Session Details
[3P-1]Poster Presentation
Fri. Nov 29, 2024 12:55 PM - 2:55 PM JST
Fri. Nov 29, 2024 3:55 AM - 5:55 AM UTC
Fri. Nov 29, 2024 3:55 AM - 5:55 AM UTC
Poster & Exhibition Venue 1 (Marine Messe Fukuoka Hall A, 1F)
1. Molecular
- a. Genome / Gene / Nucleic Acid
- b. DNA replication
- c. Recombination / Mutation / Repair
- d. Epigenetics / Chromatin
- e. Transcription
- f. RNA / Ribonucleoprotein
- g. Translation
- h. Protein
- i. Carbohydrate / Lipid / Metabolite
- j. Molecular Evolution / Comparative Genomics
- l. Others
2. Cell
- a. Chromosome / Nuclear Body
- b. Phase Separation
- c. Protein Processing / Transport / Localization
- d. Cytoplasmic Membranous Organelle
- e. Cell Adhesion / Cell Motility / Extracellular Matrix
- f. Cell Membrane / Cytoskeleton
- g. Cell Proliferation / Division / Cell Cycle
- h. Signal Transduction (Post Translational Modification)
- i. Signal Transduction (Bioactive Substance)
- j. Cell Death
- k. Others
- a. Genome / Gene / Nucleic Acid
- b. DNA replication
- c. Recombination / Mutation / Repair
- d. Epigenetics / Chromatin
- e. Transcription
- f. RNA / Ribonucleoprotein
- g. Translation
- h. Protein
- i. Carbohydrate / Lipid / Metabolite
- j. Molecular Evolution / Comparative Genomics
- l. Others
2. Cell
- a. Chromosome / Nuclear Body
- b. Phase Separation
- c. Protein Processing / Transport / Localization
- d. Cytoplasmic Membranous Organelle
- e. Cell Adhesion / Cell Motility / Extracellular Matrix
- f. Cell Membrane / Cytoskeleton
- g. Cell Proliferation / Division / Cell Cycle
- h. Signal Transduction (Post Translational Modification)
- i. Signal Transduction (Bioactive Substance)
- j. Cell Death
- k. Others
[3P-001]Recovery and PCR detection of bacteriophage MS2 in the air with sprayed PCR reagents
○Rui Tamura1, Takumi Inoue1, Masahiko Oshige1,2, Shinji Katsura1,2 (1. Dept. of Envi. Eng. Sci., Gunma Univ., 2. GUCFW)
[3P-002]Development of droplet generation method and its application to RT-PCR
○Haruya Wakabayashi1, Shunki Kunitake1, Haruna Miyazawa2, Masahiko Oshige1,2,3, Shinji Katsura1,2,3 (1. Dept. of Envi. Eng. Sci., Gunma Univ., 2. Dept. of Food. Eng., Gunma Univ., 3. GUCFW)
[3P-003]Analysis of mouse genomic imprinted loci that exhibit differences in expression bias between alleles depending on the strains and tissues selected
○Tomoki Nasu1, Ayaka Saito1, Takanori Amano2, Atsushi Yoshiki3, Hidenori Kiyosawa1 (1. Laboratory for Genomic Sciences, Department of Life Science, Chiba Institute of Technology, 2. Next Generation Human Disease Model Team, RIKEN BRC, 3. Experimental Animal Division, RIKEN BRC)
[3P-004]Analysis of gene loci where expression balance between two alleles fluctuates during in vitro neurogenesis by using mouse inter-subspecies F1 hybrid ES cell lines
○Hagumi Suzuki1, Tomoki Nasu1, Ayaka Saito1, Hidenori Kiyosawa1 (1. Lab. for Genomic Sci., Dept. of Life Sci., Chiba Tech.)
[3P-005]DNA origami-based nanodevices for gene-editing
○Ruixuan Wang1, Chenxu Tan1, Hisashi Tadakuma1 (1. ShanghaiTech University)
[3P-006]Epigenetic changes with aging trigger unequal recombination of repetitive sequences by activating transcription of non-coding RNA.
○Yuta Uneme1,2, Yoshio Yamamuro1,2, Hiroshi Kimura3, Takehiko Kobayashi1,2 (1. Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo, 2. Univ of Tokyo, IQB , 3. Tokyo Institute of Technology, IIR)
[3P-007]Induction of MASH and vacuolar structures in the Nwd1-/- mouse liver via SERCA2-dependent endoplasmic reticulum stress
○Miona Funato1, Ogawa Hayato1, Misaki Kato1, Kazuhiko Nakadate2, Takuro Horii3, Izuho Hatada4, Ryosuke Kobayashi3, Seiya Yamada1, Shin-ichi Sakakibara1 (1. Waseda University, 2. Meiji Pharmaceutical University, 3. Gunma University, 4. Gunma University Initiative for Advanced Research)
[3P-008(3PS-15-02)]Analysis of the Dynamics of a Probe Molecule in Nucleic Acid Condensates Formed by Liquid-Liquid Phase Separation
○Makoto Shimizu1,2, Aika Kawakami1,2, Yudai Yamaoki1,2, Keiko Kondo1,2, Tomoki Sakamoto1,2, Takashi Nagata1,2, Masato Katahira1,2 (1. Inst. Adv. Energy, Kyoto Univ., 2. Grad. Sch. Energy Sci., Kyoto Univ.)
[3P-009]Measurement of spider silk properties for data-driven artificial silk design and identification of unknown silk protein sequences using multi-omics analysis
○Yasuha Watanabe1, Hiroyuki Nakamura2, Kazuharu Arakawa1 (1. Institute for Advanced Biosciences, Keio University, 2. Spiber Inc.)
[3P-010]Elucidation of biosynthetic pathway of inosine triphosphate
○Daisuke Tsuchimoto1, Yuka Takiguchi1, Yusaku Nakabeppu1,2 (1. Div. Neurofunctional Genomics, Med. Inst. Bioregulation, Kyushu University, 2. Japan society for the promotion of science, San Francisco Office)
[3P-011]Characterization of genetic variants of equine cathelicidin.
○TAIICHIRO ISHIGE1, Mio Kikuchi1, Kei-ichi Hirota1, Risako Furukawa1, Teruaki Tozaki1, Shun-ichi Nagata1, Hironaga Kakoi1 (1. Laboratory of Racing Chemistry)
[3P-012]A method for detecting gene doping in horse sports without DNA extraction
○Risako Furukawa1, Teruaki Tozaki1, Mio Kikuchi1, Taichiro Ishige1, Yuji Takahashi2, Emiko Fukui3, Hironaga Kakoi1 (1. Laboratory of Racing Chemistry, 2. Equine Research Institute, Japan Racing Association, 3. School of Agriculture, Utsunomiya University)
[3P-013]Long-read sequencing-based method for rapid detection of structural variants
○John Clyde Co Soriano1, Takeru Nakabayashi1, Satoshi Yuhara1 (1. H.U. Group Holdings)
[3P-014]Screening of Staphylococci from Canine Pyoderma for Disinfection Evaluation and Genome Analysis of qacC Positive Staphylococcus coagulans
○Manami Tsunoi1, Manabu Takiguchi2, Emi Ashida2, Keita Iyori2, Koki Shimizu3 (1. The Jikei University School of Medicine, 2. 1sec. Inc., 3. Tokyo University of Science)
[3P-015]Role of transcription termination in retrotransposon silencing by the Piwi-piRNA complex
○Kensaku Murano1, Yaning Wu1, Rin Imai1, Haruhiko Siomi1 (1. Keio Univ. Sch. Med.)
[3P-016]Data-driven human genome annotation using large scale Hi-C data
○Koki Gima1,2, Ryuichiro Nakato1,2 (1. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo., 2. Institute for Quantitative Biosciences, The University of Tokyo)
[3P-017]Genomic analysis of w1 pnd strain in the silkworm
○Takuya Tsubota1, Kakeru Yokoi1 (1. National Agriculture and Food Research Organization)
[3P-018]HUSH complex regulates de-repression of transposable elements during antiviral response
○Shota Azuma1,2, Yuka W Iwasaki2 (1. The University of Tokyo, 2. RIKEN)
[3P-019(3AS-01-07)]Rapid regulation of CRISPR-Cas based applications through inducible degradation of anti-CRISPR proteins
○Toyoaki Natsume1, Ryoko Wada1, Hideya Kawaji1 (1. Research Center for Genome & Medical Sciences, Tokyo Metropolitan Institute of Medical Science)
[3P-020]Development of In silico LAMP (Loop-Mediated Isothermal Amplification) using Generalized Linear Model
○Kenshiro Taguchi1,2, Michiyuki Satoru2, Takumasa Tuji3, Jun'ichi Kotoku1,3 (1. Health Data Science, Teikyo Univ., 2. EIKEN CHEMICAL CO.,LTD., 3. Medical Care and Technology, Teikyo Univ.)
[3P-021]Exploration of Co-receptors for Gustatory Receptors in Swallowtail Butterflies Using Single-nucleus RNA-seq
○Katsuhisa Ozaki1 (1. JT Biohistory Research Hall)
[3P-022]Identification and functional analysis of the mouse Nwd2 gene specifically expressed in the medial habenula.
○Hayato Ogawa1, Misaki Kato1, Seiya Yamada1, Shin-ichi Sakakibara1 (1. Waseda University)
[3P-023]Functional analysis of the human-specific lncRNA gene HSTR1
○Mao Watanabe1, Yuusuke Hamazaki2, Momoka Satou4, Masanori Imamura3, Syunsuke Suzuki1 (1. Grad. Sch. of Sci. and Tec., Agr., Shinshu Univ. , 2. EHUB., Kyoto Univ. , 3. Grad. Sch. of Med. Sci., Kanazawa Univ., 4. Fac. of Agr., Shinshu Univ.)
[3P-024]Effect of Insert Size on Knock-in Rate in Mice with CRISPR/Cas9 and AAV Vectors
○Osamu Suzuki1, Minako Koura1, Kozue Uchio1, Mitsuho Sasaki1, Yuko Doi1, Mayu Kamimura1, Haruhiko Kamada1 (1. National Institutes of Biomedical Innovation, Health and Nutrition)
[3P-025]Development of a gene introduction method for alkaliphilic bacteria
○YOSHIHIRO MURATA1, Junko Yamamoto1, Masakazu Kataoka1 (1. Shinshu University)
[3P-026]Considerations for Efficient Genome editing
○Tomoya Hayashi1,2, Yuichi Mishima1,2, Sou Nakamura3, Naoshi Sugimoto3, Akitsu Hotta3, Hiroyuki Ishii1, Hideki Aso1, Yoshihiro Fujimura1, Yoshihiko Tani2, Takafumi Kimura1,2, Koji Eto3, Yoshihiro Takihara1 (1. Japanese Red Cross Kinki Block Blood Center, 2. Japanese Red Cross Society Blood Service Headquater Central Blood Institute, 3. Center for iPS Cell Research and Application)
[3P-027]Construction of modified silkworm BACs for the production of silkworm artificial chromosomes and their introduction into cultured cells and individuals
○Tomonori Adachi1, Masato Hino2, Hiroaki Mon2, Takahiro Kusakabe2 (1. Kyushu Univ. Bioresource Sci., 2. Kyushu Univ.)
[3P-028]Development of machine learning models utilizing large language models for accelerating nucleic acid drug discovery
○Tomoya Sakuma1,2, Yuki Ohtani1,2, Hirofumi Aso1, Daisuke Koga1, Hideyuki Shimizu1,2 (1. Tokyo Medical Dental Univ.・M&D Data Science Center・Dept. AI Systems Medicine, 2. Tokyo Medical Dental Univ.・Graduate School of Medical and Dental Sciences)
[3P-029]Assessment of clonal variations in mitochondrial DNA of human iPSCs
Ryo Niwa1,2, Miyuki Ono1, Qi Fang1, ○Karen Kai Lin Hwang1,2, Tomoko Matsumoto1, Mandy Siu Yu Lung1, Fabian Oceguera-Yanez1, Anne-Laure Bulteau3, Carine Nizard3, Knut Woltjen1 (1. Department of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan, 2. Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan, 3. LVMH Recherche, Saint Jean de Braye 45804, France)
[3P-030]Protein function prediction by amino acid sequence analysis using natural language processing
○Ryo Arai1, Daiki Koge1, Takashi Abe1 (1. Graduate School of Science and Technology, Niigata University)
[3P-031]Expression and localization analyses of barley P23k gene and protein
○TAODE BILIGE1, MIAN WANG1, Hiroshi Takase1, Shin-ichiro Kidou1 (1. Nagoya City University)
[3P-032(3PS-07-07)]Cold induced small protein (BdCISP2) from Brachypodium distachyon enhances the growth of E. coli and yeast under cold stress conditions
○Arriel Fadhilah1, Shin-ichiro Kido1,2 (1. Graduate School of Science, Nagoya City University, 2. Research Center for Biological Diversity, Nagoya City University)
[3P-033]Intraductal injection-based in vivo gene delivery into mouse mammary glands
○Kazunori Morohoshi1, Masahiro Sato2, Shingo Nakamura1 (1. Division of Biomedical Engineering, National Defense Medecal College Research Institute, 2. Department of Genome Medicine, National Center for Child Health and Development)
[3P-034]Analysis of Expression and Function of a Sclerotin Synthase Gene in Body Color Pattern Formation of the Cricket Gryllus bimaculatus
○Ayane Shimamura1, Shintaro Inoue2, Yoshiyasu Ishimaru3, Katsuyuki Miyawaki2, Akira Takahashi4, Takeshi Nikawa5, Sumihare Noji6, Takahito Watanabe2, Taro Mito2 (1. Div. of Bioresource Science, Graduate School of Sciences and Technology for Innovation, Tokushima Univ., 2. Bio-Innovation Research Center, Tokushima Univ., 3. Div. of Bioscience and Bioindustry, Graduate School of Technology, Industrial and Social Sciences, Tokushima Univ., 4. Dept. of Preventive Environment and Nutrition, Inst. of Biomedical Sciences, Tokushima Univ., 5. Dept. of Nutritional Physiology, Inst. of Biomedical Sciences, Tokushima Univ., 6. Tokushima Univ.)
[3P-035]Elucidating the molecular basis of clonal hematopoiesis using a new AVITI sequencer
○Akinori Kanai1, Yukie Kashima2, Kenichi Makishima3, Mamiko Sakata-Yanagimoto3, Yutaka Suzuki1 (1. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, the University of Tokyo, 2. Life science data research center, Graduate School of Frontier Sciences, the University of Tokyo, 3. Department of Hematology, Faculty of Medicine, University of Tsukuba)
[3P-036]Temperature dependence of gene expression activity in the presence of polyamines
○Shotaro Kato1, Kenichi Yoshikawa1, Yuko Yoshikawa1, Koichiro Sadakane1 (1. Doshisha University)
[3P-037]Targeting Senescence as a Therapeutic Opportunity for bladder cancer
○Ching Wen Liu1, Ming Yuen Wang2, Li Ching Chang 3,4 (1. Department of Natural Biotechnology, Nanhua University, 2. Department of Athletic Performance, National University of Kaohsiung, 3. School of Medicine, I-Shou University, 4. Department of Pharmacy, E-Da Hospital)
[3P-038]Individual identification of aquacultured Pacific bluefin tuna, Thunnus orientalis using genome amplification and dd-RAD-seq method
○YASUO AGAWA1, MASATO KAWAHARA1, RYUUHEI KINAMI1, YOSHIFUMI SAWADA1, KENTA SHIRASAWA2, SACHIKO ISOBE2 (1. Aqua. Res. Inst., Kindai University, 2. KAZUSA DNA Res. Inst.)
[3P-039]Development of highly efficient gene knockout in rice using a modified Type I-D CRISPR-Cas (TiD-X)
○Shota Muromoto1, Hiromichi Ae2, Naoki Wada2, Keishi Osakabe2, Yuriko Osakabe1 (1. Sch. of Life Sci. & Tech., Science Tokyo., 2. Grad. Sch. of Tech., Ind. & Soc. Sci., Tokushima Univ.)
[3P-040]Evaluation of Shin-RamDA-seq by benchmarking single-cell full-length RNA sequencing
○Mika Yoshimura1, Haruka Ozaki3,1, Tetsutaro Hayashi1, Mariko Kuse1, Takumi Ichikawa1, Itoshi Nikaido2,1 (1. RIKEN Center for Biosystems Dynamics Research, 2. Tokyo Medical and Dental University, 3. Tsukuba University)
[3P-041]Genome-wide association study for identification of SNPs in disease resistance genes in Hevea brasiliensis
○Taketeru Otaki1, Fetrina Oktavia2, Tomoko Kuriyama3, Masaharu Kawauchi3, Minami Matsui3, Yuko Makita1,3 (1. Maebashi Tech, 2. IRRI, 3. RIKEN CSRS)
[3P-042]Elucidation of intrinsic features in DNA sequences through long-read sequencing technology
○Hidehito Inagaki1, Katsuyuki Yokoi1, Rie Kawamura1, Yui Shichiri1, Hiroki Kurahashi1 (1. Fujita Health University)
[3P-043]Multi-omics Profiling of Chimeric Genomes Harboring Becillus subtilis str. 168 and natto
○Mia Matsumoto1,2, Ruka Takegawa2,3, Nobuaki Kono1,2,4 (1. Faculty of Environment and Information Studies, Keio University, 2. Institute of Advanced Biosciences, Keio University, 3. Faculty of Policy Management, Keio University, 4. Graduate School of Media and Governance, Keio University)
[3P-044]Higher-order structure of the DNA-histone H1 complex and gene expression
○Kosuke Imanaka1, Takashi Nishio2, Yuko Yoshikawa1, Takahiro Kenmotsu1, Kenichi Yoshikawa1 (1. Facul. Life. Med. Sci., Doshisha Univ., 2. National Institute of Advanced Industrial Science and Technology (AIST))
[3P-045]Genome analysis of Ralstonia sp. NT80, an eubacterium with Lipase super-induction ability
○Morio Ishizuka1, Shu Katsuragi1, Genki Akanuma2, Kazutoshi Ushio3 (1. Chuo Univ., 2. Josai Univ., 3. Niihama Natl. College)
[3P-046]Haplotype-resolved genome assembly of Spinach and gene comparison between haploids
○Sakiko Terano1, Sangwan Kim1, Shusuke Maeda2, Atsushi Toyoda3, Sachiko Isobe4,5, Kenta Shirasawa5, Yasuyuki Onodera2, Hideki Hirakawa1 (1. Kyushu Univ., 2. Hokkaido Univ., 3. Nat. Inst. Genet., 4. Tokyo Univ., 5. Kazusa DNA Res. Inst.)
[3P-047]Screening of telomere DNA structure-selective ligands and evaluation of their intracellular effects
○Masaya Gessho1, Yoshiki Hashimoto1, Kohei Takeuchi1, Wataru Sugimoto1, Lee Sunmin1, Akito Nomoto1, Hideaki Hujita2, Keiko Kawauchi1, Daisuke Miyoshi1 (1. Faculty of frontiers of Innovative Research in Science and Technology (FIRST), Konan University , 2. Department of Stem Cell Biology, Research Institute for Radiation Biology and Medicine, Hiroshima University)
[3P-048]Alteration of the inverted repeat sequences in the chloroplast genome
○Hikaru Sugita1, Yoshinori Fukasawa1 (1. Utsunomiya University)
[3P-049]The mechanisms of gRNA-dependent variation in CRISPR-Cas9 cleavage efficiency
○Kanae Aoki1, Yusuke Kamachi1 (1. Sch. of Eng. Sci., Kochi Univ. of Tech.)
[3P-050]The Challenges to Reproducibility - Expanding Real-Time PCR Proficiency Testing
○Hiroki NAKAE1,2,3, Nobuhiro Gemma1, Junko Ikeda1,2,3, Keiko Misawa1,2,3, Mari Onishi4, Satoshi Futo1,4 (1. Japan Biotechnology Cirtification Organization, 2. Japan bio Measurement & Analysis Consortium, 3. Council for Industrial use of Biological and Environmental Repositories , 4. Fasmac Co., Ltd.)
[3P-051]Molecular design of inactive structure of RNA sensors for ASO detection
○Emiri Matsusaka1, Yuuka Watahiki1, Okada Yoshihiro1, Nae Sakimoto2, Junji Kawakami1,2 (1. FIRST, Konan University, 2. KOLOT)
[3P-052]Development of a highly efficient method for RNA extraction from fixed tissue sections and gene expression analysis of ovarian follicles
○Hiroki Ikeda1, Shintaro Miyao1, Nanami Yamada1, Tomoya Takashima1, So Nagaoka1, Sze-Ming Law1, Kazuki Kurimoto1 (1. Nara medical university)
[3P-053]Generation of Genetically Modified Mice and Cell Line for Functional Analysis of the Olfactory Receptor Specifically Expressed in Germ Cells and Cancer Cells
○Norio Takei1, Akinobu Ota2,3, Takayuki Sakurai4 (1. Inst. Animal exp., Faculty Med., Hokkaido Univ., 2. Dept. Nutr. Food. Environ., Kinjo Gakuin Univ., 3. Dept. Biochem., Sch. Med., Aichi Med. Univ, 4. Dept. Cardio. Res., Sch. Med., Shinshu. Univ.)
[3P-054]Development of a mapping-free and fast genome-guided RNA-seq assembler for Eukaryotes
○Makoto Terauchi1, Hideki Noguchi1 (1. Center for genome informatics, DS, ROIS)
[3P-055]Comprehensive Exploration and Visualization of Age-Related Genes Using a Data-Driven Machine Learning Approach
○Hiroki Endo1,2, Tetsuo Ishikawa3,4,5, Motoshi Hayano2 (1. St. Marianna University School of Medicine, 2. Department of Orthopaedic Surgery, Keio University, 3. Department of Extended Intelligence for Medicine, The Ishii-Ishibashi Laboratory, Keio University School of Medicine, Tokyo, Japan, 4. Advanced Data Science Project, RIKEN Information R&D and Strategy Headquarters, RIKEN, Yokohama, Japan, 5. Collective Intelligence Research Laboratory, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan)
[3P-056]Proper accumulation and dissociation of CRL4Cdt2 at DNA synthesis sites regulate cell cycle progression
○Tatsuya Bekki1, Masayuki Kusakabe2,3, Akiko Ueno1, Yasushi Shiomi1, Kaoru Sugasawa2,3, Akiyo Hayashi1, Hideo Nishitani1 (1. Grad. Sch. of Sci., Univ. of Hyogo, 2. Biosignal Res. Ctr., Kobe Univ., 3. Grad. Sch. of Sci., Kobe Univ.)
[3P-057]Deployment strategy of BITREx, a method for expansion of tandem gene arrays: development of sgRNA searching method and its practice in HEK293T cells
○Hiroaki Takesue1, Satoshi Okada1, Emiko Kusumoto1, Takashi Ito1 (1. Dept. Biochem., Grad. Sch. Med. Sci., Kyushu Univ.)
[3P-058]ATR coordinates the interplay between replication stress tolerance factors in response to oncogenic KRAS activation
○Taichi Igarashi1,2,3, Takaaki Yasuhara1, Bunsyo Shiotani2 (1. Laboratory of Genome Stress Response, Graduate School of Biostudies, Radiation Biology Center, Kyoto University, 2. Laboratory of Genome Stress Signaling, National Cancer Center Research Institute, 3. Department of Bioscience, School of Science, Kitasato University)
[3P-059(3AS-12-05)]Cell growth-coordinated regulation of the function of the DNA bending factor IHF for ensuring timely replication initiation
○Kazutoshi Kasho1, Mizuki Yoshida1, Rion Satomura1, Kenya Miyoshi1, Wataru Nakagaki1, Sho Nakazono1, Tsutomu Katayama1 (1. Kyushu Univ., Grad. Sch. Pharm. Sci.)
[3P-060]Understanding the mechanism for control of early replication timing by DNA cis elements.
○Satoshi Uchino1, Takayo Sasaki1, David M Gilbert1 (1. San Diego Biomedical Research Institute)
[3P-061]The alteration of DNA polymerase usage in CyclinE1 overexpressing cells
○Takahiro Yamaguchi1,2, Lewis Bainbridge1, Tamiko Minamisawa1, Mami Takahashi1, Shu Kondo2, Yasukazu Daigaku1 (1. Japanese foundation for cancer research, 2. Tokyo university of science)
[3P-062]Control of PCNA removal from chromatin and its contribution to genome maintenance
○Yasushi Shiomi1, Akiyo Hayashi1, Masato T Kanemaki2,4, Chikashi Obuse3, Hideo Nishitani1 (1. Grad. Sch. of Sci., Univ. of Hyogo, 2. NIH, 3. Grad. Sch. of Sci., Osaka Univ., 4. Grad. Sch. of Sci., Univ. of Tokyo)
[3P-063]The analysis of replication initiation mechanism coordinated with spatial arrangement of the replication origin in Caulobacter crescentus.
○Ayaka Kubaru1, Shogo Ozaki1, Tsutomu Katayama1 (1. Kyushu Univ.)
[3P-064(3PS-10-04)]Smarcad1 and MutSα catalyze unidirectional sliding of a nucleosome away from a mismatch to facilitate mismatch repair on chromatin
○Eiichiro Kanatsu1, Riki Terui2, Tamiko Minamisawa3, Yasukazu Daigaku3, Tatsuro Takahashi2 (1. Graduate School of Systems Life Sciences, Kyushu University, 2. Faculty of Science, Kyushu University, 3. Cancer Institute, Japanese Foundation for Cancer Research)
[3P-065]Catalytically inactive Cas9 attenuates DNA end resection: a potential application for region-restricted random mutagenesis
○Suchin Towa1, Satoshi Okada1, Takashi Ito1 (1. Kyushu University Graduate School of Medical Sciences)
[3P-066]Genome Editing Efficiency in Medaka at Different Temperatures
○Takashi Yamanaka1, Akiko Sogo1, Masato Kinoshita1 (1. Kyoto Univ.)
