Symposia & Panel Discussion（ガチ討論会）
Symposia & Panel Discussion
Main Symposium & Panel Discussion
Co-organized by：Institute for the Advanced Study of Human Biology, Kyoto University (ASHBi)
Day 3 (June 21 (Fri)) 9:15-13:15
| Symposium：Stem cell biology and developmental biology (in English) |
| A brief introduction： In recent years, the stem cell field has seen remarkable technological advances for recapitulating human development in vitro. It is now possible to induce germ cells from pluripotent stem cells and to recapitulate key developmental events such as somite formation and neural formation in vitro. Together with rapidly evolving omics tools such as single cell-RNA sequencing, spatial transcriptomics, and CRISPR-based cell lineage tracing, cutting-edge technology in the stem cell field is providing us with new insights into human development. In this session, we will discuss future directions in developmental biology with leading researchers in stem cells and cutting-edge omics technology, as well as basic scientists in germ development and early embryogenesis. |
| Speakers: Toshihiko Fujimori (NIBB) Shosei Yoshida (NIBB) Mitinori Saitou (Kyoto Univ.) Cantas Alev (Kyoto Univ.) Nozomu Yachie (Univ. of British Columbia / Osaka Univ.) Satoshi Yamazaki (Univ. of Tokyo) |
| Panel Discussion (in Japanese) |
| A brief introduction： 個体発生のシステム的理解を目指す発生生物学と、幹細胞の振る舞いを扱う幹細胞生物学とは密接に関わる。実際に発生システムを理解する上で、幹細胞動体は重要な素過程の一つである。しかし、国内の学会レベルで見ると両者の間には依然として多少の隔たりがあるように感じられる。今回の討論会では、幹細胞分野の著名な研究者及び若手のトップランナーを招いて、この隔たりを取り払い、両研究分野をさらに融合的に発展させるために何をすべきかについて討論したい。また、発生生物学及び幹細胞生物学分野の若手研究者や大学院生などが、未来の研究ビジョンを獲得する機会となるような、建設的な議論の場としたい。 |
| Panelist： Kiyokazu Agata (NIBB) Yoshiko Takahashi (Kyoto Univ.) Mitinori Saitou (Kyoto Univ.) Nozomu Yachie (Univ. of British Columbia / Osaka Univ.) Satoshi Yamazaki (Univ. of Tokyo) |
Symposia
Day 2 (June 20 (Thu)) 16:15-18:45
| Symposium 01：Chromatin and gene expression dynamics in development |
| Co-organized by：Society for Developmental Biology (SDB) |
| Chairpersons: Ichiro Hiratani (RIKEN BDR) Ken Cho (UC Irvine) |
| A brief introduction： The earliest phases of embryogenesis represent a period of major transitions and various lineage specification processes. These stages provide valuable insights into the regulation of chromatin and gene expression dynamics. Recent advancements in genomic tools, including low-input/single-cell multi-omics and high-resolution live-imaging technologies are accelerating the pace of new discoveries in this field. In this symposium, we will highlight researchers who are exploring the dynamic changes in chromatin and gene expression, and their underlying mechanisms during early embryogenesis. These studies encompass diverse organisms and utilize cutting-edge technologies, ranging from single-cell genomics to live imaging. |
| Speakers: Ken Cho (UC Irvine) Miler T. Lee (Univ of Pittsburgh) Yuko Sato (Tokyo Tech) Takashi Ishiuchi (Yamanashi Univ.) Ichiro Hiratani (RIKEN BDR) Takefumi Kondo (RIKEN BDR) Megan Martik (UC Berkeley) |
| Open Call for Abstracts |
| Symposium 02：New researches with unique angles |
| Co-organized by：Material properties determine body shapes and their constructions |
| Chairpersons: Noriko Funayama (Kyoto Univ.) Junpei Kuroda (Osaka Univ.) |
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A brief introduction： Now that genome sequencing, RNAseq, scRNAseq, and other comprehensive analyses have become easier, it has become very important for developmental biologists to find the unique aspects of the elegant mechanisms of living organisms to focus on. This symposium will shed light on researchers who are developing unique perspectives that will open up new research fields. Through this symposium, we hope that the audience and the presenters will share the fun of learning about the mechanisms of living organisms and the fascination of research from new perspectives, and then, realize that there are still many interesting life phenomena that have yet to be elucidated and that developmental biology is expanding even further. |
| Speakers: Maja Adamska (National univ. of Australia) Safiye E. Sarper (RIKEN BDR) Toshiya Ando (Kyoto Univ.) Mari Kawaguchi (Sophia Univ.) Alice Tsuboi (RIKEN BDR) Junpei Kuroda (Osaka Univ.) Noriko Funayama (Kyoto Univ.) |
| Symposium 03：Physics in cell and developmental biology |
| Chairpersons: Tatsuo Shibata (RIKEN BDR) Shuji Ishihara (Univ. of Tokyo) |
| A brief introduction： The emergence of biological functions at the cellular and tissue level, such as the morphogenesis of tissues and organs, involves the spatiotemporal coordination of numerous molecules and related physical and chemical processes. Physical and mathematical science approaches integrate experimental results and provide valuable insights into how such coordination is regulated within cells and tissues. This symposium highlights researches that elucidate the principles behind the emergent cellular and tissue-level functions from the perspectives of physics and mathematical sciences. |
| Speakers: Anna Erzberger (EMBL Heidelberg, Germany) Tetsuya Hiraiwa (Academia Sinica Taiwan) Daniel Riveline (IGBMC, France) Tatsuo Shibata (RIKEN BDR) Shuji Ishihara (Univ. of Tokyo) |
Day 3 (June 21 (Fri)) 9:15-11:45
