Session Details
[2P-1]Poster Presentation
Thu. Nov 28, 2024 12:55 PM - 2:55 PM JST
Thu. Nov 28, 2024 3:55 AM - 5:55 AM UTC
Thu. Nov 28, 2024 3:55 AM - 5:55 AM UTC
Poster & Exhibition Venue 1 (Marine Messe Fukuoka Hall A, 1F)
1.Molecular
- a.Genome/Gene/Nucleic Acid
- b.DNA replication
- c.Recombination/Mutation/Repair
- d.Epigenetics/Chromatin
- e.Transcription
- f.RNA/Ribonucleoprotein
- g.Translation
- h.Protein
- i.Carbohydrate/Lipid/Metabolite
- j.Molecular Evolution/Comparative Genomics
- l.Others
2.Cell
- a.Chromosome/Nuclear Body
- b.Phase Separation
- c.Protein Processing/Transport/Localization
- d.Cytoplasmic Membranous Organelle
- e.Cell Adhesion/Cell Motility/Extracellular Matrix
- f.Cell Membrane/Cytoskeleton
- g.Cell Proliferation/Division/Cell Cycle
- h.Signal Transduction (Post Translational Modification)
- i.Signal Transduction (Bioactive Substance)
- j.Cell Death
- k.Others
- a.Genome/Gene/Nucleic Acid
- b.DNA replication
- c.Recombination/Mutation/Repair
- d.Epigenetics/Chromatin
- e.Transcription
- f.RNA/Ribonucleoprotein
- g.Translation
- h.Protein
- i.Carbohydrate/Lipid/Metabolite
- j.Molecular Evolution/Comparative Genomics
- l.Others
2.Cell
- a.Chromosome/Nuclear Body
- b.Phase Separation
- c.Protein Processing/Transport/Localization
- d.Cytoplasmic Membranous Organelle
- e.Cell Adhesion/Cell Motility/Extracellular Matrix
- f.Cell Membrane/Cytoskeleton
- g.Cell Proliferation/Division/Cell Cycle
- h.Signal Transduction (Post Translational Modification)
- i.Signal Transduction (Bioactive Substance)
- j.Cell Death
- k.Others
[2P-001]Chemical modifications of 5'-tailed duplex’, an artificial nuclease-free gene-editing tool
○Taiki Kato1, Ryotaro Kamitsubo1, Takao Shoji2, Makoto Koizumi2, Hidehiko Kawai1, Hiroyuki Kamiya1 (1. Grad. Sch. Biomed. Hlth. Sci., Hiroshima Univ., 2. Modality Res. Lab. I, Daiichi Sankyo Co., Ltd.)
[2P-002]Analysis of mutation induction by chemical modifications of single-stranded DNA for gene editing
○Haoting Tsai1, Takao Shoji2, Makoto Koizumi2, Hidehiko Kawai1, Hiroyuki Kamiya1 (1. Grad. Sch. Biomed. Hlth. Sci., Hiroshima Univ., 2. Modality Res. Lab. I, Daiichi Sankyo Co., Ltd.)
[2P-003]Female infertility in mice caused by chromosomal inversion at the HoxD locus
○Katsuki Hirano1, Satoru Iwata2,3,4,5, Manabu Takamatsu6, Miki Nagahara3, Takashi Iwamoto1,2,3 (1. Department of Biomedical Sciences, Chubu University Graduate School of Life and Health Sciences, 2. Department of Biomedical, College of Life and Health Science, Chubu University, 3. Center for Education in Laboratory Animal Research, Chubu University, 4. College of Bioscience and Biotechnology, Chubu University, 5. Center for Mathematical Science and Artificial Intelligence, Chubu University, 6. Division of Pathology, The Cancer Institute Japanese Foundation for Cancer Research)
[2P-004]RUNX1 maintains hematopoietic stem cell integrity through the formation of transcriptional repressive complex against LINE-1 (TRCL)
○Bibek Dutta1, Michelle Meng Huang Mok1, Haruhito Totani1, Chen Yong Tham1, Akiko Niibori-Nmabu1, Arusyak Ivanyan2, Chu Guo Chu4, Chng Wee-Joo1, Kimi Araki3, Kazuya Iwamoto4, Goro Sashida2, Motomi Osato1,2,5 (1. Cancer Science Institute, National University of Singapore, 2. International Research Center for Medical Sciences, Kumamoto University, 3. Division of Developmental Genetics, Institute of Resource Development and Analysis, Kumamoto University, 4. Department of Molecular Brain Science, Graduate School of Medical Sciences, Kumamoto University, 5. 5Department General Internal Medicine, Kumamoto Kenhoku Hospital.)
[2P-005]Mechanisms for anticancer effects of G-quadruplex ligands through translation inhibition
○Risa Ito1,2, Sachiko Okabe1, Yuna Mogi1,2, Chuya Nakanishi1,2, Yuichi Shichino3, Shintaro Iwasaki2,3, Kazuo Shin-ya4, Kazuo Nagasawa5, Hiroyuki Seimiya1,2 (1. Div. Mol. Biother., JFCR Cancer Chemother. Ctr., 2. Dept. Comput. Sci. Med. Sci., Grad. Sch. Frontier Sci., Univ. Tokyo., 3. Div. RNA Systems Biochem. Lab., RIKEN Clust. Pioneer. Res., 4. Biomed. Info. Res. Ctr., Natl. Inst. AIST, 5. Biomed. Fac. Technol., Tokyo Univ. Agric. Technol)
[2P-006]Elucidation of the mechanisms of transcription termination and nuclear body formation by LEC components ZC3H8
○Keisuke Noguchi1, Risa Onizawa1, Ryota Abe1, Toru Sengoku2, Kazuhiro Ogata2, Yoko Ike1, Yoko Ino3, Yayoi Kimura3, Yuko Nobe4, Satoru Taoka4, Akio Masuda5, Hidefumi Suzuki1, Hidehisa Takahashi1 (1. Dept. of Mol. Biol., Grad. Sch. of Med. Sci., Yokohama city univ., 2. Dept. of Biolchem., Grad. Sch. of Med. Sci., Yokohama city univ., 3. Adv. Med. Res. Cent., Yokohama City Univ., 4. Dept. of Chem. Grad. Sch. of Sci., Tokyo Metropolitan Univ., 5. Dept. of Nurosci. Grad. Sch. of Med., Nagoya Univ.)
[2P-007]Analysis of splicing abnormalities due to CTG trinucleotide repeat expansion in Fuchs endothelial corneal dystrophy
○Taichi Yuasa1, Naoki Okumura1, Soichiro Inagaki1, Tatsuya Nakagawa1, Yuichi Tokuda2, Masakazu Nakano2, Kei Tashiro2, Theofilos Tourtas3, Ursula Schlötzer-Schrehardt3, Friedrich Kruse3, Noriko Koizumi1 (1. Department of Biomedical Engineering, Faculty of Life and Medical Sciences, Doshisha University, 2. Department of Genomic Medical Sciences, Kyoto Prefectural University of Medicine, 3. Department of Ophthalmology, University of Erlangen-Nürnberg)
[2P-008]Creation of naturally occurring Human leukocyte antigen (HLA) null variants using Prime Editing in human induced pluripotent stem cells (iPSCs)
○Hafiza Ishrat Fatima1,2, Gabriel Martínez-Gálvez1, Ryo Niwa1,2, Suji Lee1, Shihoko Endo1,3, Sayaka Kayumi1, Mikiko Fukuda1, Knut Woltjen1 (1. Center for iPS cell Research and Application (CiRA), Kyoto University, Japan, 2. Graduate School of Medicine, Kyoto University, Japan, 3. Department of Medicine, Kyoto University, Japan)
[2P-009]Molecular Mechanisms of Polycomb-mediated Regulation of Higher-Order Genome Structure
○Ryo Onishi1 (1. RIKEN Center for Integrative Medical Sciences)
[2P-010(2AS-02-06)]Automating DNA Design Using Conversational AI
○Hideto Mori1 (1. Osaka Univ.)
[2P-011(2AS-02-07)]Gene prediction and functional annotation for de novo genome assembly using BRAKER3 and Fanflow4Insects
○Kouhei Toga1,2, Bono Hidemasa1,2 (1. Hiroshima Univ., 2. Grad.Sch. of Inte. Sci. for Life, Hiroshima Univ.)
[2P-012]Elucidation of ligand-independent vitamin D receptor mechanisms in the skin
○Satoko Kise1, Toshiyuki Sakaki2, Hiroyuki Kimura1, Seigo Kinuya1, Kaori Yasuda2 (1. Kanazawa Univ., 2. Toyama Prefectural Univ.)
[2P-013]Expression of glycolytic genes in colorectal cancer cells under the effect of radiation
○Matthew Y H Lau1,2, Ka Wai, Helen Law1 (1. The Hong Kong Polytechnic University, 2. The Hong Kong Metropolitan University)
[2P-014]Functional analysis of genomic enhancers that regulate the expression of mit ochondrial chaperone in HepG2
○Riyo Konishi-Maeda1, Shinpei Kawaoka1,2 (1. Kyoto University, 2. Tohoku University)
[2P-015]Evaluation of impurities in adeno-associated virus vector production using plasmid DNA and LCC-DNA
○Kyoko Masumi Koizumi1,2, Emi Ito Kudo1, Shota Hirayama3, Koki Sasamoto3, Teruyuki Nishi1,3, Kazuhisa Uchida1,2 (1. Kobe Univ., 2. MAB, 3. Kaneka Corp.)
[2P-016]Towards telomere-to-telomere genome for the Pv11 cell line from a desiccation tolerant midge
○Yuki Yoshida1, Takahiro Kikawada1,2 (1. NIAS, NARO, 2. Grad. Sch. Frontier Sci., Univ. Tokyo)
[2P-017]Characteristics of specific 3D genome structures and their regulatory regions in human healthy-derived and disease-derived cells
○Ikumi Haraoka1, Akinori awazu1 (1. Graduate School of Integrated Sciences for Life)
[2P-018]Development of a recombinase-mediated exchangeable gene trap system in zebrafish
○Kimiko Saka1, Koichi Kawakami1,2 (1. Lab of Mol. and Dev. Biol., NIG, 2. Genet., Grad. Inst. for Adv. Stud., SOKENDAI)
[2P-019]Single-molecule measurement of biomolecular dynamics through the control of fluorescence blinking
○Kiyohiko Kawai1, Mamoru Fujitsuka2, Atsushi Maruyama1, Yohei Kondo1 (1. Tokyo Tech., 2. Osaka Univ.)
[2P-020]Development and Application of Gene Expression Systems in the Model Arthropod Common House Spider (Parasteatoda tepidariorum)
○Koh Nakagawa1,2,3, Yasuko Akiyama-Oda1,5, Nobuaki Kono2,3,4, Hiroki Oda1,6 (1. JT Biohistory Research Hall, 2. Graduate School of Media and Governance, Keio University, 3. Institute for Advanced Biosciences, Keio University, 4. Faculty of Environment and Information Studies, Keio University, 5. Osaka Medical and Pharmaceutical University, 6. Graduate School of Science, Osaka University)
[2P-021]DNA double-strand break repair regulated by protein arginine methyltransferases
○Yurina Abe1, Yuina Tsuchiya1, Ryotaro Nishi1 (1. Mol. Biol. Lab., Grad. Sch. Bionics, Tokyo Uni. Tech.)
[2P-022]Whole genome analysis of Paramecium by long-read sequencing
○Masato Tachibana1, Shintaro Maeno1, Hideo Dora2, Kenta Watanabe3, Takashi Shimizu3, Masahisa Watarai3 (1. Org. Res. Ini. Yamaguchi Univ., 2. Shizu Ins. Ana. Cen. Shizuoka Univ., 3. Joi. Fac. Vet. Med. Yamaguchi Univ.)
[2P-023]Analysis and minimization of the origin of transfer region for conjugation from Escherichia coli to Bacillus subtilis
○Taiki Kanzaki1, Shunsuke Inomata1, Yuta Fukada1, Masakazu Kataoka1 (1. Shinshu Univ. Eng. BioMed)
[2P-024]BLAST_TSN, a target-specific nucleotide sequence search tool
○Jumpei NARUSHIMA Narushima1, Miyu Sugino1, Keisuke Soga1, Satoko Yoshiba1, Norihito Shibata1 (1. National Institute of Health Sciences)
[2P-025]Conversion of polyploid and alloploid Saccharomyces sensu stricto strains to leu2 mutants by genome DNA editing
○Kazuya Kiyokawa1,2, Tetsushi Sakuma1, Kazuki Moriguchi1, Minetaka Sugiyama3, Takeshi Akao4, Takashi Yamamoto1,2, Katsunori Suzuki1 (1. Grad. Sch. Integr. Sci. Life, Hiroshima Univ., 2. Genome innov. center, Hiroshima Univ., 3. Faculty of Life Sci., Hiroshima Inst. of Tech., 4. NRIB)
[2P-026]Identification and functional exploration of long non-coding RNAs important in human evolution
○Mine Watanabe1, Takashi Makino1 (1. Tohoku University)
[2P-027]Non-homologous end joining (NHEJ)/ homology-directed repair (HDR) visualized mice
○Takuro Horii1, Mika Kimura1, Ryosuke Kobayashi2, Sumiyo Morita1, Izuho Hatada1,3 (1. Gunma Univ., 2. Rakuno Gakuen Univ., 3. GIAR)
[2P-028]Development of Sanger Sequencing Analysis Software for Highly Sensitive Detection of Large Deletions Induced by Genome Editing
○Kazuki Nakamae1,2, Saya Ide1,2, Nagaki Ohnuki1,2, Yoshiko Nakagawa2, Keisuke Okuhara1,2, Hidemasa Bono1,3 (1. Genome Editing Innovation Center, Hiroshima University, 2. Research and Development Department, PtBio Inc., 3. Graduate School of Integrated Sciences for Life, Hiroshima University)
[2P-029]Molecular mechanisms of short-term and long-term temperature responses in Madagascar ground gecko
○Fuku Sakamoto1, Shunsuke Kanamori1, Félix Rakotondraparany2, Takashi Makino1, Masakado Kawata1 (1. Tohoku Univ., 2. Département Zoologie et Biodiversité Animale, Université d'Antananarivo)
[2P-030]Blistered wing mutant, NK25 is a new allele of a blistered caused by the insertion of a defective micropia-like retrotransposon.
○Yasuko Kato1, Yuzu Hashizume1, Nokuthula Sibonokuhleq Knonyane1, Haruya Matsugi1, Masanobu Itoh1 (1. Department of Applied Biology, Kyoto Institute of Technology)
[2P-031]Pathogenic annotation of variants of unknown significance (VUS) based on pan-kinase mutational profile
○Teruki Tsunashima1,2, Takashi Kohno2, Takashi Nakaoku2, Kohsuke Maruyama2, Shigenari Nukaga2, Yu Hamaguchi2 (1. Tokyo Univ of Technology, 2. National Cancer Center Research Institute)
[2P-032]A new approach for generating Flox mice using Cas9 nickase
○Shunsuke Takarabe1, Ryosuke Kobayashi2, Yui Kawata3, Atsuko Kageyama3, Naomi Kashiwazaki1,3, Junya Ito1,3, Jumpei Terakawa1,3 (1. AzabuLaboratory of Animal Reproduction, Graduate School of Veterinary Sciences, Azabu University, 2. Department of Veterinary Medicine, Rakuno Gakuen University, 3. School of Veterinary Medicine, Azabu University)
[2P-033]Simple and efficient procedures of genome library construction for systematic screening in yeast
○Keito Abe1, Hisao Moriya1 (1. Okayama University)
[2P-034]Analysis of the function of cohesin binding sites negatively correlated with gene expression
○Yuya Nagaoka1, Ryuichiro Nakato1 (1. The University of Tokyo)
[2P-035]Development of a gene regulation system for non-cytotoxic herpes simplex virus vector by gene editing
○Yasunobu Maruoka1, Yoshitaka Miyagawa1, Yuriko Sato1, Mashito Sakai1, Takashi Okada2 (1. Dept. of Biochem. Mol. Biol., NIPPON MED SCH, 2. Div. of Mol. Med. Genet., Univ. of TOKYO)
[2P-036]Construction of Baculoviruses Deficient in Non-Essential Gene Clusters for Improved Recombinant Protein Productivity
○Ayaka Yamaguchi1, Takeru Ebihara1, Hiroaki Mon2, Jaeman Lee2, Ryosuke Fujita2, Masato Hino2, Takahiro Kusakabe2 (1. Kyushu Univ. Graduate School of Bioresource and Bioenvironmental Sciences, 2. Kyushu Univ. Faculty of Agriculture)
[2P-037]Optimization of saturation genome editing for effective SNP analysis
○Taiji Hamada1, Seiya Yokoyama1, Kei Matsuo1, Toshiaki Akahane1, Tatsuhiko Furukawa1, Akihide Tanimoto1 (1. Kagoshima University)
[2P-038]Evaluation of Machine Learning procedures for feature selection and classification of Ebola disease phenotypes using Collaborative Cross-mice omics data.
○Magdaline Akinyi Otieno1, Kenta Suzuki2, Toyoyuki Takada2, Hiroshi Masuya2 (1. Univ. Tsukuba/ RIKEN BRC, 2. RIKEN BRC)
[2P-040]MicroRNA extraction using a combination of miRNA Enhance Buffer and spin column method and characterization using a next-generation sequencer
○Azumi Naruse1, Arizumi Kikuchi1, Kenichi Nonaka1,2, Kimiaki Takagi3, Kentaro Suzuki4, Yoshifumi Yutoh5 (1. Daiyukai Research Institute for Medical Science, 2. Daiyukai General Hospital/Surgery, 3. Daiyukai General Hospital/Urology, 4. Daiyukai General Hospital/ Clinical laboratory, 5. KANTO CHEMICAL CO.,INC.)
[2P-041(2MS-09-04)]Target-AID base editing enables precise genetic manipulation in lactic acid bacteria
○Hitoshi Mitsunobu1, Yudai Kita1, Yumiko Nambu2, Shoko Miyazaki2, Kensuke Nakajima2, Keiji Nishida1 (1. Kobe University, 2. Bio Palette Co., Ltd.)
[2P-042]Translational inhibition by photoresponsive α-haloaldehyde-conjugated oligonucleotides
○Riena Sengoku1, Kentaro Kobata1, Yuta Sugihara1, Yuki Nakata1, Kazuya Matsuo1, Tomonori Waku1, Akio Kobori1 (1. Kyoto Institute of Technology)
[2P-043]Cohesin stabilizes promoter-proximal pausing and transcription elongation
○Shoin Tei1, Masashige Bando1, Katsuhiko Shirahige1,2 (1. IQB, Univ. of Tokyo, 2. Karolinska Institutet, Sweden)
[2P-044]Identification of anisotropy in chromosome dynamics by principal component analysis using integrated spatial genomics
○Takuya Nara1, Haruko Takahashi1, Akinori Awazu1, Yutaka Kikuchi1 (1. Hiroshima University)
[2P-045]Exploring cell-cell interactions involved in horizontal gene transfer between symbiotic algae from corals and giant clams
○Eiichi Shoguchi1 (1. OIST)
[2P-046]The role of nuclear pore in stabilizaing of ribosomal RNA gene.
○Yamato Okada1, Masahiko Harata1, Chihiro Horigome1 (1. Tohoku university)
[2P-047]Development of Koshihikari with genes that are resilient against climate change and insect resistance
○Minami Miki1, Motonori Tomita1 (1. Res. Inst. Green Sci. & Technol., Shizuoka Univ.)
[2P-048]Development of Koshihikari with genes that are resilient against climate change and disease resistance
○Soyo Kojima1, Motonori Tomita1 (1. Res. Inst. Green Sci. & Technol., Shizuoka Univ.)
[2P-049]Development of a late-flowering, resilient, high-yielding isogenic Koshihikari, that avoids high-temperature ripening
○Hiroki Sugihara1, Motonori Tomita1 (1. Res. Inst. Green Sci. & Technol., Shizuoka Univ.)
[2P-050]Development of the Specific Nucleic Acid Aptamer (SureGrip Aptamer) Technology
○Makoto Miyagishi1 (1. National Institute of Andvanced Industrial Science and Technology)
[2P-051]Investigating the role of Nse5/6 in the chromosomal association of Smc5/6
○Jumpei Fukute1,2, Jeppsson Kristian1,2 (1. IQB, The univ. of Tokyo, 2. Karolinska Institutet)
[2P-052]Molecular design of substrate recognition sequences in a DNAzyme
○Natsuki Doi1, Teru Biwata1, Nae Sakimoto2, Junji kawakami1 (1. FIRST, Konan University, 2. KOLOT)
[2P-053]Evaluation of genomic DNA analysis using Ultra-Long Sequencing
○Yugo Matsuo1, Masahide Seki1, Yutaka Suzuki1 (1. Dept. of Comp. Biol. and Med. Sci., Grad. Sch. of Front. Sci., Univ. of Tokyo)
[2P-054]Information about celluler functions engraved in genomic DNA
○Futaha Yatsuda1, Ryoichi Miyanishi1, Koki Hirosawa1, Kenichi Hasegawa1, Kenichiro Hoashi1, Ryoiti Kiyama1 (1. Kyushu Sangyo Univ.)
[2P-055]Exploration of novel transcription factors regulating the Sox9 gene in the Amami spiny rat, Tokudaia osimensis
○Shoichiro Mitsukawa1, Shusei Mizushima1,2, Asato Kuroiwa1,2 (1. Grad. Sch. Life Sci., Hokkaido Univ., 2. Fac. Sci., Hokkaido Univ.)
[2P-056]Elucidation of the Mechanism by which Histone Acetyltransferase HBO1 promotes DNA Replication Origin Licensing in Human Cells
○Yuuki Yamamoto1, Ryotaro Mori1, Miyako Shiraishi1, Yasunori Noguchi1, Youko Katsuki1, Torahiko Higashi1, Masatoshi Fujita1 (1. Kyushu Univ.)
[2P-057]Analysis of interacting factors of the Cohesin loader Scc2–Scc4 complex
○Ryuta Kodama1, Kei-ichiro Ishiguro2, Tatsuro Takahashi3 (1. Graduate School of Systems Life Sciences, Kyushu University, 2. Institute of Molecular Embryology and Genetics (IMEG), Kumamoto University, 3. Faculty of Science, Kyushu University)
[2P-058]Structural analysis of archaeal replication mechanism by family D DNA polymerase
○Yumi Hirose1, Keisuke Oki1, Takeshi Yamagami1, Shunsuke Matsumoto1, Shigenori Iwai2, Sonoko Ishino1, Yoshizumi Ishino1, Tomoyuki Numata1 (1. Graduate School of Bioresource and Bioenvironmental Science, Kyushu university, 2. Graduate School of Engineering Science, Osaka university)
[2P-059]Investigation of HMGA1 regulating DNA replication fork maintenance mechanism
○Syoju Endo1,2, Taichi Igarashi2, Kimiyoshi Yano2, Bunsyo Shiotani2 (1. Dept. of NCC Cancer Sci., Grad. Sch. of Med. & Dent. Sci., Tokyo Med. and Dent. Univ., 2. Lab. of Genome Stress Signal., Natl. Cancer Ctr. Res. Inst.)
[2P-060]Plasmid DNA replication initiated by CyRep proteins and small RNA
○Minori Sakata1, Kazuma Ohdate1, Kaisei Maeda2, Yutaka Sakamaki1, Kaori Nimura-Matsune1, Ryudo Ohbayashi3, Wolfgang Hess4, Satoru Watanabe1 (1. Tokyo Univ. Agric., 2. Tokyo Inst. Technol., 3. Shizuoka Univ., 4. Univ. Freiburg)
[2P-061]Roles of G-quadruplex- and ORCA/LRWD1-binding activities on chromatin binding of human ORC
○Shou Waga1, Mayuko Iwata1, Minami Takano1, Chisa Nishio1, Kana Shimada1 (1. Japan Women's Univ.)
[2P-062]Intracellular calcium ion response to the initiation of DNA re-replication is critical for cell survival
○Mirai Uno1, Koske Iida1, Miku Nakamura1, Yasushi Shiomi1, Akiyo Hayashi1, Hideo Nishitani1 (1. Univ. of Hyogo)
[2P-063]Mechanism of chromatin remodeling that regulates DNA damage recognition for nucleotide excision repair.
