, 2. Tokyo University)
[3P-637]Effect of resveratrol on endometrial mitochondria and fertility in cows
○Ibuki Matsufuji1, Satoshi Kato2, Sho Nakamura1, Satoshi Ohkura1, Yuji Kimura3, Shuichi Matsuyama1 (1. Nagoya University School of Agricultural Sciences Graduate School of Bioagricultural Sciences, 2. Gunma Prefecture Livestock Experiment Station, 3. Graduate School of Environmental, Life, Natural Science and Technology, Okayama University)
[3P-639]Roles of Importin13 in mouse germ cell development
Yasuka L Yamaguchi1, Patrick PL Tam2, Hiroshi Kiyonari3, ○Satomi S Tanaka1 (1. Kumamoto Health Sci. Univ., 2. CMRI, Univ. of Sydney, 3. RIKEN BDR)
[3P-640]Development of germline markers and analysis of germ cells under exposure to endocrine disrupting chemicals (EDCs) using quail embryos
○Yuya Ogawa1, Shusei Mizushima1, Asato Kuroiwa1 (1. Hokkaido Univ.)
[3P-641]Mitochondrial DNA biogenesis in growing mouse oocytes
○Son Quang Do1, Hiroaki Funahashi1, Takuya Wakai1 (1. Okayama University, Graduate School of Environmental, Life, Natural Science and Technology)
[3P-642]Role of Derlin family-mediated endoplasmic reticulum proteostasis in spermatogenesis.
○Naoya Murao1, Hideki Nishitoh1 (1. Laboratory of Biochemistry and Molecular Biology, Department of Medical Sciences, University of Miyazaki)
[3P-643]Elucidation of the mechanism that ensures quality of gamete by germ cell intercellular bridge (ICB)-related factors
○Tokuko Iwamori1, Yuzuru Kato2, Hiroyuki Imai3, Seiji Takashima4, Naoki Iwamori5 (1. Nakamura Gakuen University, 2. Osaka University, 3. Yamaguchi University, 4. Shinshu University, 5. Kyushu University)
[3P-644]The germ cell-specific heat shock transcription factor HSF5 drives spermatogenesis-specific gene expression by establishing chromatin accessibility
○Yusuke Osato1, Keigo Araki1, Yuka Karato1, Tatsuya Hattori1, Masatoshi Ooga2, Rei Inoue2, Teruhiko Wakayama2, Satoshi Namekawa3, Kai Otsuka1, So Maezawa1 (1. Tokyo Univ. of Sci., 2. Univ. of Yamanashi, 3. UC Davis)
[3P-645]TdIF1 is required for the progression of meiotic prophase during mouse spermatogenesis
○Yuto Yamada1, Kai Otsuka1, Yusuke Osato1, Hisao Masai, Tomohiro Iguchi, Satoshi Namekawa, So Maezawa1 (1. Tokyo Univ. of Sci.)
[3P-646]Evaluation of differentiation potentials of F1 hybrid ES cell lines established by crossing mice belonging to different subspecies, utilizing embryoid body formation
○Masaki Ota1, Ayaka Saito1, Hidenori Kiyosawa1 (1. Lab. for Genomic Sci., Dept. of Life Sci., ChibaTech.)
[3P-647]Verification of differentiation potential in mouse F1 hybrid ES cells with different genetic background
○Ayaka Saito1, Hidemasa Kato2, Hidenori Kiyosawa1 (1. Lab. for Genomic Sci., Dept. of Life Sci., ChibaTech., 2. Dpt. Dev. Biol. and Funct. Genom., Grad. Sch. of Med., Ehime Univ.)
[3P-648]Functional analysis of the repeat region CSCT in the mouse genome
○Kumiko Yoshinobu1, Takumi Yonemori1, Toyoyuki Toyoda2, Masatake Araki1, Kimi Araki1 (1. IRDA, Kumamoto Univ., 2. RIKEN BRC, IBID)
[3P-649]Transcription Factor-Induced Cell Fate Conversion in Somatic Cells and Associated Epigenomic Alterations
○Kenichi Horisawa1, Atsushi Suzuki1 (1. Kyushu University)
[3P-650]Genetic engineering approach to reveal the mechanisms of mouse testicular teratoma development.
○Arisa Nagashima1, Atsushi Suzuki1 (1. Yokohama National Univ.)
[3P-651]Application of the RNAi method using simple siRNA synthesis to early amphibian embryos
○Minoru WATANABE1,2,3, Miki SAKURAI2, Ruku MORISITA2, Yuta TAGAMI3, Takeshi NISHIYAMA3, Michiko OMOTE3 (1. Tokushima University, Institute of Liberal Arts and Sciences, 2. Tokushima University, Faculty of Science and Technology, 3. Tokushima University, Faculty of Integrated Arts and Sciences)
[3P-652]NSD1 heterozygosity reduces neonatal survival in mice
○Musashi Ichimaru-Kubiura1, Satoshi Hara1, Hitomi Yatsuki1, Hidenobu Soejima1 (1. Saga University)
[3P-653]Development and genomics of Pacific saury Cololabis saira
○Rie Kusakabe1, Ryo Kinoshita1, Shinya Yamauchi2, Shigehiro Kuraku3 (1. Kansai University, 2. Aquamarine Fukushima, 3. NIG)
[3P-654]Generation of transgenic nude mice for xenogeneic spermatogonial transplantation
○Kazue Kakiuchi1, Hiroshi Kubota1 (1. Kitasato Univ.)
[3P-655]Novel Spiroplasma Identification and Involvement in Male-Killing in a Wild Population of Lymantria dispar
○Kyoko Ishida1, Masataka Suzuki1, Maki Inoue2, Daisuke Kageyama3, Keigo Kurihara4 (1. Graduate School of Frontier Sciences The University of Tokyo, 2. Department of Applied Biological Science, Tokyo University of Agriculture and Technology, 3. Insect Microbe Research Unit, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, 4. NEXCO Engineering Hokkaido)
[3P-656(3MS-05-04)]Bidirectional interaction between gut microbes and the host under artificial hibernation
○Reina Miyajima1, Takahiro Yamada2, Genshiro Sunagawa3, Takeshi Sakurai4, Koji Hase1 (1. Division of Biochemistry, Graduate school of Pharmaceutical Science, Keio University, Tokyo, Japan, 2. Department of Immunology, Yale School of Medicine, 3. Laboratory for Hibernation Biology, RIKEN Center for Biosystems Dynamics Research, 4. Faculty of Medicine, University of Tsukuba)
[3P-657]Time-series analysis of gut microbiome in EAE model mouse provides a new perspective
○Hiroaki Masuoka1, Rina Kurokawa1, Ben JE Raveney2, Daiki Takewaki2, Lena Takayasu1, Rie Maskawa3, Yu Yoshikawa3, Tanzila Islam3, Hideki Takayasu3, Misako Takayasu3, Wataru Suda1 (1. RIKEN IMS, 2. NCNP, 3. Institute of Science Tokyo)
[3P-658]Evaluation of the anti-obesity effect of Christensenella minuta feeding using Caenorhabditis elegans
○Kanamu Chikuba1, Takayuki Wada1, Yoshihiko Tanimoto1,2, Eriko Kage Nakadai1,2 (1. Osaka Metropolitan Univ., 2. Kyoto Univ.)
[3P-659]Pathogenic mechanism analysis of enterotoxigenic Escherichia coli using Caenorhabditis elegans as an alternative model host.
○Chinatsu Yamamura1, Anri Matsuda1, Takayuki Wada1, Yoshihiko Tanimoto1,2, Eriko Nakadai1,2 (1. Osaka Metropolitan Univ., 2. Kyoto univ.)
[3P-660]Gene Ontology Estimation from Amplicon Analysis Data of Intestinal Microbiota
○Kazuki Arita1, Yoshio Nakano1, Kazumi Yoshizawa1, Satoru Miyazaki1 (1. Tokyo Univ of Sci.)
[3P-661]Sexual dimorphism and post-mating changes in cricket gut microbiome using metagenomic shotgun analysis
○Kazuya Hirata1, Masahito Hosokawa1, Takeshi Suzuki2, Kei Yura1,3, Toru Asahi1,4, Kosuke Kataoka4,5 (1. Dept. of Adv. Sci. Eng., Grad. Sch. of Adv. Sci. Eng., Waseda Univ., 2. Grad. Sch. Bio-App. and Sys. Eng., Tokyo Univ. Agric. Tech., 3. Grad. Sch. Hum. Sci., Ochanomizu Univ., 4. Dept. of Comp. Res. Org., Waseda Univ., 5. Grad. Sch. Eng., Tokyo Univ. Agric. Tech.)
[3P-662]Evidence of Efficient Polypropylene Biodegradation by Bacillus cereus Isolated from Waxworms' Gut (Galleria mellonella Larvae)
○Indra Nyamjav1,2, Sukkyoo Lee1,2 (1. Daegu Gyeongbuk Institute of Science&Technology (DGIST), 2. Department of Brain Sciences)
[3P-663]Screening of natural compounds with sleep control effects using hydra
○Asa Kimoto1, Taichi Itoh1,2 (1. Kyushu Univ., 2. Kyushu Univ)
[3P-664]The mechanism of the synchronized Hes7 oscillations in the mouse presomitic mesoderm-like in vitro tissue
○Ayumi Goto1, Xueqi Jia1, Akihiro Isomura1, Ryoichiro Kageyama1 (1. RIKEN)
[3P-665]Construction of a CRISPR/Cas9-Induced Single-cell Bioluminescence Reporter System in Individual Plants and Its Characterization
○Ryohei Ueno1, Shogo Ito1, Tokitaka Oyama1 (1. Division of biological science, Graduate School of Science, Kyoto University)
[3P-666]Effect of Cannabidiol on Circadian Clock Rhythm in PER2::LUCIFERASE Mouse Embryonic Fibroblast
○HSIAOHSIEH WANG1, Toru ASAHI1,2,3, Chihiro NOZAKI1,4 (1. Graduate School of Life Science and Medical Bioscience, School of Advanced Science and Engineering, Waseda University, 2. Comprehensive Research Organization, Waseda University, 3. Research Organization for Nano & Life Innovation, Waseda University, 4. Global Center for Science and Engineering, Waseda University)
[3P-667]Mechanisms of mTOR signaling regulation dependent on neuronal cell adhesion
○Koichi Hashizume1, Yoneko Hayase1, Shigehiro Ogata1, Yukiko Ueno-Inoue1, Takayoshi Inoue1, Yu-ichi Goto1, Shinichiro Taya2, Mikio Hoshino1 (1. NCNP, 2. Fujita Health Univ.)
[3P-668]Extracellular matrix remodeling by microglia regulates synapse plasticity in zebrafish hindbrain
○Haruna Nakajo1, Nicholas Silva1, Sunny Mula1, Anna Molofsky1 (1. University of California, San Francisco)
[3P-669]Ninein splicing reporters to visualize neuronal differentiation
○Taisei Aoki1, Kensuke Hayashi1 (1. Sophia University)
[3P-670]Expression analysis of histone H4c cluster genes in the developing mammalian cerebral cortex.
○Haruna Nagasawa1, Kaneyasu Nishimura2, Sota Ikeda1, Tadashi Nomura1 (1. Applied Biology, Kyoto Institute of Technology, 2. Graduate School of Brain Science, Doshisha University)
[3P-671]Observation of the aggregation process of amyloid β dynamics by time-resolved X-ray imaging
○Kotaro Ozaki1, Yoriko Sonoda2, Tomoyo Ochiishi2, Kazuaki Yoshimura3, Masahiro Kuramochi1 (1. Ibaraki Univ., 2. AIST, 3. Nihon Univ.)
[3P-672]Differential neurogenic patterns underlie the formation of primary and secondary areas in the developing somatosensory cortex
○Naoto Ohte1, Carina Hanashima2 (1. Department of Integrative Bioscience and Biomedical Engineering, Graduate School of Advanced Science and Engineering, Waseda University, 2. Faculty of Education and Integrated Arts and Sciences, School of Education, Waseda University)
[3P-673]A DNA demethylation-related gene TDG is upregulated by human-specific non-coding RNA to be involved in the expansion of neural stem cell pools
○Shota Zenno1, Sota NISHIDA2, Boyang AN2, Mizuki HONDA1,2, Fumihiro MORISHITA1,2, Takuya IMAMURA1,2 (1. Dept of Biological Sci, Hiroshima Univ., 2. Grad Sch of Integrated Sci for Life, Hiroshima Univ.)
[3P-674]Role for Protogenin in the Regulation of Human Neural Stem Cells and Search for Regulators of Its Expression
○Naoyuki Kishida1, Boyang An1, Hiroto Akuta1, Sota Nishida1, Fumihiro Morishita1, Takuya Imamura1 (1. Graduate School of Integrated Sciences for Life)
[3P-675]Effects of suppression of subplate neuron activity on brain formation in the developing cortex
○Haruka Nomura1,2, Yasuhiro Matsumura2, Keiko Moriya2, Rumi Kondo1, Chiaki Maruyama2 (1. Life Sciences, Graduate School of Ochanomizu University, 2. Developmental Neuroscience Project ,Tokyo Metropolitan Institute of Medical Science)
[3P-676]Cellular mechanisms underlying cross-modal plasticity in the absence of visual inputs.
○Hayato Saito1, Carina Hanashima2 (1. Department of Integrative Bioscience and Biomedical Engineering, Graduate School of Advanced Science and Engineering, Waseda University, 2. Faculty of Education and Integrated Atrs and Sciences, School of Education, Waseda University)
[3P-677]Vitamin C uptake in neural progenitor cells regulates active DNA demethylation during neurogenesis
○Saya Mizuno1, Rui Sakaki1, Hiroki Mabuchi1, Akira Kamiyoshi1, Mayumi Higuchi1, Fumihito Miura2, Hiromitsu Araki3, Kimi Araki4, Takeshi Yagi1, Noriyuki Sugo1 (1. Graduate School of Frontier Biosciences, Osaka University,, 2. Kyushu University Graduate School of Medical Sciences, 3. Kyushu University Graduate School of Economics, 4. Institute of Resource Development and Analysis, Kumamoto University)
[3P-678]Deciphering neurogenic patterns governing the segregation of neocortical deep-layer neuron subtypes
○Shoko Yoshizawa1, Carina Hanashima2 (1. Department of Integrative Bioscience and Biomedical Engineering, Graduate School of Advanced Science and Engineering, Waseda University, 2. Faculty of Education and Integrated Arts and Sciences, School of Education, Waseda University)
[3P-679]Analysis of Thsd7a expression dynamics in embryonic and postnatal developing mouse brain
○Rikuto Sato1, Naoto Oote1, PeiShan Hou1, Carina Hanashima2 (1. Department of Integrative Bioscience and Biomedical Engineering, Graduate School of Advanced Science and Engineering, Waseda University, 2. Faculty of Education and Integrated Arts and Sciences, School of Education, Waseda University)
[3P-680]Diversity and distribution of extraocular opsins in the ascidian Ciona intestinalis type A
○Iori Den1, Tatsuki Mizojiri1, Ayana Maruo1, Nanako Okawa1, Fuki Gyoja1, Keiichi Kojima2, Takahiro Yamashita3, Yoshinori Shichida3,4, Xin Zeng5,6, Yutaka Suzuki5, Kenta Nakai6, Takehiro Great Kusakabe1 (1. Dept. of Biol., Fac. of Sci. & Engineer., Konan Univ., 2. Grad. Sch. of Med. Dent. Pharm. Sci., Okayama Univ., 3. Grad. Sch. of Sci., Kyoto Univ., 4. Res. Org. for Sci. and Tech, Ritsumeikan Univ., 5. Grad. Sch. of Front. Sci.,Univ. of Tokyo, 6. Inst. of Med. Sci., Univ. of Tokyo)
[3P-681]Cryo-EM Single-Particle Analysis of the BRS-3 Signaling Complex Regulating Feeding and Metabolism
○Akitoshi Inoue1, Tomoyo Takai1, Mika Hirose2, Chiyo Suno1, Takayuki Kato2, Ryoji Suno1, Takuya Kobayashi1 (1. Kansai Medical University, 2. Institute for Protein Research, Osaka University)
[3P-682]Sex Differences in Survival and Differentiation of Primary Culture Oligodendrocytes
○Hitomi Misawa1, Yuichi Hiraoka2, Nobuharu Suzuki1 (1. Department of Clinical Bioanalysis and Molecular Biology, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University , 2. Laboratory of Animal Resources, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo)
[3P-683]Function of vasopressin expressed in the mouse olfactory system
○Hirofumi Nishizumi1 (1. University of Fukui)
[3P-684]Roles of astrocytic and neuronal cell adhesion molecules in the formation and regulation of excitatory tripartite synapses
○Muneaki Miyata1,2, Osamu Nozawa2, Hajime Shiotani1,2, Takeshi Kameyama2, Ryouhei Komaki2, Tatsuhiro Shimizu2, Toshihiko Kuriu3,4, Yutaro Kashiwagi5, Yuka Sato5, Shigeo Okabe5, Yoshimi Takai2, Kiyohito Mizutani1,2 (1. Tokushima University, 2. Kobe University, 3. Osaka Medical and Pharmaceutical University, 4. Osaka Medical and Pharmaceutical University Hospital, 5. The University of Tokyo)
[3P-685]Association between high social behavior and brain function in mice selectively bred for active tameness
○Bharathi Venkatachalam1,2, Mao Nemoto3,4, Yasushi Shimoda3,4, Tsuyoshi Koide1,2 (1. National Institute of Genetics , 2. The Graduate University for Advanced Studies, SOKENDAI, 3. Department of Materials Science and Bioengineering, 4. Nagaoka University of Technology)
[3P-686]Increased tameness shown by the gut bacterium, Limosilactobacillus reuteri, in domesticated mice
○Tsuyoshi Koide1,2, Bhim B Biswa1,2 (1. National Institute of Genetics, 2. SOKENDAI)
[3P-687]Morphological and behavioral study of mice carrying a mutation in the guanosine diphosphate mannose 4,6-dehydratase (Gmds) gene
○Abdullah Syafiq Edyanto1,2, Yuji Imai1, Akiteru Maeno3, Yasuhiro Utsuno4, Satoko Miyatake4,5, Naomichi Matsumoto4,5,6, Tsuyoshi Koide1,2 (1. Mouse Genomics Resource Laboratory, National Institute of Genetics, Mishima, Shizuoka, Japan, 2. Graduate Institute for Advanced Studies, SOKENDAI, Mishima, Shizuoka, Japan, 3. Cell Architecture Laboratory, National Institute of Genetics, Mishima, Shizuoka, Japan, 4. Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan, 5. Department of Clinical Genetics, Yokohama City University Hospital, Yokohama, Kanagawa, Japan, 6. Department of Rare Disease Genomics, Yokohama City University Hospital, Yokohama, Kanagawa, Japan)
[3P-688]Analysis of brain structure and behavior in a novel Topoisomerase IIβmutant mouse
○Xianghe Song1,2, Yumiko Hatanaka2, Hiroyuki Sasanuma3, Hideya Kawaji4, Kimiko Fukuda1, Chiaki Ohtaka Maruyama1,2 (1. Development Biology, Graduate School of Science Department of Biological Sciences, Tokyo Metropolitan University, 2. Developmental Neuroscience Project, Tokyo Metropolitan Institute of Medical Science, 3. Genome Dynamics Project, The Tokyo Metropolitan Institute of Medical Science, 4. Research Center for Genome & Medical Sciences, The Tokyo Metropolitan Institute of Medical Science)
[3P-689]A neural activity-induced gene Hr38 regulates the long-term courtship memory in dopamine neurons of Drosophila melanogaster
○Aya Nishikawa1, Seika Kiya1, Taketoshi Kiya1 (1. Div. of Life Sci., Grad. Sch. of Nat. Sci & Tech., Kanazawa Univ.)
