The 145th Annual Meeting of the Pharmaceutical Society of Japan (Fukuoka)

Organizer: Asako Yamayoshi (Dept. Life Sci. Tech., Science Tokyo), Yu Ishima (Kyoto Pharm. Univ.)

Supramolecules are multiple molecules assembled in an orderly manner by bonds other than covalent bonds. Examples of supramolecules include biological components such as DNA and lipid bilayers, as well as antibody-antigen complexes, and albumin-drug complexes. Recently, antibody-drug complexes, and albumin-drug complexes have been developed one after another as supramolecular drugs, and it is expected that supramolecular drugs will become more diverse and sophisticated in the future. On the other hand, there exists a surprising form of symbiosis in the body, where self and non-self are recognized, yet symbiosis is established through "appropriate communication" between the two. In other words, elucidating and understanding the actual state of this "appropriate communication" between self and non-self will be extremely important in the development of safe and efficient supramolecular drugs. In this symposium, we will have lectures on elucidating the actual state of "weak interactions'' between drugs including biomolecules and supramolecules, what material symbiosis is, and the latest research on supramolecular drugs in the future, and we will discuss the next generation of new pharmacology.