Session Details
[S26]Research and development on viral vectors and non-viral vectors to realize gene-vector-mediated disease therapy
Thu. Mar 27, 2025 5:00 PM - 6:30 PM JST
Thu. Mar 27, 2025 8:00 AM - 9:30 AM UTC
Thu. Mar 27, 2025 8:00 AM - 9:30 AM UTC
Room 20 (FUKUOKA SUNPALACE: Palace RoomB [2F])
Organizer: Yuma Yamada (Fac. Pharm. Sci., Hokkaido Univ.), Sakurai Fuminori (Grad. Sch. Pharm. Sci., Osaka Univ.)
Technology that enables genome regulation by introducing specific genes into target tissues and cells could contribute to the elucidation of various life phenomena, innovative disease treatments and the development of innovative industries. Gene vectors are essential for establishing this technology. This symposium will cover topics in research and development on viral vectors and non-viral vectors such as Lipid Nano Particles and Liposomes as representative gene vectors. Examples of genome regulation implementation will be discussed, including gene replacement therapy via gene transfer, genetic recombination methods and gene genome editing. There will also be a discussion on the regulation related to the development of medicines needed to realize gene-vector-based disease therapies. This symposium will bring together up-and-coming researchers from different research fields specializing in pharmaceutics, virology, molecular biology and regulation for active discussions related to these topics. It is hoped that this symposium will support to realize gene-vector-mediated disease therapy.
趣旨説明:山田 勇磨(北大院薬)
[S26-1]Delivery of CRISPR/Cas based on lipid nanoparticles
○Yusuke Sato1 (1. Fac. of Pharm. Sci., Hokkaido Univ.)
[S26-2]Roles of extracellular vesicles in antitumor effects of oncolytic viruses
○Fuminori Sakurai1,2 (1. Faculty of Pharm., Kindai Univ., 2. Grad.Sch.Pharm.Sci., Osaka Univ.)
[S26-3]Hypertonic intranasal adenovirus vector vaccines gain nasal epithelia access to exert strong immunogenicity
○Toshiro Hirai1,2,3,4, Yasuo Yoshioka1,2,3,4,5 (1. OTRI, Osaka Univ., 2. RIMD, Osaka Univ., 3. Grad. Sch. Pharm. Sci., Osaka Univ., 4. CAMaD, Osaka Univ., 5. BIKEN)
[S26-4]Cytoplasmic genome regulation; development of organellar genome editing and their application
○Shin-ichi Arimura1 (1. Grad Sch Agr Life Sci, Univ Tokyo)
[S26-5]Development trends and research to ensure the safety of genome editing therapy
○Takao Inoue1 (1. NIHS)