[29P] Absorption/Transpoters/Distribution and excretion · Metabolism/ADME, PK/PD, Drug interaction

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[29PB-213S] Comparison of inhibitory kinetics of vonoprazan on the metabolic activation of clopidogrel among CYP2C19 variants

○Kohei Ouchi¹, Norika Shimada¹, Hiroyuki Seki², Ayuko Imaoka^1,3, Miyuki Shimoji⁴, Katsunori Nakamura⁴, Hiroshi Yamazaki⁵, Takeshi Akiyoshi^1,3, Hisakazu Ohtani^1,3,6 (1. Fac. Pharm., Keio Univ., 2. Dept. Pharm., Tsukuba Univ. Hosp. , 3. Sch. Med., Keio Univ., 4. Dept. Pharm., Ryukyu Univ. Hosp., 5. Sch. Pharm., Showa Pharmaceutical Univ., 6. Dept. Pharm., Keio Univ. Hosp.)

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