The 145th Annual Meeting of the Pharmaceutical Society of Japan (Fukuoka)

[28P-pm001S]Synthetic Studies of fused Tricyclic Pyrazolo[3,4-b]pyridine Derivatives (2).

Fumi Okabe-Nakahara¹, ○Neiro Kubo¹, Nanako Shimizu¹, Ayano Kabu¹, Ayaka Ide¹, Takafumi Fujita¹, Eiichi Masumoto¹, Hiroshi Maruoka¹
(1. Fac. Pharm. Sci., Fukuoka Univ.)

[28P-pm002S]Synthetic Studies of fused Tricyclic Naphthyridine Derivatives.

Fumi Okabe-Nakahara¹, ○Kohei Ando¹, Takafumi Fujita¹, Eiichi Masumoto¹, Hiroshi Maruoka¹
(1. Fac. Pharm. Sci., Fukuoka Univ.)

[28P-pm003S]Synthetic study on rubioncolin B

○Takaaki Aijima¹, Shuji Akai¹, Yoshinari Sawama¹
(1. Grad. Sch. Pharm. Sci., Osaka Univ.)

[28P-pm004]Synthetic Study of Sigillins

Yousuke Yamaoka¹, ○Mimona Abe¹, Hideto Miyabe¹
(1. Sch. of Pharm. Hyogo Med. Univ.)

[28P-pm005]Synthesis of cycloheptatriene annulated silacycles via intramolecular cyclization of silyldiazomethanes

○Yutaro Hanatani¹, Ryuma Ohchi², Tsuyoshi Matsuzaki³, Takeyuki Suzuki³, Mitsuhiro Arisawa², Kenichi Murai^1,2
(1. School of Pharmaceutical Science, Wakayama Medical University, 2. Graduate School of Pharmaceutical Sciences, The University of Osaka, 3. SANKEN, The University of Osaka)

[28P-pm006S]Synthetic studies of spiro-furanone-pyrazolone derivatives by a three-component reaction

○Mashiro Matsuo¹, Kaho Urabe¹, Takafumi Fujita¹, Fumi Okabe-Nakahara¹, Hiroshi Maruoka¹, Eiichi Masumoto¹
(1. Fac. Pharm. Sci., Fukuoka Univ.)

[28P-pm007S]Partial synthesis of the unnatural amino acid component of cycloimidamicin A, a novel antimicrobial natural product

○Makiko Komagata^1,2, Hikaru Abe², Chiharu Sakashita², Yoshimasa Ishizaki², Masayuki Igarashi², Takumi Watanabe², Masakatsu Shibasaki²
(1. Grad. Sch. Biochem. Sci., Keio Univ., 2. Institute of Microbial Chemistry)

[28P-pm008S]Phosphazene base-catalyzed intramolecular addition of enolates to alkenes

○Honoka Nodao¹, Saki Nikaido¹, Kenji Watanabe¹, Hideyasu China¹, Junpei Matsuoka², Yasutomo Yamamoto¹
(1. Doshisha Women's College of Liberal Arts, 2. Kindai University)

[28P-pm009S]Synthesis of partial fluorinated compounds containing
γ,γ’,γ’’-trifluoroneopentyl group via Sonogashira-coupling reaction

○Shouta Miyake¹, Atsushi Tarui¹, Shoki Hoshikawa¹, Yukiko Karuo¹, Kazuyuki Sato¹, Kentaro Kawai¹, David O’Hagan², Masaaki Omote¹
(1. Pharm. Sci., Setsunan Univ., 2. Univ. St Andrews)

[28P-pm010]Synthesis and Biological Activity Evaluation of Gnetin C Derivatives: Development of Novel Polyphenols via Site-Selective Deacetylation

○Ayumi Kirii¹, Akiho Yagi¹, Ryuji Uchida¹, Takafumi Hayashi¹, Shinobu Sakurada¹, Yuichi Ohkawara², Koichi Narita¹, Kazuhiro Watanabe¹
(1. Fac. Pharm. Sci., Tohoku Med. Pharm. Univ., 2. Tohoku Med. Pharm. Univ. Wakabayashi HP)

[28P-pm011S]Ring expansion of spirocyclopropanes using potassium cyanate

○Ryuichiro Inaba¹, Hitomi Noro¹, Keisuke Tomohara¹, Hisanori Nambu¹
(1. Kyoto Pharm. Univ.)

