The 145th Annual Meeting of the Pharmaceutical Society of Japan (Fukuoka)

Organizer: Koh Takeuchi (Grad. Sch. Pharm. Sci., The Univ. of Tokyo), Umeharu Ohto (Grad. Sch. Pharm. Sci., The Univ. of Tokyo)

Structural biology, which aims to understand biological phenomena based on the three-dimensional structure of biological macromolecules, has made substantial progress through advances in X-ray crystallography, nuclear magnetic resonance, and cryo-electron microscopy, as well as the integration of these techniques with computational techniques. The technical barrier in applying structural analysis to biological macromolecules has been reduced, and structural information has been utilized in broad areas of life science. In addition, the relationship between protein dynamics and function has also been established. There is an increasing demand for high-order structural information in various aspects of drug discovery. The structural analysis of macromolecules potentially leads to the discovery and development of drugs with novel mechanisms of action. This symposium aims to create an opportunity for five leading researchers in the structural biology field to share state-of-the-art techniques with the audience, thereby further promoting the development of structural biology and structure-guided drug discovery.