| Symposium 04：Stem cell biology and developmental biology |
| Co-organized by：Institute for the Advanced Study of Human Biology, Kyoto University (ASHBi) |
| Chairpersons: Hideyuki Okano (Keio Univ.) Mototsugu Eiraku (Kyoto Univ.) |
| A brief introduction： In recent years, the stem cell field has seen remarkable technological advances for recapitulating human development in vitro. It is now possible to induce germ cells from pluripotent stem cells and to recapitulate key developmental events such as somite formation and neural formation in vitro. Together with rapidly evolving omics tools such as single cell-RNA sequencing, spatial transcriptomics, and CRISPR-based cell lineage tracing, cutting-edge technology in the stem cell field is providing us with new insights into human development. In this session, we will discuss future directions in developmental biology with leading researchers in stem cells and cutting-edge omics technology, as well as basic scientists in germ development and early embryogenesis. |
| Speakers: Toshihiko Fujimori (NIBB) Shosei Yoshida (NIBB) Mitinori Saitou (Kyoto Univ.) Cantas Alev (Kyoto Univ.) Nozomu Yachie (Univ. of British Columbia / Osaka Univ.) Satoshi Yamazaki (Univ. of Tokyo) |
Day 4 (June 22 (Sat)) 13:00-15:30
| Open Call for Abstracts |
| Symposium 05：Developmental homeostasis |
| Co-organized by：Society for Developmental Biology (SDB) |
| Chairpersons: Tadashi Uemura (Kyoto Univ.) Yukako Hattori (Kyoto Univ.) |
| A brief introduction： Various types of “noise” are ubiquitous throughout the life cycle. They encompass changeable climates and diets, unpredictable infections by pathogens, accidental tissue damage, stochastic somatic mutations, and even fluctuating structures of molecular complexes or single molecules. As a consequence, no individual life history within a species is strictly invariant, as indicated by spatiotemporal variations in embryogenesis, growth, and reproduction. Organisms have evolved buffering mechanisms in the face of such noise, thereby ensuring developmental homeostasis. In this symposium, we will highlight research that explores the roots of this homeostasis. The presenters employ multi-omics approaches in the laboratory and/or in the wild, inter-species comparative analyses, and in vivo imaging. |
| Speakers: Risa Kawaguchi (Kyoto Univ.) Asano Ishikawa (Univ. of Tokyo) Yukako Hattori (Kyoto Univ.) Soshiro Kashio (Univ. of Tokyo) Bonnie Kircher (Univ. of Texas MD Anderson Cancer Center |
| Open Call for Abstracts |
| Symposium 06：Diverse roles of cell polarity in development |
| Chairpersons: Chieko Koike (Ritsumeikan Univ.) Kazunori Sasaki (Juntendo Univ.) |
| A brief introduction： Cell polarity, an asymmetric distribution of cellular and molecular components along an axis, plays a fundamental role in various aspects of development and its dysfunction causes developmental defects. In this symposium, we would like to introduce and discuss the latest advances in diverse roles of cell polarity and their regulatory mechanisms during tissue morphogenesis and cell fate controls. The topics are wide-ranging, including different model organisms and systems such as nematode oogenesis, fly midgut homeostasis, frog thyroid gland morphogenesis, and mouse retinal cell fate determination. This symposium will be a valuable opportunity for participants and offer profound insights into the extensive biological significance of cell polarity in development. |
| Speakers: Fumio Motegi (Hokkaido Univ.) Yasushi Izumi (NIPS) Asako Shindo (Kumamoto Univ.) Akiko Ueno (Ritsumeikan Univ.) Kazunori Sasaki (Juntendo Univ.) |
| Open Call for Abstracts |
| Symposium 07：Genetic and developmental bases for mammalian neocortical evolution |
| Chairpersons: Tadashi Nomura (KIT) Chiaki Maruyama (TMIMS) |
| A brief introduction： The mammalian neocortex is a unique neuroanatomical structure characterized by tangential surface expansion and six layers. Neocortical expansion is accelerated in primates and humans and is thought to contribute to the evolution of human-specific cognitive functions. However, the cellular and molecular mechanisms underlying the evolution of the neocortex remain to be elucidated. This symposium will focus on the diverse developmental mechanisms predicted to have contributed to the evolution of the mammalian neocortex. Selected speakers will present recent findings on species-specific characteristics of neural progenitors, unique cellular and molecular properties of layer-specific neurons, and human-specific genetic bases that contributed to neocortical expansion. Lively discussions with the audience are expected to enhance our understanding of the developmental basis for the evolution of the mammalian neocortex. |
| Speakers: Ikuo Suzuki (Univ. of Tokyo) Carina Hanashima (Waseda Univ.) Chiaki Maruyama (TMIMS) Tadashi Nomura (KIT) Jun Hatakeyama (Kumamoto Univ.) Debra Silver (Duke Univ.) |
Day 0 (June 17 (Mon) - 18 (Tue))
| Open Call for Abstracts |
| International symposium on Mechanical self-transformation of Living Systems |
| Venue : Kyoto Rekisaikan - Kyoto Institute, Library and Archives - Registration fee: Free of charge |
| https://www.igm.hokudai.ac.jp/self-organization-in-cells-and-tissues/index.html |