[28P-pm012]Synthesis of DMAP-type planar-chiral pyridinophanes and their applications

○Ken-ichi Iwamoto¹, Shunsuke Warashina¹, Kei Manabe¹
(1. University of Shizuoka)

[28P-pm013S]Synthesis and Spectroscopic Properties of Photo Responsive Porphyrin-Pyrene Hybrid Molecules

○Misa Taketani¹, Satoshi Hayashi¹, Masahiro Noji¹
(1. Meiji Pharmaceutical Univ.)

[28P-pm014S]Electrogenerated Acid-Catalyzed Dehydrative Etherification of Benzyl Alchols

○Shuntarou Sasaki¹, Yuki Nakayama¹, Satoshi Hayashi¹, Masahiro Noji¹
(1. Meiji Pharmaceutical Univ.)

[28P-pm015]Synthetic study on Palmerolide A

○Makoto Inai¹, Kanta Ito¹, Akinori Kawanishi¹, Asahi Yamashita¹, Toshiyuki Kan¹, Yoshitaka Hamashima¹
(1. Sch. Pharm. Sci., Univ. of Shizuoka)

[28P-pm016S]Design and Synthesis of Unnatural Terpenoid Skeletons using a structure generator

○Kotaro Murayama¹, Takehiro Nishimura¹, Haruhisa Kikuchi¹
(1. Fac. Pharm., Keio Univ.)

[28P-pm017S]Synthetic Studies of Conformationally Restricted Tunicamycin V Derivatives

○Mai Miura¹, Akari Yasuoka², Kazuki Yamamoto², Satoshi Ichikawa²
(1. Fac. of Pharm. Sci., Hokkaido Univ., 2. Grad. Sch. Pharm. Sci., Hokkaido Univ.)

[28P-pm018S]Enantioselective construction of cyclic ketones bearing β,β-diaryl quaternary stereocenters by catalytic asymmetric conjugate addition using a chiral phenanthroline-Pd complex

○Shion Murata¹, Masafumi Tamura¹
(1. Faculty of Pharmaceutical Sciences, Sanyo-Onoda City University.)

[28P-pm019S]Enantioselective construction of 3,3-disubstituted γ-butyrolactone by catalytic asymmetric conjugate addition using a chiral phenanthroline-Pd complex

○Riho Takekiyo¹, Masafumi Tamura¹
(1. Faculty of Pharmaceutical Sciences, Sanyo-Onoda City University.)

[28P-pm020S]Synthesis of 4-alkenylquinolines using dehydrative/decarboxylative cross-coupling reaction in water.

○Matoi Narita¹, En Kenmochi¹, Shoko Kikkawa¹, Isao Azumaya¹, Hidemasa Hikawa¹
(1. Fac. Pharm. Sci., Toho Univ.)

[28P-pm021S]A water-soluble Pd-catalyzed coupling strategy for biimidazopyridine synthesis in water.

○masakazu kobayasi¹, Nanoka Kobori¹, Tomokatsu Enda¹, Shoko Kikkawa¹, Isao Azumaya¹, Hidemasa Hikawa¹
(1. Fac. Pharm. Sci., Toho Univ.)

[28P-pm022S]Construction of purine skeleton via Pd-catalyzed dehydrogenative oxidation of benzyl alcohol in water.

○Tsuzumi Chiba¹, Nanoka Kobori¹, Masakazu Kobayashi¹, Tomokatsu Enda¹, Shoko Kikkawa¹, Isao Azumaya¹, Hidemasa Hikawa¹
(1. Fac. Pharm. Sci., Toho Univ.)

[28P-pm023S]Development of a synthesis of phenanthridinone skeletons using nickel reagents and its application to the synthesis of π-conjugated molecules

○Miyu Sakai¹, Hisato Takahashi¹, Shoko Kikkawa¹, Hidemasa Hikawa¹, Isao Azumaya¹
(1. Fac. Pharm. Sci., Toho Univ.)

[28P-pm024S]Development of metal-free coupling reactions with diazine N-oxides

Ryo Tsunokawa¹, ○Satoshi Fujimoto¹, Shota Sato¹, Shoki Hoshikawa¹, Yukiko Karuo¹, Atsushi Tarui¹, Kazuyuki Sato¹, Kentaro Kawai¹, Masaaki Omote¹
(1. Faculty of Pharmaceutical Sciences, Setsunan University)

[28P-pm025S]Introduction of carbon nucleophiles onto fluorinated isoxazolines at C5 position via C-F bond cleavage.

○Kosei Sotani¹
(1. Faculty of Pharmaceutical Sciences, Setsunan University)

[28P-pm026S]Development of a novel synthesis for difluoro-β-ketoamides based on the ring-opening and rearrangement reaction of isoxazoles

○Yukine Kitamura¹, Kazuyuki Sato¹, Shoki Hoshikawa¹, Yukiko Karuo¹, Atsushi Tarui¹, Kentaro Kawai¹, Masaaki Omote¹
(1. Pharm. Sci., Setsunan Univ.)

