Session Details
[27P-am]Biomolecules
Thu. Mar 27, 2025 8:30 AM - 12:00 PM JST
Thu. Mar 27, 2025 11:30 PM - 3:00 AM UTC
Thu. Mar 27, 2025 11:30 PM - 3:00 AM UTC
Poster (MARINE MESSE FUKUOKA Hall B: Exhibition Room [1F])
[27P-am323]Discovery and biochemical characterization of mammalian D-aspartyl endopeptidase
○GENTA ITO1, Naoko Utsunomiya-Tate1 (1. Faculty Pharm. Sci., Teikyo Univ.)
[27P-am324]Investigation of the signalling pathways involved in the induction of migration inhibition in lung adenocarcinoma cells by human serum albumin-fused human lactoferrin.
○Masahiro Kimura1,2, Hana Nopia2, Yuna Furuya1, Azumi Nishijima1, Sato Atsushi1,2 (1. School of Bioscience and Biotechnology, Tokyo University of Technology , 2. Graduate School of Bionics, Computer and Media Sciences, Tokyo University of Technology)
[27P-am325S]Effects of length and kind of amino acid residue RGD sequences peripheral on platelet aggregation inhibition.
○Ayaka Nezu1, Takuma Nishimura1, Minoru Sugihara2, Etsuko Oyama1, Kenji Hattori1 (1. MEIJI PHARMACEUTICAL UNIVERSITY DEPARTMENT OF ENVIRONMENTAL TOXICOLOGY, 2. MEIJI PHARMACEUTICAL UNIVERSITY)
[27P-am326S]Screening analyses of sugars and sugar chains interacting with S proteins of SARS-CoV-2
○Haruna Yoshida1, Dai Hatakeyama1, Yusuke Miki1, Masaki Shoji1, Rina Hashimoto2, Kazuo Takayama2, Takashi Kuzuhara1 (1. Fac. Pharmaceut. Sci., Tokushima Bunri Univ., 2. CiRA, Kyoto Univ.)
[27P-am327S]Aminoglycoside antibiotics that interacts with the S protein of SARS-CoV-2
○Rei Yamanishi1, Dai Hatakeyama1, Shoji Ueki2, Kentaro Yamaguchi2, Takashi Kuzuhara1 (1. Fac. Pharmaceut. Sci., Tokushima Bunri Univ., 2. Fac. Pharmaceut. Sci. Kagawa Campus, Tokushima Bunri Univ.)
[27P-am328S]Thyroid Hormone and the Intracellular Signaling: Insights from Inhibitor Screening in GH3 Cells
○Shouta Serizawa1, Chihiro Mori2, Naoya Aoki2, Koichi J. Homma2 (1. Grad. Sch. Pharm. Sci., Teikyo Univ., 2. Fac. Pharm. Sci., Teikyo Univ.)
[27P-am329]Intracellular PLIN2 protein level is regulated in a NEK2A dependent transcriptional manner
○Tomohiko Makiyama1, Takashi Obama1, Tomoko Mikajiri1, Hiroyuki Itabe1 (1. Grad. Sch. Pharm., Showa Univ.)
[27P-am330]Purifications including heat or acid denaturing steps of intrinsically disordered proteins in Saccharomyces cerevisiae
○Yeojin Lee1, Suzuna Kuwahara1, Shinya Takazaki1 (1. Fac. of Pharm. Sci., Nagasaki Itn. Univ.)