[3P-067]Quantitative analysis of the mismatch repair complex, MutL, using the fluorescent reporter plasmid
○Ryosuke Fujikane1,2, Mai Takagi1, Isao Kuraoka3, Masumi Hidaka1,2 (1. Fukuoka Dental College, Dept. of Physiol. Sci. and Mol. Biol., 2. Fukuoka Dental College, Oral Med. Res. Center, 3. Fukuoka Univ. Fac. of Sci.)
[3P-068]Mechanism of abnormal DNA structure in aged budding yeast
○Kohshiroh Sakamoto1,2, Takehiko Kobayashi2 (1. Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo, 2. IQB., Univ. of Tokyo)
[3P-069]Characterizing DNA double-strand break repair in myosin IIA knockout cell line
○Ryotaro Nishi1,2, Yukiyoshi Nomura1, Iris Sako2 (1. Molecular Biology Laboratory, Graduate School of Bionics, Tokyo University of Technology, 2. Molecular Biology Laboratory, Department of Bioscience and Biotechnology., Tokyo University of Technology)
[3P-070]Regulatory mechanisms of DSB repair in coordination with chromatin remodeling and transcription of damage-induced RNA in Arabidopsis
○Kohei Kawaguchi1, Mei Kazama1, Takayuki Hata2, Mitsuhiro Matsuo3, Junichi Obokata3, Soichirou Satoh1 (1. Kyoto Prefectural University, 2. Hirosaki University, 3. Setsunan University)
[3P-071]Split MutT prevents the mutator phenotype of mutT-deficient Escherichia coli
○Hiroyuki Kamiya1 (1. Grad. Sch. Biomed. Hlth. Sci., Hiroshima Univ.)
[3P-072]Identifying and characterizing novel RG/RGG motif-containing proteins involved in DSB repair and responses
○Miko Urano1, Ryotaro Nishi1 (1. Mol. Biol. Lab.,Grad. Sch. Bionics, Tokyo Univ. Tech.)
[3P-073]Functional analysis of RAD52 in the replication stress response induced by lacO-LacI complex on human chromosomes
○Kosei Matsushita1, Koki Narimatsu1, Kazumasa Yoshida1, Yasunori Noguchi1, Miyako Shiraishi1, Yoko Katsuki1, Masatoshi Fujita1 (1. Kyushu Univ.)
[3P-074]Effects of redox molecular chaperon hslO point mutations on lethality with chromosomal damage in Escherichia coli.
○Akihiro Kaidow1, Ran Yuxin1, Hirokazu Kasahara1 (1. Tokai Univ.)
[3P-075(3PS-10-05)]Biochemical and structural analyses of the DNA damage recognition by XPF-ERCC1 in the nucleosome
○Aya Yoshida1,2, Syota Matsumoto1, Yoshimasa Takizawa1, Mitsuo Ogasawara1, Isao Kuraoka3, Hitoshi Kurumizaka1,2 (1. IQB, The Univ. of Tokyo, 2. Dept. of Biol. Sci., Grad. Sch. of Sci., The Univ. of Tokyo, 3. Dept. of Chem., Grad. Sch. of Sci., Fukuoka Univ.)
[3P-076]ATM/ATR-dependent phosphorylation is required for DNA double-strand break resection promoted by splicing factor SART1
Kie Ozaki1, Yuki Uchihara2, Yu Abe3, Takaaki Yasuhara4, Atsushi Shibata2, ○Motohiro Yamauchi1 (1. Kyushu University, 2. Keio University, 3. Nagasaki University, 4. Kyoto University)
[3P-077]Development of FirmCut TALE nickase for highly efficient and highly accurate gene knock-in
○Marina Akase1,2, Tadahiko Yoshima3, Tetsushi Sakuma2 (1. Graduate School of Integrated Sciences for Life, Hiroshima University, 2. Graduate School of Agriculture, Kyoto University, 3. Bioscience Research Laboratory, Sumitomo Chemical Co., Ltd)
[3P-078]Elucidation of the spatial regulation of DNA double-strand break repair in the human nucleus
○Hayaki Ikegame1, Ryotaro Nishi1 (1. Mol. Biol. Lab., Grad. Sch. Bionics, Tokyo Uni. Tech.)
[3P-079]Roles of histone modification in regulation of DNA damage recognition initiating nucleotide excision repair
○Mizuki Watada1,2, Masayuki Kusakabe1,2, Takumi Maeda1,2, Erina Kakumu1,2, Masayuki Yokoi1,2, Wataru Sakai1,2, Kaoru Sugasawa1,2 (1. Biosignal Res. Ctr., Kobe Univ., 2. Grad. Sch. Sci., Kobe Univ.)
[3P-080]Development of the method for nucleic acid-protein complex into prokaryotic cells toward genome editing.
○Satsuki Ueda1, Hirokazu Takahashi1, Yoshiko Okamura1 (1. Graduate School of Hiroshima)
[3P-081]Engineering of a new genome editing tool, TiD-X, toward highly efficient and specific genome editing
○Naoki Wada1, Emi Murakami1, Kazuya Marui1, Yuriko Osakabe2, Keishi Osakabe1 (1. Tokushima University, 2. Science Tokyo)
[3P-082]Development of genetic tools for Halomonas sp. A020
○Mei Hirata1, Yoshinao Azuma1 (1. Kindai Univ.)
[3P-083(3PS-10-08)]Human AAA+ ATPase FIGNL1 facilitates post-replicative disassembly of RAD51 to suppress RAD51-mediated ultra-fine bridge formation
○Kenichiro Matsuzaki1, Miki Shinohara1,2 (1. Grad. Sch. Agri., Kindai Univ., 2. ATIRI, Kindai Univ.)
[3P-084]Analyzing RAD52 DNA repair functions using FRET-based biochemical methods
○Chiaki Kinoshita1, Yoshimasa Takizawa2, Hitoshi Kurumizaka2, Wataru Kagawa1 (1. Dept. of Chem., Grad. Sch. Sci. Eng., Meisei Univ., 2. Inst. Quant. Biosci., Univ. of Tokyo)
[3P-085]Structural and biochemical insights into PCNA-mediated DNA cleavage enhancement of mismatch-specific endonuclease EndoMS
○Tomoko Idogawa1, Yoshika Mizushima1, Sonoko Ishino1, Yoshizumi Ishino1, Tomoyuki Numata1 (1. Kyushu Univ.)
[3P-086]Dose-rate effects in the effects of radiation on autophagy
○Takahito Moriwaki1 (1. Institute for Environmental Sciences)
[3P-087]Erythropoietin expression by the Tet one expression guidance system in the treatment of feline renal anaemia
○Fumika Kondo1, Hisashi Hisatomi1 (1. Seikei university)
[3P-088]Analysis of the mechanism about the maintenance of human
○Masaki Kobayashi1, Hori Yutaro2, Takehiko Kobayashi2 (1. The univ. of Tokyo, 2. IQB)
[3P-089]Attempts to develop a new concept of genotoxicity test using BioID technology
○Tsukasa Matsunaga1, Yuta Takahashi1, Shunki Inoue1, Joichiro Sugiura1, Ryo Akahori1, Mitsuo Wakasugi1 (1. Kanazawa University)
[3P-090]Novel reporter plasmids for fluorescence-based evaluation of mismatch repair in living cells
○Haruto Kojima1, Yoshihiro Fujimura1, Rui Oda2, Hayato Nishino2, Gakuto Fukushima1, Ayano Baba2, Kosuke Matsuo1, Isao Kuraoka1, Arato Takedachi1 (1. Department of Chemistry, Graduate school of Science, Fukuoka University, Japan, 2. Department of Chemistry, Faculty of Science, Fukuoka University, Japan)
[3P-091]Novel reporter plasmids for fluorescence-based evaluation of DNA damage response in living cells
○Yoshihiro Fujimura1, Gakuto Fukushima1, Kousuke Matsuo1, Haruto Kojima1, Ayano Baba2, Hayato Nishino2, Rui Oda2, Isao Kuraoka1, Arato Takedachi1 (1. Functional biochemistry group, Department of Chemistry, Graduate school of Science, Fukuoka University, 2. Functional biochemistry group, Department of Chemistry, Faculty of Science, Fukuoka University)
[3P-092]A novel assay for visualizing non-homologous end joining repair proficiency in live cells
○gakuto fukushima fukushima1, Kosuke Matsuo1, Yoshihiro Fujimura1, Haruto Kojima1, Ayano Baba2, Hayato Nishino2, Rui Oda2, Isao Kuraoka1, Arato Takedachi1 (1. Functional biochemistry group, Department of Chemistry, Graduate school of Science, Fukuoka University, Japan, 2. Functional biochemistry group, Department of Chemistry, Faculty of Science, Fukuoka University, Japan)
[3P-093]Quest for the gene responsible for orange coloration of calico cats (1)
○Hidehiro Toh1, Wan Kin Au Yeung2, Motoko Unoki3, Yuki Matsumoto4, Yuka Miki5, Yumiko Matsumura6, Yasukazu Nakamura7, Miho Matsuda8, Hiroyuki Sasaki9 (1. AGC, NIG, 2. Liberal Arts, ICU, 3. Sch. Med., Univ. Tokyo, 4. Azabu Univ./Anicom Inc., 5. Sch. Med., Nagoya Univ., 6. Inakazu Animal Hosp., 7. Genome Info., NIG, 8. Dental Sci., Kyushu Univ., 9. MIB, Kyushu Univ.)
[3P-094]Quest for the gene responsible for orange coloration of calico cats (2)
○Miho Matsuda1, Wan Kin Au Yeung2, Motoko Unoki3, Yuki Matsumoto4, Yuka Miki5, Yumiko Matsumura6, Yasukazu Nakamura7, Hidehiro Toh8, Hiroyuki Sasaki9 (1. Dental Sci., Kyushu Univ., 2. Liberal Arts, ICU, 3. Sch. Med., Univ. Tokyo, 4. Azabu Univ./Anicom Inc., 5. Sch. Med., Nagoya Univ., 6. Inakazu Animal Hosp., 7. Genome Info., NIG, 8. AGC, NIG, 9. MIB, Kyushu Univ.)
[3P-095]Shaping Epigenome Landscape at Gene Promoters through Resetting Histone Modification in the Mouse Germ Cells
○Peilin Li1, Haruka Narita1, Yuta Uneme1,2, Masahide Seki3, Mengwen Hu4, Satoshi H. Namekawa4, Azusa Inoue5,6, Shehroz S. Khan7, James R. Davie8, Yutaka Suzuki3, Ahmed Ashraf9, Mikiko C. Siomi1,2, Soichiro Yamanaka1 (1. Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2. Department of Biophysics and Biochemistry, Faculty of Science, The University of Tokyo, 3. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, 4. Department of Microbiology and Molecular Genetics, University of California, Davis, 5. Laboratory for Epigenome Inheritance, RIKEN Center for Integrative Medical Sciences, 6. Tokyo Metropolitan University, 7. KITE, University Health Network, 8. Department of Biochemistry and Medical Genetics, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, 9. Department of Electrical and Computer Engineering, University of Manitoba)
[3P-096]Essentiality of DNMTs for human cell survive
○Atsuki Matsumoto1, Momoka Ishimine2, Taichi Akase1,3, Yasunori Aizawa1,4,5 (1. Science Tokyo, 2. Tokyo Instituute of Technology, 3. IMS, Riken, 4. KISTEC, 5. Logomix Inc.)
[3P-097]Relationship between the formation of transcriptionally-active chromatin domain and the change in the physical properties of the nucleoplasm
○Saya Ichihara1, Yuko Sato2,3, Hiroshi Kimura2, Akatsuki Kimura1,4 (1. National Insitute of Genetics, 2. School of Life Science and Technology, Tokyo Institute of Technology, 3. Present address: Kyusyu Univ, 4. SOKENDAI)
[3P-098]A role of Polycomb replessive complex 1 (PRC1) in the vicinity of the fork to safeguard the epigenetic maturation of chromatin
○Junichiro Takano1, Shinsuke Ito1, Haruhiko Koseki1 (1. RIKEN)
[3P-099(3AS-12-04)]The functional role of histone H3K4me1 in chromatin contacts and gene activation during embryonic stem cell differentiation
○Naoki Kubo1,2, Hiroyuki Sasaki3, Bing Ren4 (1. RIKEN BRC, 2. Research Institute for Microbial Diseases, Osaka University, 3. Kyushu University, 4. UC San Diego)
[3P-100]Design of live imaging probe specific to histone modifications using ProteinMPNN
○Daiki Maejima1, Yuko Sato2, Timothy J. Stasevich2,3,4, Hiroshi Kimura1,2,4 (1. Department of Life Science and Technology, Science Tokyo, 2. Institute of Innovation Research(IIR), Tokyo Institute of Technology, 3. Colorado State University, 4. Institute of Integrated Research (IIR), Science Tokyo)
[3P-101]Isolation of specific cell types using intracellular staining for transcriptome and epigenome analysis
○Kai Suzuki1, Hiroki Sugishita1,2, Yukiko Gotoh1,2 (1. Faculty of Pharmaceutical Science, University of Tokyo, 2. IRCN, University of Tokyo)
[3P-102]Analysis of histone modifications and the interaction between HBV genome and host cellular genome in vitro HBV infection system
○Daichi Komiyama1, Atsushi Okabe1,2, Hirotake Kasai3, Masaki Fukuyo1, Bahityar Rahmutulla1, Koichi Watashi4, Kohji Moriishi3, Atsushi Kaneda1,2 (1. Dept. Mol. Oncol., Grad. Sch. Med., Chiba Univ., 2. Health and Disease Omics Center, Chiba Univ., 3. Dept. Microbiol., Grad. Sch. Med., Univ. Yamanashi., 4. Dept. Virol. II, NIID.)
[3P-104]Establishment of the bi-directional reporter system evaluating chemical-induced epigenetic effects
○Haruto Yamada1, Keigo Yamakita1, Mizuki Odagiri1, Manabu Yasui2, Masamitsu Honma2, Kei-ichi Sugiyama2, Kiyoe Ura1, Akira Sassa1 (1. Graduate School of Science and engineering, Chiba University, 2. Division of Genome Safety Science, National Institute of Health Sciences)
[3P-105(3AS-15-01)]The effect results from interaction between RNA binding protein FUS and m6A modified RNAs.
○Ryoma YONEDA1, Naomi UEDA1, Riki KUROKAWA1 (1. Div. Biomed. Sci., Saitama Med. Univ.)
[3P-106]Aberrant expression of SETD1A promotes tamoxifen resistance in estrogen receptor α-positive breast cancer cells
○Mingli Jin1, Jaerim Lee1, Yeonjeong Kim1, Minjoo Jo1, Kwang won Jeong1 (1. Gachon university)
[3P-107]Elucidating iron-dependent regulation of epigenetics during adipocyte differentiation
○Tomohiro Suzuki1, Tetsuro Komatsu1, Hiroshi Shibata1, Akiko Tanioka1, Reika Kawabata1, Fumihito Miura2, Shinnosuke Masuda1, Mayuko Hayashi1, Kyoko Tanimura1, Takashi Ito2, Takeshi Inagaki1 (1. Gunma University, 2. Kyushu University)
[3P-108(3AS-15-04)]Development and application of a method for targeted long read DNA methylation analysis
○Masahide Seki1, Keisuke Kunigo1, Satoi Nagasawa1, Ayako Suzuki1, Yutaka Suzuki1 (1. Dept. of CBMS, GSFS, The University of Tokyo)
[3P-109]Histone methyltransferase NSD2 controls B cell proliferation and Igh rearrangement.
○Eito Yagi1, Taichi Isono1, Koh Iwasaki1, Tomoko Kawai2, Kenichiro Hata3, Akira Sassa1, Kiyoe Ura1 (1. Dept. of Biol., Grad. Sch. of Sci., Chiba Univ., 2. Dept. of MFB., Res., NCCHD, 3. Dept. of MolCellBiol., Grad. Sch. of Med., Gunma Univ.)
[3P-110]Analysis of the behavior of cleaved histone H3 during mouse meiosis
○Yasuhiro Fujiwara1, Kenzo Miura1, Yuko Fukuda1, Chizuko Koga1, Erina Inoue1, Yuki Okada1 (1. Univ. Tokyo)
[3P-111]The regulation of cell migration and differentiationby acetylated histone binding proteinBET-1
○Ryota Nakao1, Kiyoji Nishiwaki1, Yukimasa Shibata1 (1. Kwansei Gakuin University)
[3P-112]Alu_474 bp DNA reconstitutes a unique nucleosome positioning in vitro
○Masato Saito1, Kaori Okizumi1, Yurie Kidokoro1, Masaki Kajikawa2, Noriyuki Suka1 (1. Dep. of Chem., Grad. Sch. of Sci. Eng., Meisei Univ. Tokyo, Japan, 2. Graduate school of bioscience and biotechnology, Tokyo Institute of Technology)
[3P-113]Effects of chromatin structure on the enzymatic activity of the histone methyltransferase NSD2.
○Hiroto Isobe1, Nozomi Koike1, Akira Sassa1, Masaki Kikuchi2, Takashi Umehara3, Naoki Horikoshi4, Hitoshi Kurumizaka4, Kiyoe Ura1 (1. Dept. of Biol., Grad. Sch. of Sci., Chiba Univ, 2. Med. Res. Inst., Tokyo Medical and Dental Univ, 3. BDR, RIKEN, 4. IQB, Tokyo Univ)
[3P-114]Cryo-EM structure of active/inactive forms of USP7 bound to DNMT1
○Nao Nakamura1, Sae Yoshimi1, Amika Kikuchi1, Hiroki Onoda2, Satomi Kori1, Makoto Nakanishi3, Atsuya Nishiyama3, Kyohei Arita1 (1. Graduate School of Medical Life Science, Yokohama City University, 2. Synchrotron Radiation Research Center, Nagoya University, 3. Division of Cancer Cell Biology, The Institute of Medical Science, The University of Tokyo)
[3P-115]Single-cell profiling of m6A methylome landscapes in complex tissues
○Kiyofumi HAMASHIMA1, Ka Wai WONG1, Jia Hao Jackie TEO1,2, Reshma TANEJA2, Hu LI3, Yuin-Han LOH1,2 (1. IMCB, A*STAR, Singapore, 2. NUS, Yong Loo Lin School of Medicine, Singapore, 3. Center for Individualized Medicine, Mayo Clinic)
[3P-116(3MS-14-03)]Unveiling the molecular basis of irreversible epigenetic heterogeneity
○Takuya Kajitani1, Hiroaki Kato2, Hiroshi Kimura3, Yasuyuki Ohkawa4, Chikashi Obuse5, Damien Hermand6, John Lis7, Yota Murakami8 (1. Univ. of Fukui, 2. Shimane Univ., 3. Tokyo Tech, 4. Kyushu Univ., 5. Osaka Univ., 6. Univ of Namur, 7. Cornell Univ., 8. Hokkaido Univ.)
[3P-117]Identification of genomic hubs and analysis of epigenome in mouse models of ATR-X syndrome
○Karin Hori1, Masanari Otsuka1, Namiki Doi1,2, Norifumi Shioda1,2 (1. Dept. Geno. Neurol., Univ. of Kumamoto, 2. Grad. Sch., Univ. of Kumamoto)
[3P-118]The Role and Significance of the Epigenome in Age-Associated Neurodegenerative Diseases
○Kaoru Nagamatsu1,2, Mai Saeki1, Yusuke Kishi1 (1. The University of Tokyo / Institute for Quantitative Biosciences, 2. The University of Tokyo / Graduate School of Agricultual and Life Sciences)
[3P-119]Implementation and Benchmarking of an Automated Hi-C Protocol
○Toutai Mitsuyama1, Kikumi Hata1 (1. National Institute of Advanced Industrial Science and Technology (AIST))
[3P-120]Clarification of the Mechanism of Carcinogenesis by the MED Complex and Drug Screening Targeting This Complex
○Sailakshmi Iyer1, Naoko Hattori1, Takeya Nakagawa1, Takashi Ito1 (1. Graduate School of Biomedical Sciences, Nagasaki University)
[3P-121]GATA3 DNA binding affinity and its influence on chromatin structure regulation
○Mika Saotome1,2, Aerica Nagornyuk2, Motoki Takaku2 (1. Tokyo Institute of Technology, 2. University of North Dakota)
[3P-122]Application of thermostable DNA methyltransferase M.ApeKI to PCR
○Mao Hayashi1,2, Yasuhiro Iida1,3, Ryo Futashima4, Toru Uda4 (1. Grad. Sch. Eng., Kanagawa Inst. Technol., 2. JSPS, DC2, 3. Dept. Eng., Kanagawa Inst. Technol., 4. NOK Corp.)
[3P-123]Analysis of cooperative gene expression by nuclear CK2 and transcription factors
○Michiru Risa Fukuda1, So Yamamoto2, Miwako Homma1 (1. Fukushima Medical University, 2. Shirakawa Kosei General Hospital)
[3P-124]Effect of Trim28 knockout on gene regulation in cardiac myocytes
○Kyohei Oyama1, Hiroki Tanaka2, Yoshitaka Tateishi1, Hiroyuki Kamiya1 (1. Asahikawa Medical University, Cardiac Surgery, 2. Asahikawa Medical University, Department of Pathology, Division of Tumor Pathology)
[3P-125]Reconstituted long chromatin array reveals modification pattern-dependent structure
○Yohsuke T. Fukai1, Tomoya Kujirai2, Masatoshi Wakamori3, Hitoshi Kurumizaka2, Takashi Umehara3, Kyogo Kawaguchi1,4,5 (1. Nonequilibrium Physics of Living Matter RIKEN Hakubi Research Team, RIKEN Center for Biosystems Dynamics Research, 2. Institute for Quantitative Biosciences, The University of Tokyo, 3. Laboratory for Epigenetics Drug Discovery, RIKEN Center for Biosystems Dynamics Research, 4. RIKEN Cluster for Pioneering Research, 5. Institute for Physics of Intelligence, The University of Tokyo)
[3P-126]TAS1440, an LSD1 Inhibitor, Exhibits Antitumor Activity by Targeting TGF-β and JAK STAT Signaling in Acute Myeloid Leukemia
○YINGBO GONG1, Sayaka Tsukioka2, Takumitsu Machida2, Akitoshi Nakayama1, Naoko Hashimoto1, Shuichi Ohkubo2, Tomoaki Tanaka1 (1. Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University, 2. Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd)
[3P-127]DNA methylation dynamics of the ribosomal RNA gene (rDNA) in mammalian gametogenesis and early development
○Yutaro Hori1, Takehiko Kobayashi1 (1. IQB, Univ. of Tokyo)
[3P-128]BRAF V600E induces cardiomyocyte dedifferentiation via changing the epigenetics of sarcomere-related genes.
○Kyoko Ueda1, Hisakazu Kato2, Seiji Takashima1,2 (1. Dept. of Med. Bio., Grad. Sch. of Fro. Bio., Univ. of Osaka, 2. Dept. of Med. Bio., Grad. Sch. of Med. , Univ. of Osaka)
[3P-129]Elucidation of genomic imprinting maintenance mechanisms through the development of high-resolution spatial omics technology
○Hiroaki Ohishi1, Hiroshi Ochiai1 (1. Kyushu Univ. MIB)
[3P-130]Characterizing single-molecule open chromatin patterns around CTCF binding sites with Fiber-seq
Akira Hirota1, Takuya Yamamoto1,2, ○Taro Tsujimura1 (1. ASHBi, Kyoto Univ., 2. CiRA, Kyoto Univ.)
[3P-131]IER5-PP2A-mediated MDM2 dephosphorylation and p53 stability
○Taisei Nakada1, Mayuko Koga1, Haruka Sugiyama1, Hirosi Sakurai1 (1. Kanazawa Univ.)
[3P-132]PP2A adapter proteins differentially regulate the phosphorylation state and activity of heat shock transcription factor HSF1
○Haruka Sugiyama1, Taisei Nakada1, Honoka Kakuda1, Rena Hanke1, Koyo Yano1, Hiroshi Sakurai1 (1. Kanazawa University)
[3P-133]Deciphering the coordination of regulatory factors and transcription burst in real time at a single gene locus
○Bitong Li1,2, Yew Yan Wang2,4, Neftali Rodriguez4, Tara Davidson2, Matthew Graus2,4, Valeriia Smialkovska 5, Angelika Feldmann 5, Hiroshi Ochiai 3, Mathias Francois2,4 (1. University of New South Wales, 2. Centenary Institute, 3. Kyushu University, 4. University of Sydney, 5. German Cancer Research Center (DKFZ))
[3P-134]Comparative TSS-seq of Arabidopsis accessions revealed genetic stability of genic and non-genic promoters and middle-scale tuning of transcription during local adaptation
○Kazuki Sugekawa1, Okechukwu Samson Ezeh2, Yoshiharu Y Yamamoto1,2,3,4 (1. Gifu Univ. Grad Sch of Nat Sci Tech., 2. Gifu Univ. UGSAS., 3. Gifu Univ. Fuc Appl Biol., 4. Riken CSRS.)
[3P-135]IRF2BP2 is a Novel Transcriptional Repressor that Inhibits HNF4α Transcriptional Activity and Suppresses Gluconeogenesis in the Liver
○Takumi Kouketsu1, Atsushi Yokoyama1, Hiroki Shima2, Kazuhiko Igarashi2, Akira Sugawara1 (1. Department of Molecular Endocrinology, Tohoku University Graduate School of Medicine, 2. Department of Biochemistry, Tohoku University Graduate School of Medicine)
[3P-136]Investigation of HSF1-interacting proteins using TurboID
○Ryosuke Takii1, Masaki Matsumoto2, Kritika Jaiswal1, Akanksha Pandey1, Mitsuaki Fujimoto1, Akira Nakai1 (1. Dept. of Biochem. & Mol. Biol., Grad. Sch. of Med., Yamaguchi Univ., 2. Dept. of Omics & Systems Biol., Grad. Sch. of Med. & Dent. Sci., Niigata Univ.)
