Session Details
[S42]Current status and issues of drug-induced liver injury
Sat. Mar 29, 2025 10:15 AM - 11:45 AM JST
Sat. Mar 29, 2025 1:15 AM - 2:45 AM UTC
Sat. Mar 29, 2025 1:15 AM - 2:45 AM UTC
Room 16 (MARINE MESSE FUKUOKA Hall B: Conference Room1-2 [2F])
Organizer: Atsushi Kawase (Fac. Pharm., Kindai Univ.)
Drug-induced liver injury (DILI) is classified into toxic and idiosyncratic types based on the mechanisms of onset. Toxic liver injury is dose-dependent, while idiosyncratic liver injury involves genetic factors and variations in immune response, making it difficult to predict. DILI is also seen not only with antibiotics and antipyretics/analgesics, but also with herbal medicines, health foods, supplements, etc., and there are also increasing reports of cases with immune checkpoint inhibitors. We planned this symposium to provide a forum for widely sharing the latest knowledge and issues regarding DILI.
Dr. Kawase from Kindai University, Dr. Kato from Osaka Med. Pharm. Univ., Dr. Aoki from Grad. Sch. Pharm. Sci., Chiba Univ., and Dr. Fukami from Faculty of Pharmaceutical Sciences, Kanazawa University, WPI-NanoLSI, Kanazawa University will present their research results on DILI.
It promises to be a highly informative event with valuable insights for all participants.
Dr. Kawase from Kindai University, Dr. Kato from Osaka Med. Pharm. Univ., Dr. Aoki from Grad. Sch. Pharm. Sci., Chiba Univ., and Dr. Fukami from Faculty of Pharmaceutical Sciences, Kanazawa University, WPI-NanoLSI, Kanazawa University will present their research results on DILI.
It promises to be a highly informative event with valuable insights for all participants.
趣旨説明：川瀬 篤史（近畿大薬）
[S42-1]Association between risk of drug-induced liver injury and reactive metabolites, acyl glucuronides
○Atsushi Kawase1, Hiroaki Shimada1, Fuminori Sakurai1 (1. Fac. Pharm., Kindai Univ.)
[S42-2]Inflammasome activation and idiosyncratic drug-induced liver injury
-Fusion study of basic and real-world data-
○Ryuji Kato1 (1. Osaka Med. Pharm. Univ.)
[S42-3]Recent insights into HLA-dependent idiosyncratic liver injury
○Shigeki Aoki1, Akira Kazaoka1,2, Kousei Ito1 (1. Grad. Sch. Pharm. Sci., Chiba Univ., 2. Fac. Pharm., Meijo Univ.)
[S42-4]Elucidation of a novel protective function of AADAC against drug-induced liver injury through ferroptosis suppression
○Tatsuki Fukami1,2 (1. Faculty of Pharmaceutical Sciences, Kanazawa University, 2. WPI Nano Life Science Institute (WPI-NanoLSI), Kanazawa University)