[27-10-pm] Science for Drug Formulation 1/Genetic drug delivery system | The 146th Annual Meeting of the Pharmaceutical Society of Japan (Osaka)

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Oral Presentation(E) Pharmaceutical Health Care and Sciences

[27-10-pm]Science for Drug Formulation 1/Genetic drug delivery system

Fri. Mar 27, 2026 3:30 PM - 5:30 PM JST
Fri. Mar 27, 2026 6:30 AM - 8:30 AM UTC

Room 10 (C303, Bldg. 2, Area 2 [3F])

Chair: Shingo Ito, Shinya Uchida

3:30 PM - 3:42 PM JST(6:30 AM - 6:42 AM UTC)

[27-10-pm11S]Intracerebral delivery of edaravone ionic liquid via intranasal administration and its effectiveness on cerebral ischemia/reperfusion injury

○Kotone Yoshimura¹, Tatsuya Fukuta¹, Rikuto Ihara¹, Mayumi Ikeda¹, Kazunori Kadota¹ (1. Sch. Pharm. Sci., Wakayama Med. Univ.)

3:42 PM - 3:54 PM JST(6:42 AM - 6:54 AM UTC)

[27-10-pm12S]Analysis of microglial responses to extracellular vesicles derived from inflammation-induced brain cells

○Hiro Matsushita¹, Takuto Namba¹, Ayako Matsuo¹, Yasuhiro Kosuge², Takanori Kanazawa^1,3,4 (1. Sch. Pharm. Sci., Tokushima Univ, 2. Sch. Pharm, Nihon Univ, 3. Grad. Sch. Biomed. Sci., Tokushima Univ, 4. Inno. Res. Cent. DDS., Tokushima Univ)

3:54 PM - 4:06 PM JST(6:54 AM - 7:06 AM UTC)

[27-10-pm13S]Design and evaluation of lipid nanoparticles with enhanced mRNA delivery into dendritic cells and epidermis via membrane fluidity modulation

○Tsubasa Koga¹, Takanori Kanazawa^1,2,3 (1. Sch. Pharm. Sci., Tokushima Univ., 2. Grad. Sch. Biomed. Sci., Tokushima Univ., 3. Inno. Res. Cent. DDS., Tokushima Univ.)

4:06 PM - 4:18 PM JST(7:06 AM - 7:18 AM UTC)

[27-10-pm14S]Impact of administration route on pancreatic and islet distribution and mRNA expression regions of DOPC-containing lipid nanoparticles

○Yuta Takeuchi¹, Hayato Hanayama¹, Yukiko Kaneko², Takanori Kanazawa^1,3,4 (1. Sch. Pharm. Sci., Tokushima Univ., 2. Grad. Sch. Pharm. Sci., Univ. Shizuoka, 3. Grad. Sch. Biomed. Sci., Tokushima Univ., 4. Inno. Res. Cent. DDS., Tokushima Univ.)

4:18 PM - 4:30 PM JST(7:18 AM - 7:30 AM UTC)

[27-10-pm15S][Withdrawn]

4:30 PM - 4:42 PM JST(7:30 AM - 7:42 AM UTC)

[27-10-pm16]Chitosan-Based Non-Viral Nanoparticle Vectors for Type VII Collagen Gene Delivery in Gene Treatment of Dystrophic Epidermolysis Bullosa

○Yan-Jye Shyong¹, Chao-Kai Hsu², Chien-Hung Yu³, Jada Paige Elfridge¹, John McGrath⁴ (1. School of Pharmacy, National Chung Kung University , 2. Department of Dermatology, National Cheng Kung University, 3. Department of Biochemistry and Molecular Biology, Nation Cheng Kung University, 4. Department of Molecular Dermatology, King’s College London)

4:42 PM - 4:54 PM JST(7:42 AM - 7:54 AM UTC)

[27-10-pm17S]Development and Characterization of a Simian Adenovirus–Based Vaccine Vector

○fuka okumura¹, Sora Tokuoka², Naoya Nagata¹, Rika Onishi¹, Aoi Shiota¹, Fuminori Sakurai^3,1, Kahori Shimizu^1,2, Hiroyuki Mizuguchi^1,2,4,5,6,7 (1. Grad. Sch. Pharm. Sci, Univ. Osaka., 2. Sch. Pharm. Sci, Univ. Osaka., 3. Sch. Pharm. Sci, Univ. Kindai., 4. Natl. Inst. Biomed. Innov. Health Nutr., 5. MEIC, Univ. Osaka., 6. OTRI, Univ. Osaka., 7. CiDER, Univ. Osaka.)

4:54 PM - 5:06 PM JST(7:54 AM - 8:06 AM UTC)

[27-10-pm18S]Improving the Efficiency of Intracellular mRNA Delivery Using Nucleic Acid–Loaded Coacervates

○Ayumi Kikkawa¹, Yoshimasa Kawaguchi¹, Imanishi Miki¹, Shiroh Futaki² (1. Inst. Chem. Res., Kyoto Univ., 2. Grad. Sch. Pham. Sci., Kyoto Univ.)

5:06 PM - 5:18 PM JST(8:06 AM - 8:18 AM UTC)

[27-10-pm19S]CRISPR-Cas9 RNP delivery systems comprising tannic acid and fine-tuned boronic acid-conjugated polymers for kidney-selective in vivo genome editing

○Toshizumi Chino^1,2, Takumi Matsuo^1,2, Yuto Honda^1,2,3, Yuriko Osakabe¹, Haochen Guo³, Kyohei Muguruma^1,2, Yutaka Miura^1,2, Nobuhiro Nishiyama^1,2,3 (1. Dept. of Life Sci. and Tech., Science Tokyo, 2. Lab. for Chem. and Life Sci., Science Tokyo, 3. iCONM)

5:18 PM - 5:30 PM JST(8:18 AM - 8:30 AM UTC)

[27-10-pm20S]Preparation of cationic polymer-containing microfluidic nanobubbles and miRNA delivery

○Taiki Yamaguchi¹, Yoko Endo-Takahashi^1,2, Hayato Okuyama², Shiori Nate², Saki Yoshida², Yuni Onishi², Yoichi Negishi^1,2 (1. Grad. Sch. Pharm., Tokyo Univ. Pharm. Life Sci., 2. Sch. Pharm., Tokyo Univ. Pharm. Life Sci.)

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