[3P-137]SUMOylated Senataxin suppresses transposable elements in the Drosophila Piwi-piRNA pathway
○Rin Imai1, Yaning Wu1, Haruhiko Siomi1, Kensaku Murano1 (1. Keio University)
[3P-138]Regulation of Rho-dependent termination by Rof protein with its upstream ORF in Bacteria
○Mizuki Igarashi1,2, Rerina Inose2, Teppei Morita1,2 (1. Grad. Sch. Media Gov., Keio Univ., 2. Inst. Adv. Biosci., Keio Univ.)
[3P-139]Mediator subunit MED17 is a novel coactivator for GATA1 N-terminal activation domain
○ASUKA TANAKA1, Fuki Kumagai1, Hikaru Tsutsumi1, Kazuki Tsutsui1, Miyu Kozaki1, Ayu Muranaka1, Miyu yoshimura1, chisaki nakamura1, Kyoka Imoto1, Hanayo Watanabe1, Natsuki Aoto1, Robert G. Roeder2, Natsumi Hasegawa1, mitsuhiro ito1,2 (1. Medical Biophysics, Kobe Univ., 2. Biochem. & Mol. Biol., the Rockefeller Univ.)
[3P-140]Inference of temporal development for RNA kinetics using nucleotide labeling
○Kentaro Kawata1, Masahide Seki2, Akinori Kanai2, Yutaka Suzuki2 (1. AIST, 2. Univ of Tokyo)
[3P-141]GATA1 N-terminal activation domain interacts specifically with Mediator subunit MED14
○Hanayo Watanabe1, Fuki Kumagai1, Miyu Kozaki1, Moeki Onishi1, Hikaru Tsutsumi1, Asuka Tanaka1, Kazuki Tsutsui1, Miyu Yoshimura1, Chisaki Nakamura1, Ayu Muranaka1, Manaka Fujieda1, Robert G Roeder2, Natsumi Hasegawa1, Mitsuhiro Ito1 (1. Medical Biophysics,Kobe Univ., 2. Biochem.&Mol.Biol.,the Rockefeller Univ.)
[3P-142]Identification of modification enzymes responsible for two pseudouridines of the anti-Shine-Dalgarno sequence region in Thermus thermophilus 16S rRNA
○Mone Nobeoka1, Yusuke Kuwana1, Kohsuke Kamizaki1, Shizuka Arakawa1, Minoru Hayashi1, Takashi Yokogawa2,4,5, Chie Takemoto3, Ryota Yamagami1, Hiroyuki Hori1 (1. Graduate school of science and engineering, Ehime University, 2. Faculty of Engineering, Gifu University, 3. RIKEN, BDR, 4. Center for One Medicine Innovative Translational Research, Gifu University, 5. United Graduate School of Drug Discovery and Medical Information Sciences, Gifu University)
[3P-143]Roles of the lncRNA, mlonRNA molecules in fission yeast fbp1 gene activation
○Hana Oe1, Ryuta Asada2, Kouji Hirota1 (1. Department of Chemistry, Graduate school of science, Tokyo Metropolitan University, 2. Department of Viticulture and Enology, University of California, Davis, CA, USA.)
[3P-144(3AS-03-05)]Genome-wide N-terminally truncated novel protein isoform production triggered by springer, an RE escaped from piRNA system
○Mai Moritoh1, Toru Morita2, Chikara Takeuchi3, Yuka W. Iwasaki3, Mikiko C. Siomi1 (1. The University of Tokyo, 2. Sch. of Med., Yokohama City Univ., 3. IMS, RIKEN)
[3P-145]Integration of cis-regulatory elements from public databases
○Tomoe Nobusada1, Akira Hasegawa1, Scott Walker1, Nishad Thalhath1, Hideya Kawaji2, Takeya Kasukawa1 (1. RIKEN IMS, 2. Tokyo Metropolitan Institute of Medical Science)
[3P-146]Novel transcriptional regulation tools using Type I-D CRISPR-Cas for plants
○Kugo Goto1, Satoshi Kidokoro1, Naoki Wada2, Keishi Osakabe2, Yuriko Osakabe1 (1. Sch. of Life Sci. & Tech., Science Tokyo, 2. Grad. Sch. of Tech., Ind. & Soc. Sci., Tokushima Univ.)
[3P-147]The Importance of Suitable Reference Data for Improved Cell Type Annotation Prediction in Spatial Transcriptomics Samples
○Afeefa Zainab1, Alexis Vandenbon1,2 (1. Institute for Life and Medical Sciences, Kyoto University, , 2. Graduate School of Biostudies, Kyoto University, Japan)
[3P-148]Development of a visualization system for transcription initiation complexes in mitochondria
○Shigeru Matsuda1, Yukinori Nakamura1, Fanyan Wei1 (1. Tohoku Univ.)
[3P-149]Transcriptional regulation of the zinc efflux transporter by ribosomal protein RpmJ
○Riko Shirakawa1, Kazuya Ishikawa1, Kazuyuki Furuta1, Chikara Kaito1 (1. Grad. Sch. Med. Dent. Pharm., Okayama Univ)
[3P-150]Biochemical elucidation of novel bi-function in a xylan-responsive transcriptional regulator in Streptomyces sp. SirexAA-E
○Naoki Hayashi1, Keisuke Ohashi2, Tatsuya Nagano2, Keiichi Okimune2, Taichi Endo Takasuka1,2 (1. Graduate school of Agriculture, Hokkaido university, 2. Graduate School of Global food resources, Hokkaido university)
[3P-151]Interaction of beta-catenin with hypoxia-inducible factors
○Shun Takemoto1, Showa Komatsu1, Mebae Koike1, Kazuhiro Shiizaki1,2 (1. Grad. Sch. Life Sci., Toyo Univ., 2. Facl. Life Sci., Toyo Univ.)
[3P-152]Elucidation of the transcriptional regulatory mechanism of RNAPII in fertilized eggs
○Takashima Satsuki1, Mahiru Sugiura1, Koki Yamashita3, Shiho Nakano3, Hideto Matsushima3, Keigo Shimizu3, Satoshi Kurosaka4, Nakaya Masataka2, Mitani Tasuku1 (1. Department of Genetic Engineering, Faculty of Biology-Oriented Science and Technology, Kindai Univ. , 2. Shiga University of Medical Science, 3. Graduate School of Biology-Oriented Science and Technology, Kindai Univ. , 4. Institute of Advanced Technology, Kindai University)
[3P-153]The mechanism of G-quadruplex in retrotransposon LINE-1 regulates transcription
○Sunmin Lee1, Masaya Gessho1, Shinya Taniguchi1, Natsuki Kinoshita1, Takeru Torii1, Yoshiki Hashimoto1, Mituki Tsuruta1, Akito Nomoto1, Daisuke Miyoshi1, Keiko Kawauchi1 (1. Faculty of frontiers of Innovative Research in Science and Technology (FIRST), Konan University)
[3P-154]Functional analysis of phosphorylated CTD binding RNA methyltransferase factor PCIF1 in the stress response
○Chihiro Oyama1, Ryoya Kano1, Chihiro Ikeda1, Ai Sugita1, Hiroyasu Ishiguro1, Yoshiaki Tabuchi2, Aki Tanaka1, Yoshiaki Ohkuma3, Shinichiro Akichika4, Tsutomu Suzuki4, Yutaka Hirose1 (1. Grad. Sch. of Med. & Pharma. Sci., Univ. of Toyama, 2. Life Sci. Res. Center, Univ. of Toyama, 3. Grad. Sch. of Biomed. Sci., Nagasaki Univ., 4. Grad. Sch. of Eng., Univ. of Tokyo)
[3P-155]Comparative study of transactivational effects by epithelium specific ETS transcription factors on venom protein genes from Habu snake (Protobothrops flavoviridis).
○ZHAONAN WANG1, Yinrui Sun1, Hitomi Nakamura2, Naoko Oda-Ueda2, Hiroki Shibata1 (1. Genomics division, Medical Institute of Bioregulation, Kyushu university , 2. Department of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, Sojo University)
[3P-156]Transcription start sites and RNA stability of newborn genes that emerged during the diversification of Arabidopsis thaliana
○Takuya Nakagawa1, Yusei Shigematsu1, Takuto Nakatsuji2, Soichirou Satoh1,2 (1. Grad. Sch. Life Env. Sci., Kyoto Pref. Univ., 2. Fac. Sch. Life Env. Sci., Kyoto Pref. Univ.)
[3P-157]Novel Transcriptional Regulatory Mechanism of IQGAP3, an Adaptor Molecule Involved in Cancer Malignancy
○Shinya Taniguchi1, Masaya Gessho1, Sunmin Lee1, Ryosuke Suzuki1, Takeru Torii1, Mitsuki Turuta1, Daisuke Miyoshi1, Keiko Kawauchi1 (1. Konan Univ.)
[3P-158]Development of a tool to promote target gene translation via modified RISC
○Yusuke Nishida1, Hiro-oki Iwakawa1 (1. Rikkyo University)
[3P-159]Chaperone RNA inhibits aggregation of TDP43-related protein, a cause of amyotrophic lateral sclerosis (ALS)
○Ai Fujimoto1, Akira Kitamura2 (1. Hokkaido University Graduate School of Life Science, 2. Hokkaido Univ. Faculty of Advanced Life Science)
[3P-160(3AS-15-03)]Unbiased multi-omics analysis of splicing regulatory machinery with hareCLIP-seq
○Mina Yoshida1,2, Masahiko Ajiro1, Asuka Kawachi1, Mayumi Hanzawa1, Ryoichi Maenosono1, Takuya Izumi1, Minori Koizumi1, Natsuko Shinohara1, Marimu Sakumoto1, Hirotaka Matsui1, Shungo Adachi3, Rinshi Kasai4, Atsushi Iwama2, Genta Nagae5, Hiroki Ueda6, Hiroyuki Aburatani5, Akihide Yoshimi1 (1. Div. Cancer RNA Research, NCCRI, 2. Div. Stem Cell & Molecular Medicine, IMSUT, 3. Div. Proteomics, NCCRI, 4. Div. Advanced Bioimaging, NCCRI, Tokyo, Japan, 5. Genome Science & Medicine Laboratory, RCAST, Tokyo Univ., 6. Biological Data Science, RCAST, Tokyo Univ.)
[3P-161]MPsome-RNA Helicase Nexus Governs Mitochondrial RNA Biogenesis in Trypanosomes
○Takuma Suematsu1, Andres Vacas1, Clinton Yu2, Lan Huang2, Liye Zhang3, Inna Afasizheva1, Ruslan Afasizhev1 (1. Boston University, 2. University of California, Irvine, 3. Shanghai Tech University)
[3P-162]Quality evaluation of RNA analysis using the microchip electrophoresis
○Yuji Sogabe1 (1. Shimadzu Corporation)
[3P-163]A novel role for the DExD-box RNA helicase UAP56 in the nuclear export of spliceosomal U snRNA
○Ichiro Taniguchi1, Tetsuro Hirose1,2, Mutsuhito Ohno3 (1. FBS, Osaka Univ., 2. OTRI, Osaka Univ., 3. LiMe, Kyoto Univ.)
[3P-164]Study on pseudouridine modifications in transfer-messenger RNA of Thermus thermophilus
○Kyosuke Fukuda1, Mone Nobeoka1, Yusuke Kuwana1, Kohsuke Kamizaki1, Naruki Kataoka1, Ryota Yamagami1, Hiroyuki Hori1 (1. Ehime University)
[3P-165]Alternative splicing mechanisms of insulin receptor by L-ornithine
○Fumihiko Hakuno1, Mariko Isogai1, Mitani Nonoka1, Hiroki Nishi1,2, Sara Fukushima1, Takuhiro Kawakami1, Eri Matsumoto1, Wakana Sato1, Akihiro Ito2, Shin-Ichiro Takahashi1, Naoyuki Kataoka1 (1. Dep. Ani. Res. Sci., Grad. Sch. Agri. Life Sci., The Univ. of Tokyo, 2. Div. Life Sci., Grad. Sch. Sci. Eng., Saitama Univ.)
[3P-166]Functional analysis of NVL2-interacting protein CWF19L2 in the debranching of intron lariats
○Renta Oshima1, Ryuzo Yamazaki1, Keiichi Izumikawa1, Masami Nagahama1 (1. Meiji Pharmaceutical University)
[3P-167]Temporal dynamics of isoform switching regulate interferon-I response through alternative splicing in human B Cells
○Mahoko Ueda1, Jun Inamo2, Fuyuki Miya4, Mihoko Shimada3, Kensuke Yamaguchi5, Yuta Kochi1 (1. Department of Genomic Function and Diversity, Medical Research Institute, Tokyo Medical and Dental University, 2. Division of Rheumatology, University of Colorado School of Medicine, 3. National Center for Global Health and Medicine, 4. Center for Medical Genetics, Keio University School of Medicine, 5. Biomedical Engineering Research Innovation Center, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University)
[3P-168]Targets and functions of Ptbp1 liquid liquid phase separated aggregates in cardiomyocytes
○Tai Sada1,2, Wataru Kimura1,2 (1. RIKEN BDR, 2. Osaka university)
[3P-169]Modification of an aptamer targeting the VβBCC complex
○Haruka Yamamoto1, Kazuyuki Kumagai1, Keisuke Kamba2, Li Wan2, Masato Katahira2,3, Takashi Nagata2,3, Taiichi Sakamoto1 (1. Chiba Institute of Technology, 2. Institute of Advanced Energy, Kyoto University, 3. Graduate School of Energy Science, Kyoto University)
[3P-170]Preventing AUA codon mistranslation: the synergistic effects of two tRNA modifications in bacteria
○Tomoya Sonobe1, Takayuki Ohira1, Tsutomu Suzuki1 (1. Dept. of Chem. and Biotech., Grad. Sch. of Eng., Univ. of Tokyo)
[3P-171]Elucidation of alternative splicing mechanism for methyl-CpG binding protein 2
○Saya Oshizuki1, So Masaki1, Satoshi Tanaka1, Naoyuki Kataoka1 (1. The University of Tokyo)
[3P-172]Localization analysis of polychaetiod mRNA in the early Drosophila embryo
○Kotaro Kunitake1, Hideki Yoshida1 (1. Dept. of Appl. Biol., Kyoto Inst. of Technol.)
[3P-173]Domain Structure-Functional analyses of ZRSR2 protein, a causative gene product for Myelodysplastic Syndrome
○Tomoki Chiba1, Eri Matsumoto1, So Masaki1, Satoshi Tanaka1, Naoyuki Kataoka1 (1. The University of Tokyo)
[3P-174]Strong expression in rectal gland cells of C. elegans ROP-1 and Y RNA homologs
○Aoi Yamaguchi1, Takehiro Chiba2, Kyosuke Imaizumi1, Shahriar Rahman Shovon2, Shusei Sugita1, Chisato Ushida1,2 (1. Grad. Sch. of Agri. Life Sci., Hirosaki Univ., 2. UGAS, Iwate Univ.)
[3P-175]Investigation of the structure and interaction of an RNA aptamer targeting α-synuclein using NMR
○Xiang Li1,2, Yudai Yamaoki1,2, Omar Eladl1,2, Takashi Nagata1,2, Kazuma Murakami3, Masato Katahira1,2 (1. Institute of Advanced Energy, Kyoto University, 2. Graduate School of Energy Science, Kyoto University, 3. Graduate School of Agriculture, Kyoto University)
[3P-176]Identification and function of the polyA-adduct site in the YIPFα1A 3'UTR
○Ryusei Yamamoto1, Nobuhiro Nakamura1 (1. Graduate School of Kyoto Sangyo University)
[3P-177]Cryo-EM analysis of the novel RNA-guided recombinase
○Nami Shiojiri1, Naoto Nagahata1, Sae Okazaki2, Masahiro Hiraizumi1,2, Keitaro Yamashita1,2, Hiroshi Nishimasu1,2 (1. Dept. of Chem. & Biotech., Grad. Sch. of Eng., Univ. of Tokyo, 2. RCAST, Univ.of Tokyo)
[3P-178]Analysis of Emergent Sequence and Structural Features Driven by Cycles of Random RNA Ligation and Degradation
○Nozomi Adachi1,2, Nao Masuda3, Shohei Terazawa4, Kosuke Fujishima3,5 (1. Env.Info., Keio Univ., 2. Inst.Adv.Biosci., Keio Univ., 3. ELSI., Science Tokyo, 4. LST., Science Tokyo, 5. Grad.sch. of Media and Governance., Keio Univ.)
[3P-179]Analysis of Pathogenic Genes Expression by Novel sRNA Esr77 in Enterohemorrhagic Escherichia coli O157
○Tomoya Kaneko1, Ryota Sugimoto1, Sunao Iyoda2, Yasuhiko Sekine1 (1. Rikkyo University, 2. National Institute of Infectious Diseases)
[3P-180]Analysis of RNA Editing Characteristics of ADAR2 Using Synthetic Substrate RNAs
○Shun Shimauchi1, Naoki Shimazu1, Yuki Ogata1, Masatora Fukuda1,2 (1. Dept. Chem., Graduate School of Science, Fukuoka Univ, 2. Dept. Chem., Fac. Sci., Fukuoka Univ.)
[3P-181]Investigation of novel RNAi target genes and quantification of knockdown efficiency in Oryctes rhinoceros
○Ryuhei Kawamitsu1 (1. Hokkaido Univ.)
[3P-182]Cpeb4 regulates osteoclastogenesis and ovariectomy-induced bone loss via the stabilization of Fosl2 mRNA
○Tadayoshi Hayata Hayata1, Yasuhiro Arasaki1, Takuro Akiya1, Masamichi Li1, Yukihiro Kohara1, Yoshinori Asou2, Yoichi Ezura3,4 (1. Tokyo University of Science, 2. Institute of Science Tokyo, Orthopedic Surgery, 3. Institute of Science Tokyo, Joint Surgery and Sports Medicine, 4. Teikyo Heisei University)
[3P-183]Molecular basis of plant organelle C-to-U RNA editing
○Takamasa Teramoto1, Ryota Urushihara1, Reiya Aoyama1, Ayumi Okada1, Bernard Gutmann2, Ichinose Mizuho2, Yagi Yusuke2, Nakamura Takahiro1, kakuta Yoshimitsu1 (1. Kyushu Univ., 2. EditForce Inc.)
[3P-184]Functional analysis of the cold-inducible RNA-bindig protein Rbm3 in the liver of hibernating chipmunks
○Nene Sakabe1, Obo Kisae2, Okahara Manato2, Tamura Kei1,2, Ito Michihiko1,2, Matsuo Takuya1,2, Tsukamoto Daisuke1,2 (1. Grad. Sch. of Sci., Kitasato Univ., 2. Lab. of Mol. Bio., Sch. of Sci., Kitasato Univ.)
[3P-185]Comprehensive analysis of the LINE1-associated protein complexes reveals putative functional elements of LINE1 RNA
○Masahiro Onoguchi1,2, Shungo Adachi3, Michiaki Hamada1,2 (1. Waseda Univ., 2. AIST, 3. NCC)
[3P-186]Expression pathways of ribosome-binding proteins that suppress translational activity in Escherichia coli
○Hideji Yoshida1, Tomohiro Shimada2, Yasushi Maki1, Shou Furuike1 (1. Osaka Med. Pharm. Univ., 2. Meiji Univ.)
[3P-187]Analysis of the H. pylori ribosome under stress conditions
○Yasushi Maki1, Tomohiro Miyoshi2, Shou Furuike1, Hitomi Mimuro2, Hideji Yoshida1 (1. Osaka Med. Pharm. Univ., 2. Oita Univ., RCGLID)
[3P-188]Sperm-specific regulatory mechanism of translation by TCP11
○Taichi Shiraishi1, Kazuya Ichihara1, Sakurako Goto2, Takuhiro Ito2, Akinobu Matsumoto1 (1. Nagoya Univ., 2. RIKEN)
[3P-189]Distinct roles of translation factors eIF1A and eIF5B in regulating initiation step of Repeat Associated Non-AUG (RAN) translation
○Hayato Ito1, Kodai Machida2, Yoshitaka Nagai3, Hiroaki Imataka2, Hideki Taguchi1,4 (1. Science Tokyo, Sch. Life Sci. Tech., 2. Univ. of Hyogo, Dept. of Eng., 3. Kindai Univ., Med., 4. Science Tokyo, IIR)
[3P-190]Translation mechanism of abnormal pentapeptide repeat protein in spinocerebellar ataxia type 31.
○Yuki Aoki1, Kohji Mori1, Shoshin Akamine1, Ryota Uozumi1, Shiho Gotoh1, Tesshin Miyamoto1, Koujin Miura1, Shizuko Kondo1, Yuya Kawabe2, Sjinji Tagami2, Yoshitaka Nagai3, Manabu Ikeda1 (1. Osaka Univ., 2. Minoh Neuropsychiatric Sanatorium, 3. Kindai univ.)
[3P-191]Establishment of a method for the comprehensive identification of bona fide translation initiation sites
○Kazuya Ichihara1, Taichi Shiraishi1, Akinobu Matsumoto1 (1. Division of Biological Science, Graduate School of Science, Nagoya Univ.)
[3P-192]Analysis of a novel inhibitor against eukaryotes-specific translation
○Syotaro Noseda1, Kodai Machida1, Hiroaki Imataka1 (1. Dept. of Appl. Chem., Grad Sch. of Eng., Univ. of Hyogo)
[3P-193]The possibilities of the translational regulation related to the polyproline sequences and hypusinated eIF5A in Drosophila
○Hinako Uenishi1, Hideki Yoshida1 (1. Dept. of Appl. Biol., Kyoto Inst. of Technol.)
[3P-194]Reconstitution of wheat protein synthesis system
○Haruyuki Furukawa1, Yuto Nagashio1, Kensuke Tutsumi1, Kazuki Goto1, Takumi Nishioka1, Takumi Kondo1, Ryunosuke Watanabe1, Moe Fujii1, Ryohei Kato1, Chie Tomikawa1, Kazuyuki Takai1 (1. Graduate School of Science and Engineering, Ehime University)
[3P-195]Investigation of molecular mechanism of ATXN8OS (CUG) repeat-associated non-AUG translation
○Soyoka Sakamoto1, Hayato Ito1, Mayuka Hasumi1, Makito Hirano2, Yoshitaka Nagai2, Hideki Taguchi3,1 (1. School of Life Science and Technology, Institute of Science Tokyo, 2. Faculty of Medicine, KINDAI UNIVERSITY, 3. Institute of Innovative Research, Institute of Science Tokyo)
[3P-196]Functional analysis of the length of ewsr1b mRNA 3' UTR and the Ewsr1b in translational regulation during zebrafish early development
○Keisuke Sato1, Ludivine Fierro1, Tomoya Kotani1,2 (1. Graduate School of Life Science, Hokkaido Univ., 2. Faculty of Science, Hokkaido Univ.)
[3P-197]Evaluation of intracellular stability of human microproteins encoded in 5’UTRs.
○Hinata Hashimoto1, Taichi Akase1, Yasunori Aizawa1,2 (1. Science Tokyo, 2. KISTEC)
[3P-198]Ubiquitination of eukaryotic elongation factor eEF1A.
○Nana Kobayashi1, Yasuyuki Iwasa1, Naoto Yokota1, Hiroyuki Kawahara1 (1. Tokyo Metropolitan Univ.)
[3P-199]Mechanistic insights into translational regulation during mammalian spermatogenesis
○Yuka Isono1, Hideto Tanaka, Heita Maeda1, Shin-ichi Kashiwabara1 (1. Institute of Life and Environmental Sciences, University of Tsukuba)
[3P-200]Anota2seqUtils for identification and integration of cis-acting factors underlying post-transcriptional regulation of gene expression
Krzysztof Jan Szkop1, Kathleen Watt1, Kiana Hosseinpour Moghaddam1, Johannes Ristau1, Arash Darzian Rostami1, Alana Panzenhagen1, Christian Oertlin1, Inci Sevval Aksoylu1, Valentina Gandin2, Shannon Mclaughlan1, Marie Cargnello2, HaEun Kim2, Matthew Leibovitch2, Shan Chen1, Luc Furic3,4, Ivan Topisirovic2, ○Ola Larsson1 (1. Karolinska Institute, 2. McGill University, 3. Monash University, 4. Peter MacCallum Cancer Centre)
[3P-201]Structural insights into translation inhibition independent of E. coli RNase I-mediated ribosomal RNA degradation
○Takehito Tanzawa1, Atsushi Minami2, Hideji Yoshida3, Tetsuhiro Ogawa2, Takayuki Kato1 (1. Osaka Univ., 2. Univ. of Tokyo, 3. Osaka Med. Pharm. Univ.)
[3P-202]Functional Analysis of Chloroplast Ribosome Hibernation Protein PSRP1 in Light and Darkness
○Yusuke Yoshizawa1, Kenta Tanaka1, Yasuhiko Sekine1 (1. Rikkyo University)
[3P-203]The regulation of miRISC activity by phosphorylation of Argonaute protein.
○Tomosuke Sakaguchi1, Takumi Tomohiro1, Akira Fukao1, Yoshinori Funakami1, Toshinobu Fujiwara1 (1. Kindai University)
[3P-204]RNA-binding protein ZFP36L1 coordinates mRNA degradation and translational repression.
○Masayuki Fukuda1, Takumi Tomohiro1, Akira Fukao1, Yoshinori Funakami1, Fujiwara Toshinobu1 (1. Kindai University)
[3P-205]Prediction of disease-associated GPCR interaction pairs
○Wataru Nemoto1,2, Aoi Fukushima2, Teruse Hiroaki3, Arina Ouma1, Hiroyuki Toh3 (1. Div. Life Sci., Dept. Sch. & Eng., Tokyo Denki Univ., 2. Life Sci., Grad. Sch. & Eng., Tokyo Denki Univ., 3. Bio Sci., Scho. of Biol. & Env. Sci., Kwansei Gakuin Univ.)