[3P-690]The studies on the mechanisms controlling ultradian rhythms in Planarians
○Natsuki Hayashi1, Maria Narahashi1, Kiyokazu Agata2, Satoshi Matsuo1, Takeshi Inoue1 (1. Tottori Univ., 2. NIBB)
[3P-691]Octopamine in clock neurons modulates consolidation and maintenance of long-term memory in Drosophila
○Yuto Kurata Kurata1, Takaomi Sakai1 (1. Tokyo Metropolitan University)
[3P-692]Evaluation of the Effect of Antifreeze Proteins on the Olfactory Adaptation of the C. elegans After Cryopreservation
○Ayano Kawamura1, Masahiro Kuramochi1 (1. Department of Materials Science and Engineering, College of Engineering, Ibaraki University)
[3P-693]Pdf receptor is essential for long-term memory maintenance in Drosophila
○Rei Shirakawa1, Sho Inami2, Takaomi Sakai1 (1. Tokyo Metropolitan University, 2. Thomas Jefferson University)
[3P-694]Effects of aging on forgetting in C. elegans.
○Aiko Nakazono1, Yuki Onishi1, Takeshi Ishihara1,2 (1. Graduate School of Systems Life Sciences, Kyushu University, 2. Department of Biology, Faculty of Science, Kyushu University)
[3P-695]Social experience impacts the translatome patterns in courtship triggering P1 neurons of Drosophila males
○Akari Kabasawa1,2, Daniel J Rindner2, Kenta Tomihara2, Yusuke Hara2, Daisuke Yamamoto2, Kosei Sato1,2 (1. University of Hyogo Graduate School, 2. National Institute of Information and Communications Technology (NICT))
[3P-696(3PS-16-03)]Functional analysis of ZBTB16 mutation in autism spectrum disorder
○Miyuki Doi1,2, Noriyoshi Usui1,2,3,4, Saki Ishino3, Nanako Nakama1, Yuki Fujiwara4, Taiichi Katayama4, Shoichi Shimada1,2,4 (1. Dept Neurosci Cell Biol, Grad Sch Med, Osaka Univ, 2. Addiction Res Unit, Osaka Psych Res Center, Osaka Psych Med Cent, 3. COC, Grad Sch Med, Osaka Univ, 4. United Grad Sch Child Dev, Osaka Univ)
[3P-697]Relationship between excitatory neuron synaptic potentiation and SIK3 signaling pathway to induce NREM sleep
○Motoki Juichi1, Yusuke Iino1, Miyo Kakizaki1, Shinnosuke Nomura1,2, Shinya Nakata1, Takeshi Sawada1,2, Haruo Kasai2, Hiromasa Funato1,3, Shoi Shi1, Masashi Yanagisawa1 (1. University of Tsukuba, 2. University of Tokyo, 3. Toho University)
[3P-698]Locomotor restriction stress in Drosophila suppresses male courtship activity via activation of dopamine signaling
○Tomohito Sato1, Takaomi Sakai1 (1. Tokyo Metropolitan University)
[3P-699]The Effect of Interneurons on Neural Circuit Function in C.elegans
○ryuto sakuno1, yukiharu aoki1, yu toyosima2, ryo yosida3, yuiti iino2, takesi isihara4 (1. Graduate School of Systems Life Sciences Kyushu University, 2. School of sciences The university of Tokyo, 3. The Institute of Statistical Mathematics, 4. Faculty of sciences Kyushu University)
[3P-700]Screening of novel sleep-promoting agents using larval zebrafish
○Yoshito Hosokawa1, Takaya Suganuma1, Shun Kubo1, Yoshihiko Minegishi1, Takuya Mori1 (1. Kao corporation)
[3P-701]The relationship between decreased social interaction behavior and blood cells after psychological stress using machine learning
○Ousuke Mizuno1, Emiko Kasahara1, Yuina Nishikawa1, Takumi Sakamoto1, Kodai Suzue1, Mizuki Kobayashi1, Riko Okayama1, Yuma Yoinara1, Mika Hori1, Atsuo Sekiyama1,2 (1. Osaka Univ., 2. Shiga Univ. Med. Sci.)
[3P-702]Self- and meta-recognition-dependent vulnerability of attractiveness in male mice.
○Yoshinori Ñ Ohnishi1, Yukie Kawahara1, Yoko H Ohnishi1, Akinori Nishi1 (1. Kurume Univ. School of Medicine)
[3P-703]Analysis of the regulatory mechanism of CD11c-positive microglia induction by the membrane protein SIRPα
○Yuka Moriya1, Etsumi Oike1, Shunya Hanzawa1, Yuka Nakamaru1, Eiko Matsumoto1, Eriko Urano1, Ryosuke Kobayashi2, Takuro Horii2, Izuho Hatada2, Yuriko Hayashi3, Takashi Matozaki4, Hiroshi Ohnishi1 (1. Dept Lab Sci, Gunma Univ Grad Sch Health Sci, Gunma, Japan, 2. Biosignal Genome Resource Center, IMCR, Gunma Univ, Gunma, Japan, 3. Dept Health Sci, Gunma PAZ Univ Grad Sch Health Sci, Gunma, Japan, 4. Div Biosig Reg, Dept Biochem Mol Biol, Kobe Univ Grad Sch Med, Kobe, Japan)
[3P-704]Analysis of age-dependent effects of receptor-type molecule SIRPα deficiency on microglia activation in mice
○Shunya Hanzawa1, Etsumi Oike1, Yuka Moriya1, Takuro Honzawa1, Eiko Matsumoto1, Eriko Urano1, Yuriko Hayashi2, Takashi Matozaki3, Hiroshi Ohnishi1 (1. Dept Lab sci, Gunma Univ Grad Sch Health Sci, Gunma, Japan, 2. Dept Health Sci, Gunma PAZ Univ Grad Sch Health Sci, Gunma,Japan, 3. Div Biosig Reg, Dept Biochem Mol Biol, Kobe Univ Grad Sch Med, Kobe, Japan)
[3P-705]Neuronal conversion from microglia ameliorates impaired neuronal function in mice with chronic ischemic injury
○Takashi IRIE1,2, Taito MATSUDA2, Takahiro MASUDA3, Noriko ISOBE1, Kinichi NAKASHIMA2 (1. Neurology, Kyushu Univ., 2. Stem Cell Biology and Medicine, Kyushu Univ., 3. Molecular Neuroimmunology, Kyushu Univ.)
[3P-706]Identification of a Cerebral Vascular Endothelial Cell Cluster that Increases with Age and Decreases with ARB Treatment
○Sho Kitahara1, Taisuke Kato2, Sachiko Hirokawa2, Kazuki Tainaka3, Osamu Onodera1,2 (1. Department of Neurology, Brain Research Institute, Niigata University, 2. Department of Molecular Neuroscience, Brain Research Institute, Niigata University, 3. Department of System Pathology for Neurological Disorders, Brain Research Institute, Niigata University)
[3P-707]Mitochondrial manipulation regulates inflammation by cGAS-STING pathway and NLRP3 inflammasome, and proposes novel therapy for Gaucher Disease.
○Yoshiyasu Tongu Tongu1, Tomoko Kasahara1, Daisuke Saigusa2, Chikahiko Numakura3, Tomoyoshi Soga4, Kei Murayama5, Takafumi Toyohara6, Takaaki Abe1 (1. Department of Clinical Biology and Hormonal Regulation, Tohoku University Graduate School of Medicine, 2. Laboratory of Biomedical and Analytical Sciences, Faculty of Pharma-Science, Teikyo University, 3. Department of Pediatrics, Yamagata University Graduate School of Medicine, 4. 5.Institute for Advanced Biosciences, Keio University, 5. Diagnostics and Therapeutics of Intractable Disease, Intractable Disease Research Center and Department of Pediatrics, Juntendo University Faculty of Medicine, 6. Department of Nephrology, Tohoku University Graduate School of Medicine)
[3P-708]Xenium in situ analysis of early events in Japanese encephalitis virus brain invasion
○Yasuko Orba1,2,3, Yukie Kashima4, Koshiro Tabata2, Yukari Itakura2, Hirofumi Sawa2,3, Michihito Sasaki1,2, Yutaka Suzuki4 (1. Hokkaido Univ. IIZC, 2. Hokkaido Univ. IVReD, 3. Hokkaido Univ. OHRC, 4. Tokyo Univ. GSFS)
[3P-709]Analysis of the seeding effect of site-specific D-Asp-containing amyloid β
○Takuya Murata1, Naoko Utsunomiya-Tate1 (1. Teikyo Univ.)
[3P-710]Effects of extracellular tau on receptors responsible for inhibitory neurotransmission and their scaffold proteins.
○Miyu Enomoto1, Yoshiyuki Soeda2, Akihiko Takashima2, Shigeo Sakuragi3, Hiroko Bannai3 (1. Dept. of Elec.Eng. Biosci.,Grad.Sch.of Adv.Sci.Eng.,Waseda Univ., 2. Fac. of Sci., Gakushuin Univ., 3. Fac. of Sci. Eng., Waseda Univ.)
[3P-711]Investigation of influencing factors leading to astrocyte-associated diseases in the cerebral cortex
○Makoto Motono1, Yoichi Kondo1 (1. Osaka Medical and Pharmaceutical University)
[3P-712]The effect of extracellular Chromogranin B on the survival of oligodendrocyte lineage cells
○Nanako Yamada1, Momona Yamada1, Reina Oono1, Nobuharu Suzuki1 (1. Grad Sch of Med and Dent Sci, TMDU)
[3P-713]Elucidating the relationship between hibernation and depression
○RISA KAKIMOTO1, Genshiro A. sunagawa1 (1. RIKEN)
[3P-714]Developing an AI for designing blood-brain barrier-penetrating peptides for the treatment of neurological disorders
○Yuto HAKATA1,2, Yuki Otani1,2, Hirofumi Aso2, Daisuke Koga2, Hideyuki Shimizu1,2 (1. Dept. AI Systems Medicine, DSC, Tokyo Med. Dent. Univ., 2. Grad. Sch., Med. Dent. Sci., Tokyo Med. Dent. Univ.)
[3P-715]Analysis of cells in which non-glycosylated mutation of Seipin, a protein responsible for the motor neuron disease Seipinopathy, is knocked in
○Kurosu Kotaro1, Saito Shunsuke2, Sakuma Tetsushi3, Mori Kazutoshi2 (1. Department of Biophysics, Faculty of Science, Kyoto University, 2. Kyoto university Institute for Advanced Study, KUIAS, 3. Graduate School of Agriculture, Kyoto-University)
[3P-716]Analysis of the Phenotypic Link between Amyotrophic Lateral Sclerosis (ALS) and Insulin/IGF-1 Signaling (IIS) Pathway in the C. elegans ALS Model
○Min Soo Shin1,2, Kazuki Ozawa1,2, Motomichi Doi1,2, Shinkai Yoichi1 (1. National Institute of Advanced Industrial Science and Technology, Japan, 2. University of Tsukuba, Graduate School of Science and Technology, Japan)
[3P-717(3PS-16-05)]MECP2-mutant marmosets exhibit primate-specific phenotypes of Rett syndrome
○Noriyuki Kishi1,2, Junko Okahara2, Kenya Sato3, Daisuke Yoshimaru2,4, Yoko Kurotaki3, Kohei Onishi2, Tsukasa Sanosaka1, Rachel Henry5, Taeko Ito1,2, Misako Okuno2, Edward J. Weinstein5, Jill R. Crittenden6, Hirotaka James Okano4, Jun-ichi Hata2,7, Jun Kohyama1, Erika Sasaki3, Tomomi Shimogori2, Hideyuki Okano1,2 (1. Keio Univ., 2. RIKEN CBS, 3. CIEA, 4. Jikei Univ. Med, 5. Horizon Discovery, 6. MIT, 7. Tokyo Metropolitan Univ.)
[3P-718]Effects of triterpenes originating from Onji on the social interaction on the zebrafish
○Sayaka Tateno1, Yuko Futagami2, Ryuji Ryuji3, Akio Inui4, Kazuhiro Shiozaki2 (1. Grad. Sch. Agricult. Forest. Fish., Kagoshima Univ., 2. Fac. Fish., Kagoshima Univ., 3. Kampo Res. Lab., Kracie Ltd., 4. Grad. Sch. Med. Dent. Sci., Kagoshima Univ.)
[3P-719]The relationship between α-synuclein and serotonin in the enteric nervous system
○Yuri Yamada1, Tatsunori Maekawa1, Rei Kawashima1, Shun Tamaki1, Takahumi Ichikawa1 (1. Dept. of Regulation Biochem., Grad. Sch. of Med. Sci., Univ. of Kitasato)
[3P-720]Mass Spectrometry Imaging Revealed the Molecular Alterations by Cuprizone Induced Demyelination
○Ryoma Kizu1, Shinji Yamamoto2, Ryo Kawabata1,3, Hohei Koga3, Keisuke Yoshikawa2, Ikuko Yao1 (1. Kwansei Gakuin Univ., 2. Saitama Medical Univ., 3. Hyogo Medical Univ.)
[3P-721(3PS-14-05)]Sustaining microglial reparative function enhances stroke recovery
○Jun Tsuyama Tsuyama1, Ayaka Nakamura1,2, Takashi Shichita1 (1. Tokyo Medical and Dental University, 2. Keio University)
[3P-722]TSLP-mediated regulation of T cells contributes to neuroinflammation in neuropathic pain
○Atsushi Sakai1, Yuka Ino1,2, Motoyo Maruyama1,3, Masashi Ishikawa2, Ryosuke Arakawa1, Hidenori Suzuki1 (1. Dept. Pharmadol., Nippon Med. Sch., 2. Dept. Anesthesiol., Nippon Med. Sch., 3. Div. Lab. Anim. Sci., Nippon Med. Sch.)
[3P-723]Pathological effects of TARDBP mutation knockout in iPSC derived from ALS patients
○Sotaro Mizuno1, Tohru Sugawara2 (1. Yokohama City University, 2. Graduate School of Medical science, Yokohama City University)
[3P-724]Alteration of glucose tolerance and insulin secretion exhibited by a GLUT1DS model mouse
○Tamio Furuse1, Akiko Shinogi1, Mao Ozaki1, Ryoko Yanagisawa1, Tomoko Kushida1, Masaru Tamura1 (1. RIKEN BioResource Research Center)
[3P-725]The maintenance of unmyelinated small diameter axons by the expression and function of monocarboxylate transporters.