○Kanae Fujiwara1,2, Kazuki Tsuchida1,2, Masayuki Kusakabe1,2,3, Kanako Kusao1,2, Satoru Yakuwa1,3, Masayuki Yokoi1,2,3, Wataru Sakai1,2,3, Kaoru Sugasawa1,2,3 (1. Biosignal Res. Ctr., Kobe Univ, 2. Grad. Sch. Sci., Kobe Univ, 3. Fac. Sci., Kobe Univ)
[2P-064]Enhanced erythrocyte differentiation by microhomology-mediated gene editing of a naturally occurring EPOR mutation in human iPS cells
○Sayaka Kayumi1, Miyuki Ono1, Suji Lee1, Yoko Nishinaka-Arai1, Megumu K. Saito1, Knut Woltjen1 (1. CiRA, Kyoto Univ.)
[2P-065]Functional analysis of ARID1A in DNA repair
○Usaki Arai1, Shinta Saito1, Noritaka Adachi1 (1. Grad. Sch. Nanobiosci., Yokohama City Univ.)
[2P-066(2MS-08-03)]Molecular mechanism of DNA end resection and repair pathway choice in DNA double-strand break repair
○Miki Shinohara1,2, Tomoki Tamai1, Giordano Reginato3, Ryusei Ojiri1, Kenta Sasada1, Kenichiro Matsuzaki1, Petr Cejka3, Valérie Borde4, Katsunori Sugimoto5 (1. Grad. Schl. Agri., Kindai Univ., 2. ATRI, Kindai Univ., 3. Università della Svizzera italiana (USI), 4. Institut Curie, 5. State University of New Jersey)
[2P-067]Mechanism of the replication past an oxidative RNA lesion catalyzed by SARS-CoV-2 RNA-dependent RNA polymerase
○Masataka Akagawa1, Petr Grúz2, Kaoru Sugasawa3, Kiyoe Ura1, Akira Sassa1 (1. Graduate School of Science, Chiba University, 2. Division of Genome Safety Science, National Institute of Health Sciences, 3. Biosignal Research Center, Kobe University)
[2P-068(2MS-08-02)]Blood cell analysis of BRCA2 using targeted molecular degradation in mice
○Kosuke Yamazaki1,2, Tomohiro Iguchi2, Midori Yamaguchi3, Manami Sano2, Kazuto Takayasu2, Kosuke Yusa4, Masato Kanemaki5,6,7, Ichiro Taniuchi8, Hisao Masai1,2, Hiroyuki Sasanuma2 (1. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, 2. Department of Basic Medical Sciences, Tokyo Metropolitan Institute of Medical Science, 3. Laboratory for Transgenic Technology, Center for Basic Technology Research, Tokyo Metropolitan Institute of Medical Science, 4. Stem Cell Genetics, Institute for Frontier Life and Medical Sciences, Kyoto University, 5. Department of Chromosome Science, National Institute of Genetics, Research Organization of Information and Systems (ROIS), 6. Department of Genetics, The Graduate University for Advanced Studies (SOKENDAI), 7. Department of Biological Science, The University of Tokyo, 8. Laboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences)
[2P-069]The different of viral growth due to the amino acid mutations within ORF1ab region of SARS-CoV-2 variants
○Yoshiro Sugiura1, Tatsuki Takahashi1, Kenta Shimizu1, Sodbayasgalan Amarbayasgalan1, Enkhjin Dorjsuren1, Wataru Kamitani1 (1. Department of Infectious Diseases and Host Defense, Graduate School of Medicine, Gunma University)
[2P-070]Creation of gene knockout hamsters using the i-GONAD
○Yuko Yamauchi1, Kazuto Yoshimi1, Michiko Hirose2, Atsuo Ogura2, Tomoji Mashimo1 (1. IMSUT, Univ. Tokyo, 2. RIKEN BRC)
[2P-071]The Multifaceted Role of an Epithelial-Mesenchymal Transition-Inducing Transcription Factor in Cancer Cell Malignancy
○Minoru Terashima1, Ryusuke Suzuki2, Kusuma Suphakhong2, Takumi Nishiuchi3, Shinichi Horike4, Tatsunori Nishimura5, Shoichiro Tange6, Akihiko Ishimura2,7, Takeshi Suzuki2,7 (1. Kumamoto Univ., IRCMS, 2. Kanazawa Univ., CRI, Div. Func. Gen., 3. Kanazawa Univ., RCEMHD, Div. Func. Gen., 4. Kanazawa Univ., RCEMHD, Div. Integr. Omics Res., 5. Nagoya Univ., Grad. Sch. Med., Div. Cancer Biol., 6. Sapporo Med. Univ., Res. Inst. Front. Med., Med. Genome Sci., 7. Kanazawa Univ., INFINITI, Mol. Therap. Tgt. Res.)
[2P-072]Changes in repair pathways of radiation-induced DNA double-strand breaks at the midblastula transition in Xenopus embryo
○Naoto Shimizu1,2, Ryosuke Morozumi2, Kouhei Tamura2, Makoto Nakamura2,3, Atsushi Suzuki2, Hiroko Ishiniwa4, Hiroshi Ide2, Masataka Tsuda1,2 (1. National Institute of Health Sciences, 2. Hiroshima University, 3. University of California, San Francisco, 4. Fukushima University)
[2P-073]Comprehensive analysis focusing on RAD51 foci formation ability among esophageal cancer cell lines
○Ryuta Suzuki1, Kohei Tateno1,2, Ken Okuda1, Shunji Haruna1, Mayu Isono1, Ryota Hayashi1, Hikaru Okumura1, Yuki Uchihara1, Atsushi Shibata1 (1. Keio Univ., 2. Gunma Univ.)
[2P-074]Analysis of DNA-binding sites required for ssDNA annealing of Rad52 of S. cerevisiae
○Kentaro Yoshioka1, Naoto Arai1,2 (1. Appl. Life Sci. Grad. Sch. of Biores. Scie., Nihon Univ., 2. Dpt. of Biosci. Coll. of Biores. Sci. Nihon Univ.)
[2P-075]The mechanisms of the recruitment of SLX4-XPF nuclease complex in the response to replication stress induced by lacO-LacI interaction
○Yoko Katsuki1, Takuma Okano1, Soki Haruta1, Junpei Fujii1, Tomoki Matsumura1, Yasunori Noguchi1, Miyako Shiraishi1, Kazumasa Yoshida1, Masatoshi Fujita1 (1. Grad. Sch. Pharm. Sci., Kyushu Univ.)
[2P-076]Cryo-EM structure of the large serine recombinase
○Teppei Soma1, Masahiro Hiraizumi1, Sae Okazaki2, Yukari Isayama3, Kazuki Kato3, Keitaro Yamashita1,2, Hiroshi Nishimasu1,2 (1. Dept. of Chem. & Biotech., Grad. Sch. of Eng., Univ. of Tokyo, 2. Struct. Biol. Div., RCAST, The Univ. of Tokyo, 3. Dept. of Mol. Immu., Grad. Sch. of Med. Dent., Tokyo Med. Dent. Univ.)
[2P-077]Genomic structure analysis of radiation-induced rat mammary cancer
○Atsuko Ishikawa1, Yuzuki Nakamura1,2, Yoshiko Amasaki1, Shizuko Kakinuma1, Takamitsu Morioka1, Tatsuhiko Imaoka1, Kazuhiro Daino1 (1. QST NIRS, 2. TMU)
[2P-078]Genome editing of JAK2 V617F mutation for polycythemia vera by Trans-splicing
○Haruka Ae1 (1. Seikei University)
[2P-079]Comparison of mechanisms for coping with DNA damage stress in Rubrobacter radiotolerans and Deinococcus radiodurans
○Ikki Kawasaki1, Aya Kubo2, Issay Narumi1,2,3 (1. Grad. Sch. Life Sci., Toyo Univ., 2. BRRP, Toyo Univ., 3. Facl. Life Sci., Toyo Univ.)
[2P-080]DNA-binding, DNA-unwinding, and oligomerization dynamics of the nonhexameric Escherichia coli UvrD helicase lacking C-terminal amino acids
○Hiroaki Yokota1 (1. Grad. Sch. Creation New Photon. Indust.)
[2P-082]Effect of ALDH3A2 deficiency on genome stability
○Tomoya Hotani1,2, Taro Okada3, Taketoshi Kajimoto3, Masakazu Shinohara3, Masayuki Yokoi1,2, Kaoru Sugasawa1,2, Wataru Sakai1,2 (1. Biosignal Res. Ctr., Kobe Univ., 2. Grad. Sch. Sci., Kobe Univ., 3. Grad. Sch. Med., Kobe Univ.)
[2P-083]Smarcad1 facilitates the mismatch repair-dependent O6-methylguanine response
○Karin Shigenobu Ueno1, Reihi Sakamoto1, Eiichiro Kanatsu1, Tatsuro Takahashi2 (1. Grad. Sch. of System Life Sciences., Kyushu Univ., 2. Fac. of Sci., Kyushu Univ.)
[2P-084]Functional and structural analysis of the DNA end-resection complex from hyperthermophilic archaeon Thermococcus kodakarensis.
○Keishiro Uda1, Takeshi Yamagami1, Sonoko Ishino1, Shunsuke Matsumoto1, Yoshizumi Ishino1, Tomoyuki Numata1 (1. Graduate School of Bioresource and Bioenvironmental Science, Kyushu University)
[2P-085]Repair mechanisms and biological effects of DNA damage caused by endogenous aldehydes
○Yasuyoshi Oka1, Tomoo Ogi1 (1. Nagoya University)
[2P-086]Characterization and regulation of cell cycle-independent noncanonical gene targeting
○Shinta Saito1, Noritaka Adachi1 (1. Grad. Sch. Nanobiosci., Yokohama City Univ.)
[2P-087]Werner helicase and MutLα endonuclease control the fidelity of single-strand annealing
○Yoshitaka Kawasoe1, Satomi Oda2, Aya Sakazume3, Ryoko Hisamochi3, Taisei Miyata3, Tatsuro Takahashi1 (1. Faculty of Science, Kyushu University, 2. Graduate School of Science, Osaka University, 3. Graduate School of Systems Life Sciences, Kyushu University)
[2P-088]Expression analysis of Kinesin mutation detected in clinically separated breast cancer
○Naruyo Nishimura1, Kenji Watanabe1, Shigeru Yamamoto2, Noriko Maeda2, Takayuki Ohnishi1, Makiko Nakagawa1, Keishiro Isayama1, Hiroaki Nagano2, Yoichi Mizukami1 (1. Institute of Gene Research, Science Research Center, Univ. of Yamaguchi, 2. Dept. of Digestive Surgery and Surgical Oncology, Grad. Sch. of Med., Univ. of Yamaguchi)
[2P-089]Molecular mechanism of the DSB repair pathway choice at heterochromatin region through the yeast silencing factor Sir3
○Kenta Sasada1, Kenichiro Matsuzaki1, Miki Shinohara1,2 (1. Advanced Bioscience, Graduate School of Agriculture, Kindai University, 2. Agricultural Technology and Innovation Research Institute, Kindai University)
[2P-090]Mismatch DNA repair system effectively maintains the integrity of the genome in germline cells
○Noriko Takano1, Kyoko Hidaka1,2, Mizuki Ohno1 (1. Kyushu University, 2. University of Kitakyushu)
[2P-091]Artificial centromeric DNA hypermethylation induces abnormal 2-cell gene expression and developmental arrest in mouse preimplantation embryo.
○Taiga Yamazaki1, Haruka Jogan2, Hiroki Ikeda3, Yu Hatano4, Sakiko Katagiri2, Kazuki Kurimoto3, Kazuo Yamagata2 (1. Med. Ctr, Kitasato Univ., 2. BOST, Kindai Univ., 3. Sch. of Med., Nara Med. Univ., 4. Fac. of Env. Sci., Univ. of Yamanashi)
[2P-092]Artificial centromeric DNA hypermethylation causes developmental arrest without changes to heterochromatin formation in mouse preimplantation embryo.
○Haruka Jogan1, Taiga Yamazaki2, Yu Hatano3, Sakiko Katagiri1, Kazuo Yamagata1 (1. BOST., Kindai Univ., 2. Med. Ctr, Kitasato Univ., 3. Fac. of Env. Sci., Univ. of Yamanashi)
[2P-093]Study of human H3-H4 octasome reconstitution with related chaperones in wheat germ cell-free co-expression platform
○Taiki AZUMA1, Keiichi OKIMUNE1, Junko HAGA1, Petra Banko2, Taichi TAKASUKA1,2 (1. Grad. Sch. of Global Food Resources, Hokkaido Univ., 2. Res. Fac. of Agric., Hokkaido Univ.)
[2P-094]Assessment of histone chaperone activities in H3-H4 Octasome formation in Arabidopsis thaliana
○Junko Haga1, Petra Banko2, Keiichi Okimune1, Taiki Azuma1, Taichi Takasuka1,2 (1. Grad. Sch. of GFR., Hokkaido Univ., 2. Grad. Sch. of Agr., Hokkaido Univ.)
[2P-095]Incorporation of histone H3 variant H3mm15 regulate proper gene expression during spermatogenesis
○QIANME WU1, Akihito Harada1, Kosuke Tomimatsu1, Hitoshi Kurumizaka2, Tatsuya Takemoto3, Yasuyuki Ohkawa1 (1. Div. of Transcriptomics, MIB, Kyushu Univ., 2. Laboratory of Chromatin Structure and Function, Inst. For Quantitative biosciences, University of Tokyo, 3. ab of Embryology, Inst. for Advanced Medical Sciences, Tokushima Univ.)
[2P-096]Structural and functional analysis of nucleosomes containing histone variant macroH2A
○Wenjie Xu1,2, Syota Matsumoto2, Yoshimasa Takizawa2, Mitsuo Ogasawara2, Ryo Suka1,2, Hitoshi Kurumizaka1,2 (1. Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2. Institute for Quantitative Biosciences, The University of Tokyo)
[2P-097]Possible regulation of piRNA target transposons via DNA methylation-independent mechanism
○Hiromi Yamada1, Chikara Takeuchi2, Koshi Imami1, Yuka W. Iwasaki1 (1. RIKEN IMS, 2. Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center)
[2P-098(2PS-06-08)]A functional analysis of lysine-specific demethylase KDM7A in pro-fibrotic macrophage overpolarization.
○Naofumi Funagura1,2, Tomoaki Koga1, Seonghyeon Hong1, Kan Etoh1, Ayane Noda1, Toshihiro Inoue2, Mitsuyoshi Nakao1 (1. IMEG Kumamoto Univ., 2. Kumamoto Univ.)
[2P-099]Nucleosome stability maintains cell identity and promotes healthy aging
○Hiroshi Tanaka1, Zong-Ming Chua1, Xue Lei1, Peter Adams1 (1. Sanford Burnham Prebys)
[2P-100]Analysis of UHRF1 inhibitory activity of human DPPA3 using Xenopus egg extracts
○Ayana Ota1, Atsuya Nishiyama1, Yoshie Chiba1, Shota Tanimoto2, Kyohei Arita3, Makoto Nakanishi1 (1. Dept. of Comput. Biol. and Med. Sci., Grad. Sch. of Front. Sci., Univ. of Tokyo, 2. Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo, 3. Grad. Sch. of Medical Life Science., Univ. of YCU)
[2P-101(2AS-03-04)]Stepwise establishment of facultative heterochromatin by PRC2.2 in early mouse embryos
○Masahiro Matsuwaka1,2, Mami Kumon1, Azusa Inoue1,2 (1. RIKEN IMS, 2. TMU)
[2P-102]Investigating the Impact of Transposon Insertion on Flowering Time Regulatory Genes
○SARI SAREN1, HIDETAKA ITO2 (1. Graduate School of Life Science, Hokkaido University, Sapporo, Hokkaido, Japan, 2. Faculty of Science, Hokkaido University, Sapporo Hokkaido, Japan)
[2P-103(2PS-06-06)]Unraveling the Potential Chromatin Regulatory Mechanisms of Polycomb Complexes (PcG) on Future Gene Expression Patterns.
○Mio Harachi1, Shinsuke Ito1, Takashi Kondo1, Nayuta Yakushiji1, Ryo Onishi1, Haruhiko Koseki1 (1. RIKEN IMS Genes&Dev)
[2P-104]The C-terminal region of DPPA3 is required for the inhibition of hemi-methylated DNA binding activity of UHRF1
○Shota Tanimoto1, Makoto Nakanishi1, Atsuya Nishiyama1, Yoshie Chiba1, Ayana Ota1, Kyohei Arita2 (1. Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo, 2. Grad. Sch. of Medical Life Science., Univ. of YCU)
[2P-105]Cryo-EM analysis of nucleosomes reconstituted with DNA sequences from the human genome
○Eri Ito1,2, Cheng-Han Ho1, Yuki Kobayashi1, Mitsuo Ogasawara1, Yasuyuki Ohkawa3, Yoshimasa Takizawa1, Hitoshi Kurumizaka1,2 (1. IQB, Univ. Tokyo, 2. Grad. Sch. of Sci., Univ. Tokyo, 3. MIB, Kyushu Univ.)
[2P-106(2AS-16-07)]Exploration of allele-specific DNA methylated regions in Northern pika.
○Saki Aoto1, Miyuki Shido2, Ai Yamaguchi3, Tatsuo Oshida3, Kohji Okamura4 (1. Med.Gen.Ctr., NCCHD, 2. Div. of Lab. Anim. Resour., NCCHD, 3. Lab. of Wildl. Biol., Obihiro Univ. Of Agric. and Vet. Med., 4. Dept. of Sys. BioMed., NCCHD)
[2P-107(2PS-06-02)]Epigenomic Regulation of Enhancer Regions Characterizing Breast Cancer
○Hiroaki Tachiwana1, Noriko Saitoh1 (1. The Cancer Institute of JFCR)
[2P-108]Single Molecule Imaging of Histone Tails by High-Speed Atomic Force Microscopy
○Ryota Imada1, Quynh Pham2, Yusuke Miyanari3, Shoko Sato4, Hitoshi Kurumizaka4, Mikihiro Shibata3,5 (1. Grad. Sch. Math. & Phys., Kanazawa Univ., 2. Grad. Sch. NanoLS., Kanazawa Univ., 3. WPI-NanoLSI, Kanazawa Univ., 4. Institute for Quantitative Biosciences, Tokyo Univ., 5. InFiniti, Kanazawa Univ.)
[2P-109]Binding mechanism of histone acetyltransferase p300 to the acetylated nucleosome
○Suguru Hatazawa1, Longxia Xu2, Mohamad Zandian3, Masaya Hashimoto4, Jiuyang Liu3, Genki Nakamura4, Mitsuo Ogasawara1, Gosuke Hayashi4, Yoshimasa Takizawa1, Xiaobing Shi2, Tatiana G. Kutateladze3, Hitoshi Kurumizaka1 (1. IQB, The Univ. of Tokyo, 2. Dept. of Epigenetics, Van Andel Institute, 3. Dept. of Pharmacology, Univ. of Colorado School of Medicine, 4. Dept. of Biomol. Eng., Grad. Sch. of Eng., Nagoya Univ.)
[2P-110(2PS-06-03)]How p300/CBP propagates epigenomic acetylation
○Takashi Umehara1 (1. RIKEN)
[2P-111(2AS-16-06)]Evolutionary significance of genomic imprinting in the brain revealed by the search for genomic imprinted genes in ferrets.
○Shin-ichi Horike1,4, Miyuki Shimazu1, Gensaku Okada1, Kengo Saito2, Yohei Shinmyo2,5, Koichiro Nishino3, Hiroshi Kawasaki2,4, Makiko Meguro1 (1. ReCEMHD, Kanazawa Univ., 2. Grad. Sch. of Med. Sci., Kanazawa Univ., 3. Fac. of Life Sci., Toyo Univ., 4. Sapiens Life Sci., Kanazawa Univ., 5. Hamamatsu Univ. Sch. of Med.)
[2P-112]Crosstalk among epigenetic marks for the establishment of transposon-specific silent modification in Arabidopsis
○Shoko Oda1,2, Sayaka Tominaga2, Shumpei Takeuchi1, Tetsuji Kakutani1, Taiko To1,2 (1. The University of Tokyo, 2. Institute of Science Tokyo)
[2P-113(2AS-13-02)]Loss of “chromatin regions open in random and few cells” in aged gastric stem cells and its potential impact on vulnerability to environmental stimuli
○Yuyu Liu1, Chihiro Takeuchi1, Satoshi Yamashita2, Toshikazu Ushijima1 (1. Dept. of Epigenomics, Inst. of Advanced Life Sci., Hoshi Univ., 2. Dept. of Life Engineering, Facult. of Engineering, Maebashi Inst. of Tech.)
[2P-114]Sexually dimorphic histone modification of Doublesex1 in environmental sex determination of Daphnia magna
○Nikko Adhitama1,2, Yasuhiko Kato1,2, Hajime Watanabe1,2 (1. Department of Biotechnology, Graduate School of Engineering, Osaka University, 2. Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University)
[2P-115]Construction and validation of a multicolor staining panel for detection of histone modification changes using a spectral flow cytometer.
○Rie Kamihira1, Reiko Fujii1, Fumiaki Nakamura3, Yoichi Nakao2,3 (1. Graduate School of Advanced Science & Engineering, Waseda Univ., 2. School of Advanced Science and Engineering, Waseda Univ., 3. Waseda Research Institute for Science and Engineering, Waseda Univ.)
[2P-116(2AS-13-08)]Functionality of mutant p53 in early tumorigenesis
○Tetsuya Handa1, Eleanor Sheekey1, Ioana Olan1, Masako Narita1, Masashi Narita1 (1. University of Cambridge, CRUK)
[2P-117]Single particle analysis of nucleosomes assembled by wheat germ cell-free co-expression system
○Keiichi Okimune1, Taiki Azuma1, Junko Haga1, Petra Banko2, Ryo Morishita3, Shunsuke Kita4, Katsumi Maenaka4, Taichi Takasuka1,2 (1. Hokkaido Univ. GFR, 2. Hokkaido Univ. Agr., 3. CellFree Sciences Co., 4. Hokkaido Univ. Phar.)
[2P-118]Analysis of methylation of the zebrafish hindbrain vascular mutant
○Soka Ikeda1, Misato Fujita1 (1. Kanagawa Univ.)
[2P-119]An intrinsically disordered region of histone methyltransferase Clr4/SUV39H is involved in the regulation of its enzymatic activity.
○Rinko Nakamura1,2, Yuriko Yoshimura1, Reiko Nakagawa3, Jun-ichi Nakayama1,2 (1. NIBB, 2. Sch. of Life Sci., SOKENDAI, 3. BDR, RIKEN)
[2P-120]Epigenomic regulation of oligodendrocytes by myelin constitutive protein MBP
○Kazuya Matsuo1, Urara Aoki1, Norifumi Shioda1 (1. Institute of Molecular Embryology and Genetics, Kumamoto Univ.)
[2P-121]Comprehensive analysis of histone modifications in fission yeast spores
○Aki Hayashi1, Reiko Nakagawa2, Yasuyuki Ohkawa3, Jun-ichi Nakayama1 (1. National Institute for Basic Biology, 2. Riken BDR, 3. Kyushu Univ., Medical Inst.of Bioregulation)
[2P-122]Loss-of-function of NSD2 causes abnormal placentation accompanied by fetal growth retardation in mice
○Eriko Ohnishi1, Shiori Kinoshita1, Kazuhiko Nakabayashi1, Kenichiro Hata1,2, Tomoko Kawai1 (1. Department of Maternal-Fetal Biology, National Research Institute for Child Health and Development, 2. Department of Human Molecular Genetics, Gunma University Graduate School of Medicine)
[2P-123]Functional changes of histone H3K9 methyltransferase G9a and GLP during EMT progression
○Nozomi Hamano1, Miyu Eguchi2, Haruka Kawashima3, Toshihiko Kishimoto2, Kenji Kokura2 (1. Dept.of Biomol.Sci.,Grad.Sci.,TOHO Univ, 2. Dept.of Biomol.Sci.,Facul.Sci.,TOHO Univ, 3. Dept.of Comprehensive Human Sci.,Grad.Sci.,Tsukuba Univ)
[2P-124]Functional Analysis of Histone H3-like Proteins in Paramecium
○Takayuki Kawaguchi1, Reiko Nakagawa2, Jun-ichi Nakayama1 (1. NIBB, 2. BDR, RIKEN)
[2P-125]Molecular mechanisms of transcriotional repression of malignancy-associated genes in oral cancer cell lines
○Shoichiro Tange1, Shoko Goto1, Masashi Idogawa1, Yasushi Sasaki2, Takashi Tokino1 (1. Medical Genome Sci., Sapporo Medical Univ., 2. Biology, Sapporo Medical Univ.)