[3P-206]Computational analysis of OPRD1-OPRM1 heterodimer ligands and their binding residues
○Ryota Takishima1, Wataru Nemoto1,2 (1. Life Sci. & Eng., Grad. Sch., Sci. & Eng., Tokyo Denki Univ. , 2. Div. Life Sci., Dept. Sch. & Eng., Tokyo Denki Univ.)
[3P-207]Development of a method to predict interaction pairs between membrane proteins
○Hiroto Narushima1, Gunji Takuma1, Aoi Fukushima2, Wataru Nemoto1,2 (1. Div. Life Sci., Dept. Sch. & Eng., Tokyo Denki Univ., 2. Life Sci. & Eng., Grad. Sch., Sci. & Eng., Tokyo Denki Univ.)
[3P-208]CCL8-mediated crosstalk between endothelial colony-forming cells and TNBC promotes invasion and tumorigenicity
○HEMANI BHATIA1, Jiwoo Jeong1, Eun-Sook Kim1, Hyun Kyung Lim1, Hyunsook Lee1, Kyu-Tae Kang1, Joohee Jung1, Aree Moon1 (1. DUKSUNG WOMEN'S UNIVERSITY)
[3P-209(3PS-01-03)]How centromeric RNA regulates chromosomal segregation
○Saho Matsui1,2, Ryusuke Nozawa1, Anna Suzuki1,2, Toru Hirota1,2 (1. Div. Exp. Pathol. Cancer Inst. JFCR, 2. Dept. JFCR., Tokyo Med. & Dent. Univ.)
[3P-210(3PS-15-07)]DJ-1, a Parkinson's disease-associated factor, detoxifies cPGA for cytoprotection.
○Shizuka Ogiwara1, Hidetaka Kosako2, Aiko Watanabe1, Fumika Koyano1, Koji Yamano1, Noriyuki matsuda1 (1. Medical Research Institute, Tokyo Medical and Dental Univ., 2. Institute of Advanced Medical Sciences, Tokushima Univ.)
[3P-211]Studies on the aggregation properties and cytotoxicity of L13R mutant insulin
○Yuki Yamanaka1, Hiroyuki Kawahara1 (1. Tokyo Metropolitan University)
[3P-212]Structure of V-ATPase with the inhibitor and in situ structural analysis
○Fuka Ueda1, Yui Nishida1, Atsuki Nakano1, Atsuko Nakanishi2, Kaoru Mitsuoka3, Ken Yokoyama1 (1. Grad.Sch. Life Sci., Kyoto Sangyo Univ., 2. IPR, Osaka Univ., 3. Research Center for Ultra-High Voltage Electron Microscopy, Osaka Univ.)
[3P-213]Nanopore Sensing to Reveal the Membrane Translocation Mechanism of a Binary Toxin.
○Yuki Mitani1, Sotaro Takiguchi2, Ryuji Kawano2, Hideaki Tsuge1 (1. Fac. of Life Sci., Kyoto Sangyo Univ, 2. Grad. Sch. Eng., Tokyo Univ. Agric. Technol.)
[3P-214]The Impact of post-translational modifications on DNA interactions of Mycobacterium tuberculosis dormancy-inducing protein MDP1 observed by high-speed AFM
○Kaho Nakamoto1, Kenichi Umeda2, Akihito Nishiyama3, Yutaka Yoshida3, Sohkichi Matsumoto3, Noriyuki Kodera2 (1. Grad. Sch.Math. & Phys., Kanazawa Univ., 2. WPI-NanoLSI, Kanazawa Univ., 3. Dept. Bacteriol., Niigata Univ. Sch. Med.)
[3P-215]Elucidation of the factors responsible for the decrease of MBNL1 protein in in a Cellular Model of Myotonic Dystrophy Type 1
○Yoshitaka Aoki1, Ai Ohki1, Motoaki Yanaizu1, Yoshihiro Kino1 (1. Department of RNA Pathobiology and Therapeutics, Meiji Pharmaceutical University)
[3P-216]Large-scale development of kinase-specific artificial substrate peptides
○Junqi Liang1, Junna Nakazono1, Mao Uehara1, Dai Sakamoto1, Naoyuki Sugiyama1,3, Yasushi Ishihama1,2 (1. Kyoto University, 2. 2)National Institute of Biomedical Innovation, Health and Nutrition, 3. Omics Research Center, National Cerebral and Cardiovascular Center)
[3P-217]Structural and functional analysis of antiviral protein derived from Mirabilis jalapa
○Nanami Nishida1, Noriyuki Habuka1, Hideaki Tsuge1 (1. Kyoto Sangyo University)
[3P-218(3AS-04-01)]Development of the AlissAID System: An Inducible Protein Degradation System Using Single Peptide Antibodies
○Kohei Nishimura1, Yoshitaka Ogawa1, Keisuke Obara1, Takumi Kamura1 (1. Nagoya Univ.)
[3P-219]Investigation of structural dynamics of E6AP/E6/p53 complex and mechanisms of p53 ubiquitination by using HS-AFM and biochemical approach
○Soma Yamamoto1, Kazusa Takeda1, Holger Flechsig2, Hiroki Konno2 (1. College of Science and Engineering, School of Biological Science and Technology, Kanazawa University, 2. WPI Nano Life Science Institute (WPI-NanoLSI), Kanazawa University)
[3P-220]Phosphorylation of lipid-metabolizing enzyme DDHD1 is regulated by multiple kinases and phosphatases
○Naoki Matsumoto1, Yuto Sugiyama1, Kokoro Tominaga1, Kyohei Hara1, Katsuyuki Satake1, Yoko Nemoto-Sasaki1, Atsushi Yamashita1 (1. Dept. of Biol. Chem., Fac. of Pharm. Sci., Teikyo Univ.)
[3P-221]Verification of protein-protein interaction between peroxiredoxin 2 and sorting nexin 10
○Tomoki Hara1, Hiroki Konno2 (1. Grad. Sch. of Front. Sci. Init. Kanazawa Univ. , 2. WPI Nano Life Sci. Inst. Kanazawa Univ.)
[3P-222]Development of Single cell- drug screening by Native mass spectrometry
○Noa Suzuki1, Waka Sakamoto1, Tsuyoshi Konuma1, Satoko Akashi1 (1. Graduate School of Medical Life Science, Yokohama city university)
[3P-223]The discovery of the ion-pumping acceleration pigment of microbial rhodopsin
○Takayoshi Fujiwara1,2, Masumi Hasegawa3, Yosuke Nishimura4, Kaho Mori1,2, Shinichi Takaichi5, Keiichi Inoue2,6, Susumu Yoshizawa1,2 (1. The university of Tokyo・Atmosphere and Ocean research Institute, 2. The university of Tokyo・Graduate School of Frontier Sciences, 3. Japan Agency for Marine-Earth Science and Technology・Institute for Extra-cutting-edge Science and Technology Avant-garde Research, 4. Japan Agency for Marine-Earth Science and Technology・Research Center for Bioscience and Nanoscience, 5. Tokyo University of Agriculture・Faculty of Life Sciences, 6. The university of Tokyo・The institute for solid state physics)
[3P-224]Ultra-deep single-cell proteomic analysis of patient-derived glioblastoma cells
○Hiroko Kozuka-Hata1, Tomoko Hiroki1, Aya Kitamura1, Naoaki Miyamura1, Tetsu Akiyama2, Jun-ichiro Inoue3, Kouhei Tsumoto1,4, Masaaki Oyama1 (1. Med. Proteomics Lab., Inst. of Med. Sci., Univ. of Tokyo, 2. Lab. of Mol. Gen. Info., IQB, Univ. of Tokyo, 3. UTOPIA, 4. Dept. of Bioeng., Grad. Sch. of Eng., Univ. of Tokyo)
[3P-225]Functional analysis and substrate identification of the DCAF family protein DCAF3
○Yumi Mikura1,2, Kohei Nishino3, Hidetaka Kosako3, Tatsuya Sawasaki1, Satoshi Yamanaka1,2 (1. Division of Cell-Free Life Sciences, Proteo-Science Center, Ehime University (Div. Cell-Free Sci., PROS, Ehime Univ.), 2. Division of Proteo-interactome, Proteo-Science Center, Ehime University (Div. Proteo-interactome, PROS, Ehime Univ.), 3. Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University (Inst. Adv. Med. Sci., Tokushima Univ.))
[3P-226]Functional analysis of the DCAF family protein COP1 for development of protein degrader
○Kenshi Tanaka1,2, Kohei Nishino3, Hidetaka Kosako3, Tatsuya Sawasaki1, Satoshi Yamanaka1,2 (1. Division of Cell-Free Life Sciences, Proteo-Science Center, Ehime University, 2. Division of Proteo-interactome, Proteo-Science Center, Ehime University, 3. Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University)
[3P-227]Introduction and examples of structural analysis for cryo-electron microscopy utilizing EG-grid; Functional Grid
○Hiroki Tanino1, Tsuyoshi Inoue1 (1. Osaka University)
[3P-228]Molecular dynamics study to investigate how additives alter protein structural stability
○Hitomi Baba1, Mafumi Hishida2, Yoshiki Ishii3, Go Watanabe1,3,4 (1. Grad. Sch. of Sci., Kitasato Univ., 2. Sch. of Sci., Tokyo Univ. Sci., 3. Sch. of Front. Eng., Kitasato Univ., 4. KISTEC)
[3P-229]Analysis of the proton release mechanism of light-driven rhodopsin RxR using solution NMR spectroscopy
○Reika Hironishi1, Toshio Nagashima2, Rika Suzuki1, Masafumi Hirohata1, Keiichi Kojima3, Toshio Yamazaki2, Yuki Sudo3, Hideo Takahashi1 (1. Grad. Sch. of Med. Life Sci., YCU, 2. BDR, RIKEN, 3. Grad. Sch. of Med., Dent. and Pharma. Sci., Univ. of Okayama)
[3P-230]Structural analysis of human aquaporin-8 using single-particle cryo-electron microscopy
○Yukihiro Tanimura1, Shota Suzuki1, Akiko Kamegawa1, Kouki Nishikawa2, Yoshinori Fujiyoshi1 (1. CeSPL, TMDU, 2. Adv. Biomol. Char., TUAT)
[3P-231]Substrate-binding structure of a microbial amino acid transporter revealed by cryo-electron microscopy single-particle structure analysis
○KEI NANATANI1,2,3, Ryo Kanno4, Takeshi Kawabata5, Satoshi Watanabe6, Takeshi Yamanaka3, Akari Miyamoto3, Masafumi Hidaka3, Satoshi Ogasawara7, Takeshi Murata7, Kenji Inaba6, Lan Guan8, Kaoru Mitsuoka9, Keietsu Abe3, Masayuki Yamamoto1,2, Seizo Koshiba1,2 (1. Tohoku Univ., INGEM, 2. Tohoku Univ., ToMMo, 3. Tohoku Univ. Grad. Sch. Agr., 4. OIST, 5. Tohoku Univ., Grad. Sch. Info., 6. Kyushu Univ., Med. Ins. Bio., 7. Chiba Univ., Grad. Sch. Sci., 8. Texas Tech Univ., HSC, 9. Osaka Univ., UHVEM)
[3P-232]Elucidation of the biochemical significance of histidine methylation in glycolytic enzyme γ-enolase.
○Fumiya Kasai1, Koichiro Kako2, Yuan Yao3, Akiyoshi Fukamizu4 (1. Univ. of Tsukuba, Life and Agri. Sci., 2. Univ. of Tsukuba, Life and Env. Sci., 3. Univ. of Tsukuba, Human Biol., 4. Univ. of Tsukuba, TARA center)
[3P-233]Molecular Mechanisms of Improvement of Cold Tolerance of Animals by Ice-Binding Proteins
○Saki Nakamura1, Ryohei Kuriyama1, Daiki Shimose1, Yoichi Shinkai2, Katsuhiro Kusaka3, Yuka Ikemoto4, Masahiro Kuramochi1 (1. Graduate School of Science and Engineering, Ibaraki Univ., 2. Biomedical Research Institute, AIST, 3. CROSS, 4. JASRI)
[3P-234]Analysis of the functional structure of the actin-binding protein Abitram
○Yuki Hoshikawa1, Misaki Domoto1, Kentaro Noi2, Kyosuke Shinohara1 (1. Tokyo University of Agriculture and Technology, 2. Kobe University)
[3P-235]Comprehensive analysis of the effects of missense variants on the antibody-drug target proteins upon the binding affinity
○Keiichiro Murayama1, Atsushi Hijikata2 (1. Grad. Sch. of Life Sci., Tokyo Univ. of Pharm. and Life Sci., 2. Tokyo Univ. of Pharm. and Life Sci.)
[3P-236]Development of Genetically Modified Baculoviruses Capable of Inactivation in the Silkworm-Baculovirus Expression System
○Misaki Shibuya1, Takeru Ebihara1, Hiroaki Mon2, Jaeman Lee2, Akitsu Masuda2, Masato Hino2, Ryosuke Fujita2, Takahiro Kusakabe2 (1. Grad. Sch. of Biores. Bioenv. Sci., Univ. of Kyushu, 2. Fac. Agr., Univ. of Kyushu)
[3P-237]X-ray crystallography of a Mycobacterium tuberculosis growth regulator in complex with interacting factors
○Kengo Matsu1, Toki Arai1, Yuuka Kawanobe1, Kodai Kamba1, Akihito Nishiyama2, Yuriko Ozeki2, Sohkichi Matsumoto2, Kosuke Ito1 (1. Grad. Sch. of Sci. and Tech., Niigata Univ, 2. Grad. Sch. of Medical and Dental Sci., Niigata Univ)
[3P-238]Elucidation of novel arrest peptide CliM from Clostridium genus
○Mayu Yoshida1, Keigo Fujiwara2, Hiraku Takada3, Shinobu Chiba1 (1. KyotoSangyoUniversity, 2. The National Institute of Genetics, 3. TOYAMA Prefectural University)
[3P-239]Reaction characteristics of sesamin oxidizing CYP enzymes during seed development and germination
○Erisa Harada1, Jun Murata1, Akira Shiraishi1, Hiromi Toyonaga1, Eiichiro Ono2, Masayuki P. Yamamoto3, Manabu Horikawa1 (1. Suntory Found. for Life Sci., 2. Suntory Global Innov. Center Ltd., 3. Grad. Sch. of Sci. and Eng., Univ. of Toyama)
[3P-240]Identification of archaea DTK motif rhodopsin clades from marine metagenome data
○Kaede Wakabayashi1, Tae Kumagai1, Fumio Hayashi2, Takashi Kikukawa3, Takafumi Shimoaka1, Kazutoshi Yoshitake4, Takashi Gojobori5, Masaharu Kawauchi6, Minami Matsui6, Yuko Makita7, Masashi Sonoyama1,8,9 (1. Grad Sch. Sci. Tech., Gunma Univ., 2. Ctr. Inst. Analysis., Gunma Univ., 3. Fac. Adv. Life. Sci., Hokkaido Univ., 4. Kitasato Univ., 5. MaOI Inst., 6. RIKEN, CSRS, 7. Maebashi Inst. Tech., 8. GIAR, Gunma Univ., 9. GUCFW , Gunma Univ.)
[3P-241]Predicting structural information of amyloid fibrils using AlphaFold2
○Miu Ekari1, Sekiyama Naotaka1, Tochio Hidehito1 (1. Kyoto Univ.)
[3P-242]Recognition of quadruplex nucleic acids by a novel quadruplex nucleic acid-binding protein RBM22
○Kei Matsuo1, Kai Ohmori1, Hidetaka Torigoe1 (1. Tokyo University of Science)
[3P-243]Spectroscopic analysis of the carotenoid effect bound as a light-harvesting antenna
○Shota Itakura1, Yosuke Mizuno1, Kota Katayama1,2, Rei Abe-Yoshizumi1, Gali Tzlil3, Ariel Chazan3, Oded Béjà3, Hideki Kandori1,2 (1. Grad. Sch. of Eng., NIT , 2. OBTRC, NIT, 3. Technion-Israel Inst. Tech.)
[3P-244]Zinc Dependence in the Membrane Transport of Olfactory Receptors by RTP1S
○Chikako Tonoki1, Ryosuke Inoue2, Kyosuke Shinohara1,2, Masafumi Yohda1,2, Yosuke Fukutani1,2 (1. Dept. of Biotechnol. Tokyo Univ. of Agric. and Technol., 2. Dept. of Biotechnol. Tokyo Univ. of Agric. and Technol.,)
[3P-245(3AS-05-07)]Synthesis and Understanding of Cell-Derived Vesicles
○Eisuke Kanao1,2, Koshi Imami3, Yoshihiro Sasaki4, Jun Adachi1,2, Yashishi Ishihama1,2 (1. Kyoto Univ. Grad. Pharm., 2. NIBIOHN, 3. RIKEN IMS, 4. Kyoto Univ. Grad. Eng.)
[3P-246]Identification of key amino acid residues for functional expression of TAAR5
○Hiroto Koguma1, Mei Saitou2, Kyosuke Shinohara1,2, Masahumi Yohda1,2, Yosuke Fukutani1,2 (1. Dept. of Biotechnol. Tokyo Univ. of Agric. and Technol., 2. Dept. of Biotechnol. Tokyo Univ. of Agric. and Technol.,)
[3P-247]Verification of the conservation of a novel interaction between the general transcription/nucleotide excision repair factor TFIIH and RNA polymerases
○Masahiko Okuda1, Yoshifumi Nishimura1 (1. Yokohama City University)
[3P-248]Cryptic site prediction based on spatial distribution of disease associated missense variants
Chie Motono1,2, Hrumi Kagiwada1, Jun Koseki1, Atsushi Hijikata3, ○Kenichiro Imai1,4 (1. CMB, AIST, 2. CBBD-OIL, AIST, 3. Sch.Life Sci., Tokyo Univ. Pharm. Life Sci., 4. G-QuAT, AIST)
[3P-249]Exploration of scaffold protein nanoparticles for the development of antigen-presenting nanoparticle vaccines using silkworm baculovirus expression system (2).
○yuuki kawai1, akitsu masuda2, Jaeman Lee2, Mon Hiroaki2, Takahiro Kusakabe2 (1. Grad. Sch. of Biores. Bioenv. Sci., Univ. of Kyushu, 2. Fac. Agr., Univ. of Kyushu)
[3P-250]The βαβ motif at the origin of folded protein structures
○Andre Lecona Buttelli1, Eric Smith1,2,3, Liam M. Longo1,4 (1. Earth-Life Science Institute, Tokyo Institute of Technology, 2. Center for the Origin of Life, Georgia Institute of Technology, 3. Santa Fe Institute, 4. Blue Marble Space Institute of Science, Seattle Washington)
[3P-251]Improved substrate specificity of glycine oxidase based on predicted structures of substrate entrances.
○Hitomi Taneda1, Yoshiaki Nishiya1 (1. Div. of Life Sci., Grad. Sch. of Sci. and Eng., Setsunan Univ.)
[3P-252]Study on Binding of Ligand-Protein Using Deep Learning Methods
○Zhizhen Xu1, Jian Yu2, Toyoyuki Ose3, Min Yao3 (1. Graduate School of Life Science, Hokkaido Univ., 2. Institute for Protein Research, Osaka Univ., 3. Faculty of Advanced Life Science, Hokkaido Univ.)
[3P-253]Design of dual PDZ domain inhibitor for the development of anti-coronavirus drugs
○Natsuno Ando1, Takeshi Tenno1,5, Ryusei Hamajima1, Haruka Takagi1, Yuya Hanazono2, Nobutaka Numoto3, Youichi Suzuki4, Nobutoshi Ito2, Hidekazu Hiroaki1,5,6 (1. Grad. Sch. Pharm. Sci., Nagoya Univ., 2. Med. Res. Inst., Tokyo. Med. Dent. Univ., 3. Res. Inst. Int. Sci., Okayama Univ., 4. Grad. Sch. Med., Osaka. Med. Pharm. Univ., 5. BeCellbar, LLC, 6. NU-COMIT)
[3P-254]Investigation and characterization of purification conditions for norovirus VP1, which is insoluble due to overexpression
○Yuto Tsurumi1, Akitsu Masuda1, Lee Jae Man1, Hiroaki Mon1, Takahiro Kusakabe1 (1. kyushu university)
[3P-255]Structure-function studies of GPR84
○Shota Suzuki1, Kouki Nishikawa2, Hiroshi Suzuki1, Yoshinori Fujiyoshi1 (1. Adv. Res. Inst., Tokyo Med and Dent Univ, 2. Joint Res. Crs. Adv. Biomol. Character., Tokyo Univ. Agri. and Tech)
[3P-256]LC-MS based Comprehensive functional characterization of aminotransferases for the construction of nitrogen metabolic network in E. coli
○Shogo Hataya1, Sora Fukui2, Kaan Koper3, Sebastian Huss4, Zoran Nikoloski4, Hiroshi A Maeda3, Taichi E Takasuka1,2 (1. Grad. School of GFR, Hokkaido Univ. , 2. Grad. School of Agriculture, Hokkaido Univ., 3. University of Wisconsin-Madison, 4. Max Planck Institute of Molecular Plant Physiology)
[3P-257]Controlling the Physical Properties of Artificial Spider Silk Using Sequence-Property Relationships of Dragline Silk of Spiders
○Hiroyuki Nakamura1,2,3, Yusuke Ito3, Ryota Sato3, Hongfang Chi3, Chikako Sato3, Yasuha Watanabe1, Kazuharu Arakawa1,2,4 (1. Institute for Advanced Biosciences, Keio University, 2. Graduate School of Media and Governance, Keio University, 3. Spiber Inc., 4. Faculty of Environment and Information Studies, Keio University)
[3P-258]Analysis of calpain expression in mdm mice with a deletion mutation in N2A titin
○Yuzuru Ito1,2, Naoko Doi2, Aya Noguchi2, Shoji Hata2, Takehiro Tsukada1, Yasuko Ono2 (1. Toho Univ., 2. TMiMS)
[3P-259]Theoretical conformational analysis of the sodium channel SCN5A K817E mutation
○Haruyuki Kataguchi1, Mika Ohta1,2,3,4, Aki Sugano1,3,5, Toshihide Tabata6, Yutaka Takaoka1,2,3,4 (1. Data Science Center for Medicine and Hospital Management, Toyama University Hospital, 2. Department of Computational Drug Design and Mathematical Medicine, Toyama University Graduate School of Medicine and Pharmaceutical Sciences, 3. Department of Medical Systems, Kobe University Graduate School of Medicine, 4. Department of Health Science, Kobe Tokiwa University, 5. Center for Clinical and Translational Research, Toyama University Hospital, 6. Faculty of Engineering, University of Toyama)
[3P-260]Comparative functional expression of orthologs of the aldehyde-responsive odorant receptor OR6B1 in heterologous cells
○Haruto Kudo1, Reina Kanemaki1, Masafumi Yohda1, Yosuke Fukutani1 (1. Dept. Biotech., Grad. Sch. Eng., Tokyo Univ. Agric.)
[3P-261]Binding and structural changes between human Adenylyl cyclase9 and Gαs
○Risa Nomura1, Shota Suzuki1, Koki Nishikawa2, Hiroshi Suzuki3, Yoshinori Fujiyoshi1 (1. Tokyo Medical and Dental University, 2. Tokyo University of Agriculture and Technology, 3. CHUGAI PHARMACEUTICAL CO., LTD.)
[3P-262]Functional regulation of DNA helicase RTEL1 via ubiquitination
○Kosuke Matsuo1, Remi Tameda1, Hidefumi Iwashita1, Yusuke Sanada2, Shinsuke Ito3, Isao Kuraoka1, Arato Takedachi1 (1. Dpt of Biochem, Grad. Sch. of Sci, Fukuoka Univ, 2. Dpt of Physchem, Faculty of Sci, Fukuoka Univ, 3. RIKEN IMS)
[3P-263]Directed evolution of phosphite oxidation activity of Escherichia coli alkaline phosphatase
○Haruka Nihei1, Takahiro Seki2, Daisuke Umeno1 (1. Sch. Adv. Sci. Eng., Waseda Univ., 2. Waseda Res. Inst. Sci. Eng.)
[3P-264]Structural analysis of ATP synthase on the E. coli inversion membrane
○Kohei Kusaoka1, Atsuki Nakano1, Kaoru Mitsuoka2, Ken Yokoyama1 (1. Kyoto Sangyo University, 2. Osaka University)
[3P-265]Biochemical and structural studies of IMPDH2 proteins to gain insights into the biological significance of filament formation.
○Michelle Jane Clemeno Genoveso1, Akane Saito1, Miki Senda1, Koh Takeuchi2, Toshiya Senda1 (1. Structural Biology Research Center, Institute of Materials Structure Science, High Energy Accelerator Research Organization, 2. Department of Biophysical Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo)
[3P-266]Association mechanism of the cleavage sites in the APP116 ,and alpha- / beta- secretases which include the transmembrane domains.
○Ryo Fujimoto1, Seina Saito2, Naoyuki Miyashita1,2 (1. Grad. Sch. BOST, Kindai Univ., 2. BOST Kindai Univ.)
[3P-267]Interaction analysis of the C-terminal intrinsically disordered region of Mycobacterial DNA-binding protein 1 (MDP1) with small compounds by using NMR.
○Ayaka Asai1, Natsuko Goda1, Takeshi Tenno1,2, Emi Hibino1, Akihito Nishiyama3, Kosuke Ito4, Sohkichi Matsumoto4, Hidekazu Hiroaki1,2,5 (1. Grad. School of Pharm. Sci., Nagoya univ., 2. BeCellBar, 3. Grad. School of Med and Dent Sci., Niigata univ., 4. Grad. School of Sci and Tech., Niigata univ., 5. NU-COMIT)
[3P-268]The effect of hydrogen bond patterns on Cα distances between adjacent strands in β-sheets
○Hiromi Suzuki1 (1. Meiji Univ.)
[3P-269]Regulatory mechanisms of the stability of budding yeast Sec4 gene products
○Haruka Ota1, Hiroyuki Kawahara1 (1. Tokyo Metropolitan Univ.)