○Mio Fujisato1, Hinako Saito1, Riko Takahashi1, Reina Ono1, Ryunosuke Ohkawa1, Nobuharu Suzuki1 (1. Tokyo Medical and Dental University)
[3P-726]Suppression of neuroinflammation through brain-gut interaction by Monostroma nitidum ingestion in Cuprizone short-term treated mice
○Kentaro Nakashima1,3,4, Kyoka Tsukuda1,2,4, Ayaka Onishi3, Aoi Chiba4, Taku Nagamatsu4, Takashi Kubota4,5, Yasushi Kishimoto4,6 (1. Inst. Neurosci., Tokushima Bunri Univ., 2. Grad. Sch. Pharm. Sci., Tokushima Bunri Univ., 3. Kagawa Sch. Pharm. Sci., Tokushima Bunri Univ., 4. Lab. Biophysics, Kagawa Sch. Pharm. Sci., Tokushima Bunri Univ., 5. Dep. Pharm. Sci., Fac. Pharm. Sci., Teikyo Heisei Univ., 6. Lab. of Phys. Chem., Fac. Pharm. Sci., Teikyo Univ.)
[3P-727]Effects of disease-derived variants and of the interaction with Chromogranin B on the cell adhesion activity of Teneurin-4
○Reina Ono1, Mizuki Fukuhara1, Yuki Munakata1, Nanako Yamada1, Momona Yamada1, Nobuharu Suzuki1 (1. Tokyo Medical and Dental University)
[3P-728]Role of cohesin loader in gene expression and chromatin regulation of the inhibitory neuron during experience-dependent brain development
○Akiko Sakai1,2, Ryuichiro Nakato3, Gina Miku Oba3, Mai Saeki4, Eiko Saijo3, Yusuke Kishi3, Heiko Peters5, Katsuhiko Shirahige3, Sayaka Sugiyama2 (1. Brain Res. Inst., Niigata Univ, 2. Grad. Sch. Med. Dent. Sci., Niigata Univ., 3. Inst. Quant Biosci., Univ. of Tokyo, 4. Aquaever Co.,Ltd, 5. Newcastle Univ., UK)
[3P-729]Regulation of B cell responses by SLAM-family member 5 expressed on follicular dendritic cell
○Masaki Magari1, Kaho Takahashi1, Miku Nishioka1, Satomi Ohtsuka1, Hiroshi Tokumitsu1 (1. Grad. Sch. Interdiscip. Sci. and Eng. in Health Syst. Okayama Univ.)
[3P-730]BAFF is involved in the differentiation of monocytic cells with B cell-activating ability.
○Norika Mori1, Risa Nakatsuka2, Satomi Ohtsuka1, Hiroshi Tokumitsu1, Masaki Magari1 (1. Grad. Sch. Interdiscip. Sci. and Eng. in Health Syst. Okayama Univ., 2. Fac. Eng., Okayama Univ.)
[3P-731]BCR Signaling Pathways Modulating Gene Expression in Response to Varying Antigen Stimulation Intensities
○Wakana Ono1, Nozomi Yasufuku, Yuta Ito, Ryoya Yamanishi1, Naoki Kanayama1 (1. Molecular Cell Eng., Grad, Sch. Interdiscipl. Sci. Eng. Health Sys., Okayama Univ.)
[3P-732]Regulation of Immunoglobulin Somatic Hypermutation by Src Family Kinase Inhibitor-Responsive Factors
○Shiryu Michihiro1, Haruto Omori1, Misaki Akiyama1, Saki Obata2, Kazuyasu Chihara3, Kiyonao Sada3, Naoki Kanayama1 (1. Molecular Cell Eng., Grad, Sch. Interdiscipl. Sci. Eng. Health Sys., Okayama Univ., 2. Fac. Eng., Okayama Univ., 3. Genome Sci., Sch. Med. Sci., Fukui Univ.)
[3P-733]Functions of the RS Domain of SRSF1 in Somatic Hypermutation of Immunoglobulin Genes
○Chisa Ichikawa1, Ikuya Zaima1, Tomoyuki Ishibashi1, Naoki Kanayama1 (1. Molecular Cell Eng., Grad, Sch. Interdiscipl. Sci. Eng. Health Sys., Okayama Univ.)
[3P-734]Discovery of Therapeutic Target Molecules for Thrombotic Microangiopathy
○Satofumi Takaoka1, Ken Matsuoka1,2, Takatsugu Segawa1,3, Seiji Takashima1,2 (1. Department of Medical Biochemistry, Graduate School of Frontier Biosciences Osaka University, 2. Department of Medical Biochemistry, Osaka University Graduate School of Medicine, 3. Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine)
[3P-735(3AS-07-05)]TNF family cytokine RANKL and CD40L signaling maintain medullary thymic epithelial cells in the adult thymus
○Mio Hayama1,2, Taishin Akiyama1,2 (1. RIKEN Center for Integrative Medical Sciences, 2. Graduate School of Medical Life Science, Yokohama City University)
[3P-736]Mast cell-neutrophil interaction and neutrophil-expressed Ly6G modulates allergic responses
○Ami Igarashi1, Yuka Nagata1, Atsushi Furukawa1, Ryo Suzuki1 (1. Fac. Pharm. Sci., Kanazawa Univ.)
[3P-737]Cold response of bone-marrow-derived macrophages in mice
○Hiroki Sugimoto1, Takayuki Isagawa3,1, Takahiro Kuchimaru1, Kotaro Kiga4,2, Kazuhiko Miyanaga2, Longzhu Cui2, Norihiko Takeda5,1 (1. DCM, Jichi Med. Univ., 2. Bacteriol. Jichi Med. Univ., 3. Data Science, Jichi Med. Univ., 4. NIID, 5. DCM, The Univ. of Tokyo)
[3P-738]Harnessing an integrated glyco-nanovaccine technology for enhanced cancer immunotherapy
○Mayumi Niimura1, Yasuhisa Sakamoto1, Mayuko Shimoda1, Narumi Harada1, Ayato Maeda1, Shiho Wada3, Koki Murata3, Saisai Liu1, Haruka Ohara3, Yohei Kanamori1, Akihiro Nita1, Masahiro Wakao3, Hiroyuki Shinchi3, Toshiro Moroishi1,2 (1. Faculty of Life Sciences, Kumamoto University, 2. Center for Metabolic Regulation of Healthy Aging, Kumamoto University, 3. Graduate School of Science and Engineering, Kagoshima University)
[3P-739]Effects of antibiotics and lactoferrin in GFAP-Cre calcineurin Bαfl/fl mice in which small intestine inflammation is induced
Shimpei Goto1, Yuri Tanahashi1, Naohide Hirashima1, ○Masahiko Tanaka1 (1. Dept. of Cell. Biophys., Grad. Sch. of Pharmaceut. Sci., Nagoya City Univ.)
[3P-740]Pathophysiological role of chemokine CCL20 in inflammatory bowel disease.
○Nozomi Sachi1, Supanuch Ekronarongchai1, Yomei Kagoshima1, Yasuhiro Soga1, Misako Ueno1, Eiko Nakano1, Sotaro Ozaka1, Naganori Kamiyama1, Takashi Kobayashi1 (1. Department of Infectious Disease Control, Faculty of Medicine, Oita University)
[3P-741]Analysis of the chicken innate immune system's response to viral infections
○SHIHYUAN CHENG1, Satoko Kobayashi1, Kennosuke Ichikawa2, Tenkai Watanabe1,3, Takumi Terada1, Ryo Ezaki1, Mei Matsuzaki1, Yuko Uchida4, Hiroyuki Horiuchi1,3 (1. Graduate School of Integrated Sciences for Life, Hiroshima University, 2. The Roslin Institute, University of Edinburgh, 3. Hiroshima University Genome Editing Innovation Center, 4. National Institute of Animal Health, NARO)
[3P-742]Mechanisms of antigen presentation by mRNA-LNP
○Takeshi Nitta1,2, Suqi Wang2, Ryunosuke Muro1,2, Hiroshi Takayanagi2 (1. Tokyo Univ. Science, 2. Univ. Tokyo)
[3P-743]Deletion of the Ragulator complex in myeloid cells induces autoimmune disorder phenotypes in mice
○Yutaka Muto1, Kohei Tsujimoto1, Atsushi Kumanogoh1 (1. Osaka University)
[3P-744]HDAC3 Inhibition Enhances IL-37-dependent Anti-Inflammatory Pathway via SIGIRR/IL-18Rα Up-regulation
○Keiko Ueno-Shuto1, Ayami Fukuyama2, Megumi Hayashi2, Mary Ann Suico2, Hirofumi Kai2, Naofumi Tokutomi1, Tsuyoshi Shuto2 (1. Sojo Univ., 2. Kumamoto Univ.)
[3P-745]Micro-scale imaging of local immune response by inter-ray zymosan injection in Japanese Medaka (Oryzias latipes)
○Tsukasa Ryu1, Mizuki Yoshino2, William Ka Fai Tse2, Satoshi Ansai3, Taisen Iguchi 4, Anu Kumar5, Miki Nakao1, Yukiko Ogino2 (1. Biochemistry, Faculty of Agriculture, Kyushu Univ., 2. Bioresource Sci, Faculty of Agriculture, cPIER, Kyushu Univ. , 3. UMI, Okayama Univ., 4. Grad Sch of Nanobioscience, YCU, 5. CSIRO Environment, Australia)
[3P-746]Integrated single-cell transcriptomic analysis reveals the phenotypic and functional diversity of human natural killer cells during viral infections
○Lin Zhang1, Hafumi Nishi1,2, Kengo Kinoshita1 (1. Tohoku Univ., 2. Ochanomizu Univ.)
[3P-747]CANE accelerates activation of the NLRP3 inflammasome
○Naoe Kaneko1, Mie Kurata1,2, Toshihiro Yamamoto1, Akimasa Sakamoto3, Yasutsugu Takada3, Hidetaka Kosako4, Hiroyuki Takeda2, Tatsuya Sawasaki2, Junya Masumoto1,2 (1. Department of Analytical Pathology, Graduate School of Medicine, Ehime Univ. , 2. Proteo-Science Center, Ehime Univ., 3. Department of Hepatobiliary Pancreatic and Transplantation Surgery, Ehime Univ., 4. Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima Univ.)
[3P-748]Development of an in vitro skin sensitization test method considering metabolic activation by drug-metabolizing enzymes
○Yutaro OISHI1, Peiqi ZHAI1, Hiroki KOYAMA1, Kouichi KUROSE1 (1. Food Sci.and Tech.,TUMSAT)
[3P-749]Myd88/Trif signaling is essential for neurological recovery post-stroke
○Ryuki Koyama1, Takashi Shichita1, Jun Tsuyama1 (1. Tokyo Medical and Dental University Medical Research Institute department of Neuroinflammation and Repair)
[3P-750]Sublingual immune cell clusters and dendritic cell distribution in the oral cavity
○MICHIO TOMURA1, YUTAKA KUSUMOTO1, MAYUKO HASHIMOTO1, Tetsushi Hoshida2, Tsuneyasu Kaisho3 (1. LaboratoOsaka Ohtani University, 2. Laboratory for Cell Function Dynamics, RIKEN Center for Brain Science, 3. Department of Immunology, Institute of Advanced Medicine, Wakayama Medical University)
[3P-751]Disruption of lipid uptake and metabolism in human M2 macrophages by hydrophobic polybrominated flame retardants
Leila Khani1,3, Maciej Studzian1,2, Leonardo Martin1,4, ○Lukasz Pulaski1,2 (1. Laboratory of Trancriptional Regulation, Institute of Medical Biology PAS, Lodz, Poland, 2. Department of Oncobiology and Epigenetics, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland, 3. BioMedChem Doctoral School of the University of Lodz and Lodz Institutes of the Polish Academy of Sciences, Lodz, Poland, 4. Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium)
[3P-752]Effect of compounds from actinomycetes on cytokine gene expression in mouse keratinocyte
○Tomoyasu Ogura1, Atsushi Fukumoto2, Yohei Iizaka2, Yojiro Anzai2, Naoko Watanabe1, Masashi Ohtani1 (1. Lab. of Mol. Immunol., Dep. of Biomol. Sci., Fac. of Sci., Toho Univ., 2. Dept. of Microbiol., Fac. of Pharm. Sci., Toho Univ.)
[3P-753]Baicalein attenuates hepatic ischemia-reperfusion injury and partial hepatectomy in rats
○Tetsuya Okuyama1, Richi Nakatake1,2, Kentoro Ito3, Morihiko Ishizaki2, Hidesuke Yanagida1, Hiroaki Kitade1,2, Katsuhiko Yoshizawa4, Yoshinobu Ikeya5,6, Mikio Nishizawa3, Sohei Satoi1 (1. Department of Pancreatobiliary Surgery, Kansai Medical University, 2. Departments of Hepato-Biliary-Pancreatic Surgery, Kansai Medical University Medical Center, 3. Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, 4. Department of Innovative Food Sciences, School of Food Sciences and Nutrition, Mukogawa Women’s University, 5. Faculty of Pharmacy, Daiichi University of Pharmacy, 6. Research Organization of Science and Technology, Ritsumeikan University)
[3P-754]The synergistic anticancer effects of STAT3 siRNA-encapsulated PLGA nanoparticles targeting to transferrin receptor in cancer cells
○Chan mi Lee1, Jang Kyoung-Jin1 (1. sejong university)
[3P-755]Proteomic Analysis of Host Target Factors of Ivermectin in SARS-CoV-2 Infection
○Anna Kitajima1, Takayuki Uematsu1, Akari Ikeda2, Keisuke Nishida3, Nobuyoshi Baba3, Tomoyasu Hirose2, Hideaki Hanaki4, Toshiaki Sunazuka2 (1. Div. of Biomed. Res., Kitasato Univ. Med. Center, 2. Lab. of Bioorganic Chem., Ōmura Satoshi Mem. Inst., Kitasato Univ., 3. R&D Div., Meiji Seika Pharma Co., Ltd., 4. Infection Cont. Res. Center, Ōmura Satoshi Mem. Inst., Kitasato Univ.)
[3P-756]Analysis of Pharmacological Effects of Cepharanthine on SARS-CoV-2–Induced Disease in a Syrian Hamster Model
○Takayuki Uematsu1, Reiko Todaka2, Kei Haga2, Hideyuki Kobayashi3, Makiko Imajima3, Noritada Kobayashi1, Kazuhiko Katayama2, Hideaki Hanaki4 (1. Div. of Biomed. Res., Kitasato Univ. Med. Center, 2. Lab. of Virus Infection, Ōmura Satoshi Mem. Inst., Kitasato Univ., 3. Tokyo New Drag Discov. Res. Lab., Kowa Co., Ltd., 4. Infection Cont. Res. Center, Ōmura Satoshi Mem. Inst., Kitasato Univ.)
[3P-757]Evaluation of anti-SARS-CoV-2 activity of Prunus mume extract and analysis of its mechanism of action
○Kanako Hirata1, Mizuki Tokusanai1, Koichiro Tateishi1, Chikara Kato1, Ryohei Kono2, Sorama Natsumi3, Susumu Takekoshi1, Yoshiharu Okuno3, Hirotoshi Utsunomiya 2, Norio Yamamoto1 (1. Department of Microbiology, Tokai University School of Medicine, 2. Osaka Kawasaki Rehabilitation University, 3. National Institute of Technology, Wakayama College)
[3P-758]Evaluation of antiviral activity of Prunus mume extracts against influenza viruses and elucidation of its molecular mechanisms.
○Mizuki Tokusanai1, Kanako Hirata1, Koichiro Tateishi1, Chikara Kato1, Ryohei Kono2, Sorama Natsumi3, Susumu Takekoshi1, Yoshiharu Okuno3, Hirotoshi Utsunomiya2, Norio Yamamoto1 (1. Affiliation: Department of Microbiology, Tokai University School of Medicine, 2. Osaka Kawasaki Rehabilitation University, 3. National Institute of Technology, Wakayama College)
[3P-759(3MS-01-02)]Arf6 is required for cytokine storm through the prion-like transmission of ASC specks upon influenza A virus infection
○Rois Muqsith Fatawy1,2, SangJoon Lee1, Honami Takahashi1, Yuji Funakoshi1, Atsushi Kawaguchi1 (1. Department of Infection Biology, Institute of Medicine, University of Tsukuba, 2. PhD Program in Human Biology, Graduate School of Comprehensive Human Science, University of Tsukuba)
[3P-760]Modeling Urinary Tract Infection (UTI) using hiPSCs-derived bladder organoids
○Mizuki Fukuda1,2, Kazuhiro Ofuji1, Minoru Takasato1,2 (1. RIKEN BDR, 2. Kyoto University・Biostudies)
[3P-761]The neutralizing activity against SARS-CoV-2 is enhanced by mixing VHH antibodies that recognize different epitopes.