[28P-pm027S]Racemization of tertiary alcohols, 3-hydroxy-2-oxindole derivatives, in Pickering emulsion

○Jihoon Moon¹, Shuji Akai¹, Kyohei Kanomata¹
(1. Grad. Sch. Pharm. Sci., Osaka Univ.)

[28P-pm028S]Chiral C₂-symmetric phenanthroline ligands: ligands development and application in Cu-catalyzed asymmetric allylic oxidation

○Yuki Nishihara¹, Tatsuya Kimura, Masafumi Tamura¹
(1. Faculty of Pharmaceutical Sciences, Sanyo-Onoda City University.)

[28P-pm029S]Development of asymmetric organocatalysts with 1,2-diamine framework derived from indane skeleton -the relationship of the position of functional group and catalytic activity-

○Resshi Honda¹, Yuki Yamada¹, Naoki Kawakami¹, Takuro Yasuyama¹, Hirofumi Matsunaga¹
(1. Fac. Pharm. Sci., Sanyo-Onoda Univ.)

[28P-pm030S]Investigation of Pd-catalyzed introduction of phosphorus atoms into terminal alkenes

○Moe Tanaka¹, Yasuhiro Nishikawa¹, Sayaka Suzuki¹, Junnosuke Mase¹, Osamu Hara¹
(1. Faculty of Pharmacy, Meijo University)

[28P-pm031]Hypervalent iodine-catalyzed oxidative C(sp³)–N bond construction for the synthesis of δ-lactam derivatives

○Hirotaka Sasa¹, Miki Okada¹, Manaka Tanigawa¹, Tomoka Higuchi¹, Maaya Nobata¹, Takuya Matsumoto¹, Minoru Ozeki¹, Toshifumi Dohi², Ikuo Kawasaki¹
(1. Department of Pharmacy, Mukogawa Women's University, 2. College of Pharmaceutical Sciences, Ritsumeikan University)

[28P-pm032S]Development of oxidative esterification of cyclic acetals using sulfur compounds and NBS

Junpei Matsuoka¹, ○Yukinori Hayashi¹, Ami Makimura¹, Ayana Tagashira¹, Tomohiro Maegawa¹
(1. School of Pharmaceutical Sciences, Kindai University)

[28P-pm033S]Disulfide bond formation via methoxytrityl group oxidation using photoredox catalysis

○Keita Yamazaki¹, Tetsuhiro Nemoto¹
(1. Grad.Sch.Pharm.Sci., Chiba Univ.)

[28P-pm034S]Development of catalytic γ-position-selective formal aldol condensation reactions of β-ketophosphonates with aldehydes to afford γ,δ-unsaturated β-ketophosphonates

○James Osborne¹, Fujie Tanaka¹
(1. Okinawa Institute of Science and Technology Graduate University)

[28P-pm035S]Photocatalytic deuteration of α-oxy-C(sp3)-H bond of ethers

○Keisuke Matsuura¹, Riku Ogasahara², Shuji Akai², Yoshinari Sawama^2,3
(1. Sch. Pharm. Sci., Osaka Univ., 2. Grad. Sch. Pharm. Sci., Osaka Univ., 3. Kyoto Univ. CPiER-DSR)

[28P-pm036]Bi-directional nitroaldol reaction -Studies using aromatic aldehyde-

○Erika Iwasaki¹, Yusuke Akagi¹, Toshiya Komatsu¹
(1. Fac. Pharm. Sci., Teikyo Heisei Univ.)

[28P-pm037]Study of photomethyl esterification at low temperature using optical fiber

○kiyofumi wanibuchi¹, mitsuru shoji¹
(1. Yokohama Univ. Pharm.)

[28P-pm038]Metal-free carbonylation of secondary benzyl alcohols using air and V-70

○Yamato Kato¹, Hina Kobayashi², Takayuki Shioiri^1,2, Masato Matsugi^1,2
(1. Grad. Sch. Agric., Meijo Univ., 2. Fac. Agric., Meijo Univ.)

[28P-pm039]Synthetic studies of libraries of polymers and assays for their anticancer effects.