[2P-126]Histone modifications in glioma cell lines
○Uugan Erdene Purevdorj1, Kimura Hiroshi1,2 (1. School of Life Science and Technology, Tokyo Institute of Technology, Yokohama 226-8501, Japan, 2. Cell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama 226-8503, Japan)
[2P-127]Analysis of changes in sperm histone modifications associated with paternal aging and neurodevelopment in the next generation
Kosuke Yamaguchi1,2, ○Joji Wada1,3, Shintaro Mise1, Yuki Okada1 (1. Laboratory of Pathology and Development, Institute for Quantitative Biosciences, The University of Tokyo. , 2. Molecular Cell Engineering Laboratory, National Institute of Genetics., 3. Graduate School of Pharmaceutical Sciences, The University of Tokyo.)
[2P-128]Novel regulatory mechanism for transcription of ribosomal protein genes in Saccharomyces cerevisiae
○Naoki Shimamura1, Tetsuro Kokubo2, Kouji Kasahara1 (1. Graduate School of Tokyo Univ of Agriculture, 2. Graduate School of Yokohama City)
[2P-129]PNUTS, a transcription terminator, represses transposable elements in the Piwi-piRNA pathway
○Yaning Wu1, Rin Imai1, Haruhiko Siomi1, Kensaku Murano1 (1. Keio University School of Medicine)
[2P-130]Identification of Heart Failure Responsive Transcription Factors Using Proximity Labeling
○Taichi Sumida1, Ken Matsuoka2, Hijiri Inoue1, Seiji Takashima1,2 (1. Graduate School of Frontier Biosciences, Osaka University, 2. Graduate School of Medicine)
[2P-131]Blood gene expression assessed in non-obese individuals confirms the link between declining insulinogenic index, inflammation and metabolic dysregulation
○Alessandro Nasti1, Miki Okumura2, Yumie Takeshita2, Tuyen Thuy Bich Ho1, Yoshio Sakai3, Taka-Aki Sato4, Chiaki Nomura2, Hisanori Goto2, Yujiro Nakano2, Takeshi Urabe5, Seiji Nakamura6, Takuro Tamura7, Kenichi Matsubara4, Toshinari Takamura2, Shuichi Kaneko1,3 (1. Information-Based Medicine Development, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., 2. Department of Endocrinology and Metabolism, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan, 3. Department of Gastroenterology, Kanazawa University Hospital, Kanazawa, Japan, 4. iLAC Co., Ltd., Tsukuba, Japan, 5. Department of Gastroenterology, Public Central Hospital of Matto Ishikawa, Hakusan, Ishikawa, Japan, 6. DNA Chip Research Inc., Tokyo, Japan, 7. Research and Development Center for Precision Medicine, University of Tsukuba, Tsukuba, Japan)
[2P-132]Molecular mechanism of activation of Y-linked genes mediated by PML body
○Saki Goto1, Shinichi Nakagawa1, Misuzu Kurihara1 (1. RNA Biology Laboratory)
[2P-133]Impact of Nuclear RNA Homeostasis on Transcriptional Condensates, Genome Structure, and Transcription
○Koichi Ogami1, Ming M Zheng2, Seiko Yoshino1, Yohei Sugimoto1, Koh Onimaru1, Phillip A Sharp3, Richard A Young2, Hiroshi I Suzuki1 (1. Grad. Sch. Med., Nagoya Univ., 2. Whitehead Inst., MIT, 3. Koch Inst., MIT)
[2P-134]DeepSpaceDB: an interactive spatial transcriptomics database that allows in-depth analysis of tissues and their substructures
○Alexis Vandenbon1, Afeefa Zainab1, Vladyslav Honcharuk1, Keiko Takemoto1, Diego Diez2, Shinpei Kawaoka3 (1. Kyoto University, 2. Osaka University, 3. Tohoku University)
[2P-135]Exploring the Regulatory Transcription Factor Network in Head and Neck Squamous Cell Carcinoma Differentiation
○Hiroaki Tawara1,2, Takaaki Tsunematsu2, Kunihiro Otsuka2, Aya Ushio3, Naozumi Ishimaru3 (1. Tokuhima Univ. Hosp., 2. Tokushima Univ., 3. Tokyo Med. Dent. Univ.)
[2P-136]CCAR1 is required for optimal transactivation function of NKX2-1
○Miyu Yoshimura1, Takumi Tanabe1, Yuto Sakurai1, Hikaru Tsutsumi1, Chisaki Nakamura1, Hanayo Watanabe1, Manaka Fujieda1, Momoka Sawada1, Ayana Ueno1, Koya Kawaguchi1, Natsumi Hasegawa1, Mitsuhiro Ito1 (1. Medical Biophysics, Kobe Univ.)
[2P-137]Nuclear receptor-binding ability of MED1 employs nuclear localization of ERα
○Ayu Muranaka1, Yuka Ohashi1, Yui Sumida1, Kyoka Imoto1, Natsuki Aoto1, Kazuki Tsutsui1, Asuka Tanaka1, Robert G Roeder2, Natsumi Hasegawa1, Mitsuhiro Ito1,2 (1. Medical Biophysics, Kobe Univ., 2. Biochem. & Mol. Biol., the Rockefeller Univ.)
[2P-138]Effect of sugar sources in the medium on polysaccharide production by Lactobacillus delbrueckii subsp. delbrueckii TUA4408L
○Kyosuke Nara1, Daigo Sakamoto2, Makoto Sugawara2, Yuh Shiwa1, Akifumi Nishida1, Nobuyuki Fujita1, Mitsuhiro Iwasaki2, Naoto Tanaka1,3 (1. Faculty of Life Sciences, Tokyo University of Agriculture, 2. MARUSAN-AI Co.,Ltd., 3. NODAI Culture Collection Center, Tokyo University of Agriculture)
[2P-139]Tracing pancreas differentiation and maturation with a multiomics approach reveals key components for functional beta cell formation.
○Ruslan Deviatiiarov1, Oleg Gusev1, Hideki Endoh1, Hiroyuki Fukuda1, Keishiro Nishimura1, Yasushi Okazaki1, Masahito Matsumoto1 (1. Juntendo University)
[2P-140]Functional analysis of Ssbp2 in odorant receptor gene expression
○Natsume Machida1, Daichi Shirakawa1, Yutaro Koide1, Yuta Kozawa1, Chizuru Kobayashi1, Toshiaki Fukushima2, Tetsuo Iwata1, Junji Hirota1 (1. Sch. of Life Sci. and Tech., Tokyo Inst. of Tech., 2. Inst of Innov Res., Tokyo Inst. of Tech.)
[2P-141]Transcriptional regulation mechanism involving cohesin loader NIPBL/MAU2
○Atsunori Yoshimura1, Rei Kajitani2, Shoin Tei1, Toyonori Sakata1, Takashi Sutani1, Takehiko Itoh2, Masashige Bando1, Katsuhiko Shirahige1 (1. IQB, The University of Tokyo, 2. School of Life Science and Technology, Tokyo Institute of Technology)
[2P-142]Development of the novel AAV vector for cardiac gene therapy with high efficacy
○Daiki Fujimori1, Matsuoka Ken2, Inoue Hijiri1, Jo Hyejin1, Takashima Seiji2,1 (1. Department of Medical Biology, Osaka University Graduate School of Frontier Biosciences, 2. Department of Medical Biology, Osaka University Graduate School of Medicine)
[2P-143]The function of Glucocorticoids in Regulating Circadian Rhythm Expression
○Shinnosuke Yanagisawa1, Yasuhiro Takenaka2, Megumi Kumagai3, Yoshihiro Nakajima4, Akira Shimada1, Masaaki Ikeda3 (1. Department of Endocrinology and Diabetes, Saitama Medical University , 2. Department of Physiology, Nippon Medical University, 3. Department of Physiology, Saitama Medical University, 4. National Institute of Advanced Industrial Science and Technology)
[2P-144]Genome and transcriptome analysis of a domestic cultivar of Japanese igusa “Suzukaze”
○Yuki Teramae1, Tomoko Kuriyama2, Masaharu Kawauchi2, Minami Matsui2, Kumiko Kihara3, Yuko Makita1,2 (1. Maebashi Inst. of Tech., 2. RIKEN CSRS, 3. NIT, Kumamoto College)
[2P-145(2PS-15-05)]Evolutionary fitness through changes in a transcriptional coactivator
○Keiichi Ito Ito1, Robert Roeder1 (1. The Rockefeller University)
[2P-146]Genome-wide measurement of transcription factor binding dynamics in human cells
○Yuko Hasegawa1, Jason D Lieb, Kevin Struhl2, John T Lis1 (1. Cornell University, 2. Harvard Medical School)
[2P-147]Regulatory mechanism for transcription of ribosomal protein genes in Candida glabrata
○Miharu Nakamura1, Naoki Shimamura1, Yuh Shiwa1, Minenosuke Matsutani2, Hiroji Chibana3, Koji Kasahara1 (1. Dept. of Mol. Microbiol., Tokyo Univ. of Agric., 2. NODAI Genome Res. Center, Tokyo Univ. of Agric., 3. Medical Mycology Research Center, Chiba University)
[2P-148]Elucidation of molecular function of FKBPs in human cells
○Yuri Ando1, Asuka Mizoguchi1, Yuh Shiwa1, Kohsuke Kataoka2, Koji Kasahara1 (1. Grad. Sch. Life Sci., Tokyo Univ. of Agric., 2. Grad. Sch. Med. Life Sci., Yokohama City Univ.)
[2P-149]Bifunctionality of DMRT1: transcriptional activation and suppression
○Naoki Ishikawa1, Daisuke Tsukamoto1,2, Takuya Matsuo1,2, Kei Tamura1,2, Michihiko Ito1,2 (1. Div. BioSci., Grad. Sch. Sci., Kitasato Univ., 2. Dept. BioSci., Sch. Sci., Kitasato Univ.)
[2P-150]Dynamics of transcription related factors in transcriptional activation
○Chihiro Takayama1, Hiroshi Kimura1,2 (1. Institute of Science Tokyo, School of Life Science and Technology, 2. Institute of Science Tokyo, Institute of Integrated Research, Cell Biology Center)
[2P-151]A competition between MITF and neural transcription factors specifies the fate of Schwann cell precursors
○Akinori Kawakami1, Miroslav Hejna2, Kenji Kabashima1, Hoang Mai3, Jun Song2, David E. Fisher4 (1. Department of Dermatology, Kyoto University Graduate School of Medicine, 2. Department of Physics, University of Illinois, 3. Department of Pathology, Massachusetts General Hospital, Harvard Medical School, 4. Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School)
[2P-152]Transcriptional dynamics in tissues of RNAP2 Ser2ph-mintbody knock-in mice
○Chihiro Matsuda1, Akane Ichiki, Yuko Sato3, Hiroshi Kimura1,2 (1. Institute of Science Tokyo・Life Science and Technology, 2. Institute of Science Tokyo・Institute of Integrated Research, 3. Kyushu University・Medical Institute of Bioregulation)
[2P-153]Chromatin dynamics in early zebrafish embryos
○Karin Fujiwara1, Hiroshi Kimura1,2, Yuko Sato3 (1. Institute of Science Tokyo・Life Sicience and Technology, 2. Institute of Science Tokyo・ Institute of Integrated Research, 3. Kyushu University・ Medical Institute of Bioregulation)
[2P-154]Development of an integrated search system for stress response genes in Arabidopsis thaliana using meta-analysis
○Yusuke Fukuda1, Kohei Kawaguchi1, Atsushi Fukushima1,2 (1. Grad. Sch. Life Env. Sci., Kyoto Pref. Univ., 2. RIKEN CSRS)
[2P-155]A study of non-coding RNA in forebrain development using single cell analysis
○Shinya Watanabe1, Miho Suzuki1, Murofushi Yoshiteru1, Keiko Shinjo1, Yutaka Kondo1 (1. Nagoya University)
[2P-156]DDX4 and HDLBP regulate progression of mouse oocyte maturation and temporal translation of Emi2 mRNA.
○Takahiro Sanada1, Tomoya Kotani1,2 (1. Biosystem Sci. Course, Grad. Sch. of Life Sci., Hokkaido Univ., 2. Dept. of Bio. Sci., Faculty of Sci., Hokkaido Univ.)
[2P-157]Analysis of SIST, a novel semi-extractable architectural RNA induced by serum starvation
○Shushi Kaneko1, Naoko Fujiwara1, Takeshi Chujo2, Chao Zeng3, Michiaki Hamada3, Tetsuro Hirose1,4 (1. 1Graduate School of Frontier Biosciences, Osaka Univ., 2. 2Graduate School of Medical sciences, Kumamoto Univ., 3. 3Research Institute for Science and Engineering, Waseda Univ., 4. OTRI, Osaka Univ.)
[2P-158]Structural and functional analysis of Retron, a prokaryotic antiphage defense system
○Kanta Yoneyama1, Junichiro Ishikawa1, Aa Haeruman Azam2, Yoshihisa Mitsuda1, Kotaro Chihara2, Sae Okazaki3, Masahiro Hiraizumi1,3, Keitaro Yamashita1,3, Kotaro Kiga2, Hiroshi Nishimasu1,3 (1. Dept. of Chem. & Biotech., Grad. Sch. of Eng., Univ. of Tokyo, 2. NIID, 3. Struct. Biol. Div., RCAST, The Univ. of Tokyo)
[2P-159(2PS-05-05)]Isotope effect on protein-RNA interactions as a risk factor for ALS
○Akira Ishiguro1, Minoru Sakama2, Takuya Saze3, Masaki Kawaguchi2, Kei-ichi Katayama4, Yoshiaki Nakayama4 (1. Hosei Univ., 2. Tokushima Univ., 3. NIFS, 4. Wakayama-Med Univ.)
[2P-160]Validation of Environmentally Derived RNA Markers for Developmental Stage Identification in Amphibians
○Tsuchida Kentaro1, Kuroda Hiroki1,2 (1. Env. Info., Keio Univ., 2. Syst. Biol., Grad. Sch. of Med. And. Gov., Keio Univ.)
[2P-161]Toward single cell fluxomics
○Satoshi Ohno1, Hideyuki Shimizu1 (1. M&D Data Science Center, Tokyo Medical and Dental Univ.)
[2P-162]Diptera-specific Daed controls Zuc endonucleolysis for piRISC production and its function
○Yuica Koga1, Shigeki Hirakata1, Mayu Negishi1, Hiroya Yamazaki1, Mikiko C. Siomi1 (1. The University of Tokyo)
[2P-163]Genome editing with Abyssicoccus albus Cas9 recognizing a unique PAM sequence and engineering the PAM sequence.
○Akiyoshi NAKAMURA1, Hiroshi YAMAMOTO1, Tsubasa YANO2, Reika HASEGAWA2, Yoichi MAKINO3, Nobutaka MITSUDA1, Teruhiko TERAKAWA2, Seiichiro ITO3, Shigeo S SUGANO1 (1. AIST・BPRI, 2. Inplanta Innovations Inc., 3. TOPPAN Inc.)
[2P-164]Mechanism of canoe mRNA localization in early Drosophila embryo.
○Ai Kawakami1, Yurou Bai1, Ryo Tanaka1, Hideki Yoshida1 (1. Dept. of Appl. Biol., Kyoto Inst. of Technol.,)
[2P-165]Kinetic analysis of archaea tRNA methyltransferase Trm56
○Soichiro Hidetaka1, Syuhei Hukumoto1, Takahiro Hasegawa1, Mami Ototake1, Shizuka Moriguchi1, Miyu Namba1, Ryota Yamagami1, Takuya Kawamura1, Akira Hirata2, Hiroyuki Hori1 (1. Graduate School of Science and Engineering, Ehime University, 2. Graduate School of Technology, Industrial and Social Science, Tokushima University)
[2P-166]The mechanism of the smallish mRNA localization in the early Drosophila embryos
○Hiroto Yoshida1, Hideki Yoshida1 (1. Dept. of Appl. Biol., Kyoto Inst. of Technol.)
[2P-167]ADAR1 p110 and Its Role in Double-Stranded RNA Modulation
○Yu Gao1, Yuke Wu1, Taisuke Nakahama1, Yukio Kawahara1 (1. Osaka University)
[2P-168]Novel microRNA expression vector overcoming disadvantages of two types of commercially available vectors
○Kenichiro Yamada1, Daisuke Fukushi1, Yasuyo Suzuki1, Noriko Nomura1, Shin Hayashi1 (1. Institute for Developmental Research, Aichi Developmental Disability Center)
[2P-169]Elucidation of the role of the N-terminal prion-like domain of SGS3 in plant secondary siRNA biogenesis
○Yuji Fujimoto1, Yuriki Sakurai1, Keisuke Shoji2, Manabu Yoshikawa3, Hiro-oki Iwakawa1 (1. Rikkyo University, 2. Tokyo University of Agriculture and Technology, 3. NARO)
[2P-170]Development of an aptazyme that feedback-regulates the expression of human AML1 protein
○Tetsumichi Yokota1, Hiro Yoshida1, Yoichiro Tanaka2, Tomoko Kozu3, Taiichi Sakamoto1 (1. Chiba Institute of Technology, 2. Yokohama National University, 3. Saitama Cancer Center)
[2P-171]Biochemical analysis of conformational change and translation control mechanism by the translational riboswitch
○Yuki Tanaka1, Hiroyuki Hamada2, Shunsuke Matsumoto2, Tomoyuki Numata2 (1. Grad. Sch. Bioresource and Bioenviron. Sci., Kyushu Univ., 2. Grad. Sch. Bioresource and Bioenviron. Sci., Kyushu Univ.)
[2P-172]Uncovering the pathogenic mechanism underlying Aicardi-Goutières syndrome-like encephalopathy caused by mutations in the RNA-editing enzyme ADAR1
○Hyebin Yoo1, Reiichi Sugihara2, Taisuke Nakahama1,2,3,4, Yuki Kato1,2,3, Yukio Kawahara1,2,3,4,5 (1. Department of RNA Biology and Neuroscience, Graduate School of Frontier Biosciences, Osaka University, 2. Department of RNA Biology and Neuroscience, Graduate School of Medicine, Osaka University, 3. Integrated Frontier Research for Medical Science Division and RNA Frontier Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University, 4. Center for Infectious Disease Education and Research (CiDER), Osaka University, 5. Genome Editing Research and Development Center, Graduate School of Medicine, Osaka University)
[2P-173]The therapeutic effects of chemically-modified microRNA-140 in Osteoarthritis
○Reiji Hirai1, Maho Hashimoto1, Manami Matsufusa1, Masayuki Takeda1, Yutaro Uchida1, Tomoki Chiba1, Hiroshi Asahara1 (1. Institute of Science Tokyo)
[2P-174(2MS-08-04)]Interaction between CDK12 and NXF1 in DNA damage response
○Shunsuke Ebara1,2, Misaki Yoshida1, Hiroko Yamakawa1,2, Keichiro Shimokawa1, Hiroshi Tauchi2, Daisuke Morishita1 (1. Chordia Therapeutics Inc., 2. Ibaraki University)
[2P-175]CRISPR-Cas12a activity depends on the conditions for ribonucleoprotein complex formation
○Mai Yamasaki1, Yusuke Kamachi1 (1. Kochi University of Technology)
[2P-176]Expression and functional analysis of lncRNA BC006965 in cartilage
○Naoto Ouchi1, Ayana Suzuki1, Masafumi Inui1 (1. Laboratory of Animal Regeneration systemology, Department of Life Sciences, School of Agriculture, Meiji University)
[2P-177]The processing of clustered H/ACA box snoRNAs mediated by a Zc3h12 family protein in Drosophila
○Mitsunaga Hamashima1, Tomohiro Yamano1, Shigeki Hirakata1, Mikiko C. Siomi1 (1. Dept. of Biol. Sci., Grad. Sch. of Sci., The University of Tokyo)
[2P-178]Regulation of miRNA expression by splicing factor HNRNPA1
○Masataka Yuri1, Yuma Hanai1, Katsutomo Okamura1 (1. NAIST, Biological Science)
[2P-179]Role of Nanos protein in the P-body-like germ granules in Drosophila embryogenesis
○Yasuhiro Kozono1, Miho Asaoka2, Makoto Hayashi3, Satoru Kobayashi2 (1. Deg. Prog. in Life and Earth Sci., Grad. Sch. of Sci. and Tech., Univ. of Tsukuba, 2. Life Science Center for Survival Dynamics, Univ. of Tsukuba, 3. Inst. Aqua. Biotech., Tokyo Univ. of Marine Sci. and Tech.)
[2P-180]Simulation-based parameter that can accurately estimate the extent of attenuation of siRNA off-target effect by structural distortions caused by chemical modifications
○Seongjin An1, Yoshiaki Kobayashi2, Kohei Nomura3, Yasuaki Kimura3, Hiroshi Abe3, Kumiko Ui-Tei1,2 (1. Graduate School of Frontier Sciences, The University of Tokyo, 2. Graduate School of Science, The University of Tokyo, 3. Graduate School of Science, Nagoya University)
[2P-181]TRA2B promotes colon cancer progression via biogenesis of onco-microRNAs
○Yuki Kuwano1, KEYOUMU NAZERE1, Nanako Oohama2, Souru Taniguchi2, Kensei Nishida3, Masaki Kamada1, Hiroyuki Morino1 (1. Tokushima Univ. Medical Genetics, 2. Tokushima Univ., 3. Tokushima Univ. Medical Education)
[2P-182]Interaction between Dicer and viruses in the tick small RNA pathway
○Maho Iwata1, Masami Shiimori1, Junko Iida1, Katsutomo Okamura1 (1. Nara Institute of Science and Technology)
[2P-183]Effects of ethanol and temperature on translation activity and Ded1 aggregation in yeast
○Yutaka Fuanahashi1, Shingo Izawa1 (1. Kyoto Institute of Technology)
[2P-184]Formation of the nuclear granules of proteasome components under acetic acid stress
○Mitsuki Imajo1, Vo Thi Anh Nguyet1, Shingo Izawa1 (1. Kyoto Institute of Technology)
[2P-185(2PS-15-09)]Regulation of translation speed by RPL41 contributes to the production of long proteins
○Mina Hirata1, Kazuya Ichihara1, Keiichi Nakayama2, Akinobu Matsumoto1 (1. Nagoya University, 2. TMDU)
[2P-186(2AS-04-04)]tRNA modifications orchestrate the translational response to mitochondrial stress.
○Sherif Rashad1, Shadi Al-Mesitef1, Abdulrahman Mousa1, Yuan Zhou1, Daisuke Ando1, Guangxin Sun3, Tomoko Fukuuchi2, Yuko Iwasaki1, Jingdong Xiang3, Shane R Byrne3, Jingjing Sun3, Masamitsu Maekawa1, Daisuke Saigusa2, Thomas J Begley4, Peter C Dedon3, Kuniyasu Niizuma1 (1. Tohoku University, 2. Teikyo University, 3. Massachusetts Institute of Technology, 4. University at Albany, NY, USA)
[2P-187]Ribosomal protein eS7A monoubiquitination is crucial for translational regulation of HAC1i mRNA
○Nichika Sato1, Yu Nakano2, Yasuko Matsuki2, Yoshitaka Matsuo1, Tohru Yoshihisa3, Toshifumi Inada1 (1. The University of Tokyo, 2. Tohoku University, 3. University of Hyogo)
[2P-188(2PS-07-07)]IbpA, an Escherichia coli small Hsp, is an aggregation-sensor that regulates its own translation and heat shock response at a translational level.
○Tsukumi Miwa1, Hideki Taguchi1 (1. Tokyo Tech. IIR. CBC)
[2P-189]Translation inhibition by intron sequence of human CDK5RAP2 gene.
○Yuka Araki1, Kensuke Hayashi1 (1. Sophia Univ.)