○Reiko Todaka1, Kei Haga1, Hidekazu Masaki2, Masayuki Tsuchiya2, Naoto Nemoto2, Yuta Matsumura3, Hiroki Nishiguchi3, Takuto Thojo3, Akihito Kawahara3, Hibiki Kawano3, Takuya Morimoto3, Kazuhiko Katayama1 (1. Kitasato University, Ōmura Satoshi Memorial Institute, 2. Epsilon Molecular Engineering Inc., 3. Kao Corporation)
[3P-762]Characterization of SARS-CoV-2 with mutations in viral nsp5 gene
○Michihito Sasaki1,2, Yukari Itakura2, Koshiro Tabata2, Shinji Kusakabe1,3, Kei Konishi1,3, Tatsuki Sugi1, Jyunya Yamagishi1,4, Nijiho Kawaguchi1, Eri Fuji1, Akihiko Sato1,2,3, Hirofumi Sawa1,2,4, Yasuko Orba1,2,4 (1. Hokkaido Univ. IIZC., 2. Hokkaido Univ. IVReD., 3. Shionogi & Co., Ltd., 4. Hokkaido Univ. OHRC.)
[3P-763]A new mouse model mimics pneumonia caused by RSV infection
○Tatsuki Takahashi1, Sodbayasgalan Amarbayasgalan1, Yoshiro Sugiura1, Shiori Ueno2,1, Dorjsuren Enkhjin1, Kenta Shimizu1, Wataru Kamitani1 (1. Gunma Univ., 2. NIID)
[3P-764]Optimizing Optically Controllable Measles Virus Vectors for Oncolytic Virotherapy
○Yuying Wang1, Maino Tahara2, Takashi Okura2, Hideko Watabe1, Yukiko Akahori1, Hiroshi Katoh1, Takaaki Tsunematsu3, Naozumi Ishimaru4, Shohei Miyamoto5, Masayuki Tsukasaki6, Kenzaburo Tani7, Moritoshi Sato8, Makoto Takeda1 (1. Department of Microbiology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, 2. Department of Virology 3, National Institute of Infectious Diseases, 3. Department of Oral Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences, 4. Department of Oral Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 5. Division of Oncology, Research Center for Medical Sciences, The Jikei University School of Medicine, 6. Department of Osteoimmunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, 7. The Institute of Medical Science of Tokyo, The University of Tokyo, 8. Graduate School of Arts and Sciences, The University of Tokyo)
[3P-765]β-d-N4-hydroxycytidine, a metabolite of molnupiravir, exhibits in vitro antiviral activity against rabies virus
○Kei Konishi1,2, Shinji Kusakabe1,2, Nijiho Kawaguchi1, Takao Shishido2, Naoto Ito3, Yasuko Orba1,4,5, Hirofumi Sawa1,4,5, Michihito Sasaki1,4, Akihiko Sato1,2,4 (1. International Institute for Zoonosis Control, Hokkaido University, 2. Laboratory for Drug Discovery & Disease Research, Shionogi & Co., Ltd, 3. Faculty of Applied Biological Sciences, Gifu University, 4. Institute for Vaccine Research and Development, Hokkaido University, 5. One Health Research Center, Hokkaido University)
[3P-766]Structural basis for Ebola virus nucleocapsid assembly and function regulated by VP24
○Yoko Fujita-Fujiharu1,2,3, Shangfan Hu2,3,4, Ai Hirabayashi2,3, Yuki Takamatsu4, Yen Ni Ng2,3, Kazuya Houri2,3, Yukiko Muramoto2,3, Masahiro Nakano2,3, Yukihiko Sugita2,3,5, Takeshi Noda2,3 (1. Max Planck Institute of Biochemistry, 2. Lab. of Ultrastructural Virology, LiME, Kyoto Univ., 3. Lab. of Ultrastructural Virology, GSB, Kyoto Univ., 4. Dept. of Virology, NEKKEN, Nagasaki Univ., 5. Hakubi Center, Kyoto Univ.)
[3P-767]Inhibition of Tick-borne encephalitis virus propagation by Locked Nucleic Acid gapmers targeting stem-loop structures in vitro.
○Shunsuke Okamoto1, Mizuki Fukuta1, Yuji Fujii1, Minato Hirano1, Yusuke Echigoya2, Kentaro Yoshii1 (1. Department of Viral Ecology, National Research Center for the Control and Prevention of Infectious Diseases (CCPID), Nagasaki University, 2. Laboratory of Biomedical Science, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University)
[3P-768]Generation and characterization of monoclonal antibodies against Cutibacterium acnes
○Rio Iwasaki1, Yuka Ogura2, Chikako Yokoyama1, Taro Tachibana1 (1. Osaka Metro. Univ., 2. Osaka City Univ.)
[3P-769]Sequence analysis of the long RNA genome SARS-CoV-2 by full-length reverse transcription and amplification
○Hiroko Matsunaga1,2, Lin Chia-Ling3, Chika So3, Koki Numakura3,4, Tadaki Suzuki4, Haruko Takeyama1,2,3,5 (1. Res. Org. Nano Life Innov., Waseda Univ., 2. CBBD-OIL, AIST-Waseda Univ., 3. Grad. Sch. Adv. Sci. Eng., Waseda Univ, 4. Dept. Pathol., NIID, 5. Inst. Adv. Res. Biosyst. Dynam., Waseda Res. Inst. Sci. Eng., Waseda Univ)
[3P-770]The establishment and analysis of the 3 nt-deletion CHIKV genome library
○Rie Doi1,2, Shimon Goto2, Fumiyo Ogawa1,2, Hirotaka Ebina1,2 (1. BIKEN Innovative Vaccine Research Alliance Laboratories, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, 2. The Research Foundation for Microbial Diseases of Osaka University)
[3P-771]SARS-CoV-2 papain-like protease inhibitory activity of natural derived components focusing on the steroid skeleton.
○Yuka Kiba1, Takashi Tanikawa1, Masashi Kitamura1 (1. Josai Univ.)
[3P-772]Cryo-EM analysis of the nucleosomes containing Plasmodium falciparum histones
○Shoko Sato1, Mariko Dacher1, Yoshimasa Takizawa1, Kankichi Murayama1,2, Mitsuo Ogasawara1, Yutaro Fukushima1,2, Indu Patwal3, Andrew Flaus3, Hitoshi Kurumizaka1,2 (1. IQB, Univ. of Tokyo, 2. Dep. of Biol. Sci., Univ. of Tokyo, 3. Sch. of Nat. Sci., NUI Galway)
[3P-773]Involvement of Ribosomal Protein L17 and Y-Box Binding Protein 1 in Assembly of Hepatitis C Virus Potentially via Their Interaction with the 3’ Untranslated Region of the Viral Genome
○Masahiko Ito1, Liu Jie1, Tetsuro Suzuki1 (1. Hamamatsu University School of Medicine)
[3P-774]Mechanism of antibacterial action of AMP against Cryptococcus neoformans
○Koki Watanabe1, Michiyo Honda1 (1. Graduate School of Science and Technology, Meiji university)
[3P-775]Establishment of the high-avidity or low-avidity cells for hemagglutinin of Influenza A virus
○Akihiro Maekawa1, Takahiro Hiono2, Yoshihiro Sakoda3, Hiroshi Kida4, Akira Togayachi1,5, Shoko Nishihara1,5, Sayaka Takase-Yoden1,5 (1. Department of Biosciences, Graduate School of Science and Engineering, Soka University, 2. One Health Research Center, Hokkaido University, 3. Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, 4. Hokkaido University International Institute for Zoonosis Control, 5. Glycan and Life Systems Integration Center (GaLSIC), Soka University)
[3P-776]Identification of host factors involved in RNA virus replication
○Makoto Shimooka1, Tokiko Watanabe1,2,3 (1. Research Institute for Microbial Diseases, Osaka University, 2. Center for Infectious Disease Education and Research (CiDER), Osaka University, 3. Center for Advanced Modalities and DDS (CAMaD), Osaka University)
[3P-777]AS03-like adjuvant effects in West Nile virus subunit vaccines
○Atsuko Inoue1,2, Yukari Itakura1, Shinji Saito1, Katsumi Maenaka1,2,3,4,5, Hirofumi Sawa1,3,6, Yasuko Orba1,3, Koshiro Tabata1 (1. Institute for Vaccine Research and Development, Hokkaido University, Japan, 2. Faculty of Pharmaceutical Science, Graduate School of Life Science, Hokkaido University, Japan, 3. International Institute for Zoonosis Control, Hokkaido University, Japan, 4. Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Japan, 5. Global Station for Biosurfaces and Drug Discovery, Hokkaido University, Japan, 6. One Health Research Center, Hokkaido University, Japan)
[3P-778]Discovery of diverse RNA viruses from various environments using NeoRdRp
○So Nakagawa1, Shoichi Sakaguchi2 (1. Tokai Univ., 2. Osaka Med. Pharm. Univ.)
[3P-779]Isolation of male-specific bacteriophages and killing of drug-resistant Inc plasmid-carrying bacteria
○Mitsuoki Kawano1, Kotaro Oda1, Fuka Nakamura1, Riko Nakanishi1 (1. Nakamura Gakuen University)
[3P-780]The structural insight into receptor binding domain mobility of SARS-CoV-2 BA.2.86 S protein.
○Hisano Yajima1, Yuki Anraku2, Yoshiko Nakura1, Kanako Terakado Kimura1, Shunsuke Kita2, Arnon Plianchaisuk3, Kaho Okumura3, Yusuke Atarashi1,4, Takuya Hemmi1, Daisuke Kuroda4, Yoshimasa Takahashi, Shunsuke Kita2, Jiei Sasaki1, Hiromi Sumita5, Jumpei Ito, Katsumi Maenaka2, Kei Sato3, Takao Hashiguchi1 (1. Laboratory of Medical Virology, LiMe., Kyoto Univ. , 2. Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences,Hokkaido Univ., 3. Division of Systems Virology, Department of Microbiology and Immunology,The Univ. of Tokyo, 4. Research Center for Drug and Vaccine Development,NIID., 5. Research Administration Office, LiMe., Kyoto Univ.)
[3P-781(3MS-07-02)]A gut ceramidase activity determines the species- and strain-specific aging speed
○Ayami Takaochi1, Kota Abe1, Tohru Ishitani1 (1. Osaka university, RIMD)
[3P-782]xrcc5 knockout zebrafish exhibits aging-like phenotype prematurely
○Kota Ujibe1, Yasuko Honjo2, Makoto Kashima3, Seiji Wada1, Hiromi Hirata1 (1. Aoyama Gakuin University, 2. Research Institute for Radiation Biology and Medicine, Hiroshima University, 3. Toho University)
[3P-783]The role of senescent cells in chronic pulmonary disease: implications for lung repair
○Mikako Hirose1, Hiromichi Tsushima1, Masataka Sugimoto1,2 (1. Tokyo Metropolitan Institute for Geriatrics and Gerontology, 2. National Center for Geriatrics and Gerontology)
[3P-784]Lysine-specific demethylase 1 (LSD1) suppresses cellular senescence by riboflavin uptake-dependent demethylation activity.
○Taiichi Osumi1, Taiki Nagano2, Tetsushi Iwasaki1,2, Jotaro Nakanishi3, Kazuyuki Miyazawa3, Shinji Kamada1,2 (1. Department of Biology, Graduate School of Science, Kobe University, 2. Biosignal Research Center, Kobe University, 3. MIRAI Technology Institute, Business Core Technology Center, Shiseido Co., LTD)
[3P-785]Spontaneous p53 activation in middle-aged C57BL/6 mice mitigates the lifespan-extending adaptive response induced by low-dose ionizing radiation.
○Masaoki Kohzaki1, Keiji Suzuki2, Akira Ootsuyama1, Ryuji Okazaki1 (1. University of Occupational and Environmental Health, Japan, 2. Nagasaki University)
[3P-786]Natural killer cells eliminate senescent dermal fibroblasts
○Ayami Iijima1, Tatsuya Hasegawa1 (1. MIRAI Technology Institute, Shiseido Co., Ltd., Yokohama, Japan)
[3P-787]Novel glucocorticoid secretory pathways and mechanisms of adrenal aging
○Noriyuki Okudaira1, Misato Terahara1, Takao Susa1, Miho Akimoto1, Harumi Hisaki1, Masayoshi Iizuka1,2, Noboru Ogiso3, Mimi Tamamori-Adachi1 (1. Teikyo Univ. Dept Biochem., 2. Teikyo Univ. Med Edu Ctr., 3. NCGG. Dept Lab Exp Ani.)
[3P-788]Diversity of Cellular Senescence and Its Regulation, Linkage with Individual Aging
○Yoichiro Kawabe1, Yuma Sugiyama1, Tanenobu Harada1, Mitsuo Maruyama1,2 (1. National Center for Geriatrics and Gerontology, 2. Nagoya University Graduate School of Medicine)
[3P-789]Evaluation of the Effects of αG-Rutin on the Inhibition of Telomere Shortening
○Takumi Terada1, Vinodh J Sahayasheela1, Ryohei Noizumi1, Akihito Nakanishi2, Tandia Mahamadou2, Hiroshi Sugiyama3 (1. Kyoto Univ., 2. Toyo Sugar Refining Co., Ltd., 3. Kyoto Univ. iCeMS)
[3P-790]Development of an adenosine phosphate prodrug regulating energy metabolism and aging
○Takahisa Anada1, Michiharu Kawahara1, Taisei Shimada1, Ryotaro Kuroda1, Haruto Maeda1, Eriko Nakadai2, Masaru Tanaka1 (1. Kyushu University, 2. Kyoto University)
[3P-791]Decreased intracellular NAD+ in human umbilical vein endothelial cells promotes COX2-induced prostanoid production
○Natsuko Kitajima1, Takahisa Nakajo1, Takeshi Katayoshi1, Kentaro Tsuji1 (1. DHC corporation)
[3P-792(3PS-14-02)]Understanding skeletal muscle aging mechanisms through changes of dorsoventral patterns with aging
○Hikaru Ino1, Kota Abe1, Tohru Ishitani1 (1. Department of Homeostatic Regulation, Division of Cellular and Molecular Biology. Research Institute for Microbial Diseases, Osaka University)
[3P-793]Skin improvement effects of elastin-derived peptides
○Taiki TSUBAKI1 (1. Kyushu Univ. Graduate School of Systems Life Sciences)
[3P-794]Effects of resveratrol, an activator of SIRT1, on aging-related skin thinning in mice.
○Fuka Tamura1, Ryusuke Hosoda1, Iyori Nojima1, Atsushi Kuno1 (1. Sapporo Medical Univ.)
[3P-795]The signaling network governing intestinal stem cell homeostasis during aging
○May Nakajima-Koyama1, Eisuke Nishida2, Takuya Yamamoto1,3,4 (1. CiRA, Kyoto Univ., 2. RIKEN, BDR, 3. ASHBi, Kyoto Univ., 4. RIKEN, AIP)
[3P-796]Novel molecular mechanisms in the regulation of chronic inflammation during aging
○Mami Yamada1, Eiji Warabi2, Hisashi Oishi3, Mitsuharu Okutsu1 (1. Nagoya City Univ. Grad. Sch. of Sci., 2. Tsukuba Univ. , 3. Nagoya City Univ. Grad. Sch. of Med. Sci.)
[3P-797]Behavioral analysis of age-related changes in coordinated motor learning ability in mice using spontaneous running wheel test
○Takuro Honzawa1, Etsumi Oike1, Shunya Hanzawa1, Yuka Moriya1, Eiko Matsumoto1, Eriko Urano1, Yuriko Hayashi2, Hiroshi Ohnishi1 (1. Dept･Lab･Sci,･Gunma･Univ･Grad･Sch･Health･Sci,･Gunma,･Japan, 2. Dept･Health･Sci,･Gunma･PAZ･Univ･Grad･Sch･Health･Sci,･Gunma,･Japan)
[3P-798]Involvement of HP1 in functional expression of BAF
○Yuga Mori1, Ayumi Takemura1, Yurika Kinoshita1, Shoichi Tsujikawa1, Taro Mannen1, Toshiya Hayano1 (1. Ritsumeikan Univ. Col.of Life Sci.)
[3P-799]Analysis of the Effects of Hepatic Wdr6 siRNA Introduction on Disease Progression in a Non-Alcoholic Steatohepatitis (NASH/MASH) Mouse Model
○Tatsunobu Nakagawa1, Yuki Yoshii1, Jinyun Wang1, Issa Furihata1, Toshimitsu Komatsu2, Isao Shimokawa2, Akihito Ishigami3, Yoshitaka Kondo3, Takuya Chiba1 (1. Biomed. Gerontol. Lab., Faculty of Human Sci., Waseda Univ., 2. Grad. Sch. Biomed. Sci., Nagasaki Univ., 3. Mol. Reg. of Aging, TMIG)
[3P-800]Enhancement of physical performance by Ninjin'yoeito
○Kaita Hirano1, Jihwan Eum1, Yuko Futagami1, Ryuji Takahashi2, Akio Inui3, Kazuhiro Shiozaki1 (1. Div. Food Life Sci., Fac. Fish., Kagoshima Univ., 2. Kampo Res. Lab., Kracie Ltd., 3. Pharm. Dep. Herb. Med., Grad. Sch. Med. Dent. Sci., Kagoshima Univ.)
