[29-22-am] Mass spectrometry analysis 2/Radioactive compounds 3 | The 146th Annual Meeting of the Pharmaceutical Society of Japan (Osaka)

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Oral Presentation(B) Pharmaceutical Physics

[29-22-am]Mass spectrometry analysis 2/Radioactive compounds 3

Sun. Mar 29, 2026 9:30 AM - 11:18 AM JST
Sun. Mar 29, 2026 12:30 AM - 2:18 AM UTC

Room 22 (2102, Bldg. 2, Area 4 [1F])

Chair: Hirofumi Hanaoka, Kenichi Nagase

9:30 AM - 9:42 AM JST(12:30 AM - 12:42 AM UTC)

[29-22-am01S]Development and evaluation of ²²⁵Ac-Macropa complexes targeting α_vβ₃integrin

○Hiroaki Echigo¹, Masayuki Munekane¹, Takeshi Fuchigami¹, Kenji Mishiro¹, Hidetoshi Kikunaga², Kazuaki Tsukada², Takuya Yokokita², Kenji Shirasaki³, Jun Ichinose⁴, Kinuya Seigo⁵, Kazuma Ogawa¹ (1. Grad. Sch. Pharm., Kanazawa Univ., 2. Tohoku Univ., 3. Osaka Univ., 4. QST, 5. Grad. Sch. Med., Kanazawa Univ.)

9:42 AM - 9:54 AM JST(12:42 AM - 12:54 AM UTC)

[29-22-am02S]Contribution of optical isomerism to the pharmacological properties of radiohalogen-labeled tyrosine derivatives with a neopentyl glycol scaffold

○Sohta Tatsuta¹, Kento Kannaka², Koichi Sawada³, Takashi Iimori³, Takashi Uno⁴, Nobuki Kazuta², Hiroyuki Suzuki², Tomoya Uehara² (1. Chiba Univ., 2. Grad. Sch. Pharm. Sci, Chiba Univ., 3. Chiba Univ. hospital, 4. Grad. Sch. Med. Sci, Chiba Univ.)

9:54 AM - 10:06 AM JST(12:54 AM - 1:06 AM UTC)

[29-22-am03S]Development of switching-labeled chelates applicable to the production of ¹¹¹In/²²⁵Ac-labeled antibodies

○Yuki Itagaki¹, Taichi Muto¹, Shiori Horikoshi¹, Kento Kannaka¹, Nobuyuki Kazuta¹, Hiroyuki Suzuki¹, Atsushi Tsuji², Tomoya Uehara¹ (1. Grad. Sch. Pharm. Sci., Chiba Univ., 2. QST)

10:06 AM - 10:18 AM JST(1:06 AM - 1:18 AM UTC)

[29-22-am04S]Synthesis of a stable astatine labeling site

○Saki Hirata¹, Kenji Mishiro¹, Takeshi Fuchigami¹, Masayuki Munekane¹, Masashi Murakami², Kazuhiro Ooe², Atsushi Toyoshima², Kazuma Ogawa¹ (1. Grad. Sch. Med. Sci., Kanazawa Univ., 2. Osaka Univ.)

10:18 AM - 10:30 AM JST(1:18 AM - 1:30 AM UTC)

[29-22-am05S]Comprehensive LC-MS/MS analysis of glycosphingolipids and ceramides in renal cell carcinoma cell lines for elucidating metastatic pathophysiology

○Natsuki Sano¹, Masamitsu Maekawa^1,2,3, Tomonori Sato³, Yoshihide Kawasaki³, Nariyasu Mano^1,2,3 (1. Fac. of Pharm. Sci., Tohoku Univ., 2. Dept. Pharm. Sci., Tohoku Univ. Hosp., 3. Grad. Sch. Med., Tohoku Univ.)

10:30 AM - 10:42 AM JST(1:30 AM - 1:42 AM UTC)

[29-22-am06S]Novel bottom-up proteomics approaches using protease type XIII from Aspergillus saitoi

○Motoya Uno¹, Ryota Tomioka², Kosuke Ogata^1,2, Eisuke Kanao^1,2,3, Yasushi Ishihama^1,2,3 (1. Pharm.Sci., Kyoto Univ., 2. Grad. Sch. Pharm. Sci., Kyoto Univ., 3. NIBIOHN)

10:42 AM - 10:54 AM JST(1:42 AM - 1:54 AM UTC)

[29-22-am07S]Development of a simultaneous analytical method of six metabolites for estimating of three CYP enzymatic activity related to the metabolism of antipsychotic drugs

○HAOZHU WANG¹, Masamitsu Maekawa^1,2, Nariyasu Mano^1,2 (1. Grad. Sch. Pharm. Sci., Tohoku Univ., 2. Dept. Pharm. Sci., Tohoku Univ. Hosp.)

10:54 AM - 11:06 AM JST(1:54 AM - 2:06 AM UTC)

[29-22-am08S]Large-scale profiling of protein structural stability by limited proteolysis

○Roko Nakashima¹, Kosuke Ogata^1,2, Yasushi Ishihama^1,2,3 (1. Pharm.Sci., Kyoto Univ., 2. Grad. Sch. Pharm. Sci., Kyoto Univ., 3. NIBIOHN)

11:06 AM - 11:18 AM JST(2:06 AM - 2:18 AM UTC)

[29-22-am09]Breath biomarker for monitoring lipid peroxidation and ferroptosis

○yuta matsuoka¹ (1. Grad. Sch. Med. Kyoto Univ.)

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