Session Details
[3S07m]Decoding intracellular pathology
Thu. Mar 12, 2026 8:50 AM - 10:40 AM JST
Thu. Mar 12, 2026 11:50 PM - 1:40 AM UTC
Thu. Mar 12, 2026 11:50 PM - 1:40 AM UTC
Room 7(School of Nursing Building, 1F, 102)
Organizers/Chairs: Sho Aki (The University of Osaka), Daisuke Shimura (Waseda University (WIAS))
Recent advances in molecular biology and genetics have highlighted that structural and functional disruptions of organelles—such as mitochondria, lysosomes, the endoplasmic reticulum, and their interactions with the plasma membrane—contribute to a wide range of diseases, including neurodegeneration, cardiovascular dysfunction, metabolic disorders, and immune dysregulation. Increasing attention is also being paid to inter-organelle communication as a key factor in maintaining cellular homeostasis. This symposium aims to promote cross-cutting insights beyond isolated pathologies. It seeks to advance understanding of intracellular processes, encourage new research in this exciting field, and foster the development of future diagnostic and therapeutic strategies.
Introduction
[3S07m-01]GJA1-20k utilizes phosphoinositide binding to organelle localization and contacts
*Daisuke Shimura1 (1. Waseda University (WIAS))
[3S07m-02]Cells adapt to extracellular acidic pH through TM9SF3-mediated PI(4,5)P2 flop
*Keisuke Sako1 (1. Department of Anatomy Keio University School of Medicine)
[3S07m-03]Mitochondrial unfolded stress response in adipose tissue as a novel therapeutic target for endotoxin-induced sepsis
*Yuka Nozaki1, Yuhei Mizunoe1, Masaki Kobayashi2, Yoshikazu Higami1 (1. Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2. Institute for Human Life Science, Ochanomizu University, Tokyo, Japan)
[3S07m-04]Mitochondrial Organelle Contacts in Stress Responses
*Isshin Shiiba1 (1. Gakushuin Univ.)
[3S07m-05]PI(3,4)P2 drives sequential steps in outer mitochondrial membrane fusion
*Sho Aki1 (1. Organelle dynamics modeling, Premium Research Institute for Human Metaverse Medicine (WPI-PRIMe), The University of Osaka)