[3P-801]Molecular basis for activation of gut-brain correlation by Urolithin A
○Yuki Kiyomizu1, Daiki Kubota2, Akiko Kohara3, Masahiro Kudo3, Yuichi Ukawa3, Kiichiro Teruya4, Yoshinori Katakura4 (1. Graduate School of Systems Life Sciences Kyushu University, 2. Graduate School of Bioresource and Bioenvironmental Sciences Kyushu University, 3. Daicel Corporation, 4. Faculty of Agriculture Kyushu University)
[3P-802]Elucidating the heterogenity of skeltal muscle stem cells with aging by using single-cell ATAC-seq analysis
○Yuki Goda1, Yusuke Ono1,2 (1. Tokyo Metropolitan Institute for Geriatrics and Gerontology, 2. Department of Muscle Development and Regeneration, Institute of Molecular Embryology and Genetics, Kumamoto Univ)
[3P-803]Identification of aging-related genes in brain vascular endothelial cells using public single-cell transcriptome databases
○Yuya Sato1, Kazuhiro Takara2,3, Wataru Onodera1, Hiroyasu Kidoya2, Toru Asahi1,4, Kosuke Kataoka4,5 (1. Dept. of Adv. Sci. Eng., Grad. Sch. of Adv. Sci. Eng., Waseda Univ., 2. Dept. of Integ. Vasc. Biol., Faculty of Med. Sci., Univ. of Fukui, 3. Tenure-Track Prog. for Innovative Res., Univ. of Fukui, 4. Dept. of Comp. Res. Org., Waseda Univ., 5. Grad. Sch. Eng., Tokyo Univ. of Agric. and Tech.)
[3P-805]Extracellular vesicles from bone marrow derived mesenchymal stem cell rescue retinal cells from oxidative stress and attenuate corneal neovascularization
○Hisaki Hayashi1 (1. Aichi Medical University)
[3P-806]Preliminary study on the balance of radiation-induced cell death pathways in p53-mutated human glioblastoma cells
○Juri Kidachi1, Hisashi Nakano2, Mitsuki Imazato1, Mizuki Kojima3, Kaori Tsutsumi3 (1. Hokkaido Univ., School of Medicine, 2. Niigata Univ. Hosp., Department of Radiation Oncology, 3. Hokkaido Univ., Faculty of Health Sciences)
[3P-807]Role of NRP-1 on the radio-sensitivity of human glioblastoma cell line T98G
○Mitsuki Imazato1, Hisashi Nakano2, Juri Kidachi1, Mizuki Kojima3, Kaori Tsutsumi3 (1. Hokkaido Univ., School of Medicine, 2. Niigata Univ. Hosp., Department of Radiation Oncology, 3. Hokkaido Univ., Faculty of Health Sciences)
[3P-808]Effects of FXR Agonist GW4064 on the Migration and Invasion in Human Glioblastoma Multiforme
○Ying Chen1, Yi-Hsuan Lin1, Tzu-Min Chen1 (1. National Defense Medical Center)
[3P-809]SBI-115 inhibits migration and invasion through cAMP/p-CREB downregulation in human bladder cancer
○Yi-Hsuan Lin1, Chien-Chang Kao2, Tzu-Min Chen1, Ying Chen1, Sheng-Tang Wu2,3 (1. National Defense Medical Center, 2. Tri-Service General Hospital, 3. Hualien Armed Forces General Hospital)
[3P-810]Farnesoid X receptor overexpression suppresses migration, invasion, and angiogenesis ability in human glioblastoma cells via JAK2/STAT5 cascade
○TZU MIN CHEN1, Ying Chen1 (1. National Defense Medical Center)
[3P-811]Investigation of the TGR5 Impact on Glioma Cell Viability and mobility
○NI WEI1, Ying Chen1 (1. National Defense Medical Center)
[3P-812]To investigate the effect of tumor-associated macrophages and microglia regulated by FXR
in glioma cells
○YaoSheng Wu1, Ying Chen1 (1. National Defense Medical Center)
[3P-813]Involvement of Eiger-JNK signaling and Upd3 in hemocyte-mediated tumor recognition and induction of the Tot proteins having anti-tumor effect in the fat body
○Juri Kinoshita1,2, Tadashi Nomura1,2, Yoshihiro H Inoue2 (1. Biomedical Res. Ctr., Kyoto Inst. Tech. , 2. Grad. Sch. of Sci. Tech., Kyoto Inst. Tech.)
[3P-814]Mechanism of how antimicrobial peptides, Drosocin and Cecropin A exhibit anti-tumor effects against tumors generated in hematopoietic tissues in Drosophila mxc mutant larvae
○Marina Hirata1,2, Tadashi Nomura1,2, Yoshihiro H. Inoue1 (1. Biomedical Res. Ctr., Kyoto Inst. Tech., 2. Grad. Sch. of Sci. Tech., Kyoto Inst. Tech.)
[3P-815]Regulatory mechanism of cell death induced by the transcription factor E2F1 independent of the tumor suppressor p53
○Rinka Nakajima1, Kiyoshi Ohtani1 (1. Kwansei Gakuin Univ.)
[3P-816]WDR1 forms feed forward loop in E2F1 mediated tumor suppressive mechanism
○Mashiro Shirasawa1, Kiyoshi Ohtani1 (1. Kwansei Gakuin University)
[3P-817]Distinct regulation of tumor suppressor genes by the transcription factor E2F in epithelial cells
○Yaxuan Zhou1 (1. Graduate School of Science and Technology, Kwansei Gakuin University)
[3P-819(3MS-14-06)]Identification of cell competition markers
○Eilma Akter1, Olivia Marchia Kusuma1, Takahiro Kuchimaru3, Shunsuke Kon2 (1. Tokyo Univ. of Sci., Grad. Sch. of Bio. Sci. , 2. Tokyo Univ. of Sci., Res. Inst. for Bio. Sci., 3. Jichi Med. Univ. Ctr. for Mol. Med.)
[3P-820]Analysis of epitranscriptomic regulation by RNA demethylase ALKBH3 in pancreatic cancer
○Manami Yamada1, Shuntaro Aoi2, Honoka Kitamura1, Kaori Kitae1, Hiroaki Hase1, Kentaro Jingushi1, Yuko Ueda1, Kazutake Tsujikawa1 (1. Lab. Mol. Cell. Physiol., Grad. Sch. Pharm. Sci., UOsaka., 2. Lab. Mol. Cell. Physiol., Sch. Pharm. Sci., UOsaka.)
[3P-821(3MS-14-07)]Quantitative live imaging of ERK MAPK and AMPK activity in patient-derived pancreatic cancer organoids
○Toru Hiratsuka1, Shoko Tsukamoto2, Houssam Alkoussa2, Akihito Machinaga3, Nobuyuki Kakiuchi4, Seishi Ogawa5,6,7, Hiroshi Seno4, Shigeki Higashiyama1, Michiyuki Matsuda2 (1. Osaka International Cancer Institute, 2. Lab. of Cell Cycle Regulation, Kyoto Univ., 3. Discovery, Med. Creation, OBG, Eisai Co., Ltd,, 4. Dept. of Gastroenterol and Hepatol., Kyoto Univ., 5. Dept. of Pathol. and Tumor Biol., Kyoto Univ., 6. WPI-ASHBi, Kyoto Univ., 7. Dept. Med., Karolinska Inst., Stockholm, Sweden)
[3P-822]LncRNA MANCR post-transcriptionally regulates CD44 expression in pancreatic cancer cells.
○Souichi Oe1, Teruhide Sato1, Mai Hidaka1, Shinich Hayashi1, Taro Koike1, Ryohei Seki1, Yousuke Nakano1, Yuki Sato1, Hikaru Iwashita1, Yukie Hirahara2, Masaaki Kitada1 (1. Dept. Anat. Kansai Med. Univ. , 2. Faculty of Nursing, Kansai Med. Univ)
[3P-823]Acquisition of malignant transformation via cancer cell fusion.
○Shuuji Mawaribuchi1, Yoshikazu Haramoto2, Maiko Iida1 (1. CMB, AIST, 2. Coll. of Agric., Tamagawa Univ.)
[3P-824]Exploring genes involved in anoikis resistance
in ovarian cancer using the CRISPR/Cas9 libraries
○Shiori Mori1, Vu Duc Anh1, Takeharu Sakamoto1 (1. Dept of Cancer bio, Kansai med Univ.)
[3P-825]EWSR1 suppresses promoter activity of E2F target tumor suppressor genes
○Yusei Kajikawa1, Kiyosi Otani1 (1. Kwansei Gakuin University)
[3P-826]Accumulation of hypoxia-inducible factors HIF-1/2α under hypoxic culture conditions does not upregulate an essential amino acid transporter LAT1 in colorectal cancer cells
○Ryuichi Ohgaki1,2, Yuma Hirase1, Minhui Xu1, Hiroki Okanishi1, Yoshikatu Kanai1,2,3 (1. Grad. Sch. Med., Osaka Univ., 2. iFremed, OTRI, Osaka Univ., 3. WPI-PRIMe, Osaka Univ.)
[3P-827]Transcriptomic and Epigenetic Characteristics of Drug-Tolerant Persisters in Pancreatic Cancer Cell Lines
○YUXIAO YANG1,2, Kenichi Miyata1,3, Chikako Shibata1, Takaaki Furukawa1, Reo Maruyama1,3 (1. Cancer Epigenomics, Cancer Inst., JFCR, 2. Grad. of Med&Dent., TMD Univ., 3. NEXT-Ganken Program, JFCR)
[3P-828]Regulation of proliferation and pluripotency by DPPA2, 4 in lung adenocarcinoma cell lines
○Yurika Takada1, Aya Shiba2, Tomoki Nakagawa3, Hazime Yasuda3, Daisuke Matsubara2 (1. University of Tsukuba, 2. University of Tsukuba, Institute of Medicine, 3. University of Tsukuba Hospital, Department of Diagnostic Pathology)
[3P-829]The mechanism of tumor suppression through METTL7, a novel nutrient senser
○Ayana Fuse1, Sumire Nakagawa1, Arisa Hoashi1, Mayu Asao2, Miyuki Nishida2, Maki Sugaya2, Sho Aki1,2, Tsuyoshi Osawa1,2 (1. Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, 2. Research Center for Advanced Science and Technology, The University of Tokyo)
[3P-830]Regulation of inflammatory cytokine expression via post-transcriptional regulation of mRNA by the Hippo pathway
○Haruna Tanaka1, Tomoki Chiba1, Uchida Yutaro1, Nao Watanabe1, Misao Takemoto1, Ryota Kurimoto1, Hiroshi Asahara1 (1. Institute of Science Tokyo)
[3P-831]Relationship between assumed Bone Microenvironment factors and Mesenchymal-Epithelial Transition using A549 lung cancer cell line.
○Hiroto Shimokawa1, Kazuki Okada2, Takara Shouji2, Takashi Narai3, Yuji Nakayama4, Toshihiko Kishimoto2, Kenji Kokura2 (1. Dept. of Biomol. Sci., Grad. Sch. of Sci., Toho Univ, 2. Dept. of Biomol. Sci., Fac. Sch. of Sci., Toho Univ. , 3. Div. Oral Maxillofacial Surgery, Fac. of Medicine, Tottori Univ., 4. Div. Radioisotope, Org. Res. Initiative Promotion, Tottori Univ.)
[3P-832]Vasorin/slit-like 2 induced by TGF-b signaling accelerates cellular migration in gastric cancer cells
○Yoko Yasuda1, Tomoaki Koga2, Yuki Tateishi1, Tomoko Kimura1, Shinichi Mizuno1, Mitsuyoshi Nakao2 (1. Kyushu Univ., 2. Kumamoto Univ.)
[3P-833]Analysis of physiological functions of fatty acid-binding proteins in breast cancer cells
○Honoka Watanabe1, Koichiro Kawaguchi1 (1. Kyoto Institute of Technology, Undergraduate Program of Applied Biology)
[3P-834]Studies on nuclear receptor FXR signal pathway in colorectal cancer cells
○Rin Shinozaki1, Koichiro Kawaguchi1 (1. Kyoto Institute of Technology・Master's Program of Applied Biology)
[3P-835]Effect of olfactory receptor OR7C1 on colorectal cancer stemness
○Kaoru Hashimoto1, Yoshihiko Hirohashi2, Toshihiko Torigoe2, Masafumi Yohda1, Yosuke Fukutani1 (1. Dept. of Biotechnol. Tokyo Univ. of Agric. and Technol., 2. Dept of Pathol. Sapporo Med. Univ.)
[3P-836]Pathophysiological functions of CRBN
○rika okumura1, yuki yamaguchi1 (1. Tokyo Institute of Technology)
[3P-837]Functional analysis of variant of uncertain significance mutation of FBXW7 in colorectal cancer.
○Sayoko Okamoto1, Rina Nishikawa1, Keiichi Hatakeyama2, Tsuyoshi Tanaka1, Tomoko Yoshino1 (1. Tokyo University of Agriculture and Technology, 2. Shizuoka Cancer Center Research Institute)
[3P-838(3MS-14-05)]Tumor heterogeneity of branched-chain amino acid and the activated metabolism regulates the aggressive nature in human triple-negative breast cancer
○Kenkyo Matsuura1, Itsuki Kuroda1,2, Ririko Shinonaga1,2, Mizuki Yamamoto3, Jun-ichiro Inoue3, Hiromi Imamura4, Ayuna Hattori1, Takahiro Ito1 (1. Inst. for Life and Med. Sci., Kyoto Univ., 2. Grad. Sch. of Pharm. Sci., Kyoto Univ., 3. Inst. for Med. Sci., Univ. of Tokyo, 4. Grad. Sch. of Biostudies, Kyoto Univ.)
[3P-839]Investigation of cells expressed somatic mutation in the mitochondrial respiratory chain complex gene detected in breast cancer
○Kenji Watanabe1, Shigeru Yamamoto2, Noriko Maeda2, Naruyo Nishimura1, Keishiro Isayama1, Mikako Yagi4, Dongchon Kang3, Masaaki Oka2, Hiroaki Nagano2, Yoichi Mizukami1 (1. Institute of Gene Research, Science Research Center, Univ. of Yamaguchi, 2. Dept. of Digestive Surgery and Surgical Oncology, Grad. Sch. of Med., Univ. of Yamaguchi, 3. Dept. of Clinical Chemistry and Laboratory Medicine, Grad. Sch. of Med. Sci., Univ. of Kyushu, 4. Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University)
[3P-840]Effects of cancer cell-derived migrasomes on angiogenesis
○Yuka Iwasaki1, Shogo Saito1, Mina Okochi1 (1. Institute of Science Tokyo)
[3P-841]Breakthrough the molecular mechanisms related to changes in HER2 expression using HER2-positive breast cancer cell lines
○Shota Katayama1, Jun Nakayama2, Kentaro Semba1,3 (1. Dept. of Life Sci. & Biomed. Sci., Grad. Sch. of Sci. & Eng., Waseda Univ., 2. Dept. of Oncogenesis Growth Regulation, Res Inst., Osaka Intl. Cancer Inst., 3. TR center, Univ. of Fukushima Med.)
[3P-842]Functions of Galanin in Invasion of Human Colorectal Cancer Cells
○Juri Tashima1, kazuki kajizuka1, Aika Okamoto1, Kosuke Tashiro1 (1. Kyushu Univ.)
[3P-843]p53 negatively regulates the expression of the nuclear export protein XPO1, establishing a positive feedback loop
○Yasushi Sasaki1, Asami Matsuda1, Masashi Idogawa2, Hiromu Suzuki3, Takashi Tokino2 (1. Sapporo Medical University, 2. Sapporo Medical University School of Medicine, Medical Genome Sciences, 3. Sapporo Medical University School of Medicine, Molecular Biology)
[3P-844]Understanding the mechanisms of cancer stem cell maintenance and differentiation using models to induce differentiation
○Shojiro Kitajima1, Yuki Nishida1, Nobuaki Kono1, Takeshi Masuda1, Tomoyoshi Soga1, Yasusei Kudo2 (1. Inst. for Adv. Biosci., Keio Univ., 2. Oral Biosci., Grad Sch. of Biomed. Sci., Tokushima Univ.)
[3P-845]Potential Enhancement of Therapeutic Efficacy of Silibinin Through Cytokine Expression in Ovarian Clear Cell Carcinoma Cell Lines
○Mariko Miyazawa1, Yoshie Kametani2, Takeshi Hirasawa1, Shino Oshima2, Masaki Miyazawa1, Masanori Yasuda3, Mikio Mikami4,5, Hitoshi Ishimoto1 (1. Obstetrics and Gynecology, Tokai Univ. School of Medicine, 2. Molecular Life Science, Division of Basic Medical Science, Tokai Univ. School of Medicine, 3. Diagnostic Pathology, Saitama Medical Univ. International Medical Center, 4. Shonan Univ. of Medical Sciences, 5. CHIGASAKI CHUO HOSP. Women's Center Gynecology)
[3P-846]Analysis of the mechanism of promotion of prostate cancer cells proliferation and invasion by adipocyte secretions focusing on cell cycle and cell morphology
○Haruka Takahashi1, Masatoshi Watanabe2, Kazutoshi Iijima3,4 (1. Grad. Sch. Eng. Sci., Yokohama Natl. Univ., 2. Dept. Oncol. Pathol., Sch. Med., Mie Univ., 3. Fac. Eng., Yokohama Natl. Univ., 4. Inst. Adv. Sci., Yokohama Natl. Univ.)
[3P-847]Use of mesenchymal stem cells as tumor-homing cellular carriers for anticancer virus in disseminated cancer models.
