The 146th Annual Meeting of the Pharmaceutical Society of Japan (Osaka)
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Session Details

Oral Presentation(E) Pharmaceutical Health Care and Sciences

[27-12-am]Pharmaceutics 3, Transpoters/ADME

Fri. Mar 27, 2026 9:30 AM - 11:30 AM JST
Fri. Mar 27, 2026 12:30 AM - 2:30 AM UTC
Room 12 (C403, Bldg. 2, Area 2 [4F])
Chair: Yuriko Higuchi, Kita Tomoko
9:30 AM - 9:42 AM JST(12:30 AM - 12:42 AM UTC)

[27-12-am01S]Development of a novel functional analysis method for monocarboxylate transporter 7

○Misato Kunieda1, Sayaka Natori1, Keisuke Sato1, Kei Higuchi2, Hisanao Kishimoto1, Katsuhisa Inoue1 (1. Sch. Pharm., Tokyo Univ. Pharm., 2. Fac. Pharm., Toho Univ.)
9:42 AM - 9:54 AM JST(12:42 AM - 12:54 AM UTC)

[27-12-am02S]Effects of microplastic particle size and surface modification on drug metabolizing enzymes

○Mayuki Nakayama1, Atsushi Kawase1, Mimi Nakao1, Yunsik Woo1, Yuya Haga2, Yasuo Tsutsumi2, Hiroaki Shimada1, Fuminori Sakurai1 (1. Fac. of Pharm,Kindai Univ., 2. Grad. Sch. of Pharm. Sci. of Osaka Univ.)
9:54 AM - 10:06 AM JST(12:54 AM - 1:06 AM UTC)

[27-12-am03S]Metabolism and renal toxicity of Methotrexate in chimeric mice with humanized liver

○Yuki Obata1,2, Shotaro Uehara2, Yuichiro Higuchi2, Yukari Totsuka1, Hiroshi Suemizu2 (1. Hoshi University, 2. Central Institute for Experimental Medicine and Life Science)
10:06 AM - 10:18 AM JST(1:06 AM - 1:18 AM UTC)

[27-12-am04]Evaluation of atazanavir as a CYP3A5 probe drug

○Genki Minegishi1, Kaoru Kobayashi1 (1. Meiji Pharm. Univ.)
10:18 AM - 10:30 AM JST(1:18 AM - 1:30 AM UTC)

[27-12-am05]Contribution of blood cell-binding quercetin to in vivo antioxidant effect and rapid disposition

○Yukari Ueda1, Tadatoshi Tanino1 (1. Tokushima Bunri Univ. Laboratory of Pharmaceutics)
10:30 AM - 10:42 AM JST(1:30 AM - 1:42 AM UTC)

[27-12-am06S]Semi-Mechanistic Modeling of Indocyanine Green Disposition Informed by Plasma and Biliary Excretion Profiles

○Wei-Chun Wang1, Wan-Tien Wu1, Yu-Chieh Lin1, Ching-Ling Cheng1, Chen-Hsi Chou1 (1. Institute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung University, TAIWAN)
10:42 AM - 10:54 AM JST(1:42 AM - 1:54 AM UTC)

[27-12-am07S]Impact of Blood Concentration–Equivalent Therapeutic Drug Exposure on P-gp and Drug Resistance in Follicular Lymphoma Cells

○Moka Komatsu1, Yumiko Iwase1, Takuo Ogihara2, Kentaro Yano1 (1. Yokohama University of Pharmacy, 2. Tokyo University of Science)
10:54 AM - 11:06 AM JST(1:54 AM - 2:06 AM UTC)

[27-12-am08S]Elucidation of the mechanism of prostaglandin E2 clearance in the liver and suppression of acute liver injury by its regulation

○Yusuke Yabuuchi1, Hiroaki Shimada1,2, Atsushi Kawase1,2, Fuminori Sakurai1,2 (1. Grad. Sch. Pharm. Sci., Kindai Univ., 2. Fac. Pharm, Kindai Univ.)
11:06 AM - 11:18 AM JST(2:06 AM - 2:18 AM UTC)

[27-12-am09]Construction of a physiologically based pharmacokinetic model of vildagliptin that can describe DPP-4 inhibition as a pharmacodynamic index

○Masahiro Kakizaki1, Ryo Nakamura1,2, Yukana Tomoda1, Takashi Yoshikado1, Satofumi Iida1, Mikako Oka1, Koji Chiba1 (1. Yokohama University of Pharmacy, 2. A2 Healthcare)
11:18 AM - 11:30 AM JST(2:18 AM - 2:30 AM UTC)

[27-12-am10S]Investigation of the alteration and regulation of hepatic drug-metabolizing enzymes by the oncolytic virus reovirus

○Shoya Oue1, Atsushi Kawase1, Yanqin Dou1, Hiroaki Shimada1, Ken J Ishii3, Fuminori Sakurai1,2 (1. Fac. Pharm. Kindai Univ, 2. Grad. Sch. Pharm. Osaka Univ, 3. Ins. Med Sci, Tokyo Univ)
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