[27P-am331]Functional analysis of sterol C-3 Ketoreductase Erg27p from fungi Ⅵ
○Masaki Nagase1, Chiaki Okada1, Teruki Yoshimura1 (1. Grad. Sch. Pharm. Sci., Health Sciences University of Hokkaido)
[27P-am332]Analysis of glycan structure and phenotype of Drosophila chondroitin sulfate synthase mutants
○Tomomi Izumikawa1, Kako Yamamoto1, Raiki Sano1, Akiko Toyoda1, Hiroshi Nakato2, Hidenao Toyoda1 (1. Fac. Pharm. Sci. Ritsumeikan Univ., 2. Dept. of Genetics, Cell Biol. and Dev., Univ. of Minnesota)
[27P-am333S]Structural polymorphism and cytotoxicity of Transthyretin amyloid fibrils
○Natsumi Kuwada1, Yuki Inada2, Takuma Yamashita2, Yoshihiro Kobashigawa2, Hiroshi Morioka2, Takashi Sato2 (1. Sch. Pharm., Kumamoto Univ., 2. Grad. Sch. Pharm., Kumamoto Univ.)
[27P-am334S]Evaluation of in vivo antitumor activity of bispecific T cell engager based on cyclic single-chain antibodies
○Takako Nagata1, Tatsuro Aramaki1, Koshiro Doi1, Yoshiki Funakoshi1, Masaya Kato2, Prin Sungwan3, Sena Kamesawa2, Takashi Sato2, Yoshihiro Kobashigawa2, Seiji Okada3, Hiroshi Morioka2 (1. Sch.Pharm., Kumamoto Univ., 2. Grad.Sch.Pharm., Kumamoto Univ., 3. Joint Res.Cent.Human Retrovirus Infection, Kumamoto Univ.)
[27P-am335]Regulation of the expression of heme oxygenase-1 (HO-1) in BAG-1 knockout H1299 cells
○koki takeda1, Hayato Irokawa1, Shusuke Kuge1 (1. Tohoku medical and pharmaceutical univ.)
[27P-am336]Fluoroquinolones inhibit TGF-β-induced Lysyl Oxidase production via JNK/AP-1 pathway in tendon cells.
○Shuen-Chiu Wu1 (1. National Sun Yat-sen University)
[27P-am337]Sturdy of platform technology for predicting antibody aggregation.
○Kazune Ohashi1, Eri Katsumata1, Kota Tanaka1, Hideki Matsuzaki1, Katsuki Naito1, Atsushi Matsuda1 (1. SYSMEX)
[27P-am338S]Abnormal RIG-I splicing in prion disease
○Minori Yoshimura1, Kazunori Sano1, Akari Umezaki1, Tasuku Tanaka1, Soichiro Ushio1, Keiichi Irie1, Kenichi Mishima1 (1. Fac. Pharm. Sci., Fukuoka Univ.)
[27P-am339]Hair damage caused by residual chlorine in tap water
○Ai Fukumura1, Takeyuki Yamamoto1, Hirohito Nakajima1 (1. LIXIL)
[27P-am340]Involvement of the MAPK pathway in the regulation of lipid metabolizing enzyme DDHD1 function
○Naoki Matsumoto1, Yuto Sugiyama1, Kokoro Tominaga1, Kaho Kikuchi1, Kota Miyake1, Kyohei Hara1, Katsuyuki Satake1, Yoko Nemoto-Sasaki1, Atsushi Yamashita1 (1. Dept. of Biol. Chem., Fac. of Pharm. Sci., Teikyo Univ.)
[27P-am341]Study on the instant gelation ability of hyaluronic acid derivatives modified with maleimide and thiol groups and their applications
○Shunichi Fujikawa1 (1. Kewpie Corporation)
[27P-am342]Effect of novel farnesoid X receptor antagonist FLG249 on high-fat diet-induced obese mice
○Yusuke Iguchi1, Yukiko Yamashita1, Keigo Gohda2, Keisuke Oda1, Ko Fujimori3, Yukihiro Sera1, Tsuneo Imanaka1, Masafumi Yamaguchi1,4, Mizuho Une1,4, Naoki Teno4,5 (1. Fac. Pharm. Sci., Hiroshima Int. Univ., 2. CAMM-Kansai, 3. Fac. Pharm., Osaka Med. Pharm. Univ., 4. Grad. Sch. Pharm. Sci., Hiroshima Int. Univ., 5. Fac. Clin. Nut., Hiroshima Int. Univ.)