[2P-190]Comprehensive analysis of ribosome stalling sites in plants
○Ryosuke Kowada1,2,3, Shintaro Iwasaki4, Yukihide Tomari1,2, Hiro-oki Iwakawa3 (1. Dept. of C. Biol. and Med. Sci., Grad. Sch. of Front. Sci., Univ. of Tokyo, 2. Inst. Of Quant. Biosci., Univ. of Tokyo, 3. Dept. of Life Sci., College of Sci., Rikkyo Univ., 4. RIKEN CPR)
[2P-191(2AS-04-03)]Cellular stress from tRNALeuCAA intron deletion in budding yeasts
○Sachiko Hayashi1, Ryujiro Nakamura2, Soujirou Ukeda2, Hitomi Kato2, Tohru Yoshihisa1 (1. Grad. Sch. Sci., Univ. Hyogo , 2. Facul. Sci., Univ. Hyogo)
[2P-192(2PS-05-07)]Molecular mechanism of NOP56 GGCCUG Repeat Associated Non-AUG (RAN) translation
○Mayuka Hasumi1, Hayato Ito1, Kodai Machida2, Tatsuya Niwa1,3, Tomoya Taminato4, Yoshitaka Nagai4, Hiroaki Imataka2, Hideki Taguchi1,3 (1. Science Tokyo, Sch. Life Sci. Tech., , 2. Univ. of Hyogo, Dept. of Eng., 3. Science Tokyo, IIR, 4. Kindai univ., Med.)
[2P-193]The comprehensive analysis of nonsense-mediated mRNA decay caused by frameshift mutations in Arabidopsis thaliana
○Hiroto Michishita1, Tomoko Kuriyama2, Masaharu Kawauchi2, Minami Matsui2, Yuko Makita1,2, Yukio Kurihara2 (1. Maebashi Tech, 2. RIKEN SCRS)
[2P-194]Analysis of the effects of N-terminal proteoforms on NIPA1 function
○Risa Ikarashi1, Atsushi Hatano1, Masaki Matsumoto1 (1. Niigata University Graduate School)
[2P-195(2PS-07-08)]Surveying tRNA modifications to unveil translation regulation underpinning bacterial pathogenesis
○Satoshi Kimura1 (1. Cornell University)
[2P-196]Elucidating the intracellular functions of translation initiation factor 2 (IF2) in E. coli.
○Misaki Ishigooka1, Tatsuya Niwa1,2, Yuhei Chadani3, Hideki Taguchi1,2 (1. Sch. Life Sci. Tech., Science Tokyo, 2. IIR, Science Tokyo, 3. Dept. of Biol., Fac. of Sci., Okayama Univ.)
[2P-197(2PS-07-05)]The mechanism of translation termination inhibition by a ribosome arrest peptide PepNL
○Yushin Ando1, Yuzuru Itoh1, Akinao Kobo2, Yuhei Chadani3, Hideki Taguchi2,4, Osamu Nureki1 (1. Grad. Sch. of Sci., Univ. of Tokyo, 2. Dept. of Life Sci. & Tech, 3. Dept. of Biol. Fac. of Sci., Okayama Univ, 4. Cell Biol. Ctr., IIR, Tokyo Tech)
[2P-198]Analysis of the translational GTPase GTPBP1 in zebrafish
○Miku Kadota1, Yuichiro Mishima1 (1. Kyoto Sangyo Univ.)
[2P-199]The cellular localization of EEF1D isoforms is regulated by alternative splicing
○Mohamad Jamous1, Masaki Hosogane1, Xiaoxin Huang2, Atsushi Hatano3, Masaki Matsumoto3, Keiko Nakayama1 (1. Division of Cell Proliferation, Graduate School of Medicine, Tohoku University. , 2. Graduate School of Life Sciences, Tohoku University., 3. Department of Omics and Systems Biology, Niigata University.)
[2P-200]G-Quadruplex structures in AR mRNA negatively regulate its translation
○Seiya Takemoto1, Masataka Nakano1,2, Tatsuki Fukami1,2, Miki Nakajima1,2 (1. Faculty of Pharmaceutical Sciences, Kanazawa University, 2. WPI Nano Life Science Institute (WPI-NanoLSI), Kanazawa University)
[2P-201]Effects of mRNA cap structures and a poly(A) sequence
on translation efficiency in early zebrafish embryos
○Takanori Hamamoto1, Yusuke Kamachi1 (1. Kochi University of Technology)
[2P-202]Exploration of optimal conditions for the incorporation of noncanonical amino acids by amber suppression using the PURE system
○Rena Matsumoto1, Takayoshi Watanabe2, Takahiro Hohsaka2, Takashi Kanamori1 (1. GeneFrontier Corporation, 2. School of Materials Science, Japan Advanced Institute of Science and Technology (JAIST))
[2P-203]In vitro selection of nonnatural cyclic peptides through multiple stop codon reassignment
○Takayoshi Watanabe1, Takahiro Hohsaka1 (1. School of Materials Sci., JAIST)
[2P-204]The N-terminal helix of Gα protein rotates to promote Gα activation
○Hiroki Arai1, Tatsuya Ikuta1, Manae Tatsumi1, Roji Kise1, Daisuke Sasaki2, Wataru Shihoya3, Osamu Nureki3, Kazuhiro Mio4, Yuji Sasaki2, Asuka Inoue1,5 (1. Grad Sch of Pharm Sci, Tohoku Univ, 2. Grad Sch of Frontier Sci, Univ of Tokyo, 3. Grad Sch of Sci, Univ of Tokyo, 4. AIST-UTokyo OPERANDO-OIL, 5. Grad Sch of Pharm Sci, Kyoto Univ)
[2P-205]The theory and practice of a small molecule inhibitor design focusing the high free energy state of its target kinase
○Sora Suzuki1, Koji Umezawa2, Gaku Furuie1, Daichi Nakamura3, Ninako Kimura1, Masato Yamakawa1, Yuto Sumida3,4, Takashi Niwa3,4,5, Takamitsu Hosoya3,4, Isao Kii1,2 (1. Department of Agriculture, Graduate School of Science and Technology, Shinshu University, 2. Institute for Biomedical Sciences, Shinshu University, 3. Laboratory for Chemical Biology, RIKEN BDR, 4. Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 5. Graduate School of Pharmaceutical Sciences, Kyusyu University)
[2P-206]Analysis of the bundling of F-actins by α-actinin and SYNPO2La
using high-speed AFM
○Hirona Osaka1, Eizo Takashima2, Hiroshi Yamada3, Kohji Takei3, Takayuki Uchihashi1,4 (1. Nagoya university , 2. Ehime university, 3. Okayama university, 4. ExCELLS)
[2P-207]Development of the "AlissAID" system degrade target protein using single domain antibodies.
○Yoshitaka Ogawa Ogawa1, Kohei Nishimura1, Keisuke Obara1, Takumi Kamura1 (1. Nagoya univ.)
[2P-208]Client recognition differences between PDI and ERp46 to guide oxidative folding
○Kotone Ishii1,2, Shingo Kanemura1, Hiroyuki Kumeta3, Motonori Matsusaki4, Tomohide Saio4, Masaki Okumura1 (1. FRIS, Tohoku Univ., 2. Grad. Sch. of Life Sci., Tohoku Univ., 3. Fac. of Adv. Life Sci., Hokkaido Univ., 4. Inst. of Adv. Med. Sci., Tokushima Univ.)
[2P-209]Understanding the liquid-solid phase transition from protein quality control granule to stress granule
○Mai Watabe1,2, Shingo Kanemura2, Kotono Suzuki1,2, Kazunori Ban3, Shinichi Sato2, Motonori Matsusaki4, Kenji Inaba5, Takakazu Nakabayashi3, Young-Ho Lee6, Tomohide Saio4, Masaki Okumura1,2 (1. Grad. Sch. of Life Sci., Tohoku Univ., 2. FRIS, Tohoku Univ., 3. Grad. Sch. of Pharm. Sci., Tohoku Univ., 4. IAMS, Tokushima Univ., 5. MIB, Kyushu Univ., 6. KBSI, South Korea)
[2P-210]Analysis of the aggregation mechanism of ubiquitinated CPEB3, a long-term memory-related protein
○Harunobu Saito1, Motoharu Ueno2, Daichi Morimoto3, Naotaka Sekiyama2, Masatomo So1, Ayako Furukawa1, Kenji Sugase1 (1. Graduate School of Agriculture, Kyoto Univ., 2. Graduate School of Science, Kyoto Univ., 3. Graduate School of Engineering, Kyoto Univ.)
[2P-211]Functional and structural effects of CMT1-related amino acid substitutions on the extracellular domain of myelin protein zero
○Emika Neriki1, Kotaro Okamura2, Mikio Tanabe3, Kazuhiro Mio2,4, Masayoshi Sakakura1,2 (1. School of Sci, Yokohama City Univ., 2. Grad School of Med Life Sci, Yokohama City Univ., 3. KEK, IMSS, SBRC, 4. AIST-UTokyo operando OIL)
[2P-212]Bioplastic (PHB) production at high temperatures using high temperature-adapted evolved E.coli
○Waka Makino1, Miwa Kimura1, Noriko Kobayashi1, Toshihiko Kishimoto1, Kenichiro Matsumoto2 (1. Toho Univ., 2. Hokkaido Univ.)
[2P-213]Structural analysis for substrate recognition mechanisms of human FAD synthase FLAD1
○Sayaka Hokazono1, Manabu Igarashi2, Yusuke Satoh3, Masahiro Sonoshita3, Takahisa Ikegami1, Tsuyoshi Konuma1 (1. Graduate School of Medical Life Science, Yokohama City University, 2. Hokkaido University International Institute for Zoonosis Control, 3. Institute for Genetic Medicine, Hokkaido University)
[2P-214]Recognition mechanism of defective prions by the neuron specific chaperon GDI1
○TOMOKI ONODERA1 (1. TOKYO METROPOLITAN UNIVERSITY)
[2P-215]Prediction of Metal Ion-Protein Binding Using Graph Neural Network
○Yamato Maehara1, Masafumi Shionyu1 (1. Grad. sch. Biosci., Nagahama Inst. Bio-Sci. Tech.)
[2P-216]Crystal Structure of the rice blast fungus copper transporter MoICT1
○So Tanaka1, Yuta Iguchi1, Toshiki Komano1, Kota Hibino1, Ryo Uehara1, Tetsuro Okuno2, Hiroyoshi Matsumura1, Atsushi Takeda1 (1. Dept. of Life Sci., Grad. Sch. of Life Sci., Ritsumeikan Univ., 2. Ritsumeikan Univ.)
[2P-217]Tracing the History of Fold-Metabolism Coevolution
○Tatsuya Corlett1, Harrison B. Smith1,2, Joshua E. Goldford2,3,4, Liam M. Longo1,2 (1. Earth-Life Science Institute, Tokyo Institute of Technology, Tokyo, Japan., 2. Blue Marble Space Institute of Science, Seattle, WA, USA., 3. Division of Geological and Planetary Sciences, California Institute of Technology, Pasadena, CA, USA., 4. Physics of Living Systems, Massachusetts Institute of Technology, Cambridge, MA, USA.)
[2P-218]Dynamic movement of recombinant FGFR 1 observed at one molecule level by High Speed-Atomic Force Microscope (HS-AFM)
○Yuma Myokan1, Saren qiqige1, Tsunaki Hongu1,4, Katsuya Sakai2,3, Neval Yilmaz2,3, Kunio Matsumoto2,3, Mikihiro Shibata3,5, Noriko Gotoh1,4 (1. Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, 2. Division of Tumor Dynamics and Regulations, Cancer Research Institute, Kanazawa University, 3. WPI-Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, 4. Innovative Cancer Model Research Unit, Institute for Frontier Science Initiative, Kanazawa University, 5. High-speed AFM for Biological Application Unit, Institute for Frontier Science Initiative, Kanazawa University)
[2P-219]Development of protein half-life prediction model for large-scale analysis of protein lifetime.
○Tatsuya Sagawa1,2, Eisuke Kanao1,2, Kosuke Ogata1, Yasushi Ishihama1,2 (1. Grad. Sch. Pharm. Sci., Kyoto Univ., 2. NIBIOHN)
[2P-220]Observation of sodium ion allosteric effects on opioid receptors
○Ryo Nishikawa1, Seiya Iwata1, Ryoji Suno2, Chiyo Suno-Ikeda2, Takuya Kobayashi2, Kota Katayama1,3, Hideki Kandori1,3 (1. Grad. Sch. Eng., Nagoya Inst. Tech., 2. Dept. of Med., Kansai Med. Univ., 3. OptoBioTech. Res. Ctr., Nagoya Inst. Tech.)
[2P-221]Prior evaluation of egg bioreactorization using cultured cells
○Ryo Ikegaya1, Tenkai Watanabe1, Takumi Terada1, Ryo Ezaki1, Mei Matsuzaki1, Hiroyuki Horiuchi1,2 (1. Grad. Sch. Int. Sci. Life, Hiroshima Univ. , 2. Genome Edit. Innov. Ctr, Hiroshima Univ.)
[2P-222]Why can GFP which has lost its fluorescence be massively expressed?
○Yuri Fujita1, Hisao Moriya1 (1. Okayama Univ.)
[2P-223]Development of synthesis and ligand response methods for mammalian odorant receptors using cell-free protein synthesis
○Yutaka Kuwamura1, Ikumi Takayama2, Masafumi Yohda1,2, Yosuke Fukutani1,2 (1. Dept. of Biotechnol. Tokyo Univ. of Agric. and Technol., 2. Dept. of Biotechnol. Tokyo Univ. of Agric. and Technol.,)
[2P-224]Understanding the recognition mechanism of misfolded TDP-43 by LONRF2
○Taiki Kobayashi1, Kyohei Arita2, Makoto Nakanishi3 (1. Yokohama City Univ., 2. Yokohama City Univ., 3. Tokyo Univ.)
[2P-225]Exploration of the D-Aspartate Biosynthetic Pathway in Mammals
○Miyabi Hasegawa1, Yui Takahashi1, Kouichi Kurose1, Hiroki Koyama1 (1. Tokyo University of Marine Science and Technology)
[2P-226]The role of transposon-related CRISPR-Cas effector in R-loop formation
○Kazuki Ishihara1, Shunsuke Matsumoto1, Tomoyuki Numata1 (1. Kyushu University)
[2P-227]Reversible reaction mechanism analysis of the citrate synthase from thermophilic bacterium Desulfurella acetivorans
○Akihiro Onishi1, Yoshiaki Nishiya1 (1. Div. of Life Sci., Grad. Sch. of Sci. and Eng., Setsunan Univ.)
[2P-228]Molecular dynamics simulation of biomolecule adsorption on crystalline cellulose films.
○Kouichirou Ishibashi1, Sawa Ishii1, Hiromi Tsuyuki1, Takeshi Serizawa2, Yoshiki Ishii3, Go Watanabe1,3,4 (1. Grad. Sch. of Sci., Kitasato Univ., 2. Sch. of Mater. and Chem. Tech., Tokyo Inst. of Tech., 3. Sch. of Front. Eng., Kitasato Univ., 4. KISTEC)
[2P-229]Structural snapshots reveal mechanisms of target DNA cleavage by a thermostable Cas9
○Osamu Kikko1, Shunsuke Matsumoto1, Sonoko Ishino1, Hiroyuki Matsumoto2, Masahiro Noguchi2, Tomoyuki Numata1, Yoshizumi Ishino1 (1. Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, 2. Takara Bio Inc.)
[2P-230]Functional analysis of the linker between the IBB domain and ARM repeat of importin α, a intrinsically disordered region.
○Hinata Sugasawa1, Noriko Yasuhara2, Onda Yoshiaki1 (1. Nihon Univ., 2. Nihon Univ. Bioscience)
[2P-231]Oligomerization and interaction mechanism of the innate immune signaling protein MyD88 studied by solution NMR
○Shiho Nukui1, Yudai Ito1, Kazuki Kasai1, Hidehito Tochio1 (1. Kyoto University)
[2P-232]High-Speed Atomic Force Microscopy Reveals Structural Dynamics of Microtubule-Associated Protein Tau Aggregation.
○Tatsuya Kimura1, Kenjiro Ono2, Ken-ichi Umeda1, Daiki Muramatsu2, Hiroki Konno1, Noriyuki Kodera1, Toshio Ando1, Takahiro Nakayama1 (1. WPI-Nano Life Science Institute, Kanazawa Univ. , 2. Department of Neurology Kanazawa University Graduate School of Medical Sciences)
[2P-233]Design of proteins that undergo liquid-liquid phase separation and their sequence-dependent properties
○Haru Takabatake1, Yumiko Ohhashi2, Hideki Taguchi1,2 (1. Sch. Life Sci. Tech., Science Tokyo, 2. IIR, Science Tokyo)
[2P-234]Analysis of the Centromere Localization Mechanism of SET Protein and the Regulation Mechanism of Chromosome Alignment during Mitotic Phase
○Marina Awaji1, Yuichiro Asai1, Junji Seino1,2, Yasuhiko Terada1 (1. Dept. of Chem. and Biochem., Grad. Sch. of Adv. Sci. and Eng., Waseda Univ., 2. Waseda Res. Inst. for Sci. and Eng.)
[2P-235]Structure and function analysis of dienelactone hydrolase (DLH) from hyperthermophilic bacterium Aquifex aeolicus
○Sayo Dairiki1, Sho Ito1, Tatsuya Nishino1 (1. Tokyo University of Science)
[2P-236]Development of a α-ketobutyrate-specific enzyme by structure-based alteration of lactate dehydrogenase
○Momoka Nakamura1, Yoshiaki Nishiya1 (1. Div. of Life Sci., Grad. Sch. of Sci. and Eng., Setsunan Univ.)
[2P-237]Purification of Mammalian V-ATPase and Determination of Inhibitor Binding Structure
○Yui Nishida1, Atsuko Nakanishi2, Atsuki Nakano1, Fuka Ueda1, kaoru Mitsuoka2, Ken Yokoyama1 (1. Kyoto Sangyo Univ., 2. Research Center for UHVEM., Osaka Univ.)
[2P-239]Functional interactions between ERp57 and other PDI family members to guide protein folding
○Airu Takeuchi1,2, Motonori Matsusaki3, Tomohide Saio3, Kenji Inaba4, Shingo Kanemura1, Masaki Okumura1,2 (1. FRIS, Tohoku Univ., 2. Grad. Sch. Of Life Sci., Tohoku Univ., 3. IAMS, Tokushima Univ., 4. MIB, Kyushu Univ.)
[2P-240]Analysis of Myo1D and Myo1C involved in left-right asymmetry in Drosophila
○Suguru Sato1, Kohei Yoshimura1, Takeshi Haraguchi2, Asuka Yamaguchi3, Kenji Matsuno3, Kohji Ito2 (1. Grad. Sch. Sci., Univ. Chiba, 2. Sch. Sci., Univ.Chiba, 3. Grad. Sch. Sci., Univ. Osaka)
[2P-241]Further developments of the minimal luciferase picALuc: luminescence intensity and duration
○Yuki Ohmuro-Matsuyama1, Yae Touda1, Tadaomi Furuta2 (1. Shimadzu Corporation, 2. Tokyo Institute of Technology)
[2P-243]The Computational Study on the Secondary Structure Formation of Nascent Peptides Inside the Ribosome Tunnel with Biomolecular Environments Mimicking Models.
○Takunori Yasuda1, rikuri morita2, yasuteru shigeta2, ryuhei harada2 (1. Doctral Program in biology, University of Tsukuba, 2. Center for Computational Sciences, University of Tsukuba)
[2P-244]Establishment of purification system for FtsH monomer
○Toyoki Amano1, Sora Akezaki1 (1. Dept. Bioscience, Fac. Sci., Shizuoka Univ.)
[2P-245]Phase separation of ALS-associated FUS mutants under oxidizing conditions
○Takanari Tanimoto1, Takuya Yoshizawa1, Naoya Sasahara1, Ryo Uehara1, Hiroyoshi Matsumura1 (1. Dept. of Life Sci., Grad. Sch. of Life Sci., Univ. of Ritsumeikan)
[2P-246]mRNA display selection of intrabodies binding to the AXL intracellular domain
○Kotone Jike1, Taihei Nagafuchi1, Kei Fujiwara1, Hitoshi Tsugawa2, Nobuhide Doi1 (1. Grad. Sch. Sci. & Tech., Keio Univ., 2. Tokai Univ. Sch. Med.)
[2P-247]Comparative analysis of structural and thermal stability of a proton- pumping rhodopsin RxR in different membrane mimetic environments
○Chihiro Kikuma1, Rika Suzuki1, Yuji Tokunaga2, Koh Takeuchi2, Keiichi Kojima3, Yuki Sudo3, Hideo Takahashi1 (1. Grad. Sch. of Med. Life Sci., YCU, 2. Grad. Sch. of Pharma. Sci., Univ. of Tokyo, 3. Grad. Sch. of Med., Dent. and Pharma. Sci., Univ. of Okayama)
[2P-248]Ten Years of jPOST: Toward the future of an integrated database for proteomics
○Akiyasu C. Yoshizawa1, Yushi Takahashi1, Daiki Kobayashi1, Yuki Moriya2, Atsushi Hatano1, Tomoyo Takami1, Masaki Matsumoto1, Norie Araki3, Tsuyoshi Tabata4,5, Mio Iwasaki5, Naoyuki Sugiyama6, Yoshio Kodera7, Atsushi Fukushima8, Satoshi Tanaka9, Susumu Goto2, Shin Kawano2,7, Shujiro Okuda1, Yasushi Ishihama5 (1. Niigata Univ., 2. DBCLS, DS, ROIS, 3. Kumamoto Univ., 4. MassSoft, 5. Kyoto Univ., 6. Nat. Cerebral and Cv. Ctr., 7. Kitasato Univ., 8. Kyoto Pref. Univ., 9. Trans-IT)
[2P-249]Construction of a classifier for carbohydrate-related enzyme sequences based on their substrate specificity.
○Masahiro Otao1, Toshio Ariyasu1, Shuichi Hirose1 (1. Nagase Viita Co., Ltd.)
[2P-250]Development of a method for exploring drug target proteins using proximity biotinylation
○Norito Katsuo1, Satoshi Sakamoto1, Yuki Yamaguchi1 (1. Dept. of Life Science and Technology, Institute of Science Tokyo)
[2P-251]Functional analysis of Glucose-6-Phosphate Dehydrogenase from Myxococcus xanthus
○Yuki Ueno1, Yoshio Kimura1 (1. Kagawa University)
[2P-252]Discrimination prediction of condensates formed
by liquid-liquid phase separation
○Ami Matoba1 (1. Kwansei Gakuin University)
[2P-253]Analysis of the role of the molecular chaperone Hsp104 in disaggregation of amyloid fibril
○Moeka Hayata1, Kentaro Noi2, Masahumi Yohda1, Kyosuke Shinohara1 (1. Tokyo University of Agriculture and Technology, 2. Kobe University)
[2P-254]Molecular and Cell Engineering for the Production of Bispecific Antibodies
○Masayoshi Onitsuka1, Yamato Okita2, Noa Bando2, Miku Yamasaki3 (1. Grad. Sch. Tech. Ind. Soc. Sci., Tokushima Univ., 2. Grad. Sch. Sci. Tech., Tokushima Univ., 3. Fac. Biosci. Bioind., Tokushima Univ.)
[2P-255]Enzymatic characterization of inorganic pyrophosphatase in the mucus bacterium Myxococcus xanthus.
○Sunao Ueda1, Yoshio Kimura1 (1. Kagawa University)
[2P-256]Development of a non-invasive species identification method using spider silk proteomics
○Phillip Keigo Yamamoto1,2, Keizo Takasuka1,2,3, Masaru Mori1,2,4, Takeshi Masuda1,2, Nobuaki Kono1,2,5 (1. Inst. Adv. Biosci., Keio Univ., 2. Syst. Biol. Prog. Grad. Sch. Media & Governance, Keio Univ., 3. Dept. Biol., Grad. Sch. Sci., Kyushu Univ., 4. Current Address: Inst. Innovation for Future Society, Nagoya Univ., 5. Environment & Info. Studies, Keio Univ.)
[2P-257]DEAD box RNA helicase5(DDX5/p68) binds directly to E2F1
○Naoyasu Nishimura1, Kiyoshi Ohtani1, Tomoko Warita1 (1. KWANSEI GAKUIN UNIVERSITY)
[2P-258]Structural analysis of the complexes between sarcosine oxidase and 5-membered cyclic imino acids
○Yuqi Zhang1, Yoshitaka Nakajima1, Misae Kurobe1, Tsutomu Nakamura2, Tomoki Himiyama2, Yoshiaki Nishiya1 (1. Div. of Life Sci., Grad. Sch. of Sci. and Eng., Setsunan Univ., 2. Natl. Inst. Adv. Ind. Sci. Technol. (AIST))
[2P-259]Single molecule imaging of mitochondrial outer membrane fusion regulators Mfn1 and Mfn2
○Shiho Kawai1, Shintaro Kita1, Noriyuki Kodera2, Yuhei Araiso1 (1. Div. of Health Sci., Kanazawa Univ., 2. NanoLSI, Kanazawa Univ.)