○Yuya Takeuchi1,2, Emiko Sonoda-Fukuda2, Nao Ogawa1,2, Noriyuki Kasahara3, Shuji Kubo2 (1. Dept. of Biomed. Chem., Grad. Sch. of Sci. & Tech., Kwansei Gakuin Univ., 2. Lab. of Mol. & Genetic Therap., Advanced Med. Sci., Hyogo Med. Univ., 3. Dept. of Neuro. Surg. & Rad. Oncology, UCSF)
[3P-848]Investigation of a novel anti-cancer virus delivery method using stem cell in peritoneally disseminated models of ovarian cancer
○Nao Ogawa1,2, Yuya Takeuchi1,2, Emiko Sonoda-Fukuda2, Noriyuki Kasahara3, Shuji Kubo2 (1. Dept. of Biomed. Chem., Grad. Sch. of Sci. & Tech., Kwansei Gakuin Univ., 2. Lab. of Mol. & Genetic Therap., Advanced Med. Sci., Hyogo Med. Univ., 3. Dept. of Neuro. Surg. & Rad. Oncology, UCSF)
[3P-849]Identification of synthetic lethal targets for ARID1A-deficient ovarian clear cell carcinoma using the public database DepMap
Ryosuke Saito1, Makoto Fukushima1, Mariko Sasaki1, ○Hideaki Ogiwara1 (1. Natinal Cancer Center Research Institute)
[3P-850]Identification of a Synthetic Lethal Target Based on “Simultaneous Inhibition of a Paralog Pair” Methods in SMARCB1-Deficient Cancers
○Mariko Sasaki1, Daiki Kato2, Karin Murakami2, Hiroshi Yoshida3, Shohei Takase1, Tsuguteru Otsubo2, Hideaki Ogiwara1 (1. Division of Cancer Therapeutics, National Cancer Research Institute, 2. Cancer Research Unit, Sumitomo Pharma Co., Ltd, 3. Department of Diagnostic Pathology, National Cancer Center Hospital)
[3P-851]Establishment of the novel strategy for anti-cancer treatment using ferritinophagy
○Tomohiro Kagi1, Yusuke Hirata1, Takuya Noguchi1, Atsushi Matsuzawa1 (1. Lab. of Health Chem., Grad. Sch. of Pharmaceut. Sci., Tohoku Univ.)
[3P-852]Elucidation of the functional roles of the novel ferroptosis suppressor MKRN1
○Kohei Otani1, Yutaro Yamada1, Yusuke Hirata1, Takuya Noguchi1, Atsushi Matsuzawa1 (1. Lab. of Health Chem., Grad. Sch. of Pharmaceut. Sci., Tohoku Univ.)
[3P-853]Efficient intracellular delivery of PROTAC using cell-penetrating peptides
○Maho Miyamoto1,2, Hidetomo Yokoo2, Yosuke Demizu1,2 (1. Grad. Sch. Med. Life Sci., 2. NIHS)
[3P-854]Analysis of immunological synapse formation by bispecific antibody for treatment of solid tumors
○Rikuto Nakamura1,2, Ryo Tsumura2, Takahiro Anzai2,3, Ryutaro Asano4, Masahiro Yasunaga2 (1. Grad. Sch. of Frontier Sci., Univ. of Tokyo, 2. Div. of Dev. Therap., NCC, 3. Dept. of Chem. & Mater. Sci., Nat. Ins. of Tech., Gunma Col., 4. Dept. of Biotech. & Life Sci., Grad. Sch. of Eng., Tokyo Univ. of Agric. & Tech.)
[3P-855]Preparation of Cancer Cell Surface Vimentin-Specific Liposomes by Using N-Acetylglucosamine Glycopolymers
○Ichiro Miyahara1, Shingo Kobayashi2, Hirohiko Ise2 (1. Department of Applied Chemistry, Graduate School of Engineering, Kyushu Univ., 2. IMCE, Kyushu Univ.)
[3P-856]A simple method to prepare biotinylated Immunoglobulin M from hybridoma culture supernatants
○Tetsuya Okuda1, Katsuya Kato2 (1. BMRI, AIST, 2. AIST Chubu)
[3P-857(3AS-11-05)]Inhibition of ribosome biogenesis in cancer
Rita Ferreira2, Kate Hannan2, Konstantin Panov3, Thejanni Udumanne2, Amee George2, Adria Closa2, Zaka Yuen2, Eduardo Eyras2, Perlita Poh2, Kylee MacLachlan2, Mitchell Dwyer2, Eric Kusnadi1, Richard Rebello1, Alisee Huglo1, Shelley Hedwards1, Mitchell Lawrence1, Gail Risbridger1, Renea Taylor1, Ashlee Clark4, Sharon Pok2, Narci Treon2, Mustapha Haddach5, Denis Drygin5, Ross Hannan2, Nadine Hein2, ○Luc Furic1 (1. Peter Maccallum Cancer Centre, 2. Australian National University, 3. Queen's University Belfast, 4. Monash University, 5. Pimera Inc)
[3P-858]Administration of Nicotinamide Mononucleotide, a Precursor of NAD+, Attenuates Doxorubicin-induced Cardiotoxicity and Renal Injury in Mice.
○Mizuna Miyazaki1, Keiji Saito1, Ryusuke Hosoda1, Yukika Saga1, Yuki Tatekoshi1, Atsushi Kuno1 (1. Sapporo Medical University)
[3P-859]Evaluation of transduction efficiency of in vivo tumors via retroviral vector-producing human mesenchymal stem cells
○Yoshiyuki Yamazaki1, Yuko Nitahara-Kasahara2, Kai Miyazaki3, Yoshitaka Miyagawa1, Takashi Okada2 (1. Dept. of Biochem. and Mol. Bio., Nippon Med. Sch., 2. Div. of Mol. and Med. Genet., Inst. of Med. Sci., Univ. of Tokyo, 3. Dept. of Integ. Diagn. Pathol., Nippon Med. Sch.)
[3P-860]Metformin synergizes with PD-1 blockade to promote normalization of tumor vessels via CD8T cells and IFNγ
○Miho Tokumasu1, Mikako Nishida1, Weiyang Zhao1, Ruoyu Chao1, Natsumi Imano1, Nahoko Yamashita1, Kyoko Hida2, Hisamichi Naito3, Heiichiro Udono1 (1. Okayama Univ., 2. Hokkaido Univ., 3. Kanazawa Univ.)
[3P-861]Evaluation of endothelial-to-mesenchymal transition by lineage analysis of vascular endothelial cells in pancreatic cancer
○Naoki Okamoto1, Keigo Akuta1, Nobuyuki Takakura1 (1. Graduate School of Medicine, Osaka University)
[3P-862]The mechanism of action of IL-18-induced chemokines
○Naoko Yamada1, Nobuyuki Terada1 (1. Hyogo Medical University)
[3P-863]Development of a anticancer drug specific for small cell lung cancer
○Manabu Kodama1, Keiichi Nakayama1 (1. Lab. Anticancer Strategies, Advanced Res. Inst., Inst. Sci. Tokyo)
[3P-864]Anti-tumor effect of nuclear transportable antibody-drug conjugate with Triptolide and live cell imaging assay to evaluate its inhibitory effect against RNA polymerase II
○Mutsumi Hayashi1, Hiroko Madokoro1, Taketo Yamada1 (1. Saitama Medical University)
[3P-865]Development of a 3D stromal co-culture ex vivo model for evaluating the drug efficacy of antibody-drug conjugates in HER2-positive cancer
○Akari Shiraishi1,2, Tomoko Oh-hara1,2, Ryohei Katayama1,2 (1. Div. Experiment. Chemother., Cancer Chemother. Ctr., JFCR, 2. Dept. CBMS, Grad. Sch. Front. Sci., Univ. of Tokyo)
[3P-866]Effect of low-molecular weight fucoidan extract on the inhibitory effect of hyperthermia on cancer cells.
○Keigo Gima1, Hiroshi Eto2, Kiichiro Teruya3 (1. Grad. Sch. Sys. Life Sci., Kyushu Univ., 2. Daiichi Sangyo Co., Ltd., 3. Fac. Agr., Kyushu Univ.)
[3P-867]Alteration of KRAS localization orchestrates MAPK signaling dependency
○Kohei Maruyama1, Satoshi Nagayama3,4, Ryohei Katayama1,2 (1. Div. Exp. Chemother., Cancer Chemother. Ctr., JFCR, 2. Dept. CBMS, Grad. Sch. Front. Sci., The Univ. of Tokyo, 3. Dept. Gastroenterological Surg., Cancer Inst. Hosp., JFCR , 4. Dept. Surgery, Uji-Tokushukai Medical Ctr)
[3P-868]Affinity evaluation of HER2-binding antibodies using antigen/antibody co-expressing cells
○Moe Yamakawa1, Ning Lin1, Takumi Ogawara1, Tetsuya Kadonosono1 (1. School of Life Science and Technology, Tokyo Institute of Technology)
[3P-869]Mechanization of C. elegans behavior analysis for high-throughput cancer detection
○Kazuko Matsubara1, Eric di Luccio1, Takaaki Hirotsu1 (1. HIROTSU BIO SCIENCE)
[3P-870]Prediction of anti-cancer drug combination response using an AI model
○Kohei Ota1,2, Daisuke Koga1, Hirofumi Aso1, Hideyuki Shimizu1,2 (1. TMDU M&D DSC Dept. AI Systems Medicine, 2. Tokyo Medical and Dental University Graduate School)
[3P-871]Clinical utility of microRNA analysis using formalin-fixed, paraffin-embedded colon cancer tissues
○Kenichi Nonaka1,2, Arizumi Kikuchi2, Azumi Naruse2, Kimiaki Takagi3, Yoshifumi Yutoh4, Mitsuhiko Kusakabe1 (1. Daiyukai General Hospital/Surgery, 2. Daiyukai Research Institution for Medical Science, 3. Daiyukai General Hospital/Urology, 4. KANTO CHEMICAL CO.,INC.)
[3P-872]Real-time lung cancer area detection from electron microscope images using deep learning method
○Tatsumi Mizoe1, Kenji Etchuya2, Makiko Suwa1,2, Chikara Sato3 (1. Grad. Biol. Sci., Aoyama Gakuin Univ., 2. Chem. Biol. Sci.,Aoyama Gakuin Univ., 3. National Institute of Advanced Industrial Science and Technology)
[3P-873]Exploring regulatory factors of bone marrow niche remodeling in hematological malignancies using single cell multi-omics analysis
○Yasutaka Hayashi1,2, Masaki Nomura2, Miki Fukumoto2, Weijia Zang2, Yo Mabuchi3, Seiya Mizuno4, Yumi Ito2, Hiromi Yamazaki2, Yui Koike2, Daichi Inoue2, Teppei Shimamura1 (1. Tokyo Medical and Dental University, 2. FBRI, 3. Fujita Health University, 4. University of Tsukuba)
[3P-874]Genomic and epigenomic analysis of lung neuroendocrine carcinoma using long read sequencing technology
○Yoshiki Otsuka1, Junko Zenkoh1, Ryota Matsuoka2, Daisuke Matsubara2, Yutaka Suzuki1, Ayako Suzuki1 (1. Dept. of Comp. Biol. and Med. Sci., Grad. Sch. of Front. Sci., Univ. of Tokyo, 2. Dept. of Diag. Pathol., Inst. of Med., Univ. of Tsukuba)
[3P-875]Development of Biomarkers for Pancreatic Cancer microRNA-based Diagnosis Using Statistical Methods
○Sunao Yotsutsuji1, Masaaki Takada1, Miho Sako1, Yoshitake Sano1, Tomomi Ando1, Mitsuko Sugano1, Hisashi Yamada1 (1. Toshiba Corporation)
[3P-876]Development of a single nucleotide mutation-distinguishable siRNA for PIK3CA (SNPD-siPIK3CA) and verification of its effect on cancer cells
○Toshinori Ohyama1, Yoshiaki Kobayashi2, Yoshimasa Asano2, Susumu Goyama1, Kumiko Ui-Tei1,2 (1. Univ. of Tokyo, GSFS, CBMS, 2. Univ. of Tokyo, GS of Sci., Biol. Sci.)
[3P-877]Development of Therapeutic Strategies Targeting Metabolic Reprogramming Associated with Acquired Drug Resistance in EGFR-Mutant Lung Cancer
○Wataru Nakajima1, Ishino KousukKousuke1,2, Yumi Asano1, Ryuji Ohashi2, Hayashi Yamamoto1 (1. Dept. Mol. Oncl., Inst. Adv. Med. Sci., Nippon Med. Sch. , 2. Dept. Path., Nippon Med. Sch.)
[3P-878]Innovation of NIR luciferin analogues using firefly bioluminescence for in vivo imaging
○Nobuo Kitada1, Genta Kamiya1, Jumpei Hatakeyama1, Ryohei Moriya2, Masahiro Kiyama3, Satoshi Iwano3, Takashi Hirano1, Shojiro Maki1 (1. UEC, 2. JWU, 3. Miyazaki Univ.)
[3P-879]Analysis of type 2 diabetes model ‘pancreatic β cell-specific TSC2 knockout mouse’
○Moe Ohnaka1,2, Ayumi Maeno1,2, Nozomi Kido2, Masako Seike2, Maki Kimura2, Shunichiro Asahara2, Yoshiaki Kido2 (1. Dept.of Metab. and Dis. ,Grad. Sch. of Helth.Sc. , Univ. of Kobe, 2. Dept.of Diab. and Endocrin. ,Grad. Sch. of Med. , Univ. of Kobe)
[3P-880]Mechanism of pancreatic β-cell mass reduction due to constitutive activation of mTORC1
○AYUMI MAENO1,2, Moe Ohnaka1,2, Nozomi Kido2, Masako Seike2, Maki Kimura2, Shunichiro Asahara2, Yoshiaki Kido2 (1. Dept.of Metab. and Dis. ,Grad. Sch. of Helth.Sc. , Univ. of Kobe, 2. Dept.of Diab. and Endocrin. ,Grad. Sch. of Med. , Univ. of Kobe)
[3P-881]AI for predicting enzyme parameters toward a quantitative understanding of metabolic disorders
○Saki Masuda1,2, Satoshi Ohno1, Daisuke Koga1, Yuki Otani1,2, Kohei Ota1,2, Takumi Ito1,3, Hideyuki Shimizu1,2 (1. Dept. AI Systems Medicine, DSC, Tokyo Med. Dent. Univ., 2. Grad. Sch., Med. Dent. Sci., Tokyo Med. Dent. Univ., 3. Sch. Med., Tokyo Med. Dent. Univ.)
[3P-882]Myokine R-spondin 3 regulates Type I fiber determination during skeletal muscle regeneration in mice
○Teng Hu1, Yoshitaka Mita1, Zhu Xinhe1, Furuichi Yasurou1, Manabe Yasuko1, Nobuharu L Fujii1 (1. Tokyo Metropolitan University)
[3P-883]Pathogenesis of atherosclerosis and age-related macular degenerations in a zebrafish model deficient in cholesteryl ester transfer protein CETP
○Kobayashi Haruto1, Nishino Taiki1, Imai Yuta1, Kobayashi Isao2, Sugitani Kayo1, Araiso Yuhei1, Inazu Akihiro1 (1. Dept. of Clin. Lab. Sci., Div. of Health Sci., Kanazawa Univ.,, 2. Fac. of Biological Sci. & Tech., Inst. of Sci. & Eng., Kanazawa Univ.)
[3P-884]Excessive corticosteroid induced mitochondrial dysfunction and cell death in the adrenocortical cells.
○Naohiro Uchida1, Namiko Kawamura1, Aya Fujimoto1, Hironobu Umakoshi1, Tazuru Fukumoto1, Hidenori Iwahashi1, Yoshihiro Ogawa1 (1. Kyushu University)
[3P-885(3PS-04-04)]Downregulation of calcineurin–pyruvate dehydrogenase signaling disrupts energy metabolism in proximal tubule cells and causes kidney fibrosis
○Yasuhiro Oda1, Hiroshi Nishi1, Fumie Hamano2, Teruhiko Yoshida3, Yoshihiro Kita2, Jeffrey B Kopp3, Masaomi Nangaku1 (1. Division of Nephrology and Endocrinology, The University of Tokyo Hospital, 2. Life Sciences Core Facility, The University of Tokyo Graduate School of Medicine, 3. National Institutes of Health)
[3P-886]Coffee diterpenes, cafestol and kahweol, display cytotoxicity and all-trans retinoic acid-induced superoxide generating activity-enhancing ability in U937 cells
○Hidehiko Kikuchi1, Kaori Harata1, Hitomi Mimuro2, Futoshi Kuribayashi3 (1. Shokei Junior College, 2. Oita University, 3. Kawasaki Medical School)
[3P-887(3AS-08-02)]A novel signaling pathway of brown adipocyte activation
○Masaji Sakaguchi1, Shota Okagawa1, Yuma Okubo1, Yuri Takekuma1, Eiichi Araki1, Naoto Kubota1 (1. Faculty of Life Sciences, Kumamoto University)
[3P-888]Physical stimulation in skeletal muscle modulates insulin production via systemic miR-204 induction
Moeka Mukae1, In-Jeoung Baek2, ○Eui-ju Hong1 (1. Chungnam National University, 2. University of Ulsan College of Medicine)
[3P-889(3PS-12-08)]Elucidating the Role of Excretion in Maintaining Nutritional Homeostasis Using Drosophila
○Ayano Oi1,2, Masayuki Miura3, Fumiaki Obata1,2 (1. RIKEN BDR, 2. Kyoto Univ., 3. Univ. Tokyo)
[3P-890]SFPQ maintains skeletal muscle mass through regulating aerobic metabolism
○Motoyasu Hosokawa1, Kei Iida2,5, Jun Tanihata3,4, Shin'ichi Takeda4, Masatoshi Hagiwara5, Akihide Takeuchi1 (1. Ehime University Graduate School of Medicine, 2. Fac. of Sci. and Eng., Kindai Univ., 3. Jikei Univ. Sch. Med., 4. Nat. Inst. Neurosci., Nat. Cent. Neuro. and Psyc., 5. Grad. Sch. Med., Kyoto Univ.)