[27P-am343]Preparation of galectin-2 mutants with reduced ability to form cross-linked products with mucin
○Mayumi Tamura1, Ami Kobori1, Chiharu Ichikawa1, Miyuki Yanagida1, Yuki Ogata1, Tomoharu Takeuchi2, Saori Oka1, Yoichiro Arata1 (1. Fac. Pharm. Sci., Teikyo Univ., 2. Sch. Pharm., Aichi Gakuin Univ.)
[27P-am344]Age-Related Changes in Lipid Composition of Mouse Lungs
○Miina Ozeki1, Taro Sakamoto1, Seizo Sato1 (1. Nissui Corporation)
[27P-am345S]Identification of oxidized phospholipids that activate TRP channels
○Mai Kitahara1, Akito Kuroki1, Eisho Kozakura2, Mirinthorn Jutanom2, Kazushi Morimoto2, Ken-Ichi Yamada2 (1. Sch. Pharm. Sci., Kyushu Univ., 2. Grad. Sch. Pharm. Sci., Kyushu Univ.)
[27P-am346S]Examination of in vitro synthesis of matriglycan using recombinant LARGE
○Nanami Josho1, Shuji Mizumoto1, Emi Imai1, Shuhei Yamada1 (1. Fac. Pharm., Meijo Univ.)
[27P-am347S]A biosynthetic enzyme of heparan sulfate, EXTL3, is required for T cell differentiation in vivo
○Nanako Soga1, Shuji Mizumoto1, Yukina Ohara1, Tadashi Yamashita2, Akira Sugawara3, Shuhei Yamada1 (1. Fac. Pharm., Meijo Univ., 2. Fac. Vet., Azabu Univ., 3. Grad. Sch. Med., Tohoku Univ.)
[27P-am348S]Inactive Atp9 shows dominant-negative behavior, causing depletion of cellular ATP
○Kenta Terai1,2, Takeshi Ito3, Yasuo Shinohara1,2 (1. Inst. Adv. Med. Sci., Tokushima Univ., 2. Grad. Sch. Pharm. Sci., Tokushima Univ., 3. Grad. Sch. Agr., Ehime Univ.)
[27P-am349]ROS derived from methylmalonic acid promotes colorectal cancer cell proliferation
○Arowu R Tanaka1, Chifuyu Monde1, Mizuki Arii1, Chiho Murakami1 (1. Facult. Pharm., Yasuda Women’s University)
[27P-am350S]Behavioral analyses in mice with complete loss of EXTL3, specifically in excitatory glutamatergic neurons
○Yuma Kanoh1, Shuji Mizumoto1, Daisuke Ibi2, Masayuki Hiramatsu2, Akira Sugawara3, Shuhei Yamada1 (1. Dept. Pathobiochem., Fac. Pharm., Meijo Univ., 2. Dept. Chem. Pharmacol., Fac. Pharm., Meijo Univ., 3. Grad. Sch. Med., Tohoku Univ.)
