Session Details
[S32]Pharmacological approaches to therapeutic target discovery and drug resistance in cancer
Fri. Mar 28, 2025 3:00 PM - 4:30 PM JST
Fri. Mar 28, 2025 6:00 AM - 7:30 AM UTC
Fri. Mar 28, 2025 6:00 AM - 7:30 AM UTC
Room 6 (Fukuoka International Congress Center: 203 [2F])
Organizer: Kazuhiro Katayama (Sch. Pharm., Nihon Univ.), Inoue Yasumichi (Grad. Sch. Pharm. Sci., Nagoya City Univ.)
Cancer is the leading cause of death in Japan. The age-adjusted mortality rate for cancer has been declining for 20 years, and the crude rate has begun to level off. This trend is due to advances in cancer treatment, particularly surgery, radiotherapy and chemotherapy. New treatments, such as molecular targeted therapy and immunotherapy, have transformed cancer care. Many new drugs have been developed over the past two decades, and immune checkpoint inhibitors have been a game changer. These new drugs and combination therapies are becoming standard of care in cancer treatment, and the role of pharmaceutical research and pharmacists has grown significantly.
This symposium will focus on pharmaceutical approaches to cancer research, covering topics such as understanding cancer cell characteristics, exploring therapeutic targets, developing new drugs, and analyzing drug resistance, with discussions based on our recent studies. We aim to inspire young researchers and contribute to the revitalization of cancer research by providing insight into these developments. Advances in cancer research require the integration of knowledge and expertise from diverse fields such as biology, biochemistry, pharmaceutical hygiene, pharmacology and pharmacokinetics. It is truly an "all pharmacy" endeavor that requires a comprehensive blend of knowledge, skills and experience.
This symposium will focus on pharmaceutical approaches to cancer research, covering topics such as understanding cancer cell characteristics, exploring therapeutic targets, developing new drugs, and analyzing drug resistance, with discussions based on our recent studies. We aim to inspire young researchers and contribute to the revitalization of cancer research by providing insight into these developments. Advances in cancer research require the integration of knowledge and expertise from diverse fields such as biology, biochemistry, pharmaceutical hygiene, pharmacology and pharmacokinetics. It is truly an "all pharmacy" endeavor that requires a comprehensive blend of knowledge, skills and experience.
オーガナイザー挨拶:片山 和浩(日本大薬)
[S32-1]Drug development for Japanese patients using real world data from gene panel testing conducted under national health insurance system
○Takashi Kohno1 (1. Natl Cancer Ctr C-CAT)
[S32-2]Tumor progression by TGF-β signaling inhibitor, TMEPAI: development of novel anti-cancer drugs
○Susumu Itoh1, Naoko Nakano1, Kenya Furudate1, Etsu Tashiro1 (1. Lab. of Biochem. Showa Pharma. Univ.)
[S32-3]Development of targeted protein degraders for cancer therapy
○Nobumichi Ohoka1 (1. NIHS)
[S32-4]Sotorasib function as a pan RAS G12C inhibitor
○Noritaka Tanaka1 (1. Aichi Cancer Center)
[S32-5]Molecular mechanism of stress adaptation inducing proteasome inhibitor non-responsiveness and therapeutic drug development
○Yasumichi Inoue1 (1. Grad. Sch. Pharm. Sci., Nagoya City Univ.)
[S32-6]Molecular mechanisms of resistance to FLT3 inhibitors and development of drugs to overcome the resistance
○Kazuhiro Katayama1 (1. Sch. Pharm., Nihon Univ.)