[3P-891(3PS-12-07)]Elucidation of the physiological negative feedback system controlling alcohol consumption.
○Sho Matsui1, Yuma Takahashi1, Shuhei Morioka1, Yasuo Oguri1, Satoshi Tsuzuki1, Tsutomu Sasaki1 (1. Kyoto University)
[3P-892(3AS-08-06)]Deciphering the Dynamics and Functions of Metabolic Networks from Their Network Structures
○TAKASHI OKADA1, Huang YongJin1, Mochizuki Atsushi1 (1. Kyoto University)
[3P-893]Acetylation of electron transfer flavoprotein alpha is a possible regulatory mechanism of fatty acid oxidation in diabetic hearts
○Masaki Yano1, Yuki Tatekoshi1, Ryusuke Hosoda1, Yukika Saga1, Atsushi Kuno1 (1. Sapporo Medical University)
[3P-894]Insulin-degrading enzyme regulates the activity of the transcriptional coactivator PGC-1α
○Yoshinori Hiraoka1 (1. Kobe Gakuin Univ.)
[3P-895]Mechanism of dopamine receptor-mediated inhibition of insulin secretion by dopamine
○Yusuke Nukui1, Fumiya Uefune1, Daisuke Sakano1, Nobuaki Shiraki1, Shoen Kume1 (1. Science Tokyo)
[3P-896(3PS-12-09)]Effect of dietary protein ratio on metabolic health in young and middle-aged mice
○Maki Takami1, Hitoshi Aoki2, Masato Masuda3, Hiroki Nishi4, Fumihiko Hakuno4, Shin-Ichiro Takahashi4, Takuya Chiba5, Akihito Ishigami1, Yoshitaka Kondo1 (1. Mol. Reg. of Aging, TMIG, 2. Nichirei Foods Inc., 3. Dept. of Info. Sci. and Arts, Toyo Univ., 4. Dept. of Anim. Res. Sci., Grad. Sch. of Agri. and Life Sci., the Univ. of Tokyo, 5. Biomed. Gerontol. Lab., Faculty of Human Sci., Waseda Univ.)
[3P-897]Unraveling the roles of the metabolite sensor CtBP2 in circadian rhythms
○Wanpei Chen1, Motohiro Sekiya1, Kenta Kainoh1, Daichi Yamazaki1, Tomomi Tsuyuzaki1, Yuto Kobari1, Ayumi Nakata1, Ali Majid1, Hitoshi Shimano1 (1. University of Tsukuba, Graduate School of Comprehensive Human Sciences, Department of endocrinology and metabolism)
[3P-898]The comprehensive quantification of Menadione and its conjugates for application as biomarkers in Vitamin K-related diseases
○Shintaro Tagami1, Satoshi Asano1, Miyuu Nishikawa2, Shinichi Ikushiro2, Yoshihisa Hirota1 (1. Drug Discovery Science, Shibaura Institute of Technology, Japan, 2. Faculty of Engineering, Department of Biotechnology, Toyama Prefectural Univ., Japan)
[3P-899]PRMT1 promotes chemoresistance in triple-negative breast cancer by methylating metabolic enzymes PFKFB3, PKM2, and PHGDH to augment de novo fatty acid synthesis.
○Takehiro Yamamoto1, Tetsu Hayashida2, Yohei Masugi3, Mai Itoh1,4, Takako Hishiki1, Chiyoko Nishime4, Naoharu Takano5, Kenichi Horisawa6, Makoto Suematsu1,4 (1. Dept. of Biochem., Sch. of Med., Keio Univ, 2. Dept. of Surg., Sch. of Med., Keio Univ., 3. Dept. of Pathol., Sch. of Med., Keio Univ., 4. Central Institute of Experimental Medicine, 5. Dept. of Biochem., Sch. of Med., Tokyo Medical. Univ., 6. Division of Organogenesis and Regeneration, Medical Institute of Bioregulation, Kyushu University)
[3P-900(3AS-08-07)]Mechanism of age-dependent decline in brown adipose tissue thermogenesis leading to middle-aged obesity
○Manami Oya1, Kazuhiro Nakamura1 (1. Nagoya Univ.)
[3P-901]Physiological Changes in RAW264.7 cells stimulated by AGEs
○Takao Toyomura1, Masahiro Watanabe1, Hidenori Wake2, Takashi Nishinaka2, Omer Faruk Hatipoglu2, Hideo Takahashi2, Masahiro Nishibori3, Shuji Mori1 (1. Shujitsu Univ., 2. Fac. of Med., Kindai Univ., 3. Grad. Sch. of Med., Dent. and Pharm. Sci., Okayama Univ.)
[3P-902]Elucidation of the regulatory hepatic gluconeogenesis mechanism by SIRT7.
○Tomoya Mizumoto1, Yoshifumi Sato1, Tomonori Tsuyama2, Isaac Micallef3, Norie Araki3, Tatsuya Yoshizawa4, Kazuya Yamagata1,2 (1. Medical Biochemistry, Kumamoto Univ., 2. Center for Metabolic Regulation of Healthy Aging, Kumamoto Univ. , 3. Tumor Genetics and Biology, Kumamoto Univ., 4. Cell Biology, Kyoto prefectural University of medicine)
[3P-904]Cricket Consumption Promotes Significant Weight Gain in Low Estrogen Conditions
○Amanda Lisa Sugawara1, Hsiao Hsieh Wang1, Haruka Hosoki1, Toru Asahi1,2,3, Kosuke Kataoka2,4, Chihiro Nozaki5 (1. Waseda Univ., Grad. School of Adv. Sci. & Eng., Dept. of Life Sci. & Med. Biosci., 2. Waseda Univ., Comp. Res. Org., 3. Waseda Univ., Inst. for Nano-Life Innov., 4. Tokyo Univ. of Agr. & Tech., Fac. of Eng., Dept. of Biomed. Sci., 5. Waseda Univ., Fac. of Sci. & Eng., Int'l Center for Sci. & Eng.)
[3P-905]Transitions and Thermodynamics on Species Graphs of Chemical Reaction Networks
○Keisuke Sugie1,2, Dimitri Louchiko2, Tetsuya J Kobayashi1,2 (1. Department of Mathematical Informatics, Graduate School of Information Science and Technology, The University of Tokyo, 2. Institute of Industrial Science, The University of Tokyo)
[3P-906]Influence of amino acid Amadori products on glucose transporter gene expression of chicken embryonic skin-derived fibroblasts
○Kazuki Nakamura1, Kazumi Kita2 (1. Grad. Sch. of Arts and Sciences, Iwate Univ., 2. Fac. Agr, Iwate Univ.)
[3P-907]Regulation of gut starvation response through Drosophila NP3253 neurons
○DAT QUANG NGUYEN1, Kiho Fujii1, Ayane Yagi1, Kentarou Ishibashi1, Naoyuki Fuse1, Shoichiro Kurata1 (1. Molecular Genetics, Grad. Sch. of Pharm. Sci., Tohoku Univ.)
[3P-908]Half-life of amino acid Amadori compounds not present in chicken plasma and the search for chicken plasma-binding proteins.
○Ayasa Masuda1, Kazumi Kita2, Ryousuke Makino2, Tae Sakai2 (1. Graduate School of Arts and Sciences, Iwate University, 2. Faculty of Agriculture, Iwate University)
[3P-909]Molecular Mechanism of Ad4BP/SF-1-Mediated Global Gene Expression through Metabolic Control in Adrenocortical zona fasciculata cells.
○Fumiya Takahashi1, Shogo Yanai2, Keisuke Ishiwata3, Kazuhiko Nakabayashi3, Kenichiro Hata3,4, Tomohiro Ishii5, Tomonobu Hasegawa5, Ken-ichirou Morohashi1,6, Takashi Baba1 (1. Dept. of Mol. Biol., Grad. Sch. of Med. Sci., Kyushu Univ., 2. Dept. of Syst. Life Sci., Grad. Sch. of Syst. Life Sci., Kyushu Univ., 3. NCCHD, 4. Gunma Univ., 5. Keio Univ., 6. Kurume Univ.)
[3P-910]Regulation of gluconeogenesis enzyme gene expression by ornithine
○Wakana Sato1, Nonoka Mitani1, Hiroki Nishi1,2, Mariko Isogai1, Maki Asano1, Akihiro Ito3, Shin-Ichiro Takahashi1, Fumihiko Hakuno1 (1. Tokyo Univ., 2. Saitama Univ., 3. Tokyo University of Pharmacy and Life Sciences)
[3P-911]The Paradox of Aerobic Exercise in Mitochondrial Dysfunction
○Sho Hanada1, Takanaga Shirai2, Kaori Ishikawa3, Tohru Takemasa2, Kazuto Nakada3 (1. Master’s Program in Biology, University of Tsukuba, 2. Institute of Health and Sport Sciences, University of Tsukuba, 3. Institute of Life and Environmental Sciences, University of Tsukuba)
[3P-912]Analysis of a mouse model for Waardenburg syndrome with a spontaneous novel Pax3 mutation
○Daiki Hosomi1,2, Kokoro Furutani1, Takashi Watanabe1, Yuta Ishizuka1, Junko Matsuda1 (1. Dept. Pathophysiol. Metab., Kawasaki Med. Sch., 2. Grad. Sch. Health Sci. Tech., Kawasaki Univ. Med. Welf.)
[3P-913]Generation and characterization of Diamond-Blackfan anemia model cells
○Atomu Uchijo1, Toru Nagayama1, Ryotaro Kawasumi1, Kouji Hirota1, Masato Taoka1 (1. Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University)
[3P-914]Analysis of new Emerin-interacting proteins
○Daisuke Sato1, Hiroaki Nakamura1, Takako Abe1, Taro Mannen1, Toshiya Hayano1 (1. Ritsumeikan Univ)
[3P-915]Searching for the region responsible for poor body weight gain in the mouse Prader-Willi syndrome critical region
○Tatsuya Kishino1 (1. Nagasaki University)
[3P-916]PanelSearch: A web service to support the development of gene panels for the diagnosis of rare diseases
○Jaemoon Shin1, Atsuko Yamaguchi2, Minae Kawashima1, Toyofumi Fujiwara1 (1. Database Center for Life Science, 2. Tokyo City University)
[3P-917]Characterization of coincidentally obtained ataxic mice without causative mutation in the coding region
○Ayaka Eguchi1,2, Satoko Arai1, Toru Miyazaki1 (1. IAM, 2. Fac. of Med., Univ. of Tokyo)
[3P-918]The Mechanism of Autophagy Disruption Caused by LAMP-2 Deletion in Danone Disease
○Tomo Shiota1, Kiichi Nakahira2, Minako Yamaoka1, Mai Makino3, Shuhei Nakamura3,4, Kazuma Sugie1,4 (1. Department of Neurology, Nara medical university, 2. Department of Pharmacology, Nara medical university, 3. Department of Biochemistry, Nara medical university, 4. Center of Autophagy and Anti-Aging Research)
[3P-919]Unraveling the role of dystrophin isoform in astrocytes in Duchenne muscular dystrophy using human cerebral organoids
○China Tatebori1,2, Chaitra Sathyaprakash1, Katsuhiko Kunitake1, Reiko Terada1, Katsura Minegishi1, Yoshitsugu Aoki1 (1. Department of Molecular Therapy, National Center of Neurology and Psychiatry, 2. Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology)
[3P-920]Establishment of a Drosophila model for CMT by neuron-specific knockdown of PNKP
○Hyuga Yoshikawa1, Hideki Yoshida1, Erandika Conthrath1 (1. Kyoto Institute of Technology)
[3P-921]Phenotypic changes of endothelial cells in the pathogenesis of aortic dissection
○Kenichi Kimura1, Eri Motoyama1, Sachiko Kanki2, Keiichi Asano1, Md Al Amin Sheikh1, Violette Deleeuw3, Patrick Sips3, Julie De Backer4, Lynn Y Sakai5, Hiromi Yanagisawa1 (1. University of Tsukuba, 2. Osaka Medical and Pharmaceutical University, 3. Ghent University, 4. Ghent University Hospital, 5. Oregon Health and Science University)
[3P-922(3AS-03-04)]Retrotransposon insertion in the FGFR1 gene is responsible for congenital hypogonadotropic hypogonadism
○Yoko Kuroki1,2,3, Kentaro Sawano4, Erina Suzuki5, Yasuko Ogiwara5, Keisuke Nagasaki4, Maki Fukami3,5 (1. Dept. of Genome medicine, National Center for Child Health and Development, 2. Div. of Collaborative Research, National Center for Child Health and Development, 3. Div. of Diversity Research, National Center for Child Health and Development, 4. Div. of Pediatrics, Dept. of Homeostatic Regulation and Development, Niigata University Graduate School of Medical and Dental Sciences, 5. Dept. of Molecular Endocrinology, National Center for Child Health and Development)
[3P-923]A boy with Beckwith-Wiedemann spectrum showing a 46,XY karyotype caused by genome-wide paternal uniparental heterodisomy
○Satoshi Hara1, Tomohiko Sato2, Musashi Ichimaru1, Hidenobu Soejima1 (1. Saga University, 2. Hirosaki University)
[3P-924]Development of precise single nucleotide genome editing technology for Fibrodysplasia ossificans progressive (FOP) treatment
○Karin Takahashi1, Masaki Kawamata1, Atsushi Suzuki1 (1. Kyushu Univ.)
[3P-925]Genetic diversity of the Japanese people as a clue to find disease-associated genes
○Rise Oyachi1, Aya Takeishi1, Atsuko Shigenari1, Shingo Suzuki1, Takashi Shiina1, Tadashi Imanishi1 (1. Mol Life Sci, Tokai Univ Sch Med)
[3P-926]The transcriptional network that induces cellular morphological changes by the master transcription factor FAMA
○Hikari Kitani1, Makoto Shirakawa1, Toshiro Ito1 (1. Nara Institute of Science and Technology)
[3P-927]Analysis of the downstream gene network of imprinted genes in Arabidopsis thaliana
○Seiu Yamazaki1, Komei Hori1, Ryoko Ebihara1, Tamaki Shitabo1, Keishiro Yamada1, Sho Yamaguchi1, Kei Yamaguchi1, Yuko Wada1, Seiji Takayama2, Toshiro Ito1 (1. Grad. Sch. of. Biol. Sci, NAIST., 2. Grad. Sch. of. Agri. Life Sci. Tokyo Univ.)
[3P-928]Stress-Associated Protein is a potential target of a devernalization inducer, DVR04, in Arabiodopsis
○Sena Harada1, Nana Otsuka1, Makoto Shirakawa1, Toshiro Ito1 (1. Nara Institute of Science and Technology)
[3P-929]Analysis of regulatory mechanism of endosperm development by imprinted genes in Arabidopsis thaliana.
○Yuka Osaka1, Ryoko Ebihara1, Tamaki Shitabo1, Keishiro Yamada1, Yamaguchi Sho1, Yamaguchi Kei1, Wada Yuko1, Takayama Seiji1, Ito Toshiro1 (1. Nara Institute of Science and Technology)
[3P-930]Molecular mechanisms of heat response by HSFA family in Arabidopsis thaliana
○Rin Ishiyama1, Tatsuya Hongo1, Nobutoshi Yamaguchi1, Toshiro Ito1 (1. Nara Institute of science and technology)
[3P-931]Molecular mechanism of isoprene-mediated plant growth and heat response in plants
○Sayaka Okamoto1, Nobutoshi Yamaguchi1, Itoh Toshiro1 (1. NARA INSTITUTE of SCIENCE and TECHNOLOGY)
[3P-932]Transcriptional control of MACCHI-BOU4 gene in Arabidopsis during nectary development
○Ryosuke Ohta1, Makoto Takahashi1, Asumi Nagamori1, Toshiro Ito1, Nobutoshi Yamaguchi1 (1. NARA INSTITUTE of SCIENCE and TECHNOLOGY)
[3P-933]Cloning and expression analysis of blue-light photoreceptor genes in indigo plant, Polygonum tinctorium
○Katsuyuki Miyawaki1,2,3, Kotomi Kawaji2, Tatsuhiro Yoshimoto2, Aruto Somehara3, Akari Yoneda3, Nanoha Tsuruoka3, Aya Nakai1 (1. Tokushima Univ., 2. Tokushima Univ. Front Sci., 3. Tokushima Univ. Bio)
[3P-934]Functional study of Glycine-rich protein in Arabidopsis pollen coat
○Haruki Oguni1, Surachat Tangpranomkorn1, Fumiko Ishizuna2, Siji Takayama1, Sota Fujii1,3 (1. Dept. of Applied Biol. Sci., Grad. Sch., of Agric Life Sci., Univ. of Tokyo, 2. Faculty of Contemporary Human Life Sci., Tokyo Kasei Gakuin Univ., 3. Suntory Rising Stars Encouragement Program in Life Sciences)
[3P-935]Year-round metabolomic analysis of Hevea brasiliensis latex and application to control material properties
○Nobuyuki Hiraoka1,2, Shunsuke Imai2, Shintaro Shioyama2, Fuminori Yoneyama2, Akio Mase2, Yuko Makita1 (1. Maebashi Institute of Technology, 2. Sumitomo Riko Company Limited.)