[27P-am351]Changes in Components and Functional Improvement of Pimpinella L. by UV Irradiation
○Hayato Ohga1, Kyouko Shimojima2, Mikiyo Wada3, Hiroshi Oshiumi1, Gaku Sato1 (1. Saishunkan Pharmaceutical Co.,Ltd., 2. Katakura and Co-op Agri Corp., 3. Kumamoto University)
[27P-am352S]Therapeutic effect of liver-specific overexpression of LPLAT13 in high-fat diet fed-mice
○Yurie Shimizu1, Kahori Shimizu2, Ayano Otomo1, Miho Iwasaki1, Fuminori Sakurai2,3, Hiroyuki Mizuguchi2,4,5,6,7, Koji Tomita1, Toru Nisinaka1 (1. Pharma., Osaka Ohtani Univ, 2. Grad. Sch. of Pharma. Sci., Osaka Univ, 3. Dept. Pharma., Kindai Univ, 4. Natl. Inst. Biomed. Innov. Health Nutr, 5. MEIC, Osaka Univ., 6. OTRI, Osaka Univ, 7. CiDER, Osaka Univ)
[27P-am353][Withdrawn]
[27P-am354S]Glycoproteomic uncovering of O-glucose glycan modifications on skeletal muscle cell-derived NOTCH1/2
○Kana Fukazawa1, Yuuki Kurebayashi1, Koki Kato1, Fuga Suzuki1, Yohei Tsukamoto2, Akira Minami1,3, Tadanobu Takahashi1, Tetsuya Okajima2,4, Hideyuki Takeuchi1 (1. Sch. Pharm. Sci., Univ. of Shizuoka, 2. Grad. Sch. Med., Nagoya Univ., 3. Fac. Phram., Juntendo Univ., 4. iGCORE, Nagoya Univ.)
[27P-am355]Comparison of anti-inflammatory effects of lysophospholipids in HT-29, a human colon cancer-derived epithelial cell
○Yuya Ohtsuki1, Erena Nakamura1, Moe Asakami1, Rena Morikawa1, Akira Tokumura1 (1. Fac. Pharm., Yasuda Women's Univ.)
[27P-am356]Purification of adenosine deaminase isozymes from human breast milk
○Mayu Kashiwaya1, Moeko Ito1, Mayuko Soma1,2, Ainari Konda1,2, Junichi Kashiwakura1, Sachiko Iwaki-Egawa1 (1. Hokkaido University of Science, 2. Tenshi Hospital)
[27P-am357S]Comparison of amino acid compositions in bivalves: Concentration of D-alanine in the siphon of the geoduck clam Panopea japonica and evaluation of associated enzyme activities
○Tomoya Takaura1, Mayu Onozato1, Wataru Shinohara2, Takehiro Tsukada3, Tatsuya Sakamoto1, Kenji Okoshi3,4, Takeshi Fukushima1 (1. Faculty of Pharmaceutical Sciences, Toho University, 2. Chiba Municipal Chiba High School, 3. Faculty of Science, Toho University, 4. Toyo Institute of Food Technology)
[27P-am358S]Relevance between myotube differentiation and selenoprotein expression in myoblast cell line C2C12
○Kouta Shiigai1, Saori Yoshioka1, Hirofumi Oino 1 (1. Fac. Pharm. Sci., Nihon Pham. Univ.)
[27P-am359]A simple activity assay for acid ceramidase using a novel fluorescent substrate LAMCA
○Kazuhito Tsuboi1, Misaki Saito1, Taichi Aoki1, Sakura Itsukuma1, Keita Mizuta1,2, Keisuke Kitakaze1, Yasuhiro Takenouchi1, Hironobu Ishimaru1, Yasuo Okamoto1 (1. Kawasaki Med. Sch., 2. Nara Med. Univ.)
[27P-am360]Expression analysis of O-mannosyl glycan of α-dystroglycan in single cell clones isolated from MIA PaCa-2 pancreatic cancer cells.
○Rieko Imae1, Toshiyuki Ishiwata2, Hiroshi Manya1 (1. Mol. Glyco., Tokyo Metro. Inst. of Gerontol., 2. Div. of Aging and Carcinogenesis, Tokyo Metro. Inst. of Gerontol.)
[27P-am361S]Functional evaluation of various paramylons using insoluble β-glucans binding assay of Dectin-1 lectin–like receptor
○Hanako Chiba1, Noriyoshi Manabe1, Junko Naito2, Norihisa Nishida2, Naohito Ohno3, Yoshiki Yamaguchi1 (1. Tohoku Med. Pharm. Univ., 2. Kobelco Eco-Solutions Co., Ltd, 3. Tokyo Univ. Pharm. Life Sci.)