[2P-260]Development of a mass spectrometry-based single-cell multi-omics analysis
○Kosuke Hata1, Asako Sawano2, Masatomo Takahashi1, Mamoru Hirafuji3, Masaki Matsumoto4, Takeshi Bamba1, Atsushi Miyawaki2,5, Yoshihiro Izumi1 (1. Medical Institute of Bioregulation, Kyushu University, 2. RIKEN Center for Brain Science, 3. YODAKA Co., Ltd, 4. Graduate School of Medical and Dental Sciences, Niigata University, 5. RIKEN Center for Advanced Photonics)
[2P-261]Mass production of active BmPP using silkworm-baculovirus expression system and its potential application to cell culture
○Masahiro Saiki1, Masato Hino2, Akitsu Masuda2, Tsuguru Fuji2, Hiroaki Mom2, Takahiro Kusakabe2, Jaeman Lee2 (1. Kyushu Univ. graduated school, 2. Kyushu Univ.)
[2P-262]Synechocystis sp. PCC 6803 accumulate citrate in the cell due to the regulation of isocitrate dehydrogenase
○Honoka Suzuki1, Masahiro Karikomi2, Kanako Iseki1, Takashi Osanai2 (1. Meiji University, 2. Meiji University Graduate School)
[2P-263]Multiple evolutionary paths toward C20 minicarotenoid biosynthetic enzymes
○Yui Araki1, Takumi Ojima2, Daisuke Umeno1 (1. Department of Applied Chemistry, Waseda University, 2. Department of Applied Chemistry and Biotechnology, Chiba University, Japan)
[2P-264]Establishment of a platform for the development of novel xCT inhibitors
○Ryosuke Zaitsu1,3, Yuto Ohno2, Fumiya K Sano1, Tatsuki Tanaka1, Takaaki A Kobayashi1, Yoshiaki Kise1, Tsukasa Kusakizako1, Haruo Aikawa2, Naohiro Terasaka2, Kazumasa Oda1, Shojiro Kitajima3, Hiroaki Suga2, Osamu Nureki1 (1. Department of Biological Sciences,Graduate School of Science, The University of Tokyo, 2. Department of Chemistry, Graduate School of Science, The University of Tokyo, 3. Institute for Advanced Biosciences, Keio University)
[2P-265]Directed evolution of CO2 fixation enzyme using cell free expression biosensor and droplet sorting
○Shohei Ito1, Naohiro Terasaka2, Shota Nishikawa2, Kosuke Fujishima2 (1. Tokyo Tech. LST., 2. Tokyo Tech. ELSI.)
[2P-266]Dynamicity of chromatin-associated tardigrade-unique DNA protection protein Dsup in living cells
○Kota Shinzaki1, Takekazu Kunieda1 (1. (1.Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo)
[2P-267]Hiv-1 Gag dimerization is affected by the mobility around S9 residues
○Keisuke Kamba1, Taiki Morita1,2, Osamu Kotani3, Takaaki Koma4, Masaru Yokoyama3, Masako Nomaguchi4, Hironori Sato3, Takashi Nagata1,2, Katahira Masato1,2 (1. Inst. Adv. Energy, Kyoto Univ., 2. Grad. Sch. Energy. Sci., Kyoto Univ., 3. Pathog. Gen. Cent., NIID, 4. Grad. Sch. Med., Tokushima Univ.)
[2P-268]Preparation and biological activity evaluation of thermoresponsive lipid nanoparticles using an apolipoproteinA-I-derived peptide
○Haruka Kurita1, Yu Mizukami1, Reina Nakanishi1, Shiori Shibukawa1, Ryosuke Fukuda1, Fumitake Kawanishi1, Yoshinori Nagai1, Tatsuya Murakami1,2 (1. Graduate School of Toyama Prefectural University, 2. iCeMS, Kyoto University)
[2P-269]Analysis of hypothetical protein YmjA, which is predicted to be related to Putrescine utilization pathway in Escherichia coli
○Kohei Iwasaki1, Midori Kurose1, Koji Hongo1, Daisuke Kusanagi1, Naoki Nemoto1 (1. Dept. of Life Sci., Grad. Sch. of Adv. Eng., Chiba Ins. of Tec.)
[2P-270]mRNA-display selection of receptor-recognizing antibody-fragments for hepatocyte-specific DDS
○Naoya Sato1, Taihei Nagafuchi1, Rio Yamamoto1, Rikako Kato1, Kei Fujiwara1, Nobuhide Doi1 (1. Department of Biosciences and Informatics, Keio University)
[2P-271]Disulfide bond-induced stabilization of the FANCM-CENP-SX complex for structural analysis of its role in genome integrity
○Sho Ito1, Tatsuya Nishino1 (1. Tokyo university of science)
[2P-272]Elucidation of the mechanism of CsgA Aggregation inhibition by CsgI, a periplasmic inhibitor of Curli amyloid formation in Escherichia coli
○Nozomi Matsuyoshi1,2, Hirotaka Chuta1,2, Hiroaki Kobayashi1,2, Hiroshi Ogasawara2,3,4,5 (1. Department of Applied Biology, Graduated School of Science and Technology, Shinshu Univ., 2. Research Center for Advanced Science and Technology, Division of Gene Research, Shinshu Univ., 3. Academic Assembly School of Humanities and Social Sciences Institute of Humanities, Shinshu Univ., 4. Renaissance Center for Applied Microbiology, Shinshu Univ., 5. Institute for Fiber Engineering, Interdisciplinary Cluster for Cutting Edge Research, Shinshu Univ.)
[2P-273]Turnover prediction using protein language model and analysis of accuracy related factors
○Koki Ishino1, Yuting Liu1, Akiyasu C Yoshizawa1, Shujiro Okuda1 (1. Medical AI Center, Niigata University School of Medicine)
[2P-274]Screening of desiccation-sensor proteins in the anhydrobiotic tardigrade Hypsibius exemplaris
○Saori Motomura Harada1, Sae Tanaka1,2, Kazuharu Arakawa1,2 (1. IAB, Keio Univ., 2. ExCELLS, NINS)
[2P-275]Is the fate of Tim50 under different carbon-source conditions affected by a tRNA environment during translation?
○Takumi Tamura1, Akihisa Nagai1, Sachiko Hayashi1, Tohru Yoshihisa1 (1. Graduate School of Science, University of Hyogo)
[2P-276]Structural analysis of anti-ACE2 monoclonal antibody inhibiting SARS-CoV-2 and ACE2 complex
○Norito Harada1, Yasuomi Miyashita1, Sisi Chen1, Masato Kawasaki2, Toshiya Senda2, Daisuke Akazawa3, Koichi Watashi3, Takeshi Murata1, Satoshi Ogasawara1 (1. Laboratory of Biostructural Chemistry (Chiba), 2. High Energy Accelerator Research Organization, 3. National Institute of Infectious Diseases)
[2P-277]In vitro selection of collagen-binding vascular endothelial growth factor containing genetically encoded mussel-inspired adhesive amino acid
Takuya MIWA1,2, Akiko YUMOTO1, Seiichi TADA1, Shin Woong KIM1, Shinhye PARK1, Noriko MINAGAWA1, Takayoshi MATSUDA1, Kazumasa OHTAKE1, Yoshihiro SHIMIZU1, Kensaku SAKAMOTO1, Toshiro AIGAKI2, Yoshihiro ITO1,2, ○Takanori UZAWA1 (1. RIKEN, 2. Tokyo Metropolitan University)
[2P-278]Analysis of the RNA-binding activity of the small GTPase Rac1
○Tomoka Yoshida1, Michinori Toriyama1, Ikuoko Yao1 (1. Kwansei Gakuin University)
[2P-279]Development of hemimethylated CpG detection method using methyl-CpG-binding domain fused luciferase and fluorescently modified probe DNA
○Ayumu Hokamura1, Wataru Yoshida1 (1. Tokyo Univ. of Tech.)
[2P-280]Single molecule dynamics analysis of the mitochondrial protein import gate
○Nanako Kobayashi1, Kana Kuzasa1, Romain Amyot2, Shiho Kawai1, Yuta Imai1, Kenichiro Imai3, Noriyuki Kodera2, Toshiya Endo4,5, Yuhei Araiso1 (1. Dept. of Clin. Lab. Sci., Div. of Health Sci., Kanazawa Univ., 2. WPI-NanoLSI, Kanazawa Univ., 3. Cellular and Molecular Biotechnology Research Institute, AIST., 4. Fac. of Life Sci., Kyoto Sangyo Univ., 5. Inst. of Protein Dynamics, Kyoto Sangyo Univ.)
[2P-281]Functional characterization of a novel metal ion-dependent alginate lyase belonging to the PL17 family
○Sora Fukui1, Taichi Endo Takasuka1,2, Brian G Fox1,3 (1. Research Faculty of Agriculture, Hokkaido University, 2. Global Food Resources, Hokkaido University, 3. University of Wisconsin–Madison)
[2P-282]Identification of DNA-binding recognition sequence of clock-related protein Pex
○Momoka Kodama1, Hiroshi Sato2, Masahiro Ishiura2, Risa Mutoh3 (1. Graduate school of science Toho university, 2. Center for Gene Research, Nagoya University, 3. Faculty of science Toho university)
[2P-283]The Role of O-fucosylation of Coagulation Factor XII in the Acquirement of Structural Stability During Biosynthesis.
○Marina Chikaraishi1, Sumika Nakamura1, Kyoko Aikawa1 (1. Ochanomizu Univ.)
[2P-284]E3 ligase Praja1 regulates DNA damage repair through degradation of histone variant H2A.X
○Kotaro Kawasaki1, Chisato Oyama2, Wataru Onodera1, Toru Asahi3,4 (1. Department of Advanced Science and Engineering, Waseda Univ., 2. Comprehensive Research Organization, Waseda Univ., 3. Faculty of Science and Engineering, Waseda Univ. , 4. Research Organization for Nano & Life Innovation, Waseda Univ.)
[2P-285(2PS-14-04)]Still Enigmatic: Phosphate Export Mechanisms in Eukaryotic Cells
– Can Simple Yeast Genetics Provide the Answers?
Tochi Komamura1, Masahiro Takado2, Nene Sakurai1, Hiyori Takechi1, Tomohiro Matsumoto2, ○Kojiro Takeda1 (1. Konan Univ., 2. Kyoto Univ. Biostudies)
[2P-286]Is polyphosphate synthesis ‘in vacuoles’ important for cellular proliferation in Schizosaccharomyces pombe?
○Hiyori Takechi1, Kaho Fujiyama1, Karin Nose2, Kanon Tsukuda2, Kaoru Takegawa3, Kojiro Takeda1,2 (1. Konan university, 2. Konan univ., 3. Kyushu university)
[2P-287]Shp2, a novel phosphate efflux enhancer, contributes to high phosphate tolerance
○Tochi Komamura1, Tomoki Nishimura1, Naoki Ohta1, Masahiro Takado2, Tomohiro Matsumoto2, Kojiro Takeda1 (1. Konan Univ., 2. Kyoto Univ.)
[2P-288]Screening for suppressors of polyphosphate toxicity in S. pombe
○Rumi Okuyama1, Kaho Fujiyama1, Yamaguchi Rei2, Hatori Machika2, Miwatari Aoi2, Takeda Kojiro1 (1. Konan University, 2. Konan Univ.)
[2P-289]Analysis of the mechanism of human phosphate efflux promoting factor Xpr1 by mutagenesis using humanized fission yeast.
○Nene Sakurai1, Ryoma Ikegawa2, Kouta Yamamoto2, Hiyori Takechi1, Masahiro Takado3, Tomohiro Matsumoto3, Kojiro Takeda1,2 (1. Konan University, 2. Konan Univ., 3. Kyoto University)
[2P-290]A novel reactive carbonyl species scavenger and its activity to inhibit the generation of advanced glycation end products found in the yeast Saccharomyces cerevisiae
○Ryo Nasuno1, Hiroshi Takagi2 (1. EGBRC, Kobe Univ., 2. IRI, NAIST)
[2P-291]Real-time analysis of lactate-secretion inhibition by MCT1 inhibitor aCHC using Tandemly Connected NMR
○Naoya Tochio1, Takanori KIgawa1 (1. RIKEN BDR)
[2P-292]Analysis of dopamine Long-Chain acylation by the PLAAT family
○Yuki Maemoto1, Moeha Maeda1, Hinata Matsui1, Motohide Aoki1, Toru Uyama2, Tomonari Umemura1, Natsuo Ueda2, Minoru Yoshida3, Akihiro Ito1,3 (1. Tokyo Univ. of Pharm. and Life., 2. Kagawa Univ., 3. RIKEN CSRS.)
[2P-293]Data collection on the spatial distribution of plant specialized metabolites using imaging mass spectrometry.
○Tetsuya Mori1, Noriko Kamiya Takeda1, Mai Yamamoto Uzaki1, Tomoko Nishizawa1, Kiminori Toyooka1, Masami Hirai1 (1. RIKEN)
[2P-294]Development of a high-precision DNA assembly method for long-chain biosynthetic gene clusters
○Tomoki Takeda1,2, Misaki Aso1, Hiroko Ueda1, Shotaro Kato1,2, Satoshi Yuzawa1,2 (1. Inst. Adv. Biosci., Keio Univ., 2. Syst. Biol. Prog. Grad. Sch. Media & Governance, Keio Univ.)
[2P-295]Elucidation of the function of sialylated glycoproteins with St6galnac quadruple knockout mice developing hydrocephalus
○Yuka Murakami1,2, Yuno Seike1,3, Hiroyuki Izumi1,3, Sayaka Fuseya1,4, Satoru Takahasi1, Takashi Kudo1 (1. Dept. Ana. Emb., Inst. Med., Univ. Tsukuba, 2. Program in Human Biology, SIGMA, Univ. Tsukuba, 3. Mas. Pro. Med. Sci., Grad. Sch. Comp. Hum. Sci., Univ. Tsukuba, 4. Mol. Cell. Glyco. Res. Gro., Cell. Mol. Bio. Res. Inst., AIST)
[2P-296]Physiological role of pyruvate kinase in cyanobacteria expressed in response to nitrogen conditions.
○Masahiro Karikomi1, Kanako Iseki2, Honoka Suzuki2, Ryo Kariyazono2, Takashi osanai2 (1. Meiji University Graduate School, 2. Meiji University)
[2P-297]Exploring the biosynthetic pathway of glycolipid MPIase that catalyses membrane protein insertion and preprotein translocation
○Yuuta Tadika1, Youjung Han2, Kohki Fujikawa3, Keiko Shimamoto3, Ken-ichi Nishiyama1,2 (1. Dept. of Biol. Chem., Fac. of Agriculture, Iwate Univ., 2. UGAS, Iwate Univ., 3. Suntory Foundation for Life Sciences)
[2P-298]Analysis of the substrate recognition mechanism in microlipophagy in the yeast Saccharomyces cerevisiae
○TAKUMI NAKATSUJI1, KOSUKE SHIRAISHI1, MASAHIDE OKU2, YASUYOSHI SAKAI1 (1. Kyoto university, 2. KYOTO UNIVERSITY of ADVANCED SCIENCE)
[2P-299]Identification of metabolite dynamics in the cauda epididymis after 4-degree cold storage by metabolomics analysis
○RYUSEI MAEDA1, Keisuke Masuda1, Satohiro Nakao1, Toru Takeo1 (1. Div. of Rrprod. Eng. CARD. Kumamoto Univ)
[2P-300]The differential alternative splicing pattern in caste of social insects
○Yuhang Jia1, Takashi Makino1 (1. Tohoku University)
[2P-301]Formulation of the Optimum Temperature Based on the Molecular Mechanism of Adenylate Kinase 1 Adapted to the Body Temperature of Chordates
○Tatsuya Yamamoto1, Azumi Wada1, Honoo Satake1 (1. SUNTORY FOUNDATION for LIFE SCIENCES)
[2P-302]Comprehensive Whole Genome Sequencing Analysis of Methicillin-resistant Staphylococcus aureus from a Regional Hospital in Central Taiwan
○Yung-Chieh Wu1, Tsung-Hua Wu2,3, Wen-Sheng Yeh1, Mei-Hsiu Wan1, Ying-Tsong Chen1,2,4 (1. Graduate Institute of Genomics and Bioinformatics, National Chung Hsing University, Taiwan, 2. Ph.D. Program in Medical Biotechnology, National Chung Hsing University, Taiwan, 3. Department of Pediatrics, Show Chwan Memorial Hospital, Changhua, Taiwan, 4. Institute of Molecular and Genomic Medicine, National Health Research Institutes, Taiwan)
[2P-303]Small Ribosomes and Frequent Insertion Sequences in rRNA Genes of CPR Bacteria
Megumi Tsurumaki1,2, Asako Sato1, Motofumi Saito1, ○Akio Kanai1,2,3 (1. Inst. Adv. Biosci, Keio Univ., 2. Syst. Biol. Grad. Sch. Media & Governance, Keio Univ., 3. Environment & Info. Studies, Keio Univ.)
[2P-304]Tracing the evolution of the ASP gene in HIV-1
○Miu Naruki1,2, Asaka Yanada1, Motofumi Saito1, Shohei Nagata1, Hironori Sato4, Akio Kanai1,2,3 (1. Institute for Advanced Biosciences, Keio University, 2. Systems Biology Program Graduate School of Media and Governance, Keio University, 3. Department of Environment and Information studies, Keio University, 4. National Institute of Infectious Diseases)
[2P-305]Genetic, transcriptomic and translatomic characterization of newborn genes that emerged in the Arabidopsis thaliana genome during its diversification
○Shoma Morita1, Yusei Shigematsu1, Takuya Nakagawa1, Takuto Nakatsuji2, Soichirou Satoh1,2 (1. Grad.Sch.Life Env. Sci.,Kyoto Pref Univ., 2. Fac.Sch.Life Env. Sci.,Kyoto Pref Univ.)
[2P-306(2PS-03-05)]A Genomic and Phylogenetic Analysis of Human Variant Methicillin-Resistant S. aureus Clonal Complex 398 in Taiwan
○Tsung-Hua Wu1,2,3, Wen-Sheng Yeh4, Mei-Hsiu Wan4, Yung-Chieh Wu4, Yu-Ping Fang5, Chun-Yi Lee3,5, Ying-Tsong Chen1,4,6 (1. Ph.D. Program in Medical Biotechnology, National Chung Hsing University, Taiwan, 2. Department of Pediatrics, Show Chwan Memorial Hospital, Taiwan, 3. Department of Post Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taiwan, 4. Graduate Institute of Genomics and Bioinformatics, National Chung Hsing University, Taiwan, 5. Department of Pediatrics, Chang Bing Show Chwan Memorial Hospital, Taiwan, 6. Institute of Molecular and Genomic Medicine, National Health Research Institutes, Taiwan)
[2P-307]Genome analysis of Heptathela kimurai reveals the origin of spider silk.
○Chisato Ishiwata1,2, Phillip Yamamoto1,3, Hiroyuki Nakamura1,4, Akio Tanikawa5, Nobuaki Kono1,2,3 (1. Inst. Adv. Biosci., Keio Univ., 2. Dept. Environ. Info. Stud., Keio Univ., 3. Syst. Biol. Prog. Grad. Sch. Media & Governance, Keio Univ., 4. Spiber Inc., 5. Lab. Biodiv. Sci., Fac. Agric., Univ. Tokyo.)
[2P-308]Experimental evolution of antibiotic resistance in Lactobacillus acidophilus NRIC 1547T
○Leo Kajiyoshi1, Naoto Tanaka1,2, Yuu Shiwa1, Akifumi Nishida1, Nobuyuki Fujita1 (1. Faculty of Life Sciences, Tokyo University of Agriculture, 2. NODAI Culture Collection Center, Tokyo University of Agriculture)
[2P-309(2PS-14-07)]Elucidation of the solute selectivity mechanism of Aqp10 by comparative physiological analysis
○Ayumi Nagashima1,2, Kazutaka Ushio2, Hidenori Nishihara2,3, Jin Akimoto2, Akira Kato1,2, Tadaomi Furuta1,2 (1. Science Tokyo, 2. Tokyo Tech., 3. Kindai Univ.)
[2P-310]Lineage-specific intron turnover in slc26a1 and slc26a2 and a role for transposon insertion in the intron gain
○Akira Kato1,2, Kota Torii2, Ayumi Nagashima1,2, Masaki Kajikawa1,2 (1. Science Tokyo, 2. Tokyo Inst. Tech.)
[2P-311]Sharks and rays share long-standing sex chromosomes without dosage compensation
○Taiki Niwa1,2, Yoshinobu Uno3, Yuta Ohishi4, Susumu Hyodo5, Shigehiro Kuraku1,4 (1. NIG, 2. SOKENDAI Genetics, 3. Tokyo Univ., 4. RIKEN BDR, 5. AORI・Tokyo Univ.)
[2P-312(2PS-03-04)]Genome scrambling in the Tree of Life: when do synteny losses correlate with species boundaries?
○Charles Plessy1 (1. Okinawa Institute of Science and Technology Graduate University (OIST))
[2P-313]A humanized NOVA1 splicing factor alters mouse vocal communications
○Yoko Tajima1, Robert B. Darnell1 (1. The Rockefeller University)
[2P-314]Elucidating the evolutionary mechanism for recognition of the E3 ubiquitin ligase Praja to Tau protein using an ancestral sequence reconstruction
○Hikaru Kurahashi1, Shiho Aoki2, Toru Asahi3,4, Wataru Onodera5 (1. Department of Life Science and Medical Bioscience, Waseda Univ., 2. Graduate School of Advanced Science and Engineering, Waseda Univ., 3. Faculty of Science and Engineering, Waseda Univ., 4. Research Organization for Nano & Life Innovation, Waseda Univ., 5. Graduate School of Advanced Science and Engineering, Department of Advanced Science and Engineering, Waseda Univ.)
[2P-315]Comparative analysis of inter-microchromosomal in vertebrates
○Ryusei Koike1, Yuichiro Hara1 (1. Kitasato Univ. Grad. Sch. Front. Eng.)
[2P-316]Nano dynamics observation of Afamin and Afamin/Wnt3a using High Speed Atomic Force Microscopy
○HIKARU ICHIDA1, Kosuke Mizuno1,2, Satoshi Toda2, Noriyuki Kodera3 (1. Division of Nano Life Science, Graduate School of Frontier Science Initiative, Kanazawa University, 2. Institute for Protein Research, Osaka University, 3. Nano Life Science Institute, Kanazawa University)
[2P-317(2PS-02-02)]Live-Organismal Transcriptomics
○Kotaro Torii1, Hirofumi Shintaku1,2 (1. Riken, 2. Kyoto Univ.)
[2P-318]Construction of a Truncated var2CSA Baculovirus Vector and Evaluation of Gene Transduction Efficiency in Human Cancer Cells
○Takahiko Tamura1 (1. Sch. of Pharmacy, Kanazawa Univ.)
[2P-319]Creation of a molecular imaging atlas of brain tissue
○Wakana Takeuchi1, Mirei Ishikawa1, Noriko Oshima1, Shino Homma Takeda2, Nobuko Tokuda1, Tadayuki Ogawa1 (1. Dokkyo Medical Univ., 2. QST)
[2P-320]DNABank Quality Inspection Data Reveal International Nucleotide Sequence Database Errors
○Nobuatsu Nakamura1, Tetsushi Iida1, Junichi Onami1, Shotaro Kishikawa1, Junko Kijima1, Yukari Kujime1, Megumi Sakayori1, Syunichi sasanuma1, Kenichi Nakashima1, Shingo Nozaki1, Stoshi Hasegawa1, Kazuhito Yoshida1, Takehide Murata1, Yoshihiro Miwa1 (1. RIKEN BRC. DNABank)
[2P-321]Identification of Iron-Modulating Drugs Using a Fluorescence-Based Iron Reporter
○JOAN JEPKOSGEI KOMEN1, AYATO MAEDA1, AKIHIRO NITA1, TOSHIRO MOROISHI1 (1. Kumamoto University)
[2P-322]Characteristics of milk exosomes extracted from commercial milk with different fat concentrations
○Kana Matsumoto1,3, Yuzuki Sawada2, Noa Hatanaka2, Mizuho Ohashi2, Mitsuru Chiba1,3 (1. Department of Bioscience and Laboratory Medicine, Graduate School of Health Sciences, Hirosaki University, 2. Department of Medical Technology, School of Health Sciences, Hirosaki University, 3. Research Center for Biomedical Sciences, Hirosaki University)
[2P-323]Structure, Barrier, and Evolution of Skin Observed by Mass Spectrometry Imaging
○Taichi Ochiai1, shown Tokoro1, Noriko Oshima1, Junichi Kamiie2, Ken Igawa1, Tadayuki Ogawa1 (1. Dokkyo Medical Univ., 2. Azabu Univ.)
