The 146th Annual Meeting of the Pharmaceutical Society of Japan (Osaka)
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Session Details

Oral Presentation(C) Pharmaceutical Biology

[27-22-am]Nervous System 1

Fri. Mar 27, 2026 9:30 AM - 11:18 AM JST
Fri. Mar 27, 2026 12:30 AM - 2:18 AM UTC
Room 22 (2102, Bldg. 2, Area 4 [1F])
Chair: Takuji Machida, Yuri Ikeda-Matsuo
9:30 AM - 9:42 AM JST(12:30 AM - 12:42 AM UTC)

[27-22-am01S]The role of CD11c+ microglial subset in Alzheimer's disease model.

○Kohei Nomaki1, Risako Fujikawa2, Takashi Saito3, Takaomi Saido4, Makoto Tsuda1 (1. Grad. Sch. Pharma. Sci., Kyushu Univ., 2. Fac. Pharma. Sci., Fukuoka Univ., 3. Inst. Brain Sci., Grad. Sch. Med. Sci., Nagoya City Univ., 4. RIKEN Center for Brain Science.)
9:42 AM - 9:54 AM JST(12:42 AM - 12:54 AM UTC)

[27-22-am02S]Microglia-Dependent Inflammatory Responses and the Role of Galectin-3 in an MPTP-Induced Parkinson’s Disease Model

○Ayane Nakano1, Shogo Maekawa2, Koya Zama2, Kazuki Ohuchi1, Hisaka Kurita1, Ryo Honda3, Masatoshi Inden1 (1. Grad. Sch. Pharm. Sci., Gifu Pharm. Univ., 2. Pharm. Sci., Gifu Pharm. Univ., 3. Grad. Sch. Drug Disc. & Med. Info. Sci., Gifu Univ.)
9:54 AM - 10:06 AM JST(12:54 AM - 1:06 AM UTC)

[27-22-am03S]Experimental colitis triggers the blood-brain barrier dysfunction accompanied by pathological alterations in brain pericytes

○Junko Mizoguchi1, Fuyuko Takata1, Takuro Iwao1, Yasuyoshi Tanaka1, Akio Nakashima2,3, Osamu Imakyure2,3, Shinya Dohgu1 (1. Dept. Pharm. Care & Health Sci., Fac. Pharm. Sci., Fukuoka Univ., 2. Dept. Pharm., Fukuoka Univ. Chikushi Hosp., 3. Pharm. & Health Care Mgmt., Fac. Pharm. Sci., Fukuoka Univ.)
10:06 AM - 10:18 AM JST(1:06 AM - 1:18 AM UTC)

[27-22-am04S]The role of brain perivascular macrophages in blood-brain barrier dysfunction caused by decreased cerebral blood flow

○Sayaka Matsumura1, Yoshiyuki Moriyama1,2, Yui Iwatani2, Hideki Hayashi1,2, Norio Takagi1,2 (1. Dept. Appl. Biochem., Grad. Sch. Pharm., Tokyo Univ. Life Sci., 2. Dept. Appl. Biochem., Sch. Pharm., Tokyo Univ. Life Sci.)
10:18 AM - 10:30 AM JST(1:18 AM - 1:30 AM UTC)

[27-22-am05S]Analysis of the mechanism by which the candida virulence factor candidalysinsuppresses P. gingivalis outer membrane lipoprotein-induced IL-1β production in microglia

○Ayaka Kawahara1, Haruka Kanagawa1, Hidetoshi Tozaki-Saitoh2, Saori Nonaka1, Hiroshi Nakanishi1 (1. Fac. Pharm. Yasuda Women’s Univ., 2. Sch. Pharm. at Fukuoka Int. Univ. Health and Welfare)
10:30 AM - 10:42 AM JST(1:30 AM - 1:42 AM UTC)

[27-22-am06S]An alternative NF-κB pathway in microglia activated by outer membrane vesicles from P. gingivalis

○Chiharu Morimoto1, Uzuki Takemori1, Hidetoshi Tozaki-Saitoh2, Saori Nonaka1, Hiroshi Nakanisi1 (1. Fac. Pharm. Yasuda Women's Univ., 2. Sch. Pharm. at Fukuoka Int. Univ. Health and Welfare)
10:42 AM - 10:54 AM JST(1:42 AM - 1:54 AM UTC)

[27-22-am07S]Elucidation of Pathological Molecular Mechanisms in the Temporal Lobe White Matter of Patients with Myotonic Dystrophy Type 1 by High-Depth Quantitative Proteome Analysis

○Shota Okamura1, Yuki Maeda2, Yosuke Hashimoto1,2, Hiroshi Shimizu3, Masayuki Nakamori4, Yasuo Uchida1,2 (1. Sch. Pharm. Sci., Hiroshima Univ., 2. Grad. Sch. Biomed. Health Sci. Hiroshima Univ., 3. Brain Res. Ins. Niigata Univ., 4. Grad. Sch. Med. Yamaguchi Univ.)
10:54 AM - 11:06 AM JST(1:54 AM - 2:06 AM UTC)

[27-22-am08]Cell-to-Cell transmission of TDP-43 proteins with distinct conformations: Implication of endocytic pathway for the uptake of TDP43

○Eiichi Tokuda1, Rina Matsuhashi1, Tomizawa Honoka1, Kano Hisao1, Kosuge Yasuhiro1, Miyasaka Tomohiro1 (1. Nihon Univ.)
11:06 AM - 11:18 AM JST(2:06 AM - 2:18 AM UTC)

[27-22-am09]ER stress-dependent induction of the neurotoxic reactive astrocyte phenotype in cultured astrocytes.

○Akiko Yamamuro1, Tomofumi Okuno1, Fumiya Shibagaki1, Yuki Ishumaru1, Yasuhiro Yoshioka1 (1. Faculty of Pharmaceutical Sciences Setsunan University)
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