[27P-am362]Exploring the Power of Structural Biology on Degrader Discovery
○Yifan Hu1, Wang Cheng1, Hui Shi1, Feng Wang1, Larry Jin1, Jiaquan Wu1 (1. Biortus Biosciences Co. Ltd., 6 Dongsheng West Road, 214437, Jiangyin, Jiangsu, China.)
[27P-am363]Rapid authentication of the medicinal crop Cirsium setosum and discrimination from its adulterants via polymerase chain reaction integrated with a lateral flow assay (PCR-LFA)
○MENG-SHIOU LEE1, Jia-An Ling1, Kun-Chang Wu2, Ming-Kuem Lin1 (1. Department of Chinese Pharmaceutical Science and Chinese Medicine Resources, China Medical University, Taiwan, 2. School of Pharmacy, China Medical University, Taiwan)
[27P-am364S]Development of a method for efficient purification of in-cell interacting proteins using a labelable, cleavable and photo-cross-linkable amino acid
○Tomoya Tsubota1, Masahiro Takayama1,2, Kosuke Chiba1, Takumi Yoshida1, Takao Yamaguchi1, Yu-Shi Tian1, Daisuke Takaya1, Kaori Fukuzawa1, Satoshi Obika1,3,4, Shinsaku Nakagawa1, Nobumasa Hino1,4 (1. Grad. Sch. Pharm. Sci. Osaka Univ., 2. SHIONOGI, 3. OTRI, Osaka Univ., 4. CiDER, Osaka Univ.)
[27P-am365S]Development of covalent ACE2-Fc proteins that efficiently neutralize SARS-CoV-2 variants
○Kyosuke Suzuki1, Risa Takada1, Nagisa Tokunoh2,3, Chikako Ono2,4, Haruna Ogami1, Takafumi Nishiura1, Yoshiharu Matsuura2,4, Yasuo Yoshioka1,2,3,4, Shinsaku Nakagawa1, Nobumasa Hino1,4 (1. Grad. Sch. Pharm. Sci., Osaka Univ., 2. RIMD, Osaka Univ., 3. Res. Found. for Microbial. Dis., Osaka Univ., 4. CiDER, Osaka Univ.)
[27P-am366]Proteomic analysis of the MASH model monkey liver tissue affected by 4-hydroxynonenal
○Yurie Mori1, Tetsumori Yamashima2, Hatasu Kobayashi1, Yuri Miura3, Mariko Murata1, Shinji Oikawa1 (1. Mie University Graduate School of Medicine, 2. Kanazawa University Graduate School of Medical Science, 3. Tokyo Metropolitan Institute of Gerontology)
[27P-am367]Effects of Maternal Postbiotic Supplementation During Pregnancy on Fear and Stress Responses in Mouse Offspring
○JAEBIN LEE1, Kensuke Nakajima2, Masashi Fukasawa1, Shogo Shimabukuro1, Kazuma Takahashi1, Kyoko Fujimoto1 (1. Div.Biochemistry, Nagasaki International Univ., 2. Div.Pharmaceutical Health Care and Sciences, Nagasaki International Univ.)
[27P-am368S]The cholesterol transporter NPC1L1 binds β-sitosterol using extracellular domain but doesn’t facilitate its insertion into the cell membrane.
○Kento Handa1, Akiho Shima1, Jun Kamishikiryo1 (1. Dept. Biochem. Fac. Pharm. Pharmaceut. Sci., Fukuyama Univ.)
[27P-am369S]The Analysis of the Mechanisms Regulating Beige Adipocyte Differentiation by IRBIT
○Iori Yamamoto1, Koichi Hamada1, Yurika Ito1, Hiromi Takamura1, Nanami Sugaya1, Asuka Kobayashi1, Yasuaki Goto1, Katsuhiko Mikoshiba2, Akihiro Mizutani1 (1. Showa Pharm. Univ., 2. ShanghaiTech Univ.)