[2P-324]Biodegradation of P-Life-containing PP and its mechanism
○Ayaka Futagi1, Ying Huang1, Isao Toyama2, Yoshito Abe3, Shuji Uchiyama4, Kenji Miyamoto1 (1. Keio university, 2. P-Life Japan, Inc., 3. SI Jushisangyou, Inc., 4. ITO EN, LTD.)
[2P-325]Functional Analysis of TgCLP1 Secreted During Toxoplasma gondii Reactivation
○Hironori Bando1,2, Yuho Murata3, Han Yongmei3, Tatsuki Sugi4,3, Yasuhiro Fukuda2, Kentaro Kato2,3 (1. Asahikawa Medical University, 2. Laboratory of Sustainable Animal Environment, Tohoku University, 3. NRCPD, Obihiro University, 4. International Institute for Zoonosis Control, Hokkaido University)
[2P-326]Metabolic regulation by tissue-specific splicing variants in the mouse liver
○Masaki Shirai1, Shinya Kuroda1 (1. Tokyo Univ.)
[2P-327]Direction-dependent fluctuations of rotational trajectories in E. coli flagellar motors
○Kohei Ishiamru1, Yumiko Uchida1, Akihiko Ishijima1, Hajime Fukuoka1 (1. Graduate School of Frontier Biosciences Osaka University)
[2P-328]Detecting Neuropeptide F using new antibodies and ELISA system
○Maki Higashida1, Naoki Okamoto2, Ryo Hoshino1,2, Yuto Yoshinari2,3, Tomoe Kobayashi4, Makoto Matsuyama4, Jiangtian Chen5, Marc Tatar5, Ryusuke Niwa2 (1. Graduate school of Science and Technology, University of Tsukuba, 2. TARA, University of Tsukuba, 3. Institute for Molecular and Cellar Regulation, Gunma University, 4. Division of Molecular genetics, Shigei Medical Research Insutite, 5. Depertment of Ecology, Evolution and Organismal Biology, Brown Univ)
[2P-329]Encapsulation and photo-mediated release of proteins from droplets composed of caged phase-separating peptides
○Seiichi Fujiwara1, Akinari Bando1, Kazunori Watanabe1, Mari Takahara1, Yuuki Kanazaki2, Mizuki Kitamatsu2, Takashi Ohtsuki1 (1. Grad. Sch. of Interdiscip. Sci. and Eng. in Health Sys., Okayama Univ, 2. Dept. of Mol. and Mat. Eng., Grad. Sch. of Sci. and Eng., Kindai Univ.)
[2P-330]Protein pairs which change FRET based fluorescent color by an intercellular pH indicator to detect organophoshorus pesticides
○Shuzo Homma1, Sohki Miyazaki1, Takuo Akimoto1 (1. Tokyo University of Technology)
[2P-331]Detection of landmines using FRET based Microbial biosensor
○Taiga Yoshizawa1, Kai Nishimura1, Suzuna Nakajima1, Takuo Akimoto1 (1. Tokyo University of Technology)
[2P-332]A microbial BOD biosensor intercellular ATP measurement of Saccharomyces cerevisiae
○Yuto Kanno1, Yuta Tateno1, Takuo Akimoto1 (1. TOKYO UNIVERSITY OF TECHNOLOGY)
[2P-333]Differences in microbial community structure at different depths of boreholes in the Koishi site of the Tempoku Coalfield, Hokkaido, Japan
○Akio Ueno1, Kiyoshi Sato1, Shuji Tamamura1, Takuma Murakami1, Hidenori Inomata1, Satoshi Tamazawa1, Hideo Aoyama2, Hayao Nagai2, Atsutaro Tadokoro2, Kazunari Mikami2, Takeshi Naganuma3, Toshifumi Igarashi1,4 (1. H-RISE, 2. MUCC, 3. Hiroshima Univ., 4. Asahikawa College, KOSEN)
[2P-334]Insecticidal synergism between mosquito-larvicidal Mpp46Ab and Cry4Aa from Bacillus thuringiensis
○Tohru Hayakawa1, Syun Yamaoka1, Mami Asakura1, Toru Ide1 (1. Okayama University)
[2P-335]Characteristics of Bioluminescence Activity of Fluorine Substituent Coelenterazine Analogues
○Genta Kamiya1, Nobuo Kitada2, Tadaomi Furuta3, Sung-Bae Kim4, Shojiro Maki1,5 (1. Dept. of Eng. Sci., Grad. Sch. of Info. Eng., UEC, 2. Res Faci., UEC, 3. Dept. of Life Sci and Tech., Tokyo Tech Univ, 4. EMIR., AIST, 5. CNBE., UEC)
[2P-336]The fully automated detection of sister chromatid cohesion defects using YOLOv8
○Shinya Matsumoto1, Kiyoshi Nishikawa1, Kan Okubo1, Takuya Abe2 (1. Tokyo Metropolitan Univ., 2. Tohoku Medical and Pharmaceutical Univ.)
[2P-337]Gaining insights into the dynamics and molecular regulation of the kinetochore using proximity labelling
○Shreyas Sridhar1, Reiko Nakagawa2, Tatsuo Fukagawa1 (1. Laboratory of Chromosome Biology, Graduate School of Frontier Biosciences, Osaka University, Suita, Osaka 565-0871, Japan. , 2. Laboratory for Phyloinformatics, RIKEN Center for Biosystems Dynamics Research (BDR), Kobe 6500047, Japan.)
[2P-338]Improvement of Chromosomal mobilization Efficiency between Actinomycetes Streptomyces Bacteria
○Yusaku Kobayashi1, Akane Mizowaki1, Masakazu Kataoka1 (1. Shinshu University)
[2P-339]Alteration of centromeric transcription impairs faithful kinetochore assembly
○Anna Suzuki1,2, Saho Matsui1,2, Toru Hirota1,2 (1. Div. Exp. Pathol. Cancer Inst. JFCR, 2. Dept. JFCR., Science Tokyo)
[2P-340]Chromatin axis formation during meiosis in fission yeast
○Yasushi Hiraoka1, Takeshi Sakuno1, Yasuto Murayama2 (1. Osaka University, 2. National Institute of Genetics)
[2P-341]Role of the CENP-T complex for centromere specification in Mucor lusitanicus
○Yaoyi Zhou1, Haruhiko Asakawa 1, Shreyas Sridhar1, Mariko Ariyoshi1, Tatsuo Fukagawa1 (1. Osaka Univ.)
[2P-342]Analysis of stress to the loss of the expression plasmid for a heterologous protein in budding yeast
○Yuzuki Nara1, Takumi Sato2, Miku Horiuchi2, Suzuki Saika2, Hitomi Nakamura2, Shiori Tobinaga1, Noriyuki Suka1,2 (1. Dep. of Chem., Grad. Sch. of Sci. Eng., Meisei Univ. Tokyo, Japan, 2. Prog. in Chem. Life Sci., Sch. of Sci. Eng., Meisei Univ. Tokyo, Japan)
[2P-343]Expansion microscopy: Super-resolution fluorescence and Raman imaging by expanding cells
○Tsubasa Kobayashi1, Ren Shibuya2, Shinji Kajimoto1,2, Takakazu Nakabayashi1,2 (1. Faculty of Pharmaceutical Sciences, Tohoku University, 2. Graduate School of Pharmaceutical Sciences, Tohoku University)
[2P-344]Construction and performance evaluation of a novel artificial chromosome using neocentromere formation in fission yeast
○Kento Furukawa1, Kojiro Ishii1 (1. Grad. Sch. of Kochi Univ. of Tech.)
[2P-345]Imaging analysis of the nucleus of Hutchinson-Gilford progeria model cells using Scanning Transmission X-ray Microscopy (STXM)
○Kurumi Nishimagi1, Kentaro Fuji2, Tohru Araki3, Masahiko Harata1 (1. Graduate school of Agricultural science Tohoku University, 2. QST, 3. UVSOR Synchrotron Facility, Institute for Molecular Science)
[2P-346]Investigation of the method for identifying the domains involved in the inhibition of cellular growth by Xenopus laevis linker histone H1A heterologously expressed in Saccharomyces cerevisiae
○Tsubasa Kataoka1, Shun Muto2, Kodai Shiba1, Noriyuki Suka1,2 (1. Dep. of Chem., Grad. Sch. of Sci. Eng., Meisei Univ. Tokyo, Japan, 2. Prog. in Chem. Life Sci., Sch. of Sci. Eng., Meisei Univ. Tokyo, Japan)
[2P-347]The role of ELYS during nuclear membrane reformation
○Kei Makiyama1, Richard Wing Wong2,3, Masaharu Hazawa2,3 (1. Transdisciplinary. Sci. Grad. Sch., Front. Sci. Initiative. Div., Kanazawa Univ., 2. Nano life Sci. Inst., Kanazawa Univ., 3. Cell-Bio. Res. Unit., Front. Sci. Initiative. Inst., Kanazawa Univ.)
[2P-348]Nucelar transport fator importin alpha slides along DNA and targets cargo proteins to DNA
○Kazuya Jibiki1, Trishit Banerjee2,3, Hinata Sugasawa4, Kiyoto Kamagata5, Noriko Yasuhara1,4 (1. Dep. of Biosci., College of Humanities and Sci., Nihon Univ., 2. IMRAM, Tohoku Univ., 3. Dep. of Chem., Grad. Sch. of Sci., Tohoku Univ., 4. Grad. Sch. of Integrated Basic Sci., Nihon Univ., 5. Faculty of Eng. and Grad. Sch. of Eng., Gifu Univ.)
[2P-349]Exploration and function of novel regulators of telomere length in S. pombe
○Masako Matsunaga1, Syumari Yamada1, Hyuga Umehara2, Kohei Nishino3, Hidetaka Kosako3, Shiho Ogawa1,2, Katsunori Tanaka1,2 (1. Dept. of Biosci., Sch. of Sci. and Tech., Kwansei Gakuin Univ., 2. Dept. of Biosci., Sch. of Biol. and Envi. Sci., Kwansei Gakuin Univ., 3. Inst. Adv. Med. Sci., Tokushima Univ)
[2P-350]Meiotic DNA break machinery modulates chromosome-axis organization
○Masaru Ito1, Akira Shinohara1, Kunihiro Ohta2 (1. Osaka Univ., Inst. for Protein Res., 2. The Univ. of Tokyo, Dept. Life Sci.)
[2P-351]Rapid control of nuclear size and shape in Xenopus laevis fertilized eggs
Mizuki Ikeda1, Yuto Tanaka1, Tatsuya Shohoji1, Misako Ohama1, ○Yuki Hara1 (1. Yamaguchi University)
[2P-352]Diverse roles of kinetochore components in bean bug Riptortus pedestris
○Momoka Nagao1, Takumi Yoshikawa1, Mizuko Osanai-Futahashi1 (1. Ibaraki Univ.)
[2P-353]Mitotic chromosome organization captured from nanoscale chromatin dynamics
○Kayo Hibino1,2,3, Yuji Sakai4, Masato Kanemaki1,2, Kazuhiro Maeshima1,2 (1. National Institute of Genetics, 2. SOKENDAI, 3. PRESTO, JST, 4. Yokohama City Univ.)
[2P-354]Functional Analysis and Method Development for Studying Gene Expression Regulation via 3D Genome Structures between Adjacent Genes
○Yik-Lok Claire Chung1, Hideki Tanizawa1, Noma Ken-ichi1 (1. Div. Genome Biol., IGM, Hokkaido Univ.)
[2P-355]Detailed 3D Structural Analysis of Convergent Gene Pairs in the Fission Yeast Genome
○Hideki Tanizawa1, Yik-Lok Claire Chung1 (1. Institute for Genetic Medicine, Hokkaido University)
[2P-356]Analysis of intrinsically disordered regions of coilin in the formation and function of Cajal Body
○Ryota Yokoyama1, Hiroshi Maita1, Shinichi Nakagawa1 (1. Hokkaido University)
[2P-357(2PS-05-06)]From Systematic Identification of Human Non-Membranous Structures to Understanding Neurodegenerative Disease
○shin Kobayashi1, Yoshifumi Kawamura2, Eriko Fukuda1, Nami Sugita3, Naoki Goshima4, Shungo Adachi 5 (1. National Institute of Advanced Industrial Science and Technology , 2. Fukushima Translational research Foundation, 3. Japan Biological Informatics Consortium, 4. Musashino University, 5. National Cancer Center Research Institute)
[2P-358]Analysis of G-quadruplex using a novel detection reagent
○YUSUKE NARITA1, Norio Hirakawa1, Makoto Tsuzaki1, Masakazu Nakakubo1, Munetaka Ishiyama1, Takashi Sakamoto2,3 (1. DOJINDO LABORATORIES, 2. Faculty of Systems Engineering, Wakayama University, 3. Graduate School of Systems Engineering, Wakayama University)
[2P-359(2AS-11-06)]Spatial regulation of ribosomal RNA transcription by phase separation and transition
○Satoru Ide1, Yasuto Murayama2,3, Kazuhiro Maeshima2,3 (1. Tokyo Metropolitan Institute of Medical Science, 2. National Institute of Genetics, 3. SOKENDAI)
[2P-360]Functional analysis of the specific structure GRR of Rbp1 in cyanobacterium Synechocystis sp. PCC 6803
○Kenta Kakazu1, Sotaro Machida1, Satoru Watanabe1 (1. Tokyo Univ. Agric.)
[2P-361]Discovery of arsenite-specifically formed Hsp90 granules distinct from stress granules in fission yeast
○Naofumi Tomimoto1, Teruaki Takasaki1, Reiko Sugiura1 (1. Kindai Univ, Japan)
[2P-362]Understanding the molecular condensates formation under extreme light stress conditions in Arabidopsis
○Wen Dee Ong1, Hidefumi Hamasaki1, Setsuko Shimada1, Yukio Kurihara, Naoshi Dohmae1, Minami Matsui1 (1. RIKEN CSRS)
[2P-363(2AS-07-05)]Comprehensive analysis of the effects of protein structure formation factors in endoplasmic reticulum on protein secretion
○Akane Fueki1, Kazuya Tsumagari2, Masaki Matsuo1, Kinnosuke Yahiro3, Yuta Suzuki4, Makoto Kashima4, Koshi Imami2, Satoshi Ninagawa1,5 (1. Bioresour. Sci., Grad School of Agr. Sci., Kobe Univ., , 2. RIKEN Center for IMS, 3. Faculty of Pharm. Sci., Kyoto Pharmaceutical Univ., 4. Deartment of biology, Faculty of Science, Toho Univ., 5. Biosignal Research Center, Kobe University)
[2P-364(2AS-07-06)]ATPases regulate the subcellular localization of single-spanning membrane proteins
○Suzuka Ono1, Shunsuke Matsumoto2, Toshiya Endo1 (1. Fac. of Life Sci., Kyoto Sangyo Univ., 2. Fac. of Agric., Grad. Sch. of BBS., Kyushu Univ.)
[2P-365]A potential role of the microtubule-associated protein NudC in ribosome biogenesis homeostasis
○Duoduo Shi1, Yuko Shimada Niwa2, Naoki Okamoto2, Yuya Ohhara3, Akira Nakamura4, Wei Sun5, Ryusuke Niwa2 (1. Degree Programs in Life and Earth Sciences, Graduate School of Science and Technology, University of Tsukuba, Japan, 2. Life Science Center for Survival Dynamics, TARA, University of Tsukuba, Japan , 3. Laboratory of Human Genetics, School of Food and Nutritional Sciences, University of Shizuoka, Japan , 4. Institute of Molecular Embryology and Genetics, Kumamoto University, Japan, 5. School of Life Sciences, Chongqing University, China)
[2P-366]β-arrestin is essential for GPCR translocation to caveolae
○Gaku Nakamura1, Masataka Yanagawa1, Asuka Inoue1,2 (1. Tohoku University, 2. Kyoto University)
[2P-367]Degradation and quality control mechanism of microtubule-associated protein tau by E3 ubiquitin ligase Praja1.
○Shiho Aoki1, Kotaro Kawasaki1, Kazuki Imadegawa1, Mizuho Oishi1, Tomoya Uchida1, Naoki Kato1, Shigeo Sakuragi2, Hiroko Bannai2, Toru Asahi2,3, Wataru Onodera1 (1. Waseda Univ. Dept. of Adv. Sci. & Eng., 2. Faculty of Sci. & Eng., 3. Res. Org. Nano & Life, Waseda University)
[2P-368]Resveratrol Reduces Melanosome Content in Skin Fibroblasts by Activating Autophagy and Antioxidant Pathways: Potential for Dark Spot Treatment
○Ayano Satoh1 (1. Okayama University)
[2P-369]The interaction between the import carrier Hikeshi and molecular chaperone HSP70 is modulated by heat, facilitating the nuclear import of HSP70 under heat stress conditions
○Shingo Kose1, Sakie Yoshioka1,2, Yutaka Ogawa1, Ai Watanabe1, Naoko Imamoto1,3 (1. RIKEN CPR, 2. Saitama Univ., 3. Jikei Univ. of Health Sci. Care)
[2P-370]Localization change of spore coat protein of fission yeast
○Tomoki Sakaguchi1, Karina Yoshikawa1, Taro Nakamura1 (1. Osaka Metropolitan University)
[2P-371]Analysis of liver tissue-specific ER stress response in tissue dysfunction caused by disruption of ER homeostasis
○Byungseok Jin1, Kazutoshi Mori1 (1. Kyoto University)
[2P-372]in vitro reconstitution of E. coli twin-arginine translocation (TAT) pathway
○Hanako Nishikawa1, Nachi Yamamoto1, Kotoka Kanno1, Katsuhiro Sawasato1, Miwa Yamada1, Ken-ichi Nishiyama1 (1. Iwate university)
[2P-373]Analysis of clathrin coating formation mechanisms using rapamycin-induced heterodimmerization method
○Yuka Tsuji1, Keiko Miyano, Kokubo Risa, Mitsuishi Akira, Toshima Jiro1 (1. Tokyo University of Science)
[2P-374]Expanding the application of CRISPR/Cas9 knock-in technology using split fluorescent protein in Dictyostelium
○Kensuke Yamashita1, Tetsuya Muramoto1 (1. Toho Univ.)
[2P-375]Effect of inhibition of COPI/COPII- coated vesicle transport on endocytic pathway
○Nanako Murata1, Hiroki Shimamura1, Makoto Nagano2, Junko Toshima3,1, Jiro Toshima1 (1. Dept. of Bio. Sci. and Tech., Tokyo Univ. of Sci, 2. Drug Vac. Dev., NIID, 3. Sch. of Heal. Sci., Tokyo Univ. of Tech)
[2P-376(1AS-15-03)]Regulation of metabolism and cellular function by recycling of plant organelle chloroplasts in mollusc cells.
○Kyota Hamashima1, Kazuki Nishida2, Natsuki Hara1, Hisato Saitoh1,3 (1. Dept. of Biological Science, Grad. Sch. of Sci. and Tech., Kumamoto Univ., 2. Kagoshima City Aquarium, 3. Faculty of Advanced Science and Technology (FAST), Kumamoto Univ.)
[2P-377]Induction of Multinucleated Macrophage FBGC by Plant-Specific Organelle Chloroplasts and the Reutilization of Chloroplasts in Animal Cells
○Natsuki Hara1, Kyota Hamashima1, Arisa Higashi1, Hisato Saitoh1,2 (1. Department of Biological Science, Graduate School of Science and Technology, Kumamoto University, 2. Faculty of Advanced Science and Technology (FAST), Kumamoto University)
[2P-378]Induction of Light-Dependent Cancer Cell Death by ROS Generated from Externally Incorporated Chloroplasts
○Lilingman Fan1, kyota Hamashima1, Hisato Saitoh1,2 (1. Department of Biological Science, Graduate School of Science and Technology, Kumamoto University, 2. Faculty of Advanced Science and Technology (FAST), Kumamoto University)
[2P-379(2MS-02-02)]Manipulation of Mitochondrial and Lipid Droplet Regulations and Classification of their Patterns by Various Fatty Acids
○Koichi Hinokidani1, Hisato saitoh1,2 (1. Department of Biological Science, Graduate School of Science and Technology, Kumamoto University, 2. Faculty of Advanced Science and Technology (FAST), Kumamoto University)
[2P-380]Formation of Micronuclei, Nuclear Envelope Damage, and Altered Localization of Nuclear Transport Factors Induced by Actin and Tubulin Inhibitors
○Arisa Higashi1, Yoichi Miyamoto2, Hisato Saitoh1,3 (1. Department of Biological Science, Graduate School of Science and Technology, Kumamoto University, 2. Laboratory of Biofunctional Molecular Medicine, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), 3. Faculty of Advanced Science and Technology (FAST), Kumamoto University)
[2P-381(3AS-16-05)]Copper-free azido-DBCO click reaction labels and visualizes a group of biomolecules in living human cells.
○Takayuki Seki1, Hisato saitoh1,2 (1. Biology Course, Faculty of Science, Kumamoto University, 2. Faculty of Advanced Science and Technology (FAST), Kumamoto University)
[2P-382]Mechanotransduction in Human Cells in Response to Two Non-Standard Stimuli
○Shinji Kobayashi1, Hisato Saitoh1,2 (1. Department of Biological Science, Graduate School of Science and Technology, Kumamoto University, 2. Faculty of Advanced Science and Technology (FAST), Kumamoto University)
[2P-383]Study on the Interaction Between Plant Biomineral Raphide and Macrophages
○Kazutaka TASHIMA1, Hisato Saitoh1,2 (1. Department of Biological Science, Graduate School of Science and Technology, Kumamoto University, 2. Kumamoto University, 2Faculty of Advanced Science and Technology (FAST), Kumamoto University)
[2P-384(2AS-07-07)]Applying AlphaFold: The Triad Interaction of Autophagy-Initiating ULK Complex in Mammals and its Evolutionary Origin
○Yutaro HAMA1,2, Nobuo N NODA1,2 (1. Inst. for Genet. Med., Hokkaido Univ. , 2. Inst. of Mictrob. Chem. (BIKAKEN))
[2P-385]Role of an autophagy receptor, optineurin, for the intracellular distribution and degradation of lipid droplets in retinal pigment epithelium
○Wataru Otsu1, Hideshi Tsusaki1, Masamitsu Shimazawa1,2 (1. Biomed. Res. Lab., Gifu Pharm. Univ., 2. Mol. Pharmcol., Gifu Pharm. Univ.)
[2P-386]Association between nuclear membrane deformation and viral proliferation in West Nile virus infection
○Keisuke Maezono1, Passawat Thammahakin1, Kentaro Yoshii2, Michiyo Kataoka3, Tadaki Suzuki3, Thuy Duon Thi Ngoc1, Haruto Eguchi1, Hiroaki Kariwa1, Shintaro Kobayashi1,4 (1. Laboratory of Public Health, Faculty of Veterinary Medicine, Hokkaido University, 2. National research Center for the Control and Prevention of Infectious Diseases (CCPID), Nagasaki University, 3. Department of Pathology, National Institute of Infectious Diseases, 4. Institute of Vaccine Research and Development (HU-IVReD), Hokkaido University)
[2P-387(2AS-08-09)]Mitofusin1/2 are required for maintaining the balance of brown adipocyte differentiation.
