The 145th Annual Meeting of the Pharmaceutical Society of Japan (Fukuoka)
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Session Details

Oral Presentation(A) Pharmaceutical Chemistry

[27-14-am]Chemical Biology 2

Thu. Mar 27, 2025 8:30 AM - 10:11 AM JST
Thu. Mar 27, 2025 11:30 PM - 1:11 AM UTC
Room 14 (Fukuoka International Congress Center: 405+406 [4F])
Chair: Yuki Mochida, Jumpei Morimoto
8:30 AM - 8:42 AM JST(11:30 PM - 11:42 PM UTC)

[27-14-am01]Development of hepatocyte selective DDS ligand using helical peptides as scaffolds

○Takahito Ito1,2, Nobumichi Ohoka1, Michihiko Aoyama1, Takashi Misawa1, Takao Inoue1, Akiko Ishii-Watabe1, Yosuke Demizu1,2,3 (1. NIHS, 2. Grad. Sch. Med. Life. Sci., Yokohama City Univ., 3. Grad. Sch. Med. Dent. Pharm., Okayama Univ.)
8:42 AM - 8:54 AM JST(11:42 PM - 11:54 PM UTC)

[27-14-am02S]Evaluation of endosomal pH-responsive Aib-containing cell penetrating peptide for the delivery of siRNA

○Keita Wakamori1, Yutaka Enomoto1, Yuzuki Hashikawa1, shun-ichi Wada1, Hidehito Urata1 (1. Osaka Med. Pharm. Univ.)
8:54 AM - 9:06 AM JST(11:54 PM - 12:06 AM UTC)

[27-14-am03S]Development of reversibly photoswitchable stapled peptides based on the arylazopyrazole photoswitch

○Honoka Ogawa1, Kazuya Matsuo1, Tomonori Waku1, Akio Kobori1 (1. Kyoto Institute of Technology)
9:06 AM - 9:18 AM JST(12:06 AM - 12:18 AM UTC)

[27-14-am04]Methods to reduce cytotoxicity of oligoarginine conjugated p53/MDM2 inhibitor peptides

○Kazuma Arakawa1, Yasumichi Inoue1, Yosuke Hisamatsu1, Naoki Umezawa1 (1. Grad. Sch. Pharm. Sci., Nagoya city University)
9:18 AM - 9:23 AM JST(12:18 AM - 12:23 AM UTC)

Break

9:23 AM - 9:35 AM JST(12:23 AM - 12:35 AM UTC)

[27-14-am05S]Light-independent oxygenation of aggregated Aβ using chemiluminescence reaction

○Hiroki Umeda1, Kayo Suda2, Daisuke Yokogawa2, Yuto Azumaya1, Nobuo Kitada3, Shojiro A Maki3, Shigehiro A Kawashima1, Harunobu Mitsunuma1, Yuki Yamanashi1, Motomu Kanai1 (1. Grad. Sch. Pharm. Sci., UTokyo., 2. Grad. Sch. Arts Sci., UTokyo, 3. Grad. Sch. Inf. Eng., Univ. Electro-Comm.)
9:35 AM - 9:47 AM JST(12:35 AM - 12:47 AM UTC)

[27-14-am06S]Amyloid-reoriented enzyme catalysis: substrate protection effect of amyloid against peptide bond cleavage reaction by trypsin

○Manami Hoshi1, Taka Sawazaki1, Yohei Sohma1 (1. Sch. of Pharm. Sci., Wakayama Med. Univ.)
9:47 AM - 9:59 AM JST(12:47 AM - 12:59 AM UTC)

[27-14-am07S]Regio-selective enzyme catalysis using amyloids

○Fuma Murai1, Kai Yamamoto1, Daisuke Sasaki1, Taka Sawazaki1, Youhei Sohma1 (1. Shu. of Pharm. Sci., Wakayama Med. Univ.)
9:59 AM - 10:11 AM JST(12:59 AM - 1:11 AM UTC)

[27-14-am08]Design, Synthesis, and Biological Evaluation of Phosphorylation-inducing Chimeric Small Molecules Targeting Lysine-Specific Demethylase 1

○Chenliang Hu1, Yuri Takada1, Katsunori Endo1, Yasunobu Yamashita1, Yukihiro Itoh1, Takayoshi Suzuki1 (1. Sanken, Osaka Univ.)
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