[3P-936]Predicting the Timing of Dormancy Release in 'Somei-yoshino' Cherry Tree Using Latitudinal Gradients in Molecular Phenology
○Atsuko Miyawaki-Kuwakado1,2, Qingmin Han3, Keiko Kitamura4, Akiko Satake1 (1. Kyushu Univ., 2. JSPS, 3. FFPRI, 4. FFPRI Hokkaido)
[3P-937]Production of a Staphylococcus aureus-specific antimicrobial protein lysostaphin in rice and evaluation of its accumulated amount among different subcellular localization
○Hayato Kayukawa1, So Shimoda1, Hiroshi Yoneyama1, Yukihiro Ito1 (1. Tohoku University)
[3P-938]Recognition mechanism of plant immune inducer EF-Tu by rice receptor-type kinase ERC1
○Hokuto Rikiyama1, Kouki Iba1, Tomohiro Matsuda1, Yuya Katsuragi2, Fang-Sik Che1,2,3 (1. Grad. Sch. of Biosci., Nagahama Inst. of Bio-sci and Tech., 2. Dept. of Bio-sci., Nagahama Inst. of Bio-sci and Tech., 3. GERI, Nagahama Inst. of Bio-sci and Tech.)
[3P-939]Exploration of novel genes involved in interspecies incompatibility in Brassica species
○Tsukasa Matsuura1, Yoshinobu Kato1,2, Kayo Mori1, Seiji Takayama1, Fujii Souta1,3 (1. Dept. of Applied Biol. Sci., Grad. Sch., of Agric Life Sci., Univ. of Tokyo, 2. Precursory Research for Embryonic Science and Technology, 3. Suntory Rising Stars Encouragement Program in Life Sciences)
[3P-940]Analysis of Mechanism for Colony Formation in Botryococcus, Freshwater Colonial Green Microalgae
○Takuya Aoyanagi1, Haruki Yoshino1, Yusaku Nishio1, Takayuki Marutani1 (1. Institute of Microalgal Technology, Japan)
[3P-941]Regulatory mechanisms of lipid composition induced by changes in nutrient concentrations in Chlamydomonas
○Yusaku Nishio1, Haruki Yoshino1, Takuya Aoyanagi1, Takayuki Marutani1 (1. Institute of Microalgal Technology, Japan (IMAT))
[3P-942]Construction and utilization of agrobacterium infiltration-type tomato mosaic virus-derived virus vector expressing human Caspase-3 gene.
○Yuta Yamagishi1, Yuki Fujii2, Nobumitsu Sasaki1,2,3, Yasuhiko Matsushita1,2,3 (1. Grad. Sch. of Agr. Sci., Tokyo Univ. of Agr. & Tech., 2. United Grad. Sch. of Agr. Sci., Tokyo Univ. of Agr. & Tech., 3. Gene Res. Center, Tokyo Univ. of Agr. & Tech.)
[3P-943]Ectopic expression of the gene encoding a tobacco ethylene response factor NtERF#206 suppresses potato virus X infection.
○kaisei kaneko1, Nobumitsu Sasaki1,2, Yasuhiko Matsushita1,2 (1. Grad. Sch. of Agr. Sci., Tokyo Univ. of Agr. & Tech., 2. Gene Res. Center, Tokyo Univ. of Agr. & Tech.)
[3P-944]Genomic analysis of two quinoa inbred lines from northern and southern highlands of Altiplano where quinoa originated
○Yasufumi Kobayashi1, Hideki Hirakawa2, Kenta Shirasawa2, Kazusa Nishimura3, Kenichiro Fujii1, Rolando Oros4, Giovanna R. Almanza5, Yukari Nagatoshi1, Yasuo Yasui6, Yasunari Fujita7,8 (1. Biological Resources and Post-harvest Division, Japan International Research Center for Agricultural Sciences, 2. Kazusa DNA Research Institute, 3. Graduate School of Environmental, Life, Natural Science and Technology, Okayama University, 4. Fundación PROINPA, 5. Universidad Mayor de San Andres, 6. Graduate School of Agriculture, Kyoto University, 7. Food Program, Japan International Research Center for Agricultural Sciences, 8. Graduate School of Life Environmental Science, University of Tsukuba)
[3P-945]Do epidermal bladder cells play a role in water retention in quinoa leaves?
Yasufumi Kobayashi1, ○Yasunari Fujita2,3 (1. Biological Resources and Post-harvest Division, Japan International Research Center for Agricultural Sciences, 2. Food Program, Japan International Research Center for Agricultural Sciences, 3. Graduate School of Life Environmental Science, University of Tsukuba)
[3P-946]Development of an Automated Tool for Drug Repositioning Based on Disease-Specific Gene Expression Data
○Yi Cong1, Naoki Osada1, Toshinori Endo1 (1. Hokkaido Univ.)
[3P-947]Sulfhydrated Albumin Transmits H2S Signal and Ameliorates APAP-Induced Liver Injury
○Yijun Xu1, Xin Wang1, Jian Yao1 (1. University of Yamanashi)
[3P-948]Development of two Cre-dependent luciferase mouse strains with distinct emission spectra
○Toshiaki Nakashiba1, Katsunori Ogoh2, Satoshi Iwano3,5, Takashi Sugiyama2, Saori Mizuno1, Kenichi Nakashima1, Seiya Mizuno4, Fumihiro Sugiyama4, Atsushi Yoshiki1, Atsushi Miyawaki5, Kuniya Abe1 (1. RIKEN BRC, 2. Olympus Corporation, 3. Miyazaki University, 4. University of Tsukuba, 5. RIKEN CBS)
[3P-949]The role of uPAR in vascular dysfunction
○Yosuke Kanno1, Osamu Matsuo2, Kei-ichi Ozaki1 (1. Doshisha Women’s College of Liberal Arts, 2. Kindai University)
[3P-950]descSPIM-Advanced: A Highly Optimized DIY Compact Light Sheet Microscopy for Tissue Clearing Users
○Yuki Nozawa1, Kohei Otomo1,2,3,4,5, Etsuo A Susaki1,2,3,6 (1. Dept. Biochem. II, Juntendo Univ. Sch. Med., 2. DBSB, Juntendo Univ. Grad. Sch. Med., 3. Nakatani BSH, Juntendo Univ. Grad. Sch. Med., 4. Dept. Biophoton., NIPS, NINS, 5. Biophoton. Res. G., ExCELLS, NINS, 6. Inst. Quantum Life Sci., QST)
[3P-951]QuickConc: A rapid and efficient eDNA concentration method applicable to diverse aquatic environments
○Ryo Iwamoto1, Tomohiro Kuroita1, Qianqian Wu2, Toshifumi Minamoto2 (1. AdvanSentinel Inc., 2. Kobe Univ.)
[3P-952]The exploration of novel predictive blood factor for atopic dermatitis in NC/Nga mice
○Yoshie UMEHARA1, Arisa Ikeda2, Ko Okumura1, François Niyonsaba1,3 (1. Atopy (Allergy) Research Center, Juntendo Univ. Grad. Sch. of Med., 2. Dept. of Dermatol., Juntendo Univ. Grad. Sch. of Med., 3. Faculty of International Liberal Arts, Univ. of Juntendo)
[3P-953]Functional analysis of infertility-associated gene with genome editing mice.
Mayumi Kohno1, ○Hiroaki Hiramatsu1, Masumi Namba1, Tomoe Kobayashi1, Junko Otsuki2, Makoto Matsuyama1 (1. Division of Molecular Genetics, Shigei Medical Reserch Institute, 2. Graduate of Health Science, Okayama University)
[3P-954]Cutting-Edge Cancer Screening with Caenorhabditis elegans
○Umbhorn Ungkulpasvich Ungkulpasvich1, Eric di Luccio1, Takaaki Hirotsu1 (1. Hirotsu Bio Science, Japan)
[3P-955]Development of a chemical structure-based method for discovering secondary metabolites of microbes using LC-Raman
○Takuma Kyotani1, Takuji Nakashima2, Masahiro Ando2,3, Haruko Takeyama1,2,3,4 (1. Grad. Sch. Adv. Sci. Eng., Waseda Univ., 2. Res. Org. Nano Life Innov., Waseda Univ., 3. CBBD-OIL, AIST-Waseda Univ., 4. Inst. Adv. Res. Biosyst. Dyn., Waseda Res. Inst. Sci. Eng., Waseda Univ.)
[3P-956]Abnormal processing and intramuscular localization of Calpain 3 associated with Limb-Girdle Muscular Dystrophy R1
○Chihiro Hisatsune1, Fumiko Shinkai Ouchi1, Shoji Hata1, Yasuko Ono1 (1. Tokyo Metropolitan Institute of Medical Science)
[3P-957]Role of Ultraviolet C irradiation in wound healing and tissue regeneration
○Liqing Zang1, Hideto Miyake2, Yasuhitp Shimada3, Norihiro Nishimura1 (1. Graduate School of Regional Innovation Studies, Mie University, 2. Graduate School of Engineering, Mie University, 3. Department of Integrative Pharmacology, Mie University Graduate School of Medicine)
[3P-958]Update of the Mouse Genome variation Database MoG+
○Toyoyuki Takada1, Daiki Usuda1, Tatsuya Kushida1, Hiroshi Masuya1 (1. RIKEN BioResource Research Center)
[3P-959]Modeling Fibro-Fatty Replacement in Arrhythmogenic Cardiomyopathy Using iPS Cells
○Noa Miwa1, Yutaro Miyoshi1, Ryo Niwa1, Tomoko Matsumoto1, Xiaoyan Ren1, Knut Woltjen1, Shunsuke Funakoshi1, Yoshinori Yoshida1 (1. Kyoto University, Ctr. for iPS cell res. appl.(CiRA))
[3P-960]Analysis of novel liver fibrosis-associated factors expressed in activated hepatic stellate cells
○Marie Kijima1, Kazuko Kanegae1, Yu Arimasu1, Hitoshi Okochi1, Hiroyasu Nakano2, Minoru Tanaka1 (1. NCGM, 2. Toho Univ.)
[3P-961]Effect of Novel Antimicrobial Peptides on Intestinal microbiota in Necrotizing Enteritis in Broilers
○Yi-Bing Horng1, Wei-Jung Chen1 (1. National Ilan university)
[3P-962]Investigation of the biological effects of repeated oral exposure to titanium dioxide nanoparticles in rats
○Jun-ichi Akagi1, Yasuko Mizuta1, Mizuho Uneyama1, Hirotoshi Akane1, Kohei Matsushita1, Takeshi Toyoda1, Kumiko Ogawa1 (1. Div. Pathology, Natl. Inst. Health Sci.)
[3P-963]Molecular insights into osteoporosis induced by physical inactivity
○Kei Gochi1,2, Eriko Sumiya3, Naoyoshi Sakitani4, Yoshiki Otsuka5, Masafumi Muratani6, Shinichiro Sawa7, Hiroki Ochi2, Yasuhiro Sawada8, Ken-ichi Nakahama1, Masahiro Shinohara2 (1. Department of Cellular Physiological Chemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 2. Department of Rehabilitation for Motor Functions, National Rehabilitation Center for Persons with Disabilities, 3. Department of Orthopedic Surgery, Faculty of Medicine, University of Tokyo, 4. Department of Life Science and Biotechnology, National Institute of Advanced Industrial Science and Technology, 5. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, 6. Department of Genome Biology, Institute of Medicine, University of Tsukuba, 7. Division of Mucosal Immunology, Medical Institute of Bioregulation, Kyushu University, 8. Department of Clinical Research, National Rehabilitation Center for Persons with Disabilities)
[3P-964]Breed improvement of chickens using genome editing technology
○Ryo Ezaki1, Tenkai Watanabe1,2, Takumi Terada1, Mei Matsuzaki1, Hidemasa Bono1,2, Takashi Yamamoto1,2, Hiroyuki Horiuchi1,2 (1. Graduate School of Integrated Sciences for Life, Hiroshima University , 2. Hiroshima University Genome Editing Innovation Center)
[3P-965]SIRT1 activation by resveratrol ameliorates doxorubicin-induced skeletal muscle atrophy in mice
○Reika Iwafune1, Ryusuke Hosoda1, Ryuta Nakashima1, Naotoshi Iwahara2, Iyori Nojima1, Atsushi Kuno1 (1. Department of Pharmacology, Sapporo Medical Univ School of Medicine, 2. Department of Neurology, Sapporo Medical Univ School of Medicine)
[3P-966]Possible ameliorative effects of indole-3-acetic acid on DSS-induced colitis and associated acute kidney injury focusing on plasma iron concentration
○Chihiro Takei1, Ayame Tomii1, Keisuke Yoshikiyo1, Hidehisa Shimizu1 (1. Grad. Sch. Nat. Sci. Tech, Shimane Univ.)
[3P-967]Mechanical stimulation-induced angiogenesis in retinal pigment epithelial cells and its molecular mechanisms
○Atsushige Ashimori1, Fumiaki FumiakiHigasijima1, Tadahiko Ogata1, Ayano Sakuma1, Waka Hamada1, Jyunki Sunada1, Ren Aoki1, Masatoshi Mikuni1, Takuya Yoshimoto1, Kenichiro Hayashi1, Makiko Wakuta1, Kazuhiro Kimura1 (1. Department of Ophthalmology, Yamaguchi Univ.)
[3P-968]The roles of Y chromosomal genes in mouse sex spectrum phenotypes
○Nobuhiko Tanaka1, Kento Miura3, Ai Ozaki2, Yasuyo Kozawa2, Masaru Tamura2, Atsuo Ogura2,4,5, Shogo Matoba2 (1. Shimonoseki City Univ., 2. RIKEN BRC, 3. Hiroshima Univ., 4. Tsukuba Univ., 5. RIKEN CPR)
[3P-969]Novel Pathogenesis of Diamond-Blackfan Anemia Explored Through Regulation of Proteostasis
○Tatsuya Yamakawa1, Chiaki Yoshino1, Nishimura Rika1, Megumi Kumazaki1, Tsuyoshi Tabata2, Megumu Saito1, Mio Iwasaki1 (1. Center for iPS Cell Research and Application, Kyoto Univ., 2. MassSoft)
[3P-970]Establishing Garra rufa as a novel cyprinid model for human disease with high-temperature tolerance
○Misa Nakai1, Kiki Syaputri Handayani2, Koto Kon-Nanjo3, Victor David Gultom2, Oleg Simakov3, Fahrurrozi _2, Tetsuo Kon3, Yasuhito Shimada4,5 (1. Mie Univ. Regio, 2. BRIN, 3. Vienna Univ., 4. Mie Univ. Pharmacol, 5. Mie Univ. Zerba)
[3P-971]Detection of VBNC state Vibrio cholerae from sewage and environmental waters.
○Ayumu Ohno1,2, Priyanka Denny1, Debmalya Mitra1, Goutam Chowdhury4, Kei Kitahara1,2, Suman Kanungo4, Shanta Dutta4, Asish Mukhopadhyay4, Shin-ichi Miyoshi2,3 (1. Collaborative Research Centre of Okayama University for Infectious Diseases in India, 2. Research Center for Intestinal Health Science, Okayama Univ., 3. Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ., 4. ICMR-NIRBI)
[3P-972]Investigation of microfluidic devices suitable for co-culture of human iPSCs-derived neurons.
○Yuta Murakami1, Bingbing Wang1, Keiko Nishijima2, Asako Otomo2,3, Shinji Hadano2,3, Hiroshi Kimura1,3 (1. Dept. of Mech., Tokai Univ. Sch. Eng., 2. Dept. of Physiol., Tokai Univ. Sch. Med., 3. MNTC, Tokai Univ.)
[3P-973]Examining the effect of plant-derived ingredients on AGEs suppression
○Takanori Matsui1 (1. Fukui Prefectural University)
[3P-974]Hexanucleotide repeat expansion in SCA36 reduces the expression of genes involved in ribosome biosynthesis and protein translation
○Yinrui Sun1, Takuya Morikawa1, Shiroh Miura2, Yusuke Uchiyama3, Shigeyoshi Hiruki1, Ryuta Fujioka4, Hiroki Shibata1 (1. Division of Genomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan, 2. Department of Neurology and Geriatric Medicine, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, Japan, 3. Department of Radiology, Kurume University School of Medicine, Kurume, Fukuoka, Japan, 4. Department of Food and Nutrition, Beppu University Junior College, Kitaishigaki, Oita, Japan)