○Hiroki Shimura1, Shun Nagashima1, Yu Taguchi1, Mami Oikawa1, Toshifumi Fukuda1, Tomoyuki Yamaguchi1 (1. Laboratory of Regenerative Medicine, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences)
[2P-388]Tracking Intracellular ATP Changes in Response to Stress
○Takahito Ayano1, Masamichi Yamamoto1 (1. National Cerebral and Cardiovascular Center)
[2P-389]Characterization of P5BP1, a novel protein interacting with the PTS1 receptor Pex5
○Koki Sakoda1, Kanji Okumoto1,2, Yuri Shirahama1, Yukio Fujiki3,4,5 (1. Sys. Life Sci., Kyushu Univ., 2. Dept. of Biol., Fac. of Sci., Kyushu Univ., 3. Inst. for Adv. Study, Kyushu Univ., 4. Fac. of Arts and Sci., Kyushu Univ., 5. Sch. of Sci, Univ. of Hyogo)
[2P-390]Autophagy Induction by D-Tryptophan and D-Aspartic Acid: A Dive into mTOR-independent Signaling Pathways
○KUN XIE1,2, Wang Jinyun1, Kamimura Miyu1, Hara Taichi1 (1. Waseda University, 2. Hunan Agricultural Univerisity)
[2P-391]A novel synthetic lethal gene that is critical for maintaining cell viability in the presence of a deoxyhypusine synthase inhibitor GC7
○Ken Matsumoto1,2, Rumi Kurokawa1, Megumi Takase1, Takehiro Suzuki3, Naoshi Dohmae3, Minoru Yoshida1,2 (1. Chemical Genomics Res Group, RIKEN CSRS, 2. Seed Cpds Explor Unit Drug Discov, RIKEN CSRS , 3. Biomol Character Unit, RIKEN CSRS)
[2P-392]Contribution of vacuolar amino acid recycle to the survival under nitrogen starvation
○Haruto Nakajo1, Ryogo Okamura2, Shiori Nakagawa2, Miyuki Kawada1,3,4, Takayuki Sekito1,3 (1. Grad. sch. of Agr., Ehime Univ., 2. Fac. of Agr., Ehime Univ., 3. Div. of Cell-Free Sci., PROS, Ehime Univ., 4. Div. of Genetic Research Support , ADRES, Ehime Univ.)
[2P-393]Formation of migrasome-like vesicles and molecular localization induced by hypoosmotic stress on migrating cells
○Koki Yoshikawa1, Shogo Saito1, Masayoshi Tanaka1, Mina Okochi1 (1. Institute of Science Tokyo)
[2P-394]Analysis of the effect of peroxisomal morphology on β-oxidation and de novo synthesis
○Fuya Yamaguchi1, Isshin Shiiba1, Shohei Uchinomiya2, Ayumu Sugiura3, Shun Nagashima4, Shigeru Yanagi1 (1. Gakushuin Univ., 2. Kyushu Univ., 3. Juntendo Univ., 4. Tokyo University of Pharmacy and Life Sciences)
[2P-395]Roles of RhoGEF, Solo in the remodeling of keratin networks in epithelial cell collective migration
○Ukyo Kawasaki1, Riku Maruta1, Mayu Nomura1, Shuhei Chiba1, Kensaku Mizuno1, Kazumasa Ohashi1 (1. Tohoku university)
[2P-396]Functional analysis of RhoGEF, Solo in the remodeling of keratin networks at the cell-cell adhesion sites in epithelial cells
○Riku Maruta1, Ukyo Kawasaki1, Mayu Nomura1, Shuhei Chiba1, Kensaku Mizuno1, Kazumasa Ohashi1 (1. Graduate School of life science, Tohoku University)
[2P-397(2PS-04-06)]ZO-1 shuttles between tight junctions and podosomes riding on ERK activation waves and facilitates cell invasion
○Sayuki Hirano1, Yohei Kondo1, Naoto Ueno2,3, Kazuhiro Aoki1,2,3 (1. Kyoto Univ., 2. Int. Res. Collab. Ctr. (IRCC), Natl. Insts. of Nat. Scis. (NINS), 3. Natl. Inst. for Bas. Biol. (NIBB), Natl. Insts. of Nat. Scis. (NINS))
[2P-398]Histone modifications involved in the regulation of mesenchymal stem cell differentiation dependent on mechanosensor protein vinculin
○Akihisa Ogawa1, Moe Fujiwara1, Yasuhisa Kimura1, Noriyuki Kioka1, Mito Kuroda1 (1. Kyoto University)
[2P-399]Discovery of a low-affinity LFA1-dependent signaling pathway mediated by the Rabin8-Rab8 axis
○Naoyuki Kondo1, Yoshihiro Ueda1, Tatsuo Kinashi1 (1. Kansai Med. Univ.)
[2P-400]Molecular Mechanism of Intestinal Barrier Dysfunction and Reconstitution via Labile Heme
○Daisuke Tsuji1, Mayu Hamada1, Reiko Akagi1 (1. Yasuda Women’s University)
[2P-401]Analyses of novel pathological mechanisms in in vitro models of human endometriosis
○Miona Jin1,2, Takumi Konno1,3, Arisa Kura1,2, Kimihito Saitou1,2, Tsuyoshi Saitou1,2, Takayuki Kohno1,3, Takashi Kojima1,3 (1. Sapporo Medical University, 2. Dept.of Obsterics and Gynecology, 3. Department of Cell Science, Institute of Cancer Research)
[2P-402]HMGB1 and syntaxins as regulatory elements of Tight Junction formation in epidermal keratinocytes
○Hiroko Matsunaga1, Yohei Hirai1 (1. Kwansei Gakuin univ. School of biological and environmental science, Dept. Biomedical science)
[2P-403]Extracellular pressure induces membrane blebs driving avian primordial germ cell migration
○Manami Morimoto1, Junichi Ikenouchi1,2, Yuji Atsuta1,2, Yoshiki Hayashi1,2, Daisuke Saito1,2 (1. Graduate School of System Life Science, Kyushu University, 2. Faculty of Science, Kyushu University)
[2P-405]Gap junction protein alpha 1-derived effects against brain microglia differ among cell types including neurovascular unit
○Akiko Doi1, Shuji Kubo1, Emiko Sonoda1, Akihiko Taguchi2, Takayuki Nakagomi1 (1. Hyogo Medical University, 2. Foundation for Biomedical Research and Innovation)
[2P-406]Effect of Cl– on migration ability in human prostate cancer cell lines PC-3 and LNCaP
○Miharu Katai1, Hiroaki Miyazaki1 (1. Setsunan University,Graduate School of Science and Engineering,Division of Life Science)
[2P-407]CAPN15, a ubiquitin-directed calpain protease, regulates E-cadherin mediated cell adhesion
○Aya Noguchi1, Shoji Hata1, Hikaru Tuchiya2, Hiroshi Shitara3, Yasushi Saeki4, Yasuko Ono1 (1. TMiMS. Calpain PJ, 2. Juntendo Univ., 3. TMiMS. , 4. Tokyo Univ.)
[2P-408]Solubilized-eggshell membrane promotes decorin secretion in human lung fibroblasts and attenuates TGF-β-induced fibrosis signal.
○Hiroki Hiruta1,2, Eri Ohto-Fujita2,3, Miho Shimizu2, Yukio Hasebe4, Yoriko Atomi2 (1. Dept. of applie. chem., Grad. Sch. of Eng., Univ. of Tokyo A&T, 2. Advanced Comprehensive Research Organization, Teikyo Univ., 3. Fac. Med. Tech., Teikyo univ., 4. Almado Inc.)
[2P-409]Epithelial cell-cell adhesion regulated by the I-BAR protein flow toward the membrane
○Tamako Nishimura1, Shiro Suetsugu1 (1. NAIST)
[2P-410]Complex structural analysis of ARHGAP25 and Septin2 to elucidate their binding domain using molecular dynamics simulation
○Tomoki Noguchi1, Syunsuke Sato2, Mamiko Mori4, Koji Saito4, Go Watanabe3 (1. Grad. Sch. of Front. Eng., 2. Grad. Sch. of Sci., Kitasato Univ., 3. Sch. of Front. Eng., 4. Sch. of Sci., Kitasato Univ.)
[2P-411]Distinct roles of TGF-β and Slug in the establishment of epithelial collective migration
○Tomoaki Nagai1, Hirokazu Kaji2, Michiru Nishita1 (1. Fukushima Medical University School of Medicine, 2. Tokyo Medical and Dental University)
[2P-412]A novel function of extracellular vesicles that regulates cell morphology through phenotypic synchronization
○Satoshi Otsuka1, Tomohiro Minakawa1, Jun K Yamashita1 (1. Department of Cellular and Tissue Communications, Graduate School of Medicine, The University of Tokyo)
[2P-413]C-type lectin-like receptor CD302 is essential in adhesion, migration, and differentiation of osteoblasts.
○Eriko Aoyama1,2, Satoshi Kubota2,1, Masaharu Takigawa1 (1. ARCOCS, Dental School/ Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2. Department of Biochemistry and Molecular Dentistry, Okayama University, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University)
[2P-414]Reguratory mechanism of actin cytoskeleton by Rho-Formin in yeast intracellular vesicle transport
○Kanako Kudo1, shinngai hajime, makoto nagano2, junko Toshima3, jiro toshima1 (1. tokyo university of science, 2. national institute of infectious diseases , 3. tokyo university of techonology)
[2P-415]Influence of Mg2+ ions on gene transfer using electrical short-circuiting via an aqueous droplet in dielectric oil
○Shun Tateishi1, Yuki Watanabe1, Rika Numano1, Hirofumi Kurita1 (1. Toyohashi University of Technology)
[2P-416]Efficient Generation of Induced pluripotent stem cells using a Droplet Electroporation Device
○Runa Ota1, Hirofumi Kurita1, Kojiro Matsumoto3, Rika Numano1,2 (1. Toyohashi University of Technology, Department of Applied Chemistry and Life Science,, 2. Toyohashi University of Technology, Institute for Research on Next-Generation Semiconductor and Sensing Science, 3. Nepa Gene Co., Ltd.)
[2P-417]Flow-through typed gene transfer equipment with low voltage alternative current application
○Miho Ishii-Teshima1,2, Koki Maeda1, Kenji Nakashima3, Rika Numano1, Hirofumi Kurita1, Takayuki Shibata1 (1. Toyohashi University of Technology, 2. JSPS research fellow RPD, 3. National Institute of Technology (Kosen), Sasebo College)
[2P-418]Imaging analysis of membrane traffic factors PATROL1 and SH3P3 that regulate stomatal movements
○Manami Ichita1, Koh Iba2, Katoh Kaoru3, Toutai Mitsuyama4, Takumi Higaki1 (1. Kumamoto Univ., 2. Kyushu Univ., 3. AIST BMRI, 4. AIST AIRC)
[2P-419]Investigation of microtube repair activity of MTCL1
○Kentaro Ito1, Atsushi Suzuki1 (1. Graduate School of Medical Life Science, Yokohama City University)
[2P-420]In vitro arginylation of beta-actin and its functional analysis
○Tomoki Muto1, Kodai Machida1, Hiroaki Imataka1, Mayumi Sunagawa1, Kentaro Noi2 (1. Department of Applied Chemistry, Graduate school of Engineering, University of Hyogo, 2. Engineering Biology Research Center Kobe University)
[2P-421]Changes in cold tolerance of mouse hippocampal primary cells during the early postnatal period
○Nobutoshi Ota1, Yuichi Saito1, Wataru Kimura1 (1. RIKEN)
[2P-422(2MS-02-05)]Molecular mechanism of SARS-CoV-2 transmission to blood vessels
○Yukino Ogura1, Yui Esumi2, Atsushi Kawaguchi1 (1. Institute of Medicine, University of Tsukuba, 2. School of Medicine and Health Science, University of Tsukuba)
[2P-423]Study on microtubule-lacking cells produced by dominant negative inhibition of a tubulin chaperone
○Hana Morii1, Hiroyuki Eguchi1, Atsushi Suzuki1 (1. Graduate School of Medical Life Science, Yokohama City University)
[2P-424]Identification of the protein motifs in type I myosins dictating chirality from cell to organ in Drosophila
○Asuka Yamaguchi1, Takeshi Sasamura1, Kohei Yoshimura2, Takeshi Haraguchi2, Chinami Maeda1, Koji Ito2, Kenji Matsuno1 (1. Graduate school of science, Osaka University, 2. Graduate school of science, Chiba University)
[2P-425]Regulation of mechanical stress responses in T-tubule-like structures by membrane remodelling molecules
○Tetsuya Takeda1, Kenshiro Fujise1,2, Satoru Noguchi3, Ichizo Nishino3, Kohji Takei1 (1. Okayama University, 2. Yale University School of Medicine, 3. NCNP)
[2P-426]Visualization of intracellular structures in growth cones using fluorescence shadow imaging
○Motohiro Nozumi1, Michihiro Igarashi1 (1. Department of Neurochemistry and Molecular Cell Biology, School of Medicine and Graduate School of Medical/Dental Sciences, Niigata University, Niigata, Japan)
[2P-427]Functions of N-linked glycans of multi-drug transporter ABCG2 derived from mouse and human.
○Tomoe Tanaka1, Shun Hiromori2, Hiroki Nagami2, Gen Kimura2, Hiroto Sugiura2, Makito Sumimoto2, Yoshitomo Taguchi1,2 (1. Div. of Biotechnol. Sci., Grad. Sch. of Kindai Univ., 2. Div. of Genet. Eng., Kindai Univ.)
[2P-428]Species Specific Inactivation of TRPC Channels and its potential role to Renal Desease Phenotypes
○Ryu Nonaka1,2, Reiko Sakaguchi2, Takanori Kihara1, Masayuki X Mori2 (1. The University of Kitakyusyu, 2. University of Occupational and Environmental Health)
[2P-429]Analysis of sperm-cell-surrounding membrane breakdown upon pollen tube discharge in Arabidopsis
○Naoya Sugi1, Daichi Susaki1, Kazuo Ebine2,3, Hidenori Takeuchi4,5, Shiori Nagahara6, Tetsu Kinoshita1, Thomas Widiez7, Daisuke Maruyama1 (1. KIBR, Yokohama City Univ., 2. Div. Cellular Dynamics, NIBB, 3. SOKENDAI, 4. ITbM, Nagoya Univ., 5. IAR, Nagoya Univ., 6. GSSci, Kyoto Univ., 7. Univ. Lyon, ENS de Lyon, UCB Lyon, CNRS, INRAE)
[2P-430]BubR1 is required for midgut remodeling in Drosophila diapause
○Yuya Adachi1, Hiroki Nagai2, Masayuki Miura1, Yuichiro Nakajima1 (1. Graduate School of Pharmaceutical Sciences, University of Tokyo, 2. Institute of Science and Technology Austria)
[2P-431]Stratification of high-risk HPVs by E6-associated chromosomal abnormalities
○Kanako Hori1,2, Nanami Seshimo, Ryusuke Nozawa1, Toru Hirota1 (1. Japanese Foundation for Cancer Research, 2. Tokyo University of science)
[2P-432]Biological significance and mechanism of nucleolar accumulation of cyclin-dependent kinase in fission yeast
○Risa Yoshioka1, Mizuki Terauchi1, Hirai Hayato2, Sen Yuki3, Ota Kunihiro2, Yamamoto Ayumu1 (1. Grad. Sch. Int. Sci. Tech., Shizuoka Univ., 2. Dept. Life Sci. Grad. Sch. Art. Sci., Tokyo Univ. , 3. Dept. Integ. Sci. Coll. Art. Sci., Tokyo Univ.)
[2P-433]Impact of Karyotypic Evolution on Growth Advantage
○Shengyue Lei1,2, Minji Jo1, Utako Kato1, Toru Hirota1,2 (1. Div. Exp. Pathol., Cancer Inst., JFCR, 2. Dept. JFCR., Tokyo Med. & Dent. Univ.)
[2P-434]Microarray chip for individual cell culture using UVC light
○Hidetaka Ueno1,2,3, Shohei Yamamura3 (1. Kobe University, Center for Advanced Medical Engineering Research & Development, 2. Kobe University, Graduate School of Medicine, 3. National Institute of Advanced Industrial Science and Technology, Health and Medical Research Institute)
[2P-435]The identification of ATPAF1 as a putative aneuploidy sensor
○Xiaoai Lyu1,2, Jungseog Kang1 (1. New York University Shanghai , 2. New York University)
[2P-436]A novel protein kinase NRK possibly contributes to cellular homeostasis by regulating lysosomal function
○Kimitoshi Denda1, Toshiaki Fukushima1,2, Beni Lestari1, Masayuki Komada1,2, Nobuhiro Hayashi1, Yoshihisa Matsumoto2, Mikio Shimada2 (1. Institute of Science Tokyo, School of Life Science and Technology, 2. Institute of Science Tokyo, Institute of Innovative Research)
[2P-437]Timely spindle bipolarization suppresses incorrect kinetochore-microtubule attachment during meiosis I in mouse oocyte
○Shuhei Yoshida Yoshida1, Tomoya S Kitajima1 (1. RIKEN)
[2P-438]Observing Microtubule Dynamics Using High-Speed Atomic Force Microscopy(HS-AFM)
○Yoshiki Higashiguchi1, Shuyu Li 2, Elma Sakinatus Sajidah1, Keesiang Lim3, Tomoyuki U Tanaka2, Richard W Wong3 (1. Nano life science Kanazawa Univ. , 2. Divisio of Molecular, Cell and Developmental Biology, School of Life Science Dundee Univ. , 3. WPI NanoLSI Kanazawa Univ.)
[2P-439]Development of a genetically encoded biosensor for epidermal growth factor and quantification of dissociation constant of cyclin and CDK complex
○Aika Toyama1,2,3,4, Yuhei Goto1,2,3,4, Emi Ebine3, Yohei Kondo1,2,3,4, Kazuhiro Aoki1,2,3,4 (1. SOKENDAI, Basic Biology Program, 2. ExCELLS, 3. NIBB, 4. Kyoto Univ., Grad School of Biostudies)
[2P-440]Network Structural Theory Unveils Independent Regulation of Multiple Cell Cycle Checkpoints and a Novel M cyclin Degradation Pathway in the Fission Yeast
○Yuhei Yamauchi1, Hironori Sugiyama2, Yuhei Goto3, Kazuhiro Aoki3, Atsushi Mochizuki1 (1. Institute for Life and Medical Sciences, Kyoto University, 2. School of Engineering, The University of Tokyo, 3. Graduate School of Biostudies, Kyoto University)
[2P-441]Cultivation of human skin cells using the recombinant Bombyx mori sericin including epidermal growth factor
○Junko Matsumoto1, Keiko Takaki1, Eiji Kotani1 (1. Kyoto Institute of Technology, Graduate School of Science and Technology, Department of Applied Biology, Laboratory of Insect Engineering)
[2P-442]The effects of flavonoid metabolites on immune response in mesenteric lymph nodes
○RISA YANAGI1, Nao Ishizaki1, Sana Shinomiya2, Kaeko Murota2, Haruko Hayasaka3 (1. Dept. Life Sci., Grad. Sch. Sci. and Eng., Kindai Univ., 2. Dept. Life Sci., Grad. Sch. Nat. Sci. and Tech., Shimane Univ., 3. Res. Inst. Sci. and Tech., Kindai Univ.)
[2P-443]Knockdown of ERRα represses cell proliferation and induces apoptosis in human skin fibroblasts
○Naoki Nanashima1, Toshio Norikura1, Manabu Nakano2, Chie Hata3, Kayo Horie2 (1. Aomori University of Health and Welfare, 2. Hirosaki Univ., 3. Kyoto Univ.)
[2P-444]Centrosome protein CEP169 positively regulates cell proliferation via the Ras-MAPK pathway
○Shunsuke Imai1, Yusuke Mori1, Miyuki Shintomi1, Yusuke Akatani1, Kosuke Kinoshita1, Shogo Kuramochi1, Yasuhiko Terada1 (1. Dept. of Chem. and Biochem., Grad. Sch. of Adv. Sci. and Eng., Waseda Univ.)
[2P-445]The CRISPR screening reveals a molecular network which ensures proper mitotic progression
○JIAHANG MIAO1, Masatoshi Hara1, Keys R. Heather2, Weixia Kong1, Kuan-Chung Su2, Cheeseman M. Iain2, Tatsuo Fukagawa1 (1. Osaka Univ., 2. MIT)
[2P-446]Cell senescence phenotype in cancer cell lines
○Hiroaki Kuribayashi1,2, Satoshi Kawakami1, Teh-Wei Wang1, Makoto Nakanishi1 (1. Div. of Cancer Cell Biol., Inst. of Med. Sci., Univ. of Tokyo, 2. Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo)
[2P-447]Cellular response induced by low-temperature atmospheric pressure plasma
○Katsuki Jozuka1,2,3, Shinji Yoshimura4,5 (1. Astrobiology Center, NINS, 2. National Institute for Basic Biology, NINS, 3. SOKENDAI, 4. National Institute for Fusion Science, NINS, 5. Center for Low-temperature Plasma Science, Nagoya Univ.)
[2P-448]Effects of myokines derived from clutured myoblasts on adipocytes
○Reiki Iwaya1, Chihiro Tomituka1, Yuji Takeda2, Shinichi Saitoh2, Hironobu Asao2, Hidetoshi Nara1 (1. Isinimai Senshu University, 2. Yamagata University)
[2P-449]Analysis of the mechanism regulating Mps1 by Chk1 in cancer cells under the heat stress
○Kentaro Oya1 (1. Graduate School of Tokyo Univ of Agriculture)
[2P-450]Elucidating the Significance of PP2A Methylation by Separating the Functions of PME-1 as a PP2A Methylesterase and a PPI-mediated PP2A Inhibitory Protein
○Takashi Ohama1 (1. Yamaguchi University)
[2P-451]CHK1 promotes the association between the tumor suppressor PP2A and its inhibitory protein PME-1
○Sana Ando1, Keiko Tanaka2, Maharu Matsumoto2, Yuki Oyama2, Koichi Sato1,2, Takashi Ohama1,2 (1. Joint Graduate School of Veterinary Medicine, Yamaguchi University, 2. Joint Faculty of Veterinary Medicine, Yamaguchi University)
[2P-452]MAP kinase phosphatase MKP-1 promotes age-dependent morphological changes of neurons in C. elegans
○Takafumi Nomachi1, Kunihiro Matsumoto1, Naoki Hisamoto1 (1. Div. of Bio. Sci., Grad. School of Sci., Nagoya Univ.)
[2P-453]Membrane protein synthesis and protein-protein interaction analysis using AirID and wheat cell-free nanodisc method.
○Sara Yoshii1, Kohdai Yamada1, Keiichiro Kami2, Ryo Morishita2, Kohei Nishino3, Hidetaka Kosako3, Tatsuya Sawasaki1 (1. Ehime Univ., 2. CellFree Sciences Co., Ltd. Research and Development Dept., 3. IAMS. Tokushima Univ.)
[2P-454]Polyamines control the amount of ISG15 modification
○Fumihiko Okumura1, Haruka Etori1 (1. Fukuoka Women's Univ.)
[2P-455]Cancer malignant progression via non-canonical activation of receptor tyrosine kinase EphA2
○Yue Zhou1, Ryota Oki1, Akihiro Tanaka1, Naru Hamada1, Satoru Yokoyama1, Hiroaki Sakurai1 (1. Cancer Cell Biol., Univ. of Toyama)
[2P-456]Analysis of the mechanism of TORC1 repression by fission yeast lifespan regulator, Ecl1
○Sawa Kawai1, Hokuto Ohtsuka1, Yurika Ito1, Yoko Otsubo2, Takafumi Shimasaki1, Akira Yamashita3, Hirofumi Aiba1 (1. Graduate School oh Pharmaceutical Sciences, Nagoya University, 2. The University of Tokyo, 3. Graduate School of Arts and Sciences, The University of Tokyo)
[2P-457]Identification of GGCX-mediated carboxylation of intracellular proteins and their possible functions in stress responses
○Keiji Nozaki1, Tomohiko Okazaki2, Hidetaka Kosako3, Yukiko Gotoh1,4 (1. Grad. Sch. of Pharm. Sci., The Univ. of Tokyo, 2. Inst. of Genet. Med., Hokkaido Univ., 3. Inst. of Adv. Med. Sci., Tokushima Univ., 4. IRCN, Univ. Tokyo)
[2P-458]The mechanism of targeted protein degradation through the branched ubiquitin code
○Fumiaki Ohtake1, Yuki Mori1, Yoshino Akizuki1, Rikuto Honda1, Mai Morita1 (1. Hoshi University)
[2P-459]Identification of Substrate of The Sck1 Kinase that Control High-Temperature Growth in fission yeast
○Taisuke Naka1, Yuichi Morozumi1, Daisuke Watanabe1, Kazuhiro Shiozaki1,2 (1. Nara Institute of Science and Technology, 2. University of California, Davis)
[2P-460]Elucidating the mechanism underlying nutrient-dependent AKT signaling dynamics
○Lay Nurhana Sari1, Shun Masuda1, Takafumi Miyamoto1 (1. University of Tsukuba)
[2P-461]Osmotic enhancement of the MAP3Ks-MAP2K reaction in the yeast stress-responsive MAPK pathway
○Kazuo Tatebayashi1, Haruo Saito1 (1. The University of Tokyo)
[2P-462]Isorhamnetin alleviates renal fibrosis by inducing endogenous hydrogen sulfide and regulating thiol-based redox state in obstructed kidneys
○zhen zhang1, Yan Hai Zhang1, Yu Jian Shi1, Jian Yao2 (1. Shaanxi University of Chinese Medicine, 2. University of Yamanashi)
[2P-463]Identification of phosphorylation-dependent dimerization mechanism of arginine methyltransferase Hmt1
○Miyabi Endo1, Takunori Yasuda2, Rikuri Morita3, Tomoaki Mizuno4, Kenji Irie4, Ryuhei Harada3 (1. Ph.D. Program in Human Biology, Graduate School of Comprehensive Human Science, University of Tsukuba, 2. Doctoral Program in Biology, Graduate School of Science and Technology, University of Tsukuba, 3. Center for Computer Sciences, University of Tsukuba, 4. Molecular Cell biology, Medicine, University of Tsukuba)
[2P-464]TC10 GTPase contributes to efficient axon regeneration not only by promoting regrowth of proximal axons but also by facilitating Wallerian degeneration in distal axons
○Suzuka Akiyama1, Shingo Koinuma1, Misa Miyaji1, Naoyuki Wada2, Michihiro Igarashi3, Takeshi Nakamura1 (1. Grad. Sch. of Biol. Sci., Tokyo Univ. Sci., 2. Grad. Sch. of Sci. and Tech., Tokyo Univ. Sci., 3. Grad. Sch. Med. and Dental Sci., Niigata Univ.)
