The 146th Annual Meeting of the Pharmaceutical Society of Japan (Osaka)
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Session Details

Poster Presentation(D) Pharmaceutical Health Sciences and Environmental Toxicology

[28-61-am]Metabolism and metabolic activation of chemical substances (cancer) 3

Sat. Mar 28, 2026 9:30 AM - 11:30 AM JST
Sat. Mar 28, 2026 12:30 AM - 2:30 AM UTC
Room 61 (4201, Bldg. 4, Area 4 [2F]) (2)
Discusser: Kohei Matsuo, Ami Oguro

[28-61-am-09S]Changes of xenobiotic-metabolizing enzymes by sex, pregnancy, and chemical exposure in mouse olfactory epithelium

○Hiroki Kanda1, Naoki Takaoka1, Shigeru Ohta1, Seigo Sanoh1 (1. Sch. Pharma. Sci., Wakayama Med. Univ.)

[28-61-am-10S]Kinetic study of the methylation of reactive sulfur species by thiopurine S-methyltransferase

○Momoka Uchida1, Yasunori Fukumoto2, Yoshikazu Yamagishi3, Rina Mukasa2, Yu-ki Tanaka2, Yasumitsu Ogra2 (1. Fac. Pharm. Sci., Chiba Univ., 2. Grad. Sch. Pharm. Sci., Chiba Univ., 3. Grad. Sch. Med., Chiba Univ.)

[28-61-am-11S]Investigation of a gold nanoparticle–based trapping approach for reactive metabolites: A case study using the acetaminophen reactive metabolite NAPQI

○Azuna Kitagawa1, Naoki Takaoka1, Noriko Nakamura2, Seiichi Ohta2, Shigeru Ohta1, Seigo Sanoh1 (1. Sch. Pharma. Sci., Wakayama Med. Univ., 2. Grad. Sch. Eng., Univ. of Tokyo)

[28-61-am-12S]Evaluation of CYP oxidation reaction inhibition by food polyphenols

○Nonoka Kurata1, Keita Saito1, Hiroyuki Kataoka1 (1. School of Pharmacy, Shujitsu University)

[28-61-am-13S]Comparison of uptake and cytotoxicity of PFAS with different carbon chain lengths : A study using liver- and kidney- derived cell systems

○Yuka Yamada1, Naoki Takaoka1, Chise Tateno1,2,3, Yaichiro Kotake3, Shigeru Ohta1, Seigo Sanoh1 (1. Sch. Pharma. Sci., Wakayama Med. Univ., 2. PhoenixBio Co.,Ltd., 3. Grad. Sch. Biomed. Health Sci., Hiroshima Univ.)

[28-61-am-14S]Modulation of human CYP3A4 activities by gut microbiota – derived indole and imidazole metabolites

○Ryota Fukuda1, Naoki Takaoka1, Shigeru Ohta1, Seigo Sanoh1 (1. Sch. Pharma. Sci.,Wakayama Med. Univ.)

[28-61-am-15S]Generation of reactive metabolites and glutathione-dependent detoxification mechanisms in mouse olfactory epithelium

○Kotono Kaino1, Naoki Takaoka1, Shigeru Ohta1, Seigo Sanoh1 (1. Sch. Pharma. Sci., Wakayama Med. Univ.)

[28-61-am-16S]Metabolism of odor molecules by cytochrome P450 and UDP-glucuronosyltransferase in the olfactory epithelium and the effects of their inhibition by drugs

○Ayana Nishide1, Naoki Takaoka1, Shinichi Ikushiro2, Shigeru Ohta1, Seigo Sanoh1 (1. Sch. Pharma. Sci., Wakayama Med. Univ., 2. Grad. Sch. Eng., Toyama Prefectural Univ.)
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