Session Details
[S37]Pioneering cancer research through interdisciplinary collaboration
Fri. Mar 28, 2025 4:45 PM - 6:15 PM JST
Fri. Mar 28, 2025 7:45 AM - 9:15 AM UTC
Fri. Mar 28, 2025 7:45 AM - 9:15 AM UTC
Room 6 (Fukuoka International Congress Center: 203 [2F])
Organizer: Shinya Ohata (Facul. Pharm., Musashino Univ.), Sachiko Toma (NAIST)
In Japan, cancer represents the primary cause of mortality, accounting for over a quarter of all deaths. Despite the advent of numerous therapeutic agents and pharmaceuticals, these have yet to be validated for the treatment of rare and refractory cancers, leaving significant unmet medical needs. As evidenced by the pivotal role played by structural biology in the development of imatinib, it is anticipated that collaboration among experts in disparate fields will yield novel ideas and approaches that will culminate in transformative outcomes. The symposium will present the works of leading researchers in the field of cancer research. This will include the development of in vivo model systems, the discovery of new drug targets, and the development of drugs using an integrated approach that combines biological methods with structural biology, synthetic organic chemistry, radiochemistry, computer science, developmental engineering, and other techniques. The research of these frontrunners will be introduced, and the importance of interdisciplinary collaboration in the development of diagnostic and therapeutic methods for cancer and other diseases will be discussed.
趣旨説明:大畑 慎也(武蔵野大薬)
[S37-1]Unraveling the molecular mechanisms of supratentorial ependymoma tumorigenesis through animal modeling
○Daisuke Kawauchi1, Zhize Xiao1,2, Naofumi Uesaka2 (1. Dept of Neuro-Oncol, Institute of Brain Sci Grad Sch of Med Sci, Nagoya City Univ., 2. Dept of Cognitive Neurobiol, Grad Sch of Med & Den Sci, Institute of Sci. Tokyo)
[S37-2]Non-classical nuclear transport mechanisms of cancer-related proteins approached from structural biology and the search for drug targets
○Sachiko Toma-Fukai1 (1. NAIST)
[S37-3]Understanding mechanisms of resistance to molecular-targeted drugs by analyzing cancer patient derived specimens and molecular dynamics simulations
○Ryohei Katayama1,2, Mitsugu Araki3 (1. Cancer Chemother Ctr, JFCR, 2. Grad Sch Fronti Sci, Univ of Tokyo, 3. Grad Sch Med, Kyoto Univ)
[S37-4]Development of new cancer therapies by integrating physical pharmaceutical science and computational chemistry
○Mikako Ogawa1 (1. Dept Pharm, Hokkaido Univ)