[2P-465]Light and circadian clock-dependent transcriptional regulation by the two-component regulatory system in cyanobacteria
Akira Yasuda1, Kotone Saito1, Kae Hasegawa1, ○Mitsumasa Hanaoka1,2,3 (1. Grad. Sch. Horticul, Chiba Univ., 2. Plant Mol. Sci. Cent., Chiba Univ., 3. Space Agr. Hort. Cent., Chiba Univ.)
[2P-466]Kinase isoform-specific artificial substrate peptides: design and experimental verification
○Saki Toi1, Junqi Liang1, Junna Nakazono1, Dai Sakamoto1, Naoyuki Sugiyama1,2, Yasushi Ishihama1,3 (1. Grad. Sch. Pharm.Sci., Kyoto Univ., 2. NCVC, 3. NIBIOHN)
[2P-467]Regulation of SAPK signaling and cell fate decisions in genotoxic stress response
○Shuri Komai1,2, Yukari Shiozaki1, Yuji Kubota1, Mutsuhiro Takekawa1,2 (1. Division of Cell Signaling and Molecular Medicine, Institute of Medical Science, The University of Tokyo, 2. Department of Biological Sciences, Graduate School of Science, The University of Tokyo)
[2P-468]The regulatory mechanism of deubiquitinating enzyme USP8 activation and its dysregulation by cancer-related mutations
○Yusuke Takehara1, Keijun Kakihara2, Masayuki Komada1,2, Toshiaki Fukushima1,2 (1. School of Life Science and Technology, Institute of Science Tokyo, 2. Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo)
[2P-469]Elucidation of a novel regulatory mechanism of the cell death-inducing droplets by NBR1
○Wakana Suzuki1, Shuhei Hamano1, Yusuke Hirata1, Takuya Noguchi1, Atsushi Matsuzawa1 (1. Lab. of Health Chem., Grad. Sch. of Pharmaceut. Sci., Tohoku Univ.)
[2P-470]Analysis of the function of Sec16A in the mTORC1 pathway
○Yuichiro Ioi1, Misaki Kobayashi1, Chiaki Ishii1, Masatoshi Maki1, Hideki Shibata1, Terunao Takahara1 (1. Dept. of Applied Biosci., Grad. Sch. of Bioagric. Sci., Nagoya Univ.)
[2P-471]Camphorquinone’s role in alleviating Non-Alcoholic Fatty Liver Disease via SIRT1/LKB1/AMPK pathway activation
○Kil Hwan Kim1, Nagarajan Maharajan2, Karthikeyan A Vijayakumar3, Gwang Won Cho3 (1. Veterans Health Service Medical Center, Korea, 2. University of Maryland School of Medicine, USA, 3. Chosun University, Korea)
[2P-472]Exploring atmospheric microorganisms that affect CCR7 signaling
○Kanata Sugimoto1, Tomoka Katayama2, Daiji Okamura2,3, Teruya Maki1,4, Haruko Hayasaka1,4,5 (1. Dept Sci., Grad. Sch. Sci. Eng., Kindai Univ., 2. Dept. Adv. Bio., Grad. Sch. Agr., Kindai Univ., 3. Dept. Adv. Bio., Grad. Sch. Agr., Kindai Univ, 4. Dept. Life Sci., Fac. Sci. Eng., Kindai Univ., 5. Res. Inst. Sci. and Tech., Kindai Univ.)
[2P-473]Taurine promotes glucagon-like peptide-1 secretion from enteroendocrine L cells
○Yuri Osuga1, Kazuki Harada1, Takuya Yamauchi1, Tetsuya Kitaguchi2, Masami Hirai3, Mitsuharu Matsumoto4, Takashi Tsuboi1 (1. Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, 2. Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 3. RIKEN Center for Sustainable Resource Science, 4. Dairy Science and Technology Institute, Kyodo Milk Industry Co., Ltd.)
[2P-474]Elucidation of the molecular mechanism of the interaction between yki and Aminoacyl-tRNA synthetase
○Taito Fukunaga1, Nozomi Watanabe1, Keiichi Ideguchi1, Hideki Yoshida1 (1. Kyoto Institute of Technology)
[2P-475]Oxidative stress imaging analysis in mitochondrial disease iPS cells
○Kohei Homma1,2,3 (1. Kobe City Eye Hospital, 2. Fujita Health University, 3. Keio University)
[2P-476]Effect of Brain-Derived Neurotrophic Factor: BDNF on AMPA receptor dynamics
○Rie Kato1, Shigeo Sakuragi2, Hiroko Bannai2 (1. Dept. of Elec.Eng. Biosci.,Grad.Sch.of Adv.Sci.Eng.,Waseda Univ., 2. Fac. of Sci. Eng., Waseda Univ.)
[2P-477]Exploration of Anti-inflammatory Effects and Biomonitoring Methods Using Food Dyes for Extracellular Vesicles Derived from Lactococcus cremoris and Lactobacillus acidophilus
○Rinka Kizaki1, Hiroshi Takemori2 (1. Gifu Univ., 2. Gifu Univ. graduate school)
[2P-478]Effect of homocysteine on methylglyoxal metabolism in yeast
○Kosei Oie1, Kayo Ikeda1, Wataru Nomura2, Yoshiharu Inoue1 (1. Div. of Appl. Life Sci., Grad. Sch. of Agric., Kyoto Univ., 2. Grad Sch. of Agric., Shinshu Univ.)
[2P-479]Glossogyne tenuifolia modified T cell activation by inhibition of MAPK activity
○Li-Wen Fang1, Hsin-Jen Tsai1,2, Jer-Yiing Houng1 (1. Dept. of Nutr., I-Shou Univ., Kaohsiung, Taiwan., 2. Dept. of Health Manag., I-Shou Univ., Kaohsiung, Taiwan)
[2P-480]Bilateral regulation of EGFR activity and local PI dynamics observed with superresolution microscopy
○Mitsuhiro Abe1, Masataka Yanagawa2,1, Yasushi Sako1 (1. RIKEN, 2. Tohoku Univ.)
[2P-481(2AS-12-01)]Elucidation of the mechanism by which polysaccharides from southern Ulva Meridionalis recover reduced intestinal barrier function
○Yuka Maejima2, Takushi Namba1,2 (1. Research and Education Faculty, Multidisciplinary Science Cluster, Interdisciplinary Science Unit, Kochi Univ., 2. Faculty of Agriculture and Marine Science, Kochi Univ.)
[2P-482]Functional analysis of sphingomyelinase genes in Dictyostelium development
○Ayaka Ikeya1, Takaaki Narita2 (1. Graduate School of Advanced Engineering, Chiba Institute of Technology, 2. Department of Life Science, Faculty of Advanced Engineering, Chiba Institute of Technology)
[2P-483]Development of evaluation system for Kisspeptin 10 activity using mammalian cell display
○Keigo Hoshi1, Kosato Hamaoka1, Nin Ling1, Tetsuya Kadonosono1 (1. Tokyo Institute of Technology)
[2P-484]Fisetin targets IRF1 to attenuate IFN-γ-stimulated macrophages inflammation
○Ziyu He1, Xuchi Pan2, Kun Xie1, Kozue Sakao1,2, De-Xing Hou1,2 (1. Kagoshima Univ., 2. Agrifish. Kagoshima Univ.)
[2P-485]Intracellular signaling mechanisms in the activation of sperm motility regulation in Ciona intestinalis
○Ruka Kinoshita1, Kogiku Shiba2, Manabu Yoshida3, Kaoru Yoshida1 (1. Graduate School of Engineering, Toin University of Yokohama, 2. Institute of Life and Environmental Sciences, University of Tsukuba, 3. Graduate School of Science, The University of Tokyo)
[2P-486]Exploration of MSC Marker Molecules Associated with Angiogenesis and Migration in Vascular Endothelial Cells
○Haruka Sugiyama1, Tohru Sugawara2 (1. Yokohama City Univercity, 2. Graduate School of Medicial Life Science, Yokohama City Univercity)
[2P-487]Activation of caspase-9 by self-cleavage in unfertilized eggs of starfish
○Tomoko Yamashina1, Ayumi Takamizawa2, Hiroyuki Takeda3, Tatsuya Sawasaki4, Kazuyoshi Chiba1,2 (1. Dept. of Biol., Ochanomizu Univ., 2. Dept. of Biol. Sci., Ochanomizu Univ., 3. Division of Proteo-Drug-Discovery Sciences, PROS, Ehime Univ., 4. Division of Cell-Free Sciences, Proteo-Science Center, Ehime Univ.)
[2P-488]‘Mechano-gradients’ drive morphogen-noise correction to ensure robust patterning
○Kana Aoki1, Tohru Ishitani1 (1. RIMD, Osaka Uviv.)
[2P-489]Neuroprotective effect via alteration in mitochondrial membrane potential by KCC2 inhibitor.
○Yumi Hosaka1, Kana Omatsu1, Koichi Kawada1, Kyosuke Uno1, Nobuyuki Kuramoto1 (1. Setsunan University)
[2P-490]Memory effects by ionizing radiation-induced DNA damage and repair.
○Yasuko Honjo1 (1. Hiroshima University)
[2P-491]Identification of autophagy inducers within plasma-activated Ringer’s lactate solution
○Taishi Yamakawa1, Ayako Tanaka2, Camelia Miron2, Kae Nakamura2, Hiroaki Kajiyama2, Shinya Toyokuni2, Masaaki Mizuno2, Kenji Ishikawa2, Masaru Hori2, Hiromasa Tanaka2 (1. Nagoya Univ., 2. Center for Low-temperature Plasma Science, Nagoya Univ.)
[2P-492]Synthesis of fluorescently labeled sphingomyelin and elucidation of the pyroptosis activation mechanism
○Jumpei Ueno1, Xuhao Huang1, Masayuki Takamatsu1, Yoshifumi Matsuura1, Taketo Toda1, Shinya Hanashima2, Hirotaka Kanoh3, Atsushi Shimoyama1,5, Kazuya Kabayama4,1,5, Koichi Fukase1,4,5 (1. Grad. Sch. Sci., Osaka Univ., 2. Grad. Sch. Eng., Tottori Univ., 3. IAB, Keio Univ., 4. IRS, Osaka Univ., 5. FRC, Osaka Univ.)
[2P-493]Elucidation of the mechanism of neuropathy induced by adrenaline administration to neurons
○Kazuki KOZAKAI1, Tsai Cheng-Ta2,3, Chia Yuan Hsu3, Shion Osana4, Masaru Sakurai1,2,4, Masaki Kaneko3, Hideharu Tanaka1,2,4, Katsuhiko Hata1,2,4 (1. Kokushikan University Graduate School, 2. Graduate School of Physical Education, Kokushikan University, 3. Molecular Nutrition Institute, Inc., 4. Kokushikan University, Faculty of Physical Education, Department of Sports Medicine)
[2P-494]Possible function of PPAR γ in chondrocyte differentiation and apopsosis
○Risa Fugono1,2, Kazumi Kawata1, Masaharu Takigawa3, Hiroshi Kamioka2, Sasoshi Kubota1 (1. Okayama University Department of Biochemistry & Molecular Dentistry, 2. Okayama University Department of Orthodontics, 3. Okayama University ARCOCS)
[2P-495]Analyses of axon-mediated retrograde neuroprotection via an LRP1 in compartmented cultures
○Hideki Hayashi1, Hinami Sashi1, Yui Iwatani1, Yoshiyuki Moriyama1, Norio Takagi1 (1. Dept. of Appl. Biochem., Sch. of Pharm., Tokyo Univ. of Pharm. Life Sci.)
[2P-496]A genetic screen for upstream regulators of cell competition.
○Mai Sakaguchi1, Hiroshi Kanda1, Tomoe Kobayashi2, Makoto Matsuyama2, Keita Miyoshi3, Shu Kondo3,4, Kuniaki Saito3, Tatsushi Igaki1 (1. Department of Genetics, Graduate School of Biostudies, Kyoto University, 2. Division of Molecular Genetics, Shigei Medical Research Institute, 3. Invertebrate Genetics Laboratory, Department of Chromosome Science, National, 4. Department of Biological Science and Technology, Tokyo University of Science)
[2P-497]G2A is involved in metabolic adaptation and resistance to carbonyl stress in glucose-induced cancer cells
○Md Abul Hassan1, Hidetaka Shimizu2, Okazune Minagawa2, Takato Oue2, Yuiri Hirata2, Qin Simao2, Takahito Fukui2, Koji Kishimoto3 (1. Faculty of Bioscience and Bioindustry, Tokushima University Graduate School of Advanced Technology and Science, Tokushima, Japan, 2. Faculty of Bioresource Science, Tokushima University Graduate School of Sciences and Technology for Innovation, Tokushima, Japan, 3. Division of Bioscience and Bioindustry, Tokushima University Graduate School of Technology, Industrial and Social Sciences, Tokushima, Japan)
[2P-498]A novel type of physiological necrosis during embryogenesis in mouse brain
○TAIBO LI1,2, Shigeki HIGASHIYAMA2, Yoshihide TSUJIMOTO3, Yusuke IMAGAWA1,2 (1. Osaka Univ., Grad. Sch. of Pharm. Sci., 2. Osaka Intl. Cancer Inst., Res. Ctr., Dept. of Oncog. Growth Regul., 3. Osaka Intl. Cancer Inst., Res. Ctr.)
[2P-499]Elucidation of the mechanism inducing spoptosis, a new cell death mode
○Rikako Yamamoto1, Ko Eto1 (1. Dept. Biol. Sci., Fac. Sci., Kumamoto Univ.)
[2P-500]Protective effects of GM1 ganglioside in NLRP3 inflammasome activation and pyroptosis in microglial cells
○Yuan-Shieh Huang1, Yung-Chun Shih1, Ting-Yin Yeh1 (1. Department of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan)
[2P-501]Genetic dissection of the molecular mechanism of cell competition triggered by tricellular junction disruption
○Kiyora Nishikawa1, Yoriko Kawasaki1, Haolin Xie1, Kiichiro Taniguchi1, Tatsushi Igaki1 (1. Tatsushi Igaki’s lab at Kyoto University, Japan)
[2P-502]The ionic liquid-assisted sample preparation method pTRUST allows sensitive proteome characterization of a variety of bacterial endospores to aid in the search for potential protein biomarkers
○Tohru Ichimura1, Masato Taoka2, Ritsuko Kuwana3, Hiromu Takamatsu3 (1. National Defense Academy, JAPAN, 2. Tokyo Metropolitan University, 3. Setsunan University)
[2P-503]Identification of Bacillus subtilis spore proteins using a combination of sensitive proteomic analysis with fluorescence microscope observation of GFP fusion proteins
Ritsuko Kuwana1, Masato Taoka3, Tohru Ichimura2, ○Hiromu Takamatsu1 (1. Setsunan Univ., 2. National Defense Academy, 3. Tokyo Metropolitan Univ.)
[2P-504]Analysis of the localization sites of nucleic acid binding proteins in Bacillus subtilis.
○Miku Hashiguchi1, Kikyo Toyoki1, Ritsuko Kuwana1, Kiyoshi Ito1, Hiromu Takamatsu1 (1. Setsunan Univ.)
[2P-505]Analysis of membrane protein localization in the vegetative cells and spores of Bacillus subtilis.
○Kikyo Toyoki1, Miku Hashiguchi1, Ritsuko Kuwana1, Kiyoshi Ito1, Hiromu Takamatsu1 (1. Setsunan Univ.)
[2P-506]SpoIVA is an essential morphogenetic protein for the formation of heat- and lysozyme-resistant spores in Clostridium sporogenes NBRC 14293
○Ritsuko Kuwana1, Bruno Dupuy2, Isabelle Martin-Verstraete2, Hiromu Takamatsu1 (1. Setsunan University, 2. Institut Pasteur)
[2P-507]In vivo analysis of mechanoresponse in live bone endothelial cells using two-photon microscopy
○Kazumasa Nishino1, Hina Takegami1, Akinori Hatano1, Takanobu Fukunaga2, Masamichi Yamamoto3, Keizo Nishikawa1 (1. Dept. of Med. Life Sys., Grad. Sch. of Biomed., Univ. of Doshisha, 2. Fac. of Eng., Univ. of Kyushu, 3. NCVC)
[2P-508]Intracellular dynamics of chiral actin fibers induced by type I myosins during cell chirality formation
○Haruna Nishikawa1, Daiki Kitamura1, Mikiko Inaki1, Kenji Matsuno1 (1. Osaka University)
[2P-509]One-cell quantitative analysis of Escherichia coli signaling to the removal of the attractant serine
○Shunta Esaki1, Akihiko Ishijima1, Hajime Fukuoka1, Yumiko Uchida1 (1. Graduate School of Frontier Biosciences Osaka University)
[2P-510]Measurement of changes in potassium ion concentration in neurons using a simple ion meter
○Airi Nishi1, Takaya Iwamoto1, Ryuta Morinaga1, Koichi Kawada2, Kyosuke Uno2, Nobuyuki Kuramoto2 (1. Setsunan univ., 2. Yobouyakurigaku Pharm.)
[2P-511]Immuno-Assay Using Cell-based Giant Magneto-Resistive Sensor
○Chihiro Manri1, Masayoshi Momiyama2, Toshiro Saito3, Naoshi Itabashi3, Takashi Nakasawa4 (1. Healthcare Innovation Center, R&D Group, Hitachi Ltd., 2. Sales & Marketing Div., Hitachi High-Tech Corporation, 3. Naka Diagnostic Products Div., Hitachi High-Tech Corporation, 4. Healthcare Business Strategy Planning Div., Hitachi High-Tech Corporation)
[2P-512]The effects of PS-MPs on oxidative damage via Nrf-2 signalling pathway in liver cells
○Mengchao Ying1,2, Xinyu Hong1,2, Ping Xiao1,2, Gonghua Tao1,2 (1. Shanghai Municipal Center for Disease Control and Prevention, 2. State Environmental Protection Key Laboratory of Environmental Health Impact Assessment of Emerging Contaminants)
[2P-513]The mechanism regulating behavior in Haemaphysalis longicornis by Haller’s organ
○Kayoko Yamaji1,2, Hirotaka Kanuka1,2 (1. Dept. Trop. Med., Jikei Univ. Sch. Med., 2. Cent. Med. Entomol., Jikei Univ. Sch. Med.)
[2P-514]Development of enzyme free cell detachment method using ultrasonic vibration to maintain extracellular and cell membrane proteins -Application to Mesenchymal stem cells
○Hideharu Shimozawa1, Shinsuke Mochizuki1, Fumiko Tomatsu1, Chikahiro Imashiro2,3, Jun Homma3, Yoshikatsu Akiyama3, Yuji Haraguchi3, Tatsuya Shimizu3 (1. Canon Inc., 2. Univ. of Tokyo, 3. Inst. of Adv. Biomed. Eng., Univ. of Tokyo Women’s Medical)
[2P-515]Attempts to generate Hyaluronic acid (HA) derivatives with novel functions
○Kotono Mashiba1, Yohei Hirai1, Suzuka Matsushita1 (1. Dept. biomedical, Sch. Sci. Technol., Kwansei Gakuin University)
[2P-516]Influence of positively charged nanobubbles to neurons
○Yifan Liu1, Takeshi Ohdaira2, Emi Kitakata2, Yoshihisa Harada2, Kumiko Hayashi2 (1. Graduate School of Fronteir Science, The University of Tokyo, 2. The Institute for Solid State Physics, The University of Tokyo)
[2P-517]Fabrication and Evaluation of Composite Hydrogel Scaffold Based on Silk Fibroin / Phosphorylated Chitin / Chitosan
○Yushi Kusano1, Takaomi Nomura1, Shota Nakano1 (1. Shinshu university)
[2P-518]Verification of mechano-bactericidal effect of aragonite nanoneedles on Bacillus subtilis in water
○Yuuki Shibano1, Satoshi Toba1, Naoki Nemoto1, Nobuaki Negishi2 (1. Dept. of life Sci., Grad. Sch. of Adv. Eng., Chiba Ins. of Tec., 2. National Institute of Advanced Industrial Science and Technology)
[2P-519]Fabrication and evaluation of phosphorylated chitin/chitosan composite sponge scaffold
○Shota Nakano1, Yushi Kusano1, Takaomi Nomura1 (1. Div. Appl. Biol., Dept. Tex. Sci. Tech., Shinshu Univ.)
[2P-520]Optimization of red fluorescent protein vectors in Staphylococcus aureus
○Fuminori Kato1 (1. Hiroshima Univ.)
[2P-521]Analysis of temperature tolerance mechanisms using primary cultured cells of Buergeria frogs
○Hinayo Ogino1,2, Hajime Ogino1,2, Makoto Suzuki1,2, Takeshi Igawa1,2 (1. Grad. Sch. of Integrated Science for Life, Hiroshima Univ., 2. Amphibian Research Center, Hiroshima Univ.)
[2P-522]The effect of rosmarinic acid on MUC5AC and MUC5B production in vivo and in vitro
○Jun Iwashita1 (1. Akita prefectural university)
[2P-523]Sex difference analysis of cell competition in mouse pancreas
○Yuta Sakae1, HeeWon Seo1, Shunsuke Kon1 (1. Tokyo University of Science)
[2P-524]Molecular Basis of Hypoxia Resistance Acquired by Exposure to the Hepatotoxin Microcystin-LR
○Yasunari Yunoki1, Risa Eto1, Shota Takumi1,2, Kazuhiro Shiozaki1,2, Masaharu Komatsu1,2 (1. Graduate School of Agriculture, Forestry and Fisheries, Kagoshima University, 2. The United Graduate School of Agricultural Sciences, Kagoshima University)
[2P-525]Attenuation Effect of Rutin on the Cytotoxicity of Hepatotoxin Microcystin-LR
○Risa Eto1, Yasunari Yunoki1, Kazuhiro Shiozaki1,2, Shota Takumi1,2, Masaharu Komatsu1,2 (1. Graduate School of Agriculture, Forestry and Fisheries, Kagoshima University, 2. The United Graduate School of Agricultural Sciences Kagoshima University)
[2P-526]Creation of a unique Tumor environment through interactions between Giant nucleated cancer cells and fibroblasts
○Go Itoh1, Masamitsu Tanaka1 (1. Akita University Graduate School)
[2P-527]Development of a culture method for lymphocytes of tiger sharks.
○Yuki Nitta1,2, Wataru Takagi3, Susumu Hyodo3, Masahiro Yasunaga1,2 (1. The University of Tokyo, 2. Div. Development Therap., EPOC, Natl Cancer Ctr., 3. Atmosphere and Ocean Research Institute,The University of Tokyo)
[2P-528]Biodegradability and characterization of biodegradable plastic-degrading bacteria
○Hajime Morimoto1,2, Suno Nishiyama1 (1. komham inc., 2. Ritsumeikan University)