The 145th Annual Meeting of the Pharmaceutical Society of Japan (Fukuoka)

Sponsored by JSPS KAKENHI Grant-in-Aid for Transformative Research Areas "Latent Chemical Space"
Organizer: Takashi Niwa (Grad. Sch. Pharm Sci., Kyushu Univ.), Takao Nomura (Grad. Sch. Pharm Sci., Hokkaido Univ.)

Rational design and acquisition of bioactive molecules can bring innovation in elucidating new biological functions and creating pharmaceutical and agrochemical seeds. In this area of research for the rational design, we focused on evaluating biological activity using existing compounds and the "Latent Chemical Space" constructed by information analysis technology. Utilizing this strategy, we are advancing in searching for and creating bioactive molecules. While the diversity of bioactivity evaluation and informatics methods will be important, organic synthesis technologies that embody newly designed molecules are also essential. Therefore, this project brought together researchers with these technologies and conducted several collaborative studies. In 2024, a diverse group of public-recruited members with technologies that will contribute to the advancement of the Latent Chemical Space will join this project, further expanding the scope of research collaborations. In this sponsored symposium, researchers participating in this research area will introduce the results of related research and their original technologies for latent space molecular design and discuss the promotion and future development of research based on these results.