○Satomi Niwayama¹, Tatiana Barsukova¹, Dileep Kommula¹
(1. Muroran Institute of Technology)

[28P-pm040S]Functional peptides hybridized with water soluble polymers for high sensitive virus detection

○Ayano Yoshida¹, Noriyuki Uchida¹, Takahiro Muraoka^1,2
(1. Tokyo Univ. Agri. and Tech., 2. KISTEC)

[28P-pm041]Exploring the chemical diversity of Penicillium sclerotiorum through OSMAC approaches

○Yuan-Bin Cheng¹, Tzu-Yi Ke¹, Zheng-Yu Lin¹, Pei-Ting Chiang¹, Shih-Wei Wang², I-Chi Hsu³
(1. Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 80424, Taiwan, 2. Institute of Biomedical Sciences, MacKay Medical College, New Taipei City 25245, Taiwan, 3. Division of Pharmacy, Zuoying Armed Forces General Hospital, Kaohsiung 813204, Taiwan)

[28P-pm042]The chemical structures of the symmetrical fused pyranopyran derivatives produced from a driftwood-derived fungus

○Takeshi Yamada¹, Narumi Kusaka¹, Takashi Kikuchi², Tomoya Hirano¹
(1. Fac. Pharm. Osaka Med. Pharm. Univ., 2. Fac. Pharm. Toho Univ.)

[28P-pm043S]Environmental Analysis of the Medicinal Plant Sinomenium acutum: Prediction of Potential Distribution and Characterization of Environmental Variables Using Maximum Entropy Modeling

○Kaito Kikuchi¹, Suzuka Hokazono¹, Taichi Fujii², Motoyasu Minami², Kaori Iwano³, Katsunori Miyake⁴, Tadahiro Yahagi⁵, Mikiyo Wada⁶, Akihito Takano⁷, Toshiyuki Atsumi¹
(1. Sch. Pharm. Sci., Kyushu Univ. of Medical Science, 2. College of Bioscience and Biotechnology, Chubu Univ, 3. Shikoku Shoyaku, 4. Sch. Pharm. Sci., Tokyo Univ. of Pharm. and Life Sci., 5. Sch. Pharm. Sci., Nihon Univ., 6. Grad. Sch. Pharm. Sci., Kumamoto Univ., 7. Showa Pharm. Univ.)

[28P-pm044]Molecular network analysis of the secondary metabolites of Plukenetia volubilis fruits

○Hao-Ze Li¹, Pei-Hung Chang¹, Tsong-Long Hwang^2,3, Ping-Chung Kuo¹
(1. School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan, Taiwan, 2. Research Center for Chinese Herbal Medicine and Graduate Institute of Healthy Industry Technology, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan, Taiwan, 3. Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan)

[28P-pm045][Withdrawn]

[28P-pm046]Synthesis of ACE inhibitory compound isolated from Monostroma nitidum

○Yuichi Kusaka¹, Yui Asano¹, Kotone Wauke¹, Yoshinori Asakawa¹, Hirofumi Yamamoto¹
(1. Faculty of pharmaceutical Sciences, Tokushima)

[28P-pm047]Study of the effects of semisynthetic cinnamic acid glycosides and active dipeptides on uric acid levels in alternative experimental animals(1)

Akihito Ikeda¹, Eisuke Miyazaki¹, Sayaka Tanibuchi¹, Sayaka Yamamoto², Takao Ohashi², ○Ryuichiro Tanaka¹
(1. Faculty of Pharmaceutical Sciences, Setsunan University, 2. Faculty of Sciences and Technology, Setsunan University)

[28P-pm048]Briarane Diterpenes from Briareum stechei: Potential Anti-Inflammatory Agents from Closed Aquaculture Systems

○Lo-Yun Chen¹, Bo-Rong Peng², Huynh Hao Thanh ², Tsong-Long Hwang², Kuei-Hung Lai^1,3
(1. PhD Program in Clinical Drug Development of Herbal Medicine, College of Pharmacy, Taipei Medical University, 2. Research Center for Chinese Herbal Medicine, College of Human Ecology, Chang Gung University of Science and Technology, 3. Graduate Institute of Pharmacognosy, College of Pharmacy, Taipei Medical University)

[28P-pm049]Compositional research on golden oyster mushrooms

○kazuki watanabe¹, mamoru fukuchi¹, satoshi matsumoto²
(1. Fac. of Pharm., Takasaki Univ. of Hlth. & Welfare, 2. LS Corporation Co., Ltd)

[28P-pm050]Constituents in green perilla suppress production of nitric oxide

○Yukinobu Ikeya¹, Keita Minamisaka², Jun Takanari³, Kazutaka Koga¹, Takaaki Komatsu¹, Mikio Nishizawa²
(1. Daiichi University of Pharmacy, 2. College of Life Sciences, Ritsumeikan University, 3. Amino Up Co., Ltd.)