[3P-270]Highly efficient fluorescent probe to visualize protein interactions at the super-resolution
○Yuki Aono1, Takahiro Nakajima2, Wataru Ichimiya1, Mayumi Yoshida1, Sato Moritoshi1,2 (1. Graduate school of Arts and Sciences, The University of Tokyo, 2. Kanagawa Institute of Industrial Science and Technology)
[3P-271]Analysis of the function and structure of the clock-related protein SasA
○Sota Suzuki1, Takayoshi Koyano2, Takahiro Iida2, Risa Mutoh2 (1. Grad of sci Toho Univ., 2. Fac of sci Toho Univ.)
[3P-272]High-order structure of DNA by chemically modified DNA-binding proteins
Natsuno Hatano1, Mao Fukuyama2, ○Fumiaki Tomoike1 (1. Hokkai-Gakuen Univ., 2. Tohoku Univ.)
[3P-273]Interstrain and intertissue expression of the mitochondrial electron transfer system Complex IV subunit protein in mice.
○Tomoya Sugiyama1 (1. Graduate School of Engineering Science, Yokohama National University)
[3P-274]Structural basis of hydrolase MepS recognizing by adaptor NlpI
Shen Wang1, Chun-Hsiang Huang2, Te-Sheng Lin1, Chung-I Chang3, ○Shiou-Ru Tzeng1 (1. Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei, Taiwan, 2. Protein Diffraction Group, Experimental Facility Division, National Synchrotron Radiation Research Center, Hsinchu, Taiwan, 3. Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan)
[3P-275]Exploration of peptide probes for ultra-sensitive detection of isovaleric acid
○Kae Senoo1, Yukari Hataoka2, Shogo Saito1, Mina Okochi1 (1. Institute of Science Tokyo, 2. Shimadzu Corporation)
[3P-276]Molecular dynamics of mitochondrial inner membrane protein OPA1 using high-speed atomic force microscopy
○Yuta Imai1, Nanako Kobayashi1, Keitaro Umezawa2, Noriyuki Kodera3, Yuhei Araiso1 (1. Kanazawa Univ. Dept. of Clin. Lab. Sci., Div. of Health Sci., 2. Tokyo Metropolitan Institute for Geriatrics and Gerontology, 3. Kanazawa Univ. WPI Nano LSI)
[3P-277]Noninvasive Bioluminescence Imaging of Serum Albumins in Living Mice
○Sung Bae Kim1, Genta Kamiya2, Shojiro A Maki2 (1. AIST, 2. UEC)
[3P-278]Exploring unexplored sequence diversity in highly conserved phosphate-binding motifs
○Koh Seya1, Shohei Terazawa1, Liam M Longo2, Kosuke Fujishima2,3 (1. LST.,Science Tokyo, 2. ELSI.,Science Tokyo., 3. Grad.sch. of Media and Governance., Keio Univ.)
[3P-279]Structural basis for the maintenance of Golgi Ca2+ homeostasis via the Ca2+ pump SPCA1a
○TAIYUAN KU1,2, Satoshi Watanabe3, Zhenghao Chen1,2, Ken Inaba2,3,4 (1. Graduate School of Life Sciences, Tohoku University, 2. Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 3. Medical Institute of Bioregulation, Kyushu University, 4. Japan Agency for Medical Research and Development)
[3P-280]Structural analysis of adenosine A2A receptor bound to allosteric modulators
○Shota Nakamura1,2, Mika Hirose2, Tsuyoshi Saito3, Takayuki Kato2, Ryoji Suno4 (1. Graduate School of Frontier Bioscience, Osaka University, 2. Institute for Protein Research, Osaka University, 3. International Institute for Integrative Sleep Medicine, Tsukuba University, 4. Department of Medical Chemistry, Kansai Medical University)
[3P-281]Alterations in Signaling Mediated by Disease-Associated GPCR-GPCR Interaction Pairs
○Arina Ouma1, Aoi Fukushima2, Hiroyuki Toh3, Wataru Nemoto1,2 (1. Dept. Sci. & Eng., Tokyo Denki Univ., 2. Grad. Sci. & Eng., Tokyo Denki Univ., 3. Dept. Life. & Env., Kwanseigakuin Univ.)
[3P-282]Capturing metamorphic conformational changes between DPBB/DZBB structure: implication to early protein evolution
○Yui Tanaka1, Sota Yagi2,3, Shunsuke Tagami2,4,5, Kosuke Fujishima6,7 (1. LST., Science Tokyo, 2. RIKEN Center for Biosystems Dynamics Research, 3. Faculty of Human Sciences, Waseda University., 4. Graduate School of Medicine, Science and Technology, Shinshu University, 5. International Institute for Sustainability with Knotted Chiral Meta Matter (WPI-SKCM²), 6. ELSI., Science Tokyo, 7. Grad.sch. of Media and Governance., Keio Univ.)
[3P-283]A study on linear B cell epitope prediction based on local feature extraction of PSSM
○Chisato Matsui1, Keisuke Tanaka1, Yoichi Murakami1 (1. Department of Information Science, Faculty of Information Sciences, Tokyo University of Information Sciences)
[3P-284]Structural comparison of protein-protein interaction sites on the AlphaFold2 model structures and the natural structures
○Kaichi Ri1, Keisuke Tanaka2, Yoichi Murakami2 (1. Graduate School of Informatics, Tokyo University of Information Sciences, 2. Department of Informatics, Faculty of Informatics, Tokyo University of Information Sciences)
[3P-285]Inhibotion of ESCRT promote Celluer Degradation and Secretion
○Masaru Fujiwara1,2, Ryohei Sakai2, Tomohiro Kabuta2 (1. Tokyo University of Technology and Agriculture, 2. Department of Dgenerative Neurological Diseases, NCNP)
[3P-286]Cryo-EM structure of I domain-containing integrin αEβ7
○Hiroaki Akasaka1, Dan Sato, Shuhoya Wataru1, Nureki Osamu1,2, Kise Yoshiaki1,2 (1. Graduate School of Science The University of Tokyo, 2. Curreio, Inc.)
[3P-287]Disappearance of major glycolipids due to gene disruption in the extreme thermophile Thermus thermophilus HB8
○Masahiko Kawaguchi1, Haruo Shimada2, Yoshitaka Bessho3, Naoki Nemoto4,1 (1. Dept. of Eng., Grad. Sch. of Eng., Chiba Ins. of Tec., 2. BioChromato Inc., 3. RIKEN SPring-8 Center, 4. Dept. of Life Sci., Grad. Sch. of Adv. Eng., Chiba Ins. of Tec.)
[3P-288]Exploring Biomarkers in Urinary Volatile Organic Compounds (VOCs) Using SPME-Arrow/GC/MS
○Momo Sato1,2, Ryosuke Hayasaka1,2, Shinichi Akiyama3, Takahiro Imaizumi3, Takaya Ozeki3, Nobuhiro Nishibori3, Shoichi Maruyama3, Tomoyoshi Soga1,2,4, Akiyoshi Hirayama1,2,4 (1. Keio Univ., IAB, 2. Keio Univ., Grad. School of Media and Governance, 3. Nagoya Univ., Dept. of Nephrology, 4. Keio Univ., Environment and Information Studies)
[3P-289]Identification of unknown ligands of CRT on cell membranes based on glycan structures
○Koki Mayusumi1, Kazuya Kabayama1,2,3, Eiji Miyoshi4, Koichi Fukase1,2,3 (1. Dept. of Chem., Grad. Sch. of Sci., Osaka Univ., 2. FRC, Grad. Sch. of Sci., Osaka Univ., 3. Inst. for Radiation Sciences, Osaka Univ., 4. Grad. Sch. of Med., Osaka Univ.)
[3P-290]Excessive sphingolipid production in neurodegenerative diseases: Dysregulation of sphingolipid synthase activity
○Nanoka Shingai1, Ryosei Shibata2, Asami Fujikawa2, Peter Greimel 3, Hiroya Naruse4, Kayoko Esaki1,2, Tatsushi Toda4, Hiroyuki Takeya1,2 (1. Division of Applied Life Science, Graduate School of Engineering, Sojo University, 2. Department of Biotechnology and Life Sciences, Faculty of Biotechnology and Life Sciences, Sojo University, 3. Laboratory for Cell Function Dynamics, CBS, RIKEN, 4. Department of Neurology, Graduate School of Medicine, The University of Tokyo)
[3P-291]Regulatory mechanism of aromatic lactic acid production by Lactiplantibacillus spp.
○Kosuke Watanabe1, Yuh Shiwa1, Akifumi Nishida1, Nobuyuki Fujita1, Naoto Tanaka1,2 (1. Faculty of Life Sciences, Tokyo University of Agriculture, 2. NODAI Culture Collection Center, Tokyo University of Agriculture)
[3P-292]Enhanced Poly(3-hydroxybutyrate) Production from Cellobiose by Genome Engineered Priestia megaterium using CRISPR-Cas9 technology
○Tatsuya Nagano1, Vijay Kumar2, Taichi Endo Takasuka1 (1. Hokkaido Univ., 2. Guru Nanak Dev Univ.)
[3P-293]Role of CD81 in irisin-ameliorated lipid droplet metabolism via inhibition of the PPARγ/PLIN2 signaling axis in hepatocytes
○Po Han Chen1, Ying Hsien Kao2, Ming Hong Tai1 (1. Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan, 2. Department of Medical Research, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan)
[3P-294]Analysis of immune surveillance escape mechanism mediated by sialic acid-binding lectin Siglec7
○Noboru Hashimoto1,2, Sizuka Ito2, Akira Harazono3, Akiko Tsuchida2, Yasuhiro Mouri6, Tetsuya Okajima2, Akihito Yamamoto1, Nana Kawasaki5, Koichi Furukawa2,4 (1. Tissue Regene., Biomedical Sciences, Tokushima Univ., 2. Biochem. II, Nagoya Univ. Sch. Med., 3. Natl. Inst. Health Sci., 4. Biomedical Sciences, Chubu Univ., 5. Medical Life Science, Yokohama City Univ., 6. Dep. of Oral Sci., Tokushima Univ.)
[3P-295]Identification of the polyketide synthase SteelyA product and elucidation of its mode of action in Polysphondylium violaceum
○Soma Ohe1, Tamao Saito2, Takaaki Narita3 (1. Grad. Sch. of Adv. Eng , Chiba Inst. of Tech., 2. Fac. of Sci. and Tech , Sophia Univ., 3. Dept. of Life Sci. Fac . of Adv. Eng , Chiba Inst. of Tech.)
[3P-296]Enhanced the ability of nitrogen assimilation in the model cyanobacterium Synechocystis sp. PCC 6803 relieve the effects of over reducing power under high light condition.
○Kanako Iseki1, Masahiro Karikomi2, Honoka Suzuki1, Takashi Osanai2 (1. Meiji University, 2. Meiji University Graduate School)
[3P-297]Characterization of poly/oligo (ADP-ribose) presence in fetal bovine serum
○Goutham Sivanandan1, Sawa Takahashi1, Ankitha Vadi Velu1, Ying Tong1, Mitsuko Masutani1 (1. Dept. Molecular & Genomic Biomed., Sch. Med., CBMM, Nagasaki Univ. GSBS)
[3P-298]Studies on PDAT and TGL gene expression levels and TAG accumulation in Microchloropsis gaditana
○Ayumu Watanabe1, Satoru Yoshino1, Tomoe Komoriya1 (1. Nihon University)
[3P-299]Mechanism of obesity suppression through gut microbiota by rare sugars
○Kohana Ishikawa1,2, Ryoha Ichimura2,3,5, Kazuki Tanaka2,3,4,5, Shinji Fukuda2,3,4,5,6 (1. Faculty of Environment and Information Studies, Keio Univ., 2. Institute for Advanced Biosciences, Keio Univ., 3. Graduate School of Media and Governance , Keio Univ., 4. Laboratory for Regenerative Microbiology, Juntendo University Graduate School of Medicine, 5. Gut Environmental Design Group, Kanagawa Institute of Industrial Science and Technology, 6. Transborder Medical Research Center, University of Tsukuba)
[3P-300]Cultivation in the presence of H2O2 improves Exopolysaccharides (EPS) production from Lactobacillus plantarum D2905.
○Daisuke Sakamoto1, Shintarou Onomoto1, Norika Tsuyama1, Rie Mukai1, Tomomitsu Satho1, Parinya WILAI1, Keiichi Irie1, Minoru Maeda2 (1. Fukuoka Univ., 2. Kyusyu Medical Co. Ltd.)
[3P-301]Changes in the generation rate of amino acid-Amadori product with different amino acids as precursors
○Nami Ohno1, Kazumi Kita2 (1. Graduate School of Arts and Sciences, Iwate Univ., 2. Faculty of Agriculture, Iwate Univ.)
[3P-302(3PS-11-07)]The evolutionary transition of the autophagy initiation complex: changes in Atg101 dependency and Atg13-mediated Atg9 recruitment
○Zefeng Lai1, Yutaro Hama2,1, Sidi Zhang1, Masahide Oku3, Yasuyoshi Sakai4, Hayashi Yamamoto5,1, Noboru Mizushima1 (1. The University of Tokyo, 2. Hokkaido University, 3. Kyoto University of Advanced Science, 4. Kyoto University, 5. Nippon Medical School)
[3P-303]Genome-wide identification and analysis of human-specific splice sites
○Zhuo Qu1, Chie Kikutake1, Mikita Suyama1 (1. Kyushu University)
[3P-304]Whole Genome Analysis of Hydra vulgaris AEP for Elucidating Aging Mechanisms
○Kaoruko Nojiri1, Koryu Kin2, Akimasa Someya1,3, Kazuharu Arakawa4, Etsuo Susaki1,2,5 (1. Juntendo University, Faculty of Medicine, 2. Juntendo University, Graduate School of Medicine, Department of Biochemistry and Systems Medical Science, 3. Juntendo University, Faculty of Pharmacy, Department of Molecular Biology, 4. Keio University, Graduate School of Media and Governance, 5. Juntendo University, Graduate School of Medicine, Nakatani Biomedical Spatialomics Hub)
[3P-306]Evolution of slc12a10 paralogs in teleost fishes
○Chihiro Ota1, Akira Kato1 (1. School of Life Science and Technology, Institute of Science Tokyo)
[3P-307]Evolutionary Dynamics of ABC Transporters: Analysis of Intrinsically Disordered Linkers
○ICHDA DINANA DINANA1, Yukihiko Kubota1, Masahiro Ito1 (1. Ritsumeikan University)
[3P-308]Insights into Streptomyces through Amino Acid Sequence Analysis
○Shuichi Hirose1,2, Kenji Kawano2, Toshio Ariyasu1, Katsuhiro Otao1 (1. Nagase Viita Co., Ltd., 2. NAGASE & Co., Ltd.)
[3P-309]Comprehensive search for human specific de novo genes that might drive brain evolution
○RIntaro Amano Amano1, Ikuo Suzuki1, Kazuo Emoto1,2 (1. Department of Biological Science, Graduate School of Science, The University of Tokyo , 2. International Research Center for Neurointelligence (WPI-IRCN), The University of Tokyo)
[3P-310]Genetic and phenotypic structure of Japanese domestic cats based on geographical distribution
○Minori Arahori1,2 (1. Anicom Specialty Medical Institute Inc., 2. Wildlife Research Center, Kyoto University)
[3P-311]'Asymmetric Evolution' Drives the Diversification of Function in Molluscan Shells
○HIROTA KAZUKI1,2,3, DAVIN SETIAMARGA3, SHUICHI SHIGENO4, TAKENORI SASAKI2, MASA-AKI YOSHIDA5 (1. The University of Tokyo, 2. The University Museum, The University of Tokyo, 3. National Institute of Technology, Wakayama College, 4. TechnoPro R&D Company, 5. Shimane University)
[3P-312]Constructing a machine learning framework to predict the accuracy of phylogenetic tree inference
○Koki Kamada1, Motomu Matsui2 (1. Univ. of Tokyo, 2. Kyoto Univ.)
[3P-313]Evolution of Sex-Biased Genes and Sexual Dimorphism in Crickets: Insights from Chromosome-Level Genomes and Multi-Tissue Transcriptomes
○Ryuto Sanno1, Yuka Azami1, Shota Hayakawa1, Kazuya Hirata1, Kazuhiro Satomura2, Ken Naito3, Takeshi Suzuki4, Kei Yura1,5, Toru Asahi1,6, Kosuke Kataoka6,7 (1. Dept. of Adv. Sci. Eng., Grad. Sch. of Adv. Sci. Eng., Waseda Univ., 2. Dept. of Biosci., Nagahama Inst. of Bio-Sci. and Tech., 3. Res. Ctr. of Gene. Resour., Natl. Agric. and Food Res. Org., 4. Grad. Sch. Bio-App. Sys. Eng., Tokyo Univ. Agric. Tech., 5. Grad. Sch. Hum. Sci., Ochanomizu Univ., 6. Dept. of Comp. Res. Org., Waseda Univ., 7. Grad. Sch. Eng., Tokyo Univ. Agric. Tech.)
[3P-314]Functional analysis of neurological disease Temtamy syndrome-causing protein C12orf57
○Mizuho Oishi1, Kotaro Kawasaki1, Toru Asahi2,3, Wataru Onodera1 (1. Waseda Univ, School of Advanced Science and Engineering, 2. Waseda Univ, Faculty of Science and Engineering, 3. Waseda Univ, Research Organization for Nano & Life Innovation)
[3P-315]Engineering of Cross-Reactive Single-Domain Antibodies Targeting SARS-CoV2 Variants
○Hidekazu Masaki1,2, Ryo Yonehara1, Kanako Nakao1, Naoto Nemoto1,2 (1. Epsilon Molecular Engineering, 2. Saitama Univ.)
[3P-316]Meta-analysis of Public Gene Expression Data in Domesticated Animals and Their Wild Ancestors: Focusing on Pigs, Wild Boars, Chickens, and Red Junglefowl, and the Improvement of Its Methods
○Motoki Uno1, Hidemasa Bono1 (1. Grad.Sch.Integ.Sci.Life, Hiroshima Univ.)
[3P-317]Enhancing the anti-cancer activity of ADC by divalent conjugation of drugs to anti-HER2 antibody using branch linker
○Satoshi Fukuda1, Jumpei Taguchi2, Koji Umezawa3, Miho Hanya2, Tadashi Takimoto4, Toshiko Kitada1, Takashi Niwa2,4,5, Takamitsu Hosoya2,4, Isao Kii1,3 (1. Department of Agriculture, Graduate School of Science and Technology, Shinshu University, 2. Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 3. Institute for Biomedical Sciences, Shinshu University, 4. Laboratory for Chemical Biology, RIKEN BDR, 5. Graduate School of Pharmaceutical Sciences, Kyushu University)
[3P-318]Molecular Imaging of the Cardiac Conduction System
○Mirei Ishikawa1, Wakana Takeuchi1, Noriko Oshima1, Shino Homma Takeda2, Nobuko Tokuda1, Shigeru Toyoda1, Tadayuki Ogawa1 (1. Dokkyo Medical Univ., 2. QST)
[3P-319]Differentially Express Gene Analysis on Chronic Obstructive Pulmonary Disease and Evaluation of the Potential of Laminaria Japonica Compounds as Therapeutic Agents using in silico Analysis
○Irandi Putra Pratomo1,2,4, Aryo Tedjo2,3, Norma Nur Azizah2,3, Aditya Wirawan1,4, Budhi Antariksa1,5, Prasenohadi Prasenohadi1,5 (1. Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, 2. Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, 3. Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, 4. Universitas Indonesia Hospital, Universitas Indonesia, Depok, Indonesia, 5. Persahabatan Respiratory Center Hospital, Ministry of Health of the Republic of Indonesia, Jakarta, Indonesia)
[3P-320]Effect of wheat lipoxygenase expressed in baker's yeast on wheat flour dough protein components
○Shunsuke Takahashi1, Gao Yue2, Reina Miyagi2, Toshiki Saito2, Koko Nakata1, Kiwamu Shiiba1 (1. Div. Life Sci. Eng., Sch. Sci. Eng., Tokyo Denki Univ., 2. Dept. Life Sci. Eng., Grad. Sch. Sci. Eng., Tokyo Denki Univ.)
[3P-321]Development and Analysis of a Genome Editing-Related Plant Breeding Information Database for Data-Driven Genomic Breeding
○Makoto Yumiya1, Hidemasa Bono1 (1. Grad. Sch. Integ. Life, Hiroshima Univ.)
[3P-322]Minimally structured covalent reactive group with ionization enhancing ability
○Riku Katsuki1, Yamato Ikeda1, Masumi Taki1 (1. The university of electro-communications)
[3P-323]Aberrant splicing of a gene inserted into an expression vector
○Sachiko Yamamoto-Hijikata1, Kei Suga1, Makoto Ushimaru1 (1. Kyorin university)
[3P-324]Update of TogoID: ID conversion service as a basis for life science database integration
○Shuya Ikeda1, TogoID Development Team1 (1. ROIS, DS, DBCLS)
[3P-325]Development of a platform for multi-layer network analysis for diseases and biological phenomena
○Hibiki Utsuyama1, Hiroyuki Toh1 (1. KGU, Shl.Sci.Tech.)
[3P-326]Gamma irradiation analysis of Limnobacter thiooxidans, a thiosulfate-chlorinating bacterium reported to inhabit highly irradiated environments
○Tomoro Warashina1,2, Asako Sato2, Takeshi Masuda2, Yuma Dotsuta3, Toru Kitagaki3, Ayumi Hashiguchi4, Teppei Morita2, Akio Kanai1,2,5 (1. Syst. Biol. Prog. Grad. Sch. Media & Governance, Keio Univ., 2. Institute for Advanced Biosciences, Keio University., 3. Japan Atomic Energy Agency, 4. Faculty of Environmental, Life, Natural Science and Technology, Okayama University, 5. Bachelor of Arts in Environmental Information)
[3P-327]Synthesis of a novel luciferin analog aiming at high-brightness near-infrared emission
○Tatsuya Ishinuki1, Jumpei Hatakeyama1, Genta Kamiya1, Nobuo Kitada2,3, Ryohei Moriya4, Takashi Hirano1, Shojiro Maki1,2 (1. Department of Engineering Science, the university of Electro-Communications, 2. Center for Neuroscience and Biomedical Engineering, 3. Coordinated Center for UEC Research Facility, 4. Faculty of Science, Japan Women's University)
[3P-328]An on-line detection system for screening inhibitors of α-amylase in Polygala tenuifolia and molecular docking
○Yuangui Yang1, Zenghu Su1, Hongbo Xu1, Shizhong Chen2 (1. Shaanxi University of Chinese Medicine, 2. Peking University)
[3P-329]Analysis of Ionizable Lipids and Their Metabolites in Mouse Liver Using LC/MS: Supporting LNP Development
○Qiuyi Wang1,2, Tsuyoshi Nakanishi1, Sachiko Sakamoto3, Keiko Kajiwara3, Kaoru Nakagawa1, Arisa Ito2, Ayako Matsunawa3, Hiroyuki Tanaka3, Masayuki Sugimoto3, Hirofumi Ebe3, Kenjiro Minomi3, Natsuyo Asano1, Naoki Morita1, Tadayuki Yamaguchi1, Junko Iida1,2 (1. Shimadzu Corporation, 2. Shimadzu Analytical Innovation Research Laboratories, Osaka University, 3. Nitto Denko Corporation)
[3P-330]Candidate therapeutic compounds selection rule for the xeroderma pigmentosum complementation group D mutant (R683W) as determined by in silico drug repurposing screening
○Aki Sugano1,2,4, Mika Ohta2,3, Satoshi Tateishi5, Yoshimasa Maniwa2, Yutaka Takaoka2,3,4 (1. CCTR, Toyama Univ. Hosp., 2. Dept. of Med. Syst., Kobe Univ. Grad. Sch. of Med., 3. Dept. of Comput. Drug Design and Math. Med., Grad. Sch. of Med. and Pharma. Sci., Toyama Univ., 4. Center for DS and AI Res. Promot., Toyama Univ. Hosp., 5. Dept. of Cell Maintenance, IMEG Kumamoto Univ.)
[3P-331]Analysis of interaction between fatty acid membrane and nucleic acid monomers using molecular dynamics simulations
○Ryoji Abe1, Taren Ginter1, Kosuke Fujishima1,2 (1. Institute of Science Tokyo, 2. Earth Life Sciene Institute)
[3P-332]The Genome-wide association of DNA methylation QTLs in whole blood highlights causal mechanism for metabolic syndrome
○Ho-Sun Lee1,2 (1. National Forensic Service, 2. Seoul National University)
[3P-333]Development of a Biorepository Technical Administrator Certification Program for Specialists Handling Biological Samples/Associated Data
○Junko Ikeda1, Kazuhiro Okano2, Shin-ichiro Fujii3, Yoshihito Nakajima4, Keiko Misawa1, Hiroki Nakae1, Hiroyuki Kobayashi5, Ayuko Nemoto6, Kotaro Hattori7, Tomoyo Takeuchi8, Yohei Miyagi9, Kazuyuki Matsushita10, Mizuki Morita11, Soichi Ogishima12,13, Naoko Minegishi13, Takayuki Morisaki14 (1. Council for Industrial use of Biological and Environmental Repositories, 2. Agilent Technologies, Inc., 3. National Metrology Institute of Japan, National Institute of Advanced Industrial Science and Technology, 4. Thermo Fisher Scientific K.K., 5. SHIONOGI & CO., LTD., 6. Aquaxis Law Office, 7. Medical Genome Center, National Center of Neurology and Psychiatry, 8. Tsukuba Human Tissue Biobank, University of Tsukuba Hospital, 9. Kanagawa Cancer Center Research Institute, 10. Chiba University, 11. Graduate School of Interdisciplinary Science and Engineering in Health Science, Okayama University, 12. Tohoku University Advanced Research Center for Innovations in Next-Generation Medicine, 13. Tohoku Medical Megabank Organization, Tohoku University , 14. BioBank Japan, The Institute of Medical Science, The University of Tokyo)
[3P-334]Potency of agarose-gel supported lipid bilayers for electrophysiological analysis of channel-pores formed by Bacillus thuringiensis insecticidal proteins.
○Tsubasa Okuda1, Tomoya Takeuchi1, Mami Asakura1, Minako Hirano1, Toru Ide1, Tohru Hayakawa1 (1. Okayama Univ.)
[3P-335]Mutational analysis of the mosquitocidal Mpp46Ab transmembrane β-hairpin region
○Kiyotaka Shimokawara1, Ryoya Kodani1, Minako Hirano1, Toru Ide1, Tohru Hayakawa1 (1. Okayama University)
[3P-336]Application of chromosome engineering technology (1):Development of chromosome transfer technology using density gradient centrifugation
○Hiroaki Kobayashi1, Hitomi Sakano2, Hitomaru Miyamoto1, Kyotaro Yamazaki3, Kanako Kazuki4, Masaharu Hiratsuka2,4, Teruhiko Suzuki5, Yasuhiro Kazuki1,2,3,4 (1. Div. of Chr. Biomed. Eng., Grad. Sch. of Med. Sci., Tottori Univ., 2. Sch. of Life Sci., Facul. of Med., Tottori Univ., 3. Chr. Eng. Group, ExCELLS, 4. CERC, Tottori Univ., 5. Stem Cell Proj., Tokyo Metropol. Inst. Med. Sci.)
[3P-337]Application of chromosome engineering technology (2): Construction of mouse ES cell clones containing a single human chromosome by using human iPS cells as a chromosome donor
○koki kuroiwa1, Hitomaru Miyamoto1, Kyotaro Yamazaki2, Chihiro Yoshimatsu1, Narumi Uno3, Teruhiko Suzuki4, Kanako Kazuki5, Kazuma Tomizuka3, Yasuhiro Kazuki1,2,5 (1. Div. of Chromosome Biomedical Engineering., Grad. Sch. of Med. Sci., Tottori Univ., 2. Chr. Eng. Group, ExCELLS, 3. Lab. of Bioeng., Sch. of Life Sci., Tokyo Univ. of Pharm. and Life Sci., 4. Stem Cell Proj., Tokyo Metropol. Inst. Med. Sci., 5. CERC, Tottori Univ.)
[3P-338]Application of chromosome engineering technology (3): Generation and analysis of chromosome 21, X,Y aneuploidy cells using the chromosome transfer method from human iPS cells to human iPS cells
○Narumi Uno1, Hitomaru Miyamoto2, Kyotaro Yamazaki3, Masaya Egawa1, Hiroaki Kobayashi2, Teruhiko Suzuki4, Shusei Hamamichi5, Kanako Kazuki5, Mitsuo Oshimura2, Kazuma Tomizuka1, Yasuhiro Kazuki2,3,5 (1. Lab. of Bioeng., Sch. of Life Sci., Tokyo Univ. of Pharm and Life Sci., 2. Div. of Chromo. Biomed. Eng., Grad. Sch. of Med. Sci., Tottori Univ., 3. Chr. Eng. Group, ExCELLS, 4. Stem Cell Proj., Tokyo Metropol. Inst. Med. Sci., 5. CERC, Tottori Univ.)
[3P-339]Application of chromosome engineering technology (4): Establishment of chromosome modification methods using CRISPR/Cas9 technology for construction and analysis of partial monosomy of the long arm of chromosome 21
○Masaya Egawa1, Narumi Uno1, Hitomaru Miyamoto2, Yuki Ishizu1, Rina Komazaki1, Yusuke Ohkame3, Chihiro Yoshimatsu2, Kyotaro Yamazaki4, Yasuhiro Kazuki2,3,4, Kazuma Tomizuka1 (1. Lab. of Bioeng., Sch. of Life Sci., Tokyo Univ. of Pharm and Life Sci, 2. Div. of Chromo. Biomed Eng., Grad. Sch. of Med. Sci., Tottori Univ., 3. CERC, Tottori Univ., 4. Chr. Eng. Group, ExCELLS)
[3P-340]Application of chromosome engineering technology (5): Genome minimization using human iPS cells with partial monosomy of chromosome 21 generated by megabase chromosome deletions
○Yusaku Okano1, Ayami Seno1, Rina Komazaki1, Yuki Ishizu1, Masaya Egawa1, Yusuke Ohkame2, Chihiro Yoshimatsu3, Kyotaro Yamazaki4, Teruhiko Suzuki5, Yasunori Aizawa6, Narumi Uno1, Yasuhiro Kazuki2,3,4, Kazuma Tomizuka1 (1. Lab. of Bioeng., Sch. of Life Sci., Tokyo Univ. of Pharm and Life Sci., 2. CERC, Tottori Univ., 3. Div. of Chromo. Biomed Eng., Grad. Sch. of Med. Sci., Tottori Univ., 4. Chr. Eng. Group, ExCELLS., 5. Stem Cell Proj., Tokyo Metropol. Inst. Med. Sci., 6. Sch. Life Sci. Tech., Tokyo Tech.)
[3P-341]Application of chromosome engineering technology (6): Chromosomal reciprocal translocation in human iPS cells towards the regulation of chimeric T-cell receptor gene expression using human artificial chromosomes
○Shino Okado1, Jyukiya Kitazawa1, Narumi Uno1, Masaya Egawa1, Akihiro Ishikawa2, Masaharu Hiratuka3, Yusuke Ohkame3, Shinn Kaneko2, Yasuhiro Kazuki3,4,5, Kazuma Tomizuka1 (1. Lab. of Bioeng., Sch. of Life Sci., Tokyo Univ. of Pharm. and Life Sci.,, 2. CiRA, Kyoto Univ., 3. CERC, Tottori Univ.,, 4. Div. of Chr. Biomed Eng., Grad. Sch. of Med. Sci., Tottori Univ.,, 5. Chr. Eng. Group, ExCELLS)
[3P-342]Application of chromosome engineering technology (7): Loading human chromosome regions onto human artificial chromosomes by inducing chromosomal reciprocal translocations using genome editing in human iPS cells
○Jukiya Kitazawa1, Shino Okado1, Narumi Uno1, Masaya Egawa1, Akihiro Ishikawa2, Masaharu Hiratuka3, Yusuke Ogame3, Shin Kaneko2, Yasuhiro Kazuki3,4,5, Kazuma Tomizuka1 (1. Lab. of Bioeng., Sch. of Life Sci., Tokyo Univ. of Pharm. and Life Sci., 2. CiRA, Kyoto Univ., 3. CERC, Tottori Univ., 4. Div. of Chr. Biomed Eng., Grad. Sch. of Med. Sci., Tottori Univ., 5. Chr. Eng. Group, ExCELLS)
[3P-343]Application of chromosome engineering technology (8): Identification of a novel housekeeping gene promoter activity enhancing sequence
○Rio Suzuki1, Natsumi Miyazaki1, Chihiro Onodera1, Narumi Uno1, Yasuhiro Kazuki2,3, Kazuma Tomizuka1 (1. Lab. of Bioeng., Sch. of Life Sci., Tokyo Univ. of Pharm and Life Sci., 2. CERC, Tottori Univ., 3. Div. of Chromo. Biomed. Eng., Grad. Sch. of Med. Sci., Tottori Univ.)
[3P-344]Application of chromosome engineering technology (9): Development of designer mesenchymal stem cells for the treatment of spinal cord injury using human artificial chromosomes and sendai virus vectors
○Kai Takashima1,2, Genki Hichiwa1,2, Yayan Wang1,2, Kanako Kazuki2, Satoshi Abe2, Mitsuo Oshimura3, Yasuhiro Kazuki1,2,4 (1. Div. of Chromosome Biomedical Engineering., Grad. Sch. of Med. Sci., Tottori Univ, 2. CERC, Tottori Univ, 3. Trans Chromosomics, Inc, 4. Chr. Eng. Group, ExCELLS:ExCELLS)
[3P-345]Application of chromosome engineering technology (10): Construction of synthetic human centromeres reveals the structure and epigenetic regulation of CENP-A dense and sparse regions
○Junichiro Ohzeki1, Kyotaro Yamazaki1, Kazuto Kugou2, Koei Okazaki2, Megumi Nakano2, Koichiro Otake2, Kenta Shirasawa2, Sachiko Isobe2, Yusuke Endo2, Hiroshi Masumoto2, Yasuhiro Kazuki1,3,4,5 (1. Chr. Eng. Group, ExCELLS, 2. Kazusa DNA Res. Inst., 3. Div. of Chr. Biomed. Eng., Grad. Sch. of Med. Sci., Tottori Univ., 4. CERC, Tottori Univ., 5. Sch. of Life Sci., Facul. of Med., Tottori Univ.)
[3P-346]Application of chromosome engineering technology (11): Development and analysis of human IgH/Igλ antibody-producing mice by using artificial chromosome
○Kazuto Shimoya1, Takashi Moriwaki2,3, Yuana Masuda2, Shigenori Baba2, Akane Okada3, Kanako Kazuki3, Satoshi Abe3, Yasuhiro Kazuki1,2,3,4 (1. Department of Chromosome Biomedical Engineering, Graduate School of Medical Sciences, Tottori Univ., 2. Department of Chromosome Biomedical Engineering, School of Life Science, Faculty of Medicine, Tottori Univ., 3. Chromosome Engineering Research Center (CERC), Tottori Univ., 4. Chromosome Engineering Research Group, Exploratory Research Center on Life and Living Systems (ExCELLS))
[3P-347]Nuclear F-actin formation regulates decidualization of human endometrial stromal cells
○Isao Tamura1, Kei Miyamoto2, Toshihide Yoneda1, Nitomi Takasaki1, Taishi Fujimura1, Norihiro Sugino1 (1. Yamacuhi Univ., 2. Kyushu Univ)
[3P-348]Exploring Kinetochore Components Lacking CENP-A and CENP-C in the Mucorales Fungus, Mucor lusitanicus
○Haruhiko Asakawa1, Shreyas Sridhar1, Tatsuo Fukagawa1 (1. Osaka University)
[3P-349]Arrayed CRISPRi library for essential genes in a fission yeast
○Ken Ishikawa1, Saeko Soejima1, Takashi Nishimura2, Saitoh Shigeaki1 (1. Kurume Univ., 2. Gunma Univ.)
[3P-350]Leaf-formation factor ASYMMETRIC-LEAVES2 of Arabidopsis is involved in nuclear localization of 45S-rDNA repeats and attenuates nucleolar stress
Sayuri Ando1, Rina Kawamoto1, Hidekazu Iwakawa2, Iwai Ohbayashi3, Yasuhiro Kamei4, Masaki Ito2, Munetaka Sugiyama5, Michiko Sasabe6, Yasunori Machida7, Shoko Kojima1, ○Chiyoko Machida1 (1. Chubu Univ., 2. Kanazawa Univ., 3. National Cheng Kung Univ. , 4. NIBB, 5. Univ. of Tokyo, 6. Hirosaki Univ., 7. Nagoya Univ.)
[3P-351]Contribution of mtDNA to chromosomal segregation pattern in interspecific hybrids
○Ken-Ichi Wada1,2,3,4, Kazuo Hosokawa4, Mizuo Maeda4, Yoshihiro Ito4, yui Harada2, Yoshikazu Yonemitsu2 (1. IMCE, Kyushu Univ., 2. Fac. Pharm. Sci., Kyushu Univ., 3. Fac. Eng., Kyushu Univ., 4. RIKEN)
[3P-352]Determination of the order of chicken W chromosome contigs using the chromosomal truncation method
○Miku Sojo1, Takehiro K Katoh2, Rika Rifana Sari1, Kouji Hirota1, Masafumi Nozawa2,3, Takuya Abe4 (1. Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University, 2. Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, 3. Research Center for Genomics and Bioinformatics, Tokyo Metropolitan University, 4. Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University)
[3P-353]Analysis of RNAs to form an RNA cloud using RADICL-seq technology
○Masaki Kato1, Yuichi Ichikawa2, Xufeng Shu1, Maierdan Palihati2, Noriko Saitoh2, Piero Carninci1,3 (1. RIKEN IMS, 2. The Cancer Institute of JFCR, 3. Human Technopole)
[3P-354]Regulation of p53-dependent nuclear actin dynamics mediated by caspases
○Mako Sumida1, Takeru Torii1, Wataru Sugimoto1, Katsuhiko Itoh1, Shinya Taniguchi1, Shin Kuwamoto1, Yuta Shimamoto2, Hiroaki Hirata3, Keiko Kawauchi1 (1. Faculty of frontiers of Innovative Research in Science and Technology (FIRST), Konan University, 2. National Institute of Genetics, 3. Kanazawa Institute of Technology)
[3P-355]Mechanism and significance of nuclear invagination in epithelial cells
○Le Minh Khoa1, Hiroshi Kimura1,2 (1. Institute of Science Tokyo, School of Life Science and Technology, 2. Institute of Science Tokyo, Institute of Integrated Research)
[3P-356]Search for factors that regulate fluctuations in X chromosome inactivation and reactivation
○Rena Hasegawa1, Hiroshi Kimura1,2 (1. Institute of Science Tokyo, School of Life Science and Technology, 2. Institute of Science Tokyo, Institute of Integrated Research, Cell Biology Center)
[3P-357]Characterization and function of host RNAs recruited to mumps virus inclusion bodies
○Hiroshi Katoh1, Ryuichi Kimura2, Tsuyoshi Sekizuka3, Kohei Matsuoka1, Mika Hosogi1, Fumihiro Kato3, Yuki Kitai1, Yukiko Akahori1, Yasuyuki Ohkawa4, Shinya Oki2, Makoto Takeda1 (1. The University of Tokyo, 2. Kumamoto University, 3. National Institute of Infectious Diseases, 4. Kyushu University)
[3P-358]Cell-free reconstitution of nuclear stress bodies using artificial repeat RNAs and elucidation of their formation mechanisms
○Yuichi Matsuda1, Shungo Adachi2, Manami Kakuno1, Ryujirou Nakamura3, Junichi Iwakiri4, Kiyoshi Asai4, Tomohiro Yamazaki3, Kensuke Ninomiya3, Tetsuro Hirose1,3,5 (1. Graduate School of Science, Osaka University, 2. National Cancer Center Research Institute, 3. Graduate school of Frontier Biosciences, Osaka University, 4. Graduate School of Frontier Sciences, The University of Tokyo, 5. OTRI, Osaka University)
[3P-359]hnRNPs bi-directionally regulate stress granule growth and disassembly
○Kyota Yasuda1,3,4, Miyu Murata1, Rina Mihara1, Hyun-woo Rhee2,3, Shin-ichi Tate1,3,4 (1. Hiroshima University, 2. Seoul national university, 3. WPI-SKCM2, 4. RcMcD)
[3P-360]Classification of low-complexity regions of LLPS-related proteins
○Yuhei Ozawa1, Satoshi Fukuchi2 (1. Dept. of Life Sci. & Info., Grad. Sch. of Tec., Maebashi Ins. of Tec., 2. Maebashi Institute of Technology)
[3P-361(3PS-03-05)]iChIP, a screen method to isolate protein complexes on a specific promoter in planta, identified novel transcriptional regulators of hormone biosynthesis under environmental stress conditions
○Hikaru Sato1,2, Satoru Fujimoto3, Miki Fujita2, Fuminori Takahashi2, Keiko Kuwata4, Sachihiro Matsunaga1,3, Kazuko Yamaguchi-Shinozaki5,6, Kazuo Shinozaki2 (1. Dept. of Integr. Biosci., Univ. Tokyo, 2. RIKEN CSRS, 3. Dept. of Appl. Biol. Sci., Tokyo Univ. of Sci., 4. ITbM, Nagoya Univ., 5. Grad. Sch. Agr. Life Sci., Univ. Tokyo, 6. Res. Inst. Agr. Life Sci., Tokyo Univ. Agr.)
[3P-362]Effects of liquid-liquid phase separation of NPM1 on the nucleolar structure.
○Taiyo Kikuchi1, Shoko Saito1, Mitsuru Okuwaki1 (1. Schl. Pharm., Kitasato Univ.)
[3P-363]Comparative analysis of Vasa orthologue GLH in nematodes: Insights into the universality and diversity of germ granule formation mechanisms
○Taichi Kusano1, Minami Noro1, Bang Uikyu1, Satoshi Namai1, Nami Haruta1, Asako Sugimoto1 (1. Tohoku University)
[3P-364(3AS-17-06)]Analysis of Msp1-mediated re-targeting mechanism of mislocalized peroxisomal membrane proteins
○Yoshiki Kogure1, Tomoyuki Numata1, Toshiya Endo2, Shunsuke Matsumoto1 (1. Dept. of Biosci. and Biotech., Grad. Sch. Bioresource & Bioenviron. Sci., Kyushu Univ., 2. Faculty of Life Sciences, Kyoto Sangyo Univ.)
[3P-365(3AS-05-06)]Tissue-to-tissue communication via plants EV ~ for elucidation of drought stress responses~
○Haruka Otani1, Wakana Inoue1, Suzuki Takehiro2, Naoshi Dohmae2, Fuminori Takahashi3 (1. Grad. Sch., TUS, 2. RIKEN, 3. TUS)
[3P-366]Cryo-EM structures of a mitochondrial AAA-ATPase Msp1 and ATAD1 provide insight into the ATP-dependent substrate extraction
○Daiki Inamoto1, Tomoyuki Numata1, Toshiya Endo2, Shunsuke Matsumoto1 (1. Dept. Biosci. and Biotech., Grad. Sch. Bioresource & Bioenviron. Sci., Kyushu Univ., 2. Faculty of Life Sciences, Kyoto Sangyo Univ.)
[3P-367]Deubiquitinating enzyme USP5 promotes stress granule disassembly by modulating the recruitment of disassembly factors
○SUWIJAK MOOLCHUA1, MASAYUKI KOMADA2, TOSHIAKI FUKUSHIMA2 (1. School of Life Science and Technology, Institute of Science Tokyo, 2. Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo)
[3P-368]Functional analysis of Msp1 under mitochondrial import stress conditions induced by clogger
○Yuhi Tsukahara1, Tomoyuki Numata2, Toshiya Endo3, Shunsuke Matsumoto2 (1. School of Agriculture, Kyushu Univ., 2. Dept. Biosci. & Biotech., Grad. Sch. Bioresource & Bioenviron. Sci., Kyushu Univ., 3. Faculty of Life Sci., Kyoto Sangyo Univ.)
[3P-369]Role of MPIase in the membrane protein biogenesis
○Nachi Yamamoto1, Fuka Fujimura1, Hanako Nishikawa1, Pattama Wiriyasermkul1,2,3, Shushi Nagamori2,3, Ken-ichi Nishiyama1 (1. Dept. of Biol. Chem., Fac. of Agriculture., Iwate Univ., 2. Center for SI Med. Res., The Jikei Univ. School of Med., 3. Dept. of Lab. Med., The Jikei Univ. School of Med.)
[3P-370]Elucidation of the localization control mechanism of transcription factor Nrf1
○Goki Yamada1,2, Tomoaki Hirakawa1,2, Marino Kita3, Tadayuki Tsujita1,2,3 (1. The United Graduate School of Agricultural Sciences, Kagoshima University, 2. Faculty of Agriculture, Saga University, 3. Faculty of Advanced Health Science, Saga University)
[3P-371(3AS-17-02)]Compensatory degradation mechanism of misfolded CFTR in the ER quality control system
○Tsukasa Okiyoneda1, Uta Nakayamada1, Aika Fujii1, Saori Katoh1, Yuka Kamada1 (1. Kwansei Gakuin University)
[3P-372]Differential subcellular localization of the transcription factor Prox1 in the developing hippocampus and its regulatory mechanisms
○Taichi Kashiwagi1, Sae Kaneko1,2 (1. Tokyo Med. Univ., 2. Tokyo Univ. Pharm. Life Sci.)
[3P-373]A molecular mechanism of localization of KPNA1/Importin α5 into nucleoli in neuron.
○Osamu Kutomi1,2, Katsutoshi Mizuno1,2, Takafumi Itoh3, Masami Yamada1,2 (1. University of Fukui, 2. Life Science Innovation Center, University of Fukui, 3. Fukui Prefectural University)
[3P-374]Effects of Intracellular Localization of the Aging and Obesity-Related Factor PARIS on Its Accumulation
○Hiroto Fukai1, Yuhei Mizunoe1, Yuka Nozaki1, Masaki Kobayashi2, Yoshikazu Higami1,3 (1. Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2. Faculty of Care Research Natural Sciences Division, Ochanomizu University, 3. Research Institute for Biomedical Sciences, Tokyo University of Science)
[3P-375]Molecular and Structural Bases of Nuclear transportation of ZFTA-RELA fusion protein that drives ependymoma
○Shinya Ohata1, Sachiko Toma2,3, Yuki Matsuya3, Koki Hayama2, Hikaru Shimizu3, Hiroaki Matsuura4, Naoki Sakai4, Kunio Hirata4, Hironari Kamikubo2, Masaki Ishii1, Toshiaki Katada1, Toshiyuki Shimizu3 (1. Musashino University, 2. NAIST, 3. Univ. of Tokyo, 4. RIKEN)
[3P-376]Cellular mechanisms controlling localization of ABCC2 to the apical plasma membrane in polarized epithelial cells.
○Yoshikazu Emi1, Masao Sakaguchi1 (1. University of Hyogo)
[3P-377]Elucidation of the mechanism of Tau aggregation using the light-dependent aggregation system "OptoTau"
○Toshiki Takahashi1, Shigeo Sakuragi1, Yoshiyuki Soeda2, Hideaki Yoshimura3, Akihiko Takashima2, Hiroko Bannai1 (1. Waseda univ., 2. Gakushuin univ., 3. Tokyo univ.)
[3P-378(3PS-11-09)]Identification and analysis of Rab22A-GAPs involved in tubular endosome formation
○Shumpei Nakashima1, Mitsunori Fukuda1 (1. Lab. of Membr. Trafficking Mech., Grad. Sch. of Life Sci., Tohoku Univ.)
[3P-379(3PS-13-08)]The mechanism of mitochondrial dynamics via PIPs metabolism
○Sho Aki1, Tsuyoshi Osawa1 (1. The University of Tokyo)
[3P-380(3PS-12-03)]Lipidomic changes impact the morphology of the mitochondria
○Gaoge Wang1,2, Ulrike Eggert1 (1. King's College London, 2. Beijing Life Science Academy)
[3P-381(3PS-11-04)]Characterization of pre-peroxisomal vesicles released from mitochondria
○Ayumu Sugiura1, Yoshiki Miura1, Hikari Taka1, Heidi May McBride2, Yasushi Okazaki1,3 (1. Juntendo University, 2. McGill University, 3. RIKEN)
[3P-382(3PS-13-06)]The mitochondrial protein C15ORF48 is an inducer of autophagy in thymic epithelial cells that regulates immunotolerance.
○Noritaka Yamaguchi1,2, Yuki Takakura1,2, Nobuko Akiyama2, Hiroyuki Takano1, Taishin Akiyama2 (1. Chiba University, 2. RIKEN)
[3P-383]Observation of Golgi satellites, Golgi-related organelles specific for neurons.
○Kana Hasegawa1, Kensuke Hayashi1 (1. Sophia University)
[3P-384]Exploration on regulators controlling autophagy termination
○BOHAN CHEN1, Takeshi Noda1,2,3 (1. Graduate School of Frontier Biosciences, Osaka University, 2. Graduate School of Dentistry, Osaka University, 3. Center for Infectious Disease Education and Research, Osaka University)
[3P-385(3PS-13-07)]Ca2+-mediated ER-mitochondria crosstalk during plasma membrane damage-dependent senescence
○Kojiro Suda1, Yohsuke Moriyama1, Keiko Kono1 (1. OIST)
[3P-386]Structural insights into the endosome-ER membrane contact sites in MLN64-overexpressing cells.
○Natsuki Sawa1, Megumi Murakami2, Akio Huzihasi2, Atsuki Nara1,2 (1. Nagahama Biotechnology Graduate School・Graduate School of Biological Sciences・Organelle Structure Functions, 2. Nagahama Institute of Bio-Science and Technology・Faculty of Biological Sciences・Department of Medical Biological Sciences・Organelle Structure Functions)
[3P-387]A nutrient sensing mechanism through organelle dynamics in cancer cells
○Tomoya Matsushita1, Sumire Nakagawa, Mayu Asao2, Sho Aki1,2,3, Tuyoshi Osawa1,2,3 (1. Department of Chemistry & Biotechnology School of Engineering, The University of Tokyo, 2. Department of Department of Advanced Interdisciplinary Studies, The University of Tokyo, 3. RCAST The University of Tokyo)
[3P-388]Mechanism of endoplasmic reticulum mannosidase EDEM2ｰS- SｰTXNDC11 complex formation.
○Shuichiro Oshita1, Moe Yamashiro1, Noritaka Hashii2, Yen Liew Chia3, Ting Lin Yen3, Kung Ni Chi 3, Hirokazu Yagi4, Satoshi Ninagawa1,5 (1. Graduate School of Kobe University, 2. National Institute of Health Sciences, 3. Institute of Atomic and Molecular Sciences, Academia Sinica, 4. Graduate School of Pharmaceutical Sciences, Nagoya City University, 5. Biosignal Research center KOBE University)
[3P-389]Development of cargo delivery system using liposomes with extracellular vesicle membrane
○Kenta Arai1, Chie Mori1, Noriko Fukuta1, Shouhei Kobayashi1 (1. Bio-ICT Laboratory, Kobe Frontier Research Center, Advanced ICT Research Institute, National Institute of Information and Communications Technology (NICT))
[3P-390]Monitoring of GTP consumption at the mitochondrial membrane surface by fluorescence lifetime imaging
○Koki Miyata1, Loan Thi Ngoc Nguyen2, Nanako Kobayashi1, Haruto Kobayashi1, Yuta Imai1, Cong Quang Vu2, Satoshi Arai2, Yuhei Araiso1 (1. Div. of Health Sci., Kanazawa Univ., 2. NanoLSI, Kanazawa Univ.)
[3P-391]Isorhamnetin activates autophagy through the transcription factor GATA
○Yuki Marugame1, Saki Shiota1, Satoshi Yano1, Taichi Hara1 (1. Waseda university)
[3P-392]Effect of cytosol-localized catalase on BDNF expression in astrocyte-like cells
○e.g. Koya e.g. Miyamura1, e.g. Yuichi e.g. Abe1 (1. Sojo University)
[3P-393]Functional analyses of a novel vesicular membrane protein, TMEM141 during the growth stage in medaka (Oryzias latipes) larvae
○Yasuhiro Tonoyama1, Tamami Adachi2, Nahoko Bailey Kobayashi2,3, Tetsuhiko Yoshida2,3, Jun Kudoh2, Mikio Kato4 (1. Shonan University of Medical Sciences , 2. Keio University, 3. Toagosei, Co .,Ltd, 4. Osaka Metropolitan University)
[3P-394]Functional analysis of hVMS1 to prevent mitochondrial oxidative stress followed by proteasome inhibition
Yuki Iwata1, Sunita Maharjan2, Yasuyoshi Sakai2, ○Jun Hoseki1 (1. KUAS, 2. Kyoto Univ.)
[3P-395]Elucidation of the quantitative regulation mechanism between organelles using multiplex IF method
○Yoshihiko Inoue1, Narikawa Naeko2, Rina Kunishige3, Fumi Kano3 (1. Science Tokyo, 2. Institute of Science Tokyo, Institute of Integrated Research, Cell Biology Center, 3. Institute of Science Tokyo, Institute of Integrated Research, Multimodal Cell Analysis Collaborative Research Cluster)
[3P-396]The mechanism of damaged lysosome clearance by cytosol-localized E3 ligase RNF115
○Sae Nakanaga1, Hiroyuki Kawahara1 (1. Tokyo Metropolitan University)
[3P-397]Extracellular matrix enables myoblasts to engraft into intact skeletal muscle tissue
○Kitora Dohi1, Yasuko Manabe1, Nobuharu Fujii1, Yasuro Furuichi1 (1. Tokyo Metroporitan Univercity)
[3P-398]Towards Elucidating the Cellular and Molecular Mechanisms of Siliceous Spicule Transport by Collective Cell Behavior in the Freshwater Sponge, Ephydatia fluviatilis
○Tomoyuki Ueda1, Makoto Kashima2, Noriko Funayama1 (1. Dept. of Biophysics, Grad. Sch. of Science, Kyoto Univ., 2. Dept. of Biomolecular Science, Faculty of Science, Toho Univ.)
[3P-399]Developing technologies for spatial control of extracellular matrix in vitro for mimicking the natural human ECM
○Yen Xuan Ngo1,2, Kasinan Suthiwanich2,3, Masaya Hagiwara1,2 (1. Center for Biosystems Dynamics Research RIKEN, 2. Clustering of Pioneering Research RIKEN, 3. Toronto General Hospital Research Institute University Health Network)
[3P-400]Phosphorylation activity of LRRK2 is involved in fMLP-stimulated neutrophil chemotaxis
○Yuichi Mazaki1, Haruka Handa2, Yoshizuki Fumoto3, Takahiro Horinouchi1, Yasuhito Onodera4 (1. Dept. Cell. Pharm., Grad. Sch. Med., Hokkaido Univ., 2. Div. Mol. Psychoneuroimmuno., Inst. Genetic. Med, Hokkaido Univ., 3. Dept. Mol. Biol., Grad. Sch. Med., Hokkaido Univ., 4. Glb. Ctr. Biomed. Sci. Eng., Fac. Med., Hokkaido Univ.)
[3P-401]Effect of photoactivated adenylyl cyclase expression on Salmonella flagellar motility
○Keisuke Sakai1, Yusuke V. Morimoto1 (1. Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology)
[3P-402]Bilateral global cellular flow displays asymmetry prior to left-right organizer formation
○Rieko Asai1,2, Shubham Sinha3, Vivek N Prakash3, Takashi Mikawa2 (1. Kumamoto Univ. IRCMS, 2. UCSF, CVRI, 3. Univ. of Miami)
[3P-403]Enhancement of stress-activated protein kinase (SAPK) phosphorylation in A549 lung carcinoma cells by culture on type I collagen gels
○Hitomi Fujisaki1, Sugiko Futaki2, Kiyotoshi Sekiguchi3, Toshihiko Hayashi4, Shunji Hattori1 (1. Nippi Research Institute of Biomatrix, 2. Anatomy and Cell Biology, Faculty of Medicine, Osaka Medical and Pharmaceutical University, 3. Division of Matrixome Research and Application, Institute for Protein Research, Osaka University, 4. Wuya college of Innovation, Shenyang Pharmaceutical University)
[3P-404]Generation of monoclonal antibodies specifically recognizing
thrombin-cleaved nephronectin
○Machiko Honda1, Tatsuya Segawa2, Katsuyoshi Hamada2, Shigeyuki Kon1 (1. Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University Laboratory of Molecular immunology, 2. Immuno-Biological Laboratories Co., Ltd.)
[3P-405]Intracellular Calcium Responses to External Calcium Stimuli Using a Calcium Biosensor GCaMP3 in Dictyostelium
Dahyeon Kim1, ○Taeck Joong Jeon1 (1. Chosun Univeristy)
[3P-406]Analysis of the contribution of airway ciliary motility to SARS-CoV-2 using a mouse model of ciliopathy
○Kao Nakajima1, Yohei Takeda2, Haruko Ogawa2, Kyosuke Shinohara1 (1. Tokyo University of Agriculture and Technology, 2. Obihiro University of Agriculture and Veterinary Medicine)
[3P-407]The intracellular localization of Annexin A2 is regulated by cell-cell adhesion and actomyosin activity
○Souta Takeuchi1, Kazuki Shima2, Hiroaki Hirata2 (1. Dept. Biol., Grad Sch. of Eng., Kanazawa Inst. Tech., 2. Dept. Appl. Biol., Kanazawa Inst. Tech.)
[3P-408]Development of a Novel Bioink for 3D Bioprinting Using Cell Cross-linked Hydrogels
○Akihiro Mikuma1, Natsumi Ueda1, Yuri Yasunisi1, Koji Nagahama1 (1. Konan University)
[3P-409]Molecular basis of regulation of lepidopteran wing scale nanostructure formation
Yuto Kitamura1, Kenta Ohdaira2, Yoko Takasu3, Keiro Uchino3, Tetsuya Iizuka3, Hideki Sezutsu3, Ryo Futahashi4, ○Mizuko Osanai-Futahashi1,2 (1. Graduate School of Science and Engineering, Ibaraki University , 2. Department of Science, Ibaraki University, 3. Institute of Agrobiological Science, National Agriculture and Food Research Organization (NARO), 4. Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST))
[3P-410]Shaker-like Potassium Channel Is Involved in Regulating the Migration Speed in Dictyostelium
○hyunjoong Kim1,2, Taeck Joong Jeon1,2 (1. Department of Integrative Biological Sciences & BK21 FOUR Educational Research Group for Age-associated Disorder Control Technology, Chosun University, Gwangju 61452, Republic of Korea, 2. Research Institute of Chosun Natural Science & CSU G-LAMP Project Group, Chosun University, Gwangju, 61452, Republic of Korea)
[3P-411]Cytoplasmic delivery of ZO-1 during Tight junction formation in the keratinocytes
○Reika Saito1, Yohei Hirai1 (1. Department of Biomedical Science, School of Biological and Environmental Science, Kwnsei Gakuin University)
[3P-412]Analysis of ATPase involved in pilus elongation and retraction from Thermus thermophilus
○Hirono Usami1, Masumi Maekawa1, Megumi Migita1, Hiromi Yoda2, Ayumi Koike-Takeshita1,2 (1. Dept. Appl. Chemi. Biosci., Grad. Sch. Eng., Kanagawa Inst. of Tech., 2. Biomed. Res. Ctr., Kanagawa Inst. of Tech.)
[3P-413]Extracellular vesicles formation by I-BAR Protein ABBA in glioblastoma
○Renta Yamakawa1, Tamako Nishimura1, Shiro Suetsugu1 (1. Nara Institute of Science and Technology)
[3P-414]Functional analysis of collagen XVIII in skin wound healing
○Xiaowen Zhang1, Tomoko Yonezawa1, Takahiro Maeba2, Tomonori Ueno3, Mitsuaki Ono1, Takako Sasaki4, Ryusuke Momota1, Kazunori Mizuno3, Shunji Hattori3, Toshitaka Oohashi1 (1. Okayama University, 2. Japanese Red Cross Fukuoka Hospital, 3. Nippi Research Institute of Biomatrix, 4. Oita University)
[3P-415]Characterization of plasma membrane proteins which suppress hepatic stellate cell activation
○Kirara Inoue1,2, Misako Matsubara3,4, Tsutomu Matsubara5, Hayato Urushima5, Hideto Yuasa5, Atsuko Daikoku5, Kazuo Ikeda5, Katsutoshi Yoshizato4, Norifumi Kawada2, Takayuki Suzuki1 (1. Developmental biology, Graduate School of Science, Osaka Metropolitan University, 2. Department of Hepatology, Graduate School of Medicine, Osaka Metropolitan University, 3. Cellular and molecular biology, Graduate School of Veterinary Science, Osaka Metropolitan University, 4. Donated Laboratory for Synthetic Biology, Graduate School of Medicine, Osaka Metropolitan University, 5. Anatomy and Regenerative Biology, Graduate School of Medicine, Osaka Metropolitan University)
[3P-416]Ciliary protein CEP290 can regulate focal adhesion via microtubule system.
○Kazuhiko Matsuo1, Atsuko Ueyama1,2, Kosuke Nishikawa1, Masaki Shigeta1, Yoshiro Nakajima1, Daisuke Kobayashi1, Kenta Yashiro1 (1. Kyoto Pref. Univ. Med., 2. Osaka Univ.)
[3P-417]The chromokinesin Kid forms a homodimer, moves processively along microtubules and transports dsDNA
○Natsuki Furusaki1, Tomoki Kita1, Kyoko Chiba2, Shinsuke Niwa2 (1. Graduate school of Life Science, Tohoku University, 2. Frontier Research Institute for Interdisciplinary Science (FRIS), Tohoku University)
[3P-418]Analysis of role of Abitram in mouse trachea
○Misaki Domoto1, Yui Abe1, Katsuyoshi Takaoka2, Kyosuke Shinohara1 (1. Tokyo University of Agriculture and Technology, 2. Tokushima University)
[3P-419(3PS-05-06)]Thermodynamics and statistical mechanics approach to cellular homeostasis and adaptability
○Yuika Ueda1, Shinji Deguchi1 (1. Osaka Univ.)
[3P-420]Functional analysis of Dpcd on actin fiber structure of tracheal ciliated cells
○Mayu Nakayama1, Ayano Koike1, Kazuaki Nagayama2, Hiroshi Hamada3, Kyosuke Shinohara1 (1. Tokyo University of Agriculture and Technology, 2. Ibaraki University, 3. Institute of Physical and Chemical Research)
[3P-421]Elucidation of the track recognition mechanism of dynein-2
Haoqiang He1, Shintaroh Kubo2, Qianru Lv1, Anthony Roberts3, ○Muneyoshi Ichikawa1 (1. Fudan University, 2. The Univ. of Tokyo, 3. Univ. of Oxford)
[3P-422]Development of an Automated Quantitative Measurement Pipeline for Overlapping Intracellular Membrane Structures Using Deep Learning with ImageJ/Fiji ROIs as Training Data
○Shodai Taguchi1,2, Kenji Irie2, Yasuyuki Suda2,3, Keita Chagi4, Hiroki Kawai4 (1. University of Tsukuba, Ph.D. program in Humanics, 2. University of Tsukuba, Institute of Medicine, Laboratory of Molecular Cell Biology, 3. RIKEN Center for Advanced Photonics, Live Cell Super-Resolution Imaging Research Team, 4. LPIXEL Inc., Research and Development Department)
[3P-423]Degradation of cytokeratins treating with anticancer drugs
○Kodai Inoue1, Taro Tachibana1, Chikako Yokoyama1 (1. Osaka Metro. Univ.)
[3P-424]Defective Interaction of Actin-microtubule with Organelles in Living Cell Expressing INF2 Variants Responsible for FSGS and Peripheral Neuropathy
○Hiroko Ueda1, Quynh Thuy Huong Tran1, Naoyuki Kondo2, Hiroyasu Tsukaguchi1 (1. Second department of Internal Mesicine, Kansai Medical University, 2. Department of Molecular Genetic, Kansai Medikal University)
[3P-425]Evaluation of chaperone function of αB-crystallin on tubulin aggregation at physiological temperatures using fluorescence imaging analysis
○Shinya Horinouchi1,2, Daisuke Inoue3, Shohei Yamamoto4, Eri Ohto-Fujita5, Miho Shimizu2, Toshiyuki Watanabe1, Yoriko Atomi2 (1. Grad. Sch. of Eng., Tokyo Univ. Agric. and Technol., 2. ACRO, Teikyo Univ., 3. Faculty of Design, Kyushu Univ., 4. Grad. Sch. of Pharmaceutical Sci., The University of Tokyo, 5. Faculty of Medical Tech., Teikyo Univ.)
[3P-426]Effect of dynamin-dependent endocytosis on the production of extracellular vesicles
○Sho Takahashi1, Chihiro Nishihara1, Hiroyuki Iwata1, Shusaku Shibutani1 (1. Yamaguchi university)
[3P-427]Development of a novel method to elucidate the regulatory mechanism of microtubule dynamics in neurons
○YURI SAKAI1, Hiroaki MISONO1 (1. Doshisha University)
[3P-428]Transcriptional and epigenetic regulation of Coro1A expression in macrophage
○Yusuke Ando1,2, Hideyuki Takeshima2, Shinya Hasegawa2, Chie Watanabe1, Yukiko Kudo2, Teruaki Oku2 (1. Josai Univ., 2. Hoshi Univ.)
[3P-429]Regulation of cell cycle-dependent changes in microtubule dynamics by EB2 microtubule-associated protein
○Sawako Sasaki1, Keisuke Onishi2, Yukiko Gotoh3, Maiko Higuchi1 (1. Graduate School of Life Science, Rikkyo University, 2. Department of Chemistry and Biotechnology, The University of Tokyo, 3. Graduate School of Pharmaceutical Sciences, The University of Tokyo)
[3P-430]Development of a Micromanipulation System Capable of Applying Large Strains to Individual Cells
○Masahiro Kawakami1, Masaru Kojima1, Atsushi Kubo2, Toshihiko Ogura3, Tatsuo Arai4, Shinji Sakai1 (1. Graduate School of Engineering Science, Osaka University, 2. Graduate School and School of Pharmaceutical Sciences, Osaka University, 3. Graduate School of Medicine, Kyoto University, 4. Center for Neuroscience and Biomedical Engineering, The University of Electro-Communications)
[3P-431]Functional analysis of ES cells expressing mutant STAT3 reported in cancer cells
○Shota Nakamura1, Tomoya Tamaru1, Jin Fujita1, Tadayuki Akagi1 (1. Fukuoka Institute of Technology)
[3P-432]Tetraploidy-linked increase in requirement of TPX2 for cell division control
○Qijiao Wang1, Takahiro Yamamoto1, Ryota Uehara 1,2 (1. Graduate School of Life Science, Hokkaido University, 2. Faculty of Advanced Life Science, Hokkaido University)
[3P-433]CDK12 inhibition drives mitotic catastrophe and genome instability in pancreatic cancer
○Dosuke Iwadate1, Keisuke Yamamoto1, Mitsuhiro Fujishiro1 (1. Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo)
[3P-434]Visualization of gH2A.X signal in liver zonation
○Takako Kogure1, Asako Sakaue-Sawano1, Reiko Takahashi1, Shuichi Shiozaki2, Toshitada Yoshihara2, Michio Tomura3, Atsushi Miyawaki1 (1. RIKEN, 2. Gunma Univ., 3. Osaka Ohtani Univ.)
[3P-435(3PS-03-02)]A synthetic microscale kinetochore establishes a biorientation-like state
○Kohei Asai1, Yuanzhuo Zhou1, Osamu Takenouchi1, Tomoya Kitajima1,2 (1. RIKEN Center for Biosystems Dynamics Research , 2. Graduate School of Biostudies, Kyoto university)
[3P-436]Role of Methionine Aminopeptidase in Muscle Cells
○Shion Osana1, Chengta Tsai1, Naoki Suzuki2, Hiroaki Takada2, Masaki Kaneko1, Katsuhiko Hata1, Ryoichi Nagatomi2 (1. Kokushikan University, 2. Tohoku University)
[3P-437]Effect of vitamin C on the proliferation of epidermal keratinocytes
○Nana Egawa1,2, Hiwatashi Yui1,2, Yoshitaka Kondo1, Akihito Ishigami1,2 (1. Molecular Regulation of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, 2. Department of Biological Sciences, Tokyo Metropolitan University)
[3P-438]The RNA-binding protein Puf5 and the HMGB protein Ixr1 regulate cell cycle-specific expression of CLB1 and CLB2 in Saccharomyces cerevisiae
○Varsha Rana1,2, Megumi Sato1,3, Yasuyuki Suda1,4, Tomoaki Mizuno1, Kenji Irie1 (1. Department of Molecular Cell Biology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan, 2. Doctoral Program in Human Biology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan, 3. Doctoral Program in Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan, 4. Live Cell Super-resolution Imaging Research Team, RIKEN Center for Advanced Photonics, Wako, Saitama, Japan)
[3P-439]Dynamic cell proliferation control coupled with intestinal stem cell differentiation
○Shuji Matsuguchi1, Ayaka Omori1, Yumi Konagaya1 (1. RIKEN)
[3P-440]Effect of intracellular pH change by organic acid addition on E.coli growth
○Mihiro Kobayashi1, Ryosuke Usuda1, Masakazu Kataoka1 (1. Shinshu University)
[3P-441]Nucleolar accumulation of CDK by liquid-liquid phase separation during stationary phase in fission yeast cells
○Mizuki Terauchi1, Takumi Yamatani2, Ayumu Yamamoto1,2 (1. Grad. Sch. Int. Sci. Tech., Shizuoka Univ., 2. Dept.Chem., Fac. Sci., Shizuoka Univ.)
[3P-442(3AS-01-04)]Development of a method for the establishment of cell cycle reporter cells exhibiting diverse time-differences
○Yamato Kasahara1, Sakura Tamamura2, Kentaro Semba1,3, Shinya Watanabe3, Kosuke Ishikawa2 (1. Sch. of Adv. Sci. & Eng., Waseda Univ., 2. Japan Biological Informatics Consortium., 3. Translational Research Center, Fukushima Medical Univ.)
[3P-443]Requirement of Response Regulators Activated by Metabolism in the Sensor Kinase-Independent Manner for Proper Lag Phase of Escherichia coli Growth.
○Genki Hirano1, Yukari Miyake1, Shingo Sugawara1, Kaneyoshi Yamamoto1,2,3 (1. Hosei Univ. Graduate School of Science and Engineering, 2. Hosei Univ. Faculty of Bioscience and Applied Chemistry, 3. Hosei Univ. Research Center for Micro-Nano Technology)
[3P-444]Regulatory mechanism of glucose starvation-induced Cdc2 nucleolar accumulation in fission yeast
○Minakhi Halder1, Katsuyuki Kurashima2, Arisha Ouchi3, Ayumu Yamamoto1,2,3 (1. Graduate School of Science and Technology, Shizuoka University, 2. Graduate School of Integrated Science and Technology, Shizuoka University, 3. Department of Science, Shizuoka University)
[3P-445]Analysis of DNA re-replication initiation process induced by MLN4924
○Sotaro Hanazaki1, Chigusa Naka1, Yuki Kusakawa1, Yasushi Siomi1, Akiyo Hayashi1 (1. Grad. Sch. of Sci., Univ. of Hyogo)
[3P-446]Dri1-Rhs1 complex negatively regulates growth of fission yeast cells at high temperatures
○Yuichi Morozumi1, Yutaka Akikusa1, Kazuhiro Shiozaki1,2 (1. NAIST, 2. UC Davis)
[3P-447(3PS-06-06)]Analysis of Vascular Network Formation Through VEGF-NFAT-Down Syndrome Factor-1 Signaling in the Regulation of Vascular Branching
○Shintaro Funasaki1, Shunsuke Kamei1, Masashi Muramatsu1, Yuichiro Arima2, Koichi Nishiyama3, Takashi Minami1 (1. Mol. and Vascular Biol., IRDA, Kumamoto Univ., 2. Dev. Cardiology, IRCMS, Kumamoto Univ., 3. Vascular and cellular dynamics, Miyazaki Univ.)
[3P-448]The influence of chromosome missegregation in zebrafish early development.
○Akira Matsura1, Kazuya Matsuo2, Nobuyuki Tamaoki3, Tomoya Kotani4, Ryota Uehara1,5 (1. Hokkaido University, Graduate School of Life Science, 2. Faculty of Molecular Chemistry and Engineering, Kyoto Institute of Technology, 3. Research Institute for Electronic Science, Hokkaido University, 4. Department of Biological Sciences, Faculty of Science, Hokkaido University, 5. Faculty of Advanced Life Science, Hokkaido University)
[3P-449]Intracellular metabolite changes by induction of cellular senescence
○Eri Takagi1,2, Ryosuke Hayasaka1,3, Masako Hasebe1, Momo Sato1,3, Yukako Suzuki1,3, Tomoyoshi Soga1,2,3, Akiyoshi Hirayama1,2,3 (1. Keio Univ. Institute for Advanced Biosciences., 2. Keio Univ. Faculty of Environment and Information Studies., 3. Keio Univ. Graduate school of Media and Governance.)
[3P-450]Impact of DL-Homocysteine on Kynurenine Aminotransferases Activity and Muscle Cell Proliferation
○Hiroaki Takada1, Shion Osana2, Ryoichi Nagatomi1 (1. Tohoku university, 2. Kokushikan University)
[3P-451]Vulnerability of human haploid cells to endoplasmic reticulum stress
○Sena Miura1, Sumire Ishihara1,2, Kan Yaguchi1, Kimino Sato1, Ryota Uehara1,2 (1. Graduate School of Life Science, Hokkaido University, 2. Faculty of Advanced Life Science, Hokkaido University)
[3P-452(3AS-16-06)]Novel positive regulator of mammalian Hedgehog signaling via phosphorylation of GLI2/GLI3
○Saishu Yoshida1,2, Akira Kawamura2, Katsuhiko Aoki3, Pattama Wiriyasermkul4,5, Shinya Sugimoto6,7,8, Junnosuke Tomiyoshi2, Ayasa Tajima4,9, Yamato Ishida10, Yohei Katoh10,11, Takehiro Tsukada1, Yousuke Tsuneoka12, Kohji Yamada2, Shushi Nagamori4,5, Kazuhisa Nakayama10, Kiyotsugu Yoshida2 (1. Dept. of Biomolecular Science, Toho Univ., 2. Dept. of Biochemistry, The Jikei Univ. School of Medicine, 3. Radioisotope Research Facilities, The Jikei Univ. School of Medicine, 4. Center for SI Medical Research, The Jikei Univ. School of Medicine, 5. Dept. of Laboratory Medicine, The Jikei Univ. School of Medicine, 6. Dept. of Bacteriology, The Jikei Univ. School of Medicine, 7. Center for Biofilm Science and Technology, The Jikei Univ. School of Medicine, 8. Laboratory of Amyloid Regulation, The Jikei Univ. School of Medicine, 9. Dept. of Molecular Biology, The Jikei Univ. School of Medicine , 10. Dept. of Physiological Chemistry, Graduate School of Pharmaceutical Sciences, Kyoto Univ., 11. Hiroshima Univ. Genome Editing Innovation Center, 12. Dept. of Anatomy, Faculty of Medicine, Toho Univ.)
[3P-453]Phosphorylation mechanism of key factor Hxk2 in metabolic conversion
○Kazuki Nonaka1, Minako Fukase1, Kohei Nishimura1, Keisuke Obara1, Takumi Kamura1 (1. Dept. of Biol. Sci., Grad. Sch. of sci., Nagoya Univ.)
[3P-454]Mechanism of regulation of axon regeneration by AAK-2 - UNC-51 - UNC-14 in C. elegans.
○Minari Matsumoto1, Kunihiro Matsumoto1, Naoki Hisamoto1 (1. Div. of Bio. Sci., Grad. School of Sci., Nagoya Univ.)
[3P-455(3PS-12-06)]Phosphorylation of the carboxyl terminus of the S. pombe arrestin Aly3 suppresses endocytosis of the hexose transporter Ght5
○Yusuke Toyoda1, Fumie Masuda1, Shigeaki Saitoh1 (1. Kurume Univ.)
[3P-456]Quantitative investigation of Akt isoforms’ temporal dynamics and their regulation of signaling pathway by developing analytical platform using optogenetics and mathematical model
○Yuka Sekine1, Genki Kawamura1, Akito Kusaka2, Takeaki Ozawa1 (1. Dept. of Chem., Grad. Sch. of Sci., The Univ. of Tokyo, 2. Dept. of Physics, Grad. Sch. of Sci., The Univ. of Tokyo)
[3P-457]Androgen receptor Ser-815 phosphorylation in human prostate cancer cell lines
○Yuki Kawasaki1, Reo Matsuzaki1, Aoi Nagashima1, Masahiko Negishi2 (1. Lab. of Public Health, Fac. of Pharm., Takasaki Univ. of Health & Welfare, 2. NIEHS/NIH)
[3P-458(3AS-04-06)]A ubiquitin decoder that enhances the targeted degradation of cIAP1
○Yoshino Akizuki1, Yusuke Sato2, Fumiaki Ohtake1 (1. Hoshi Univ., 2. Tottori Univ.)
[3P-459(3PS-17-04)]Development of chemogenetic tools for temporal control of mTORC1 activity in living cells
○Naoki Komatsu1, Atsushi Miyawaki1,2 (1. RIKEN CBS, 2. RIKEN RAP)
[3P-460]Theory and Simulation of Chemo-Mechanical Coupling in Cell-ECM Adhesion Feedback Dynamics
○Eiji Matsumoto1, Shinji Deguchi1 (1. Div. of Bioeng., Grad. Sch. of Eng. Sci., Osaka Univ.)
[3P-461]Investigation of the role of Akt2 in the regulation of glycolysis through an optogenetics approach
○Genki Kawamura1, Takeaki Ozawa1 (1. The Univ. Tokyo)
[3P-462(3AS-15-07)]Analysis of the proteome changes during the development of 5-Fluorouracil Chemoresistance in Colorectal Cancer Cells, focusing on the Methyl Proteome.
○Isaac Micallef1,2, Byron Baron2, Norie Araki1,3 (1. Department of Tumor Genetics and Biology/Molecular Genetics, Graduate School of Medical Sciences, Kumamoto University, 2. Centre of Molecular Medicine and Biobanking, University of Malta, 3. Faculty of Life Sciences, Kumamoto University)
[3P-463]SMAD2 ubiquitination regulates skeletal muscle mass and fibrotic degeneration
○Yuki Yamasaki1, Keita Sakamoto1, Shunki Yashiro1, Akiko Kondow2, Atsushi Kubo3,4, Keisuke Hitachi5, Masafumi Inui1 (1. Laboratory of Animal Regeneration Systemology, Department of Life Sciences, School of Agriculture, Meiji University, 2. Advanced Comprehensive Research Organization, Teikyo University, 3. Laboratory of Stem Cell Regeneration and Adaptation, Graduate School of Pharmaceutical Sciences, Osaka University, 4. Department of Developmental Neurobiology, Institute of Development, Aging and Cancer, Tohoku University, 5. Division for Therapies against Intractable Diseases, Institute for Comprehensive Medical Science (ICMS), Fujita Health University,)
[3P-464]Analysis of Chemotaxis Regulation through GPCR Phosphorylation
○Yuna Usami1, Yusuke Ono1, Yoichiro Kamimura2, Tetsuya Muramoto1 (1. Toho Univ., 2. Nara Medical Univ.)
[3P-465]Cluster mapping of molecular complexes at clathrin coats by IRIS, multi-target super-resolution microscopy
○Tai Kiuchi1 (1. Dept. of Pharmacol., Kyoto Univ. Grad. Sch. of Med.)
[3P-466]Functional analysis of TC-PTP/PTPN2 and SH-PTP2/PTPN11 in the inhibition of metastatic melanoma proliferation by the phorbol ester TPA
○Yuki Akamatsu1, Mami Onishi1, Taiki Nagano2, Shinji Kamada1,2, Tetsushi Iwasaki1,2 (1. Dept. of Biol., Grad. Sch. of Sci., Kobe Univ., 2. Biosig. Res. Ctr., Kobe Univ.,)
[3P-467]Identification of novel ERK substrates by yeast three hybrid screening
○Yuto Ishii1,2, Seina Ohe1, Yuji Kubota1, Mutsuhiro Takekawa1 (1. Div. of Cell Sig. & Mol. Med., Inst. of Med. Sci., Univ. of Tokyo, 2. Dept. of Comp. Biol. & Med. Sci., Sch. of Front. Sci., Univ. of Tokyo)
[3P-468]Regulatory mechanism that oprerates in responce to hyperosmolarity
○Tsutomu Kishi1, Yuki Ohara1 (1. Nihon University)
[3P-469]Phosphorylation of Rgc2 that is independent of Hog1
○RUYUE CHANG1, TSUTOMU KISHI1 (1. NIHON UNIWERSITY)
[3P-470]Analysis of insulin receptor substrates 4 and PI3K in the activation of mTORC1 by amino acids
○Kakeru Masada1, Chiaki Ishii1, Masatoshi Maki1, Hideki Shibata1, Terunao Takahara1 (1. Dept. of Applied Biosci., Grad. Sch. of Bioagric., Nagoya Univ.)
[3P-471]Cell size feedback mechanism for propagating cell-to-cell signaling in Dictyostelium discoideum
○Yukihisa Hayashida1, Chikoo Oosawa1, Takuo Yasunaga1, Yusuke V. Morimoto1 (1. Kyushu Institute of Techology)
[3P-472]Evaluation of Adrenergic Biosensors Using the Glucose Signaling Pathway in S.pombe
○Takumi Okamoto1, Toshiya Osada1 (1. Tokyo Institute of Technology)
[3P-473]Functional analysis of extracellular vesicles (EVs) from algae
○Ayumi Sakurai1, Hiroshi Takemori1 (1. Gifu Univ.)
[3P-474]Inhibition of RET kinase activity by cysteine containing peptide
○Ryogen Hosoda1, Yoshiyuki Kawamoto1, Kozue Takeda1 (1. Chubu University)
[3P-475]Activation of the CAMKK2-AMPK-ULK1 signalling pathway by the glycation product dihydropyrazine
○Shinji Takechi1, Madoka Sawai2, Yuu Miyauchi1 (1. Fac. Pharmaceut. Sci., Sojo Univ., 2. Sch. Pharm., at Fukuoka. Int. Univ. Health & Welfare)
[3P-476]Soluble guanylate cyclase subunit GUCY1A2 is associated with inflammatory phenotype in senescent cells
○Ryota Kobori1,2, Soichiro Kumamoto1, Tomohisa Baba1, Yasuhiro Nakano1,3, Yoshikazu Johmura1,3 (1. Cancer Res. Inst., Kanazawa Univ., 2. Sch. Biol. Sci. Tech., Col. Sci. Engr., Kanazawa Univ., 3. Inst. Front. Sci. Initiative, Kanazawa Univ.)
[3P-477]Microbial Production of Plant Alkaloids and Exploration of Synthetic Metabolic Pathways
○Koko Nakata1, Toshiki Saito2, Christopher J. Vavricka3, Shunsuke Takahashi1 (1. Div. Life Sci. Eng., Sch. Sci. Eng., Tokyo Denki Univ., 2. Dept. Life Sci. Eng., Grad. Sch. Sci. Eng., Tokyo Denki Univ., 3. Dept. Life Eng., Grad. Sch. Eng., Tokyo Univ. Agric. Tech.)
[3P-478]The Potential of a Novel Acne Treatment Using Extracellular Vesicles Targeting TRP Channels
○daichi ito1, Hiroshi Takemori2 (1. Gifu Univ, 2. Gifu Univ graduate school)
[3P-479]Screening of crude drug extracts having the inhibitory function of IL-18 activation by using enzyme-linked immunosorbent assay (ELISA) for detecting active human IL-18 protein.
○Hiroki Kamino1, Hitoshi Kotani2, Yuko Nariai1, Takeshi Urano1,3 (1. R&D Ctr. Vac. and Therap. Abs., Shimane Univ., 2. Dept. Immunol., Fac. Med., Shimane Univ., 3. mAbProtein Co. Ltd.)
[3P-480]Functional changes of mice skeletal muscle in heat acclimation
○Yuka Kudo1, Nozomi Yazawa1, Yuho Mizuseki1, Keigo Murata1, Taku Nedachi1 (1. Graduate School of Life Sciences, Toyo University)
[3P-481]Elucidation of the molecular mechanism underlying TNF-α-, and IL-1β-increased expression of matrix metalloproteinase in inflammatory synovial tissue caused by temporomandibular joint osteoarthritis
○Karen Abe1,2, Seiji Yokota1, Kanna Asanuma2, Emiko Kikuchi2, Naoyuki Chosa1, Kazuro Satoh2, Akira Ishisaki1 (1. Division of Cellular Biosignal Sciences, Department of Biochemistry, Iwate Medical University, 2. Division of Orthodontics, Department of Developmental Oral Health Science, Iwate Medical University)
[3P-482]Evaluation of Estrogenic Activity of Steroidal Alkaloids in Solanum plants
○Kenichiro Hoashi1, Kentaro Nishi1, Ryoiti Kiyama1 (1. Kyushu Sangyo University)
[3P-483]Analysis of stress response mechanisms to centrosome amplification
○Shunnosuke Honda1, Yutaka Takeda1, Takumi Chinen1, Yusuke Taira2, Natsuki Shinoda2, Masayuki Miura2, Daiju Kitagawa1 (1. Dept. of Physiol. Chem., Grad. Sch. of Pharm. Sci., Univ., of Tokyo, 2. Dept. of Genet., Grad. Sch. of Pharm. Sci., Univ., of Tokyo)
[3P-484]Dissecting systemic regulation of tumor-suppressive cell competition
○Shino Ihara1, Bungo Kakemura2, Tomoe Kobayashi3, Makoto Matsuyama3, Tatsushi Igaki1,2 (1. Graduate School of Pharmaceutical Sciences, Kyoto University, 2. Graduate School of Biostudies, Kyoto University, 3. Division of Molecular Genetics, Shigei Medical Research Institute)
[3P-485]High throughput hiPSC cardiomyocyte beating evaluation using PAC gene which is an optical manipulation tool to generate cAMP in cells
○Hirofumi Horai1, Sunao Hisada1, Masumi Takebe2, Shigeru Matsunaga2 (1. Hamamatsu Photonics K.K. Systems Division, 2. Hamamatsu Photonics K.K. Central Research Laboratory)
[3P-486]Structural basis for agonist recognition by b3-adrenergic receptor
○Ikko Nureki1, Kazuhiro Kobayashi1, Wataru Shihoya1, Osamu Nureki1 (1. The University of Tokyo)
[3P-487]PERK plays a crucial role in cell competition in Drosophila.
○Sakura Ishihara1, Rina Nagata1, Shu Kondo2, Kuniaki Saito3, Tatsushi Igaki (1. Kyoto University, 2. Tokyo University of Science, 3. National Institute of Genetics)
[3P-488]Mechanisms of selective killing of breast cancer cells by plasma-activated Ringer’s lactate solution
○Ayako Tanaka1, Masaaki Mizuno2, Kenji Ishikawa1, Camelia Miron1, Hiroshi Hashizume1, Yasumasa Okazaki2, Shinya Toyokuni2, Kae Nakamura2, Hiroaki Kajiyama2, Masaru Hori1, Hiromasa Tanaka1 (1. Center for Low-temperature Plasma Sciences, Nagoya University, 2. Nagoya University Graduate School of Medicine)
[3P-489(3PS-13-02)]Impaired YME1L-mediated mitochondrial proteostasis triggers mitochondrial stress signalling and orchestrates ferroptotic resistance
○Mashun Onishi1, Thomas Langer1 (1. Max Planck Institute for Biology of Ageing)
[3P-490]Disorder of ribosomal biogenesis and induction of nucleolar stress responses caused by deficiency of AAA-ATPase NVL2
○Keiichi Izumikawa1, Yuuya Hirooka1, Sotaro Miyao1, Masanori Tamura1, Sayuri Motonaga1, Masami Nagahama1 (1. Meiji Pharmaceutical University)
[3P-491]Genetic Analysis of the Mechanism of Eiger/TNF-Grnd/TNFR Activation in Tumor-Suppressive Cell Competition
○Shuiwo Mach Mak1, Asuka Catherine Kido2, Haolin Xie1, Senri Sakaino4, Tomoya Ueda1, Tomoe Kobayashi5, Makoto Matsuyama5, Kiichiro Taniguchi1, Tatsushi Igaki1,2,3 (1. Grad. Sch. Bio., Kyoto Univ. , 2. Grad. Sch. Pharm., Kyoto Univ. , 3. Fac. Pharm., Kyoto Univ. , 4. Fac. Sci., Kyoto Univ., 5. Div. of Mol. Genet., Shigei Med. Res. Inst.)
[3P-492]Inhibitory effect of kynurenine on ferroptosis in pulmonary vascular endothelial cells and monocytes
○Yuchen Sun1, Kosuke Saito1, Toshiko Momiyama1, Ayaka Yoshida1, Noriaki Arakawa1, Ruri Kikura-Hanajiri1 (1. National Institute of Health Sciences)
[3P-493]DEAD/H box 17 (DDX17) enhances deregulated E2F1 activity
○Mariana Fikriyanti1, Kiyoshi Ohtani1 (1. Dept. of Biomed. Chem., Grad. School of Science and Tech., Kwansei Gakuin University)
[3P-494]Auranofin as a therapeutic strategy aganist acute myeloid leukemia
○Wonwoo Choi1, Sanggyu Lee1 (1. Kynugpook National University)
[3P-495]Genetic analysis of Eiger/TNF-Grnd/TNFR-JNK activation mechanism in tumor-suppressive cell competition
○Asuka Catherine Kido1, Shuiwo Mach Mak2, Haolin Xie2, Senri Sakaino3, Haruhiko Sato1, Mai Nakamura2, Ryo Matsumoto2, Jiaqi Li2, Weiran Ye2, Tomoe Kobayashi4, Makoto Matsuyama4, Shu Kondo5, Keita Miyoshi6, Kuniaki Saito6, Kiichiro Taniguchi2, Tatsushi Igaki1,2 (1. Grad. Sch. and Fac. of Pharm. Sci., Kyoto Univ., 2. Grad. Sch. of Biostudies, Kyoto Univ., 3. Fac. of Sci., Kyoto Univ., 4. Div. of Mol. Genet. Shigei Med. Res. Inst., 5. Dept. of Biol. Sci. & Tech., Tokyo Univ. of Sci., 6. Invertbr. Genet. Lab, Natl. Inst. of Genet.)
[3P-496]Specific ceramide molecular species are involved in regulating necroptosis induction
○Hikari Nishisaka1, Yuri Ogiso1, Miyu Kato1, Ryuji Yamazawa1, Masaya Matsuda1, Toshiyuki Yamaji2, Kentaro Hanada3, Wataru Sakamoto4, Daniel Canals4, Yusuf Hannun4, Kiyoshi Ito1, Takeshi Nabe1, Kazuyuki Kitatani1 (1. Setsunan Univ., 2. Juntendo Univ., 3. National Institute of Infectious Diseases, 4. Stony Brook University Stony Brook Cancer Center)
[3P-497]Apoptosis Inducing Effect of Vietnamese Plant-Derived Compound Pristimerin or Tanshinone ⅡA on Human Gastric Cancer Cell Lines
○Kenji Takeuchi1, Ayaka Ozaki1, Mitsuki Yasui1, Daigo Nishitani1, Kentaro Nishida1 (1. Setsunan University)
[3P-498]The induction of p53-dependent extrinsic apoptosis through the inhibition of iron/heme metabolism by gallic acid in breast cancer cells
○Dong Young KANG1, Kyoung-Jin Jang2 (1. Konkuk University, 2. Sejong University)
[3P-499]Protocatechuic acid alkyl ester (PCA) derivative effectively induces multiple anticancer effects in non-small cell lung cancer cells
○Yun Kyeong Kwon1, Kyoung Jin Jang1 (1. Sejong University)
[3P-500]Aristolochic acid induces acute toxicity via DNA adduct formation in proximal tubular cells
○Miyu Komatsu1, Takeshi Funakoshi1, Toshihiko Aki1, Kana Unuma1 (1. Institute of Science Tokyo)
[3P-501]Elucidation of CB1 Receptor-Independent Mechanisms of Neuroprotection and Neurotoxicity Induced by Cannabinoids
○Kazuaki Mori1, Akinobu Togo2, Kouta Yamashita3, Taishi Umezawa3, Keisuke Ohta2, Chihiro Nozaki4, Toru Asahi1,5, Kosuke Kataoka5,6 (1. Grad. Sch. Adv. Sci. Eng., Waseda Univ., 2. Adv. Imag. Res. Cent., Kurume Univ. Sch. Med., 3. Grad. Sch. Agri., Tokyo Univ. Agri. Tech., 4. Glob. Cent. Sci. Eng., Waseda Univ., 5. Comp. Res. Org., Waseda Univ., 6. Grad. Sch. Eng., Tokyo Univ. Agri. Tech.)
[3P-502]Analysis of an engineered cell elimination system for cell therapy
○satoshi yoshimoto1, Zhuohao Yang2, Takashi Kamatani3, Akiko Takahashi6, Shigeo S Sugano4, Shinya Sakuma7, Yoshitaka Shirasaki2, Satoshi Yotsumoto5, Kosuke Dodo1 (1. RIKEN, 2. Tokyo Univ., 3. Tokyo Medical and Dental Univ., 4. National Institute of Advanced Industrial Science and Technology, 5. Tokyo University of Pharmacy and Life Sciences, 6. Japanese Foundation For Cancer Research, 7. Kyushu Univ.)
[3P-503]Development of subcellular local heating technology
toward heat shock protein studies
○Dilini Nisansala Hettimudalige1, Kavindu Deshan Basnayake Mudiyanselage1, Takeru Yamazaki2, Kyoko Nomura2, Satoshi Arai2 (1. Division of Nano Life Science, Kanazawa University, 2. Nano Life Science Institute (WPI-NanoLSI), Kanazawa University)
[3P-504]Enzyme-free cell harvesting technology - temperature-responsive cell cultureware UpCell®
○Asumi Yoshihara1, Eriko Ikeda1, Yuzo Kasuya1 (1. CellSeed Inc.)
[3P-505]Sub-micron spatial resolution bioimaging with Widefield O-PTIR microscopy
○Naoki Baden1, Norio Urayama1, Michael K.F. Lo2, Eoghan Dillon2, Mustafa Kansiz2, Craig Prater2 (1. Nihon Thermal Consulting, Co., Ltd., 2. Photothermal Spectroscopy Corp.)
[3P-506]Effect of dispersants on macrophage response to multi-walled carbon nanotubes
○Akihiro Moriyama1 (1. AIST)
[3P-507]Research on the Property Observation of Crystallized Proteins Expressed in Living C. elegans Cells and Development of Crystal Structure Control Technique
○Ibuki Sugawara1, Yoichi Shinkai2, Masahiro Kuramochi1 (1. Dept. of Quant. Sci. Eng., Grad. Sch. of Sci., Univ. of Ibaraki, 2. Biomedical Research Institute, AIST)
[3P-508]Secretion of sFlt1 by macrophages is associated with the nuclear translocation of cathepsin B
○Ren Ozawa1, Koumei Shirasuna1 (1. Tokyo university of agriculture)
[3P-509]Creating Membraneless Protocells with Earth-abundant Transition Metal Catalysts
○Chen Chen1, Tony Z. Jia2,3, Ryuhei Nakamura1,2 (1. Biofunctional Catalyst Research Team, RIKEN CSRS, 2. Earth-Life Science Institute, Tokyo Institute of Technology, 3. Blue Marble Space Institute of Science)
[3P-510]Calcium ions induce the aggregation of highly phosphorylated Tau.
○Toru Tanaka1, Sachiyo Ohashi1, Shunsuke Kobayashi1 (1. Nihon university)
[3P-511]Automation of Detection and Counting of Microbial Colonies on Agar Plates
○Daichi Arima1, Shuto Takahashi1, Yukie Sakai1, Hiroyuki Kurata1, Kazuhiro Maeda1 (1. Kyushu Institute of Technology)
[3P-512]Cytomorphological Characteristics of the Liver in the Iberian ribbed Newt(Pleurodeles waltl): Part of an Online Atlas Project for Newts
○Dalia Mohamedien1,2, Kazuko Okamoto1, Toshinori Hayashi1 (1. Amphibian Research Center, Hiroshima University, Japan, 2. Histology Department, Faculty of Veterinary Medicine, South Valley University, 83523, Egypt)
[3P-513]Investigation of recycling-endocytosis regulation by the Arf inhibitor M-COPA
○Aika Kobayashi1, Arisa Sugaya1, Yuta Semba1, Takatsugu Murata2, Hisazumi Tsutsui2, Daiki Usukura2, Isamu Shiina2, Shunsuke Takahashi1, Yukitoshi Nagahara2 (1. Dept. of Sci. Eng., Tokyo Denki Univ., 2. Faculty of Sci., Tokyo Univ. of Sci.)
[3P-514]TDA As Image Analysis Tool (TAIAT) Project: "Usable" TDA for bioresearch
○Haruhisa Oda1 (1. Univ. Tokyo)
[3P-515]Desiccation tolerance of the Caenorhabditis elegans expressing the ice-binding protein
○Daiki Shimose1, Ryouhei Kuriyama1, Yuka Ikemoto2, Masahiro Kuramochi1 (1. Dept. of Quant. Sci. Eng., Grad. Sch. of Sci., Univ. of Ibaraki, 2. Japan Synchrotron Radiation Research Institute (JASRI))
[3P-516]Functional analysis of Syntaxin3 in the formation of epidermal cornified cell envelope
○Seira Shiokawa1, Yohei Hirai1 (1. Dept. biomedical, Sch. Sci. Technol., Kwansei Gakuin Univ.)
[3P-517]Investigation of LC3-BII induction under cold stress conditions
○Kaito Horiuchi1, Hiromi Nobe2, Akira Shobo2, Shunsuke Takahashi1, Yukitoshi Nagahara1 (1. Dept. of Sci. Eng., Tokyo Denki Univ., 2. Faculty of Health Science Technology., Bunkyo Gakuin University.)
[3P-518]Enhancing Macrophage Phagocytosis of Klebsiella pneumoniae with Antimicrobial Peptides
○Yen-Tong Chen1,3, Ying-Tsong Chen1,2, Yi-Chyi Lai3 (1. Graduate Institutes of Genomics and Bioinformatics, National Chung Hsing University, Taiwan, 2. Institute of Molecular and Genomic Medicine, National Health Research Institutes, Taiwan, 3. Department of Microbiology and Immunology, Chung Shan Medical University, Taiwan)
[3P-519]Investigating intracellular GTP level on cellular processes using a single fluorescence-based FLIM indicator
○Loan Thi Ngoc Nguyen1, Cong Quang Vu2, Satoshi Arai2 (1. Division of Nano Life Science, Kanazawa University, 2. Nano Life Science Institute (WPI-NanoLSI), Kanazawa University)
[3P-520]Molecular Basis of Cellular Senescence in Urban Particular Matter-Exposed Retinal Pigment Epithelial Cells
○Ye Bin Kim1, Beom Su Park1,2, JaeHun Cheong1, Yung Hyun Choi2 (1. Pusan National University, 2. Dong-eui University college of korean medicine)
[3P-521]Quantify the correlation between signal transduction and chemotaxis response during aversive stimulus acceptance as measured by FRET
○Tomoya Matsushima1, Yumiko Uchida1, Akihiko Ishijima1, Hajime Fukuoka1 (1. Osaka university)
[3P-522]Elucidating the role of TRPA1 in skin inflammation induced by p-phenylenediamine
○Asuka Izawa1, Shunsuke Takahashi1, Yukitoshi Nagahara1 (1. Dept. of Sci. Eng., Tokyo Denki Univ.)
[3P-523]Aryl Hydrocarbon Receptor-Dependent Pulmonary Arterial Remodeling in Pulmonary Arterial Hypertension
○Makoto Okazawa1, Akiko Yamagishi1, Takeshi Masaki1, Tomohiko Ishibashi1, Tadakatsu Inagaki1, Ryotaro Asano1, Hidetaka Kosako2, Yoshikazu Nakaoka1 (1. National Cerebral and Cardiovascular Center, 2. Institute of Advanced Medical Sciences, Tokushima University)
[3P-524]Analysis of the dynamics of chloroplasts and photosynthetic activity in animal cultured cells
○Yayoi Inui1, Ryota Aoki1, Yoji Okabe1, Mayuko Sato2, Noriko kamiya Takeda2, Kiminori Toyooka2, Koki Sawada1, Hayato Mortita1, Baptiste Genot1, Shinichiro Maruyama1, Tatsuya Tomo3, Kintake Sonoike4, Sachihiro Matsunaga1 (1. The University of Tokyo, 2. RIKEN, 3. Tokyo University of Science, 4. Waseda University)
[3P-525]Analysis of the Fluorescent Substrates of the Human Hepatocyte Transporter OATP1B3
○Seiwa Tedokon1, Risa Eto1, Yasunari Yunoki1, Kazuhiro Shiozaki1,2, Shota Takumi1,2, Masaharu Komatsu1,2 (1. Graduate School of Agriculture, Forestry and Fisheries, Kagoshima University, 2. The United Graduate School of Agricultural Sciences Kagoshima University)
[3P-526]Comprehensive Analysis of Stress-Dependent Subcellular Localization Changes in Proteins
○Takahide Matsushima1, Yuki Naito1, Tomoki Chiba1, Ryota Kurimoto1, Koji Ochiai2, Koichi Takahashi2, Naoki Goshima3,4, Hiroshi Asahara1 (1. Department of Systems BioMedicine, Institute of Science Tokyo, 2. Laboratory for Biologically Inspired Computing, RIKEN Center for Biosystems Dynamics Research, 3. Molecular Profiling Research Center for Drug Discovery, National Institute of Advanced Industrial Science and Technology, 4. Department of Human Science, Faculty of Human Science, Musashino University, Tokyo, Japan)
[3P-527]Development of a Microdevice for Fusion of Cells with Large DNA-Encapsulated Uniform-Sized Liposomes and Subsequent Time-Lapse Imaging
○Chihiro Akiyama1, Kento Tsurumoto1, Osamu Kurosawa1, Hidehiro Oana1 (1. Dept. of Mech. Eng., Grad. Sch. of Eng., Univ. of Tokyo)
[3P-528]Live Cell Imaging of cAMP-induced Calcium Responses Using a Calcium Biosensor GCaMP3 in Dictyostelium
○dahyeon Kim1,2, Taeck Joong Jeon1,2 (1. Department of Integrative Biological Sciences & BK21 FOUR Educational Research Group for Age-associated Disorder Control Technology, Chosun University, Gwangju 61452, Republic of Korea, 2. Research Institute of Chosun Natural Science & CSU G-LAMP Project Group, Chosun University, Gwangju, 61452, Republic of Korea)