The 146th Annual Meeting of the Pharmaceutical Society of Japan (Osaka)
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Session Details

Oral Presentation(E) Pharmaceutical Health Care and Sciences

[27-13-am]Pharmaceutics 4, ADME/PK-PD/Drug interaction

Fri. Mar 27, 2026 9:30 AM - 11:30 AM JST
Fri. Mar 27, 2026 12:30 AM - 2:30 AM UTC
Room 13 (C404, Bldg. 2, Area 2 [4F])
Chair: Yukio Kato, Hamamura Kengo
9:30 AM - 9:42 AM JST(12:30 AM - 12:42 AM UTC)

[27-13-am01S]Comparative analysis of pharmacokinetics of the HIF-PH inhibitor roxadustat and the OATP1B substrate indocyanine green in rats.

○Kazune Sano1, Yumiko Takebayashi1, Hideyuki Motohashi1, Junya Nagai1 (1. Grad. Sch. Pharm. Sci., Osaka Medical and Pharmaceutical Univ.)
9:42 AM - 9:54 AM JST(12:42 AM - 12:54 AM UTC)

[27-13-am02S]Risk of serotonin syndrome during combined opioid analgesic use

○Takuto Tanaka1, Ryuuichiro Hosoya1,2, Tomoko Terajima1, Kokubun Hideya1, Yoshihiro Uezawa2, Hajime Kagaya1 (1. Sch.Pharm.Sci.,Shonan University of M edical Sciences, 2. Sch.Pharm.Sci.,Meiji Pharmaceutical University)
9:54 AM - 10:06 AM JST(12:54 AM - 1:06 AM UTC)

[27-13-am03S]Anti-PEG IgG, not anti-PEG IgM, causes Doxil-induced anaphylaxis
in mice

○Shuto Yamaguchi1, Haruka Takata1,2, Shingo Kobayashi1,2, Hidenori Ando1,2, Tatsuhiro Ishida1,2 (1. Inst. of Biomed. Sci., Tokushima Univ., 2. Innovative Res. Ctr. for DDS, Inst. of Biomed. Sci., Tokushima Univ.)
10:06 AM - 10:18 AM JST(1:06 AM - 1:18 AM UTC)

[27-13-am04S]Development and application of LC-MS/MS for simultaneous determination of three sedatives and a metabolite in rat plasma

○Rina Kakuba1, Yuhki Sato1, Yuka Nagatsuka1, Takuya Abe2, Yutaka Fujii2 (1. Fac. Pharm.Pharmacecut.Sci., Fukuyama Univ., 2. Department of Medical Technology, Niigata University of Health and Welfare.)
10:18 AM - 10:30 AM JST(1:18 AM - 1:30 AM UTC)

[27-13-am05S]Influence of ferroptosis on the inhibitory effect of reduced vitamin K against rotenone-induced cell death

○Katsuto Nakao1, Masako Harada1, Shotaro Goto1, Shuichi Setoguchi1, Kazuhisa Matsunaga1 (1. Pharm. Sci., Fukuoka Univ.,)
10:30 AM - 10:42 AM JST(1:30 AM - 1:42 AM UTC)

[27-13-am06S]Quantification of co-amorphous in the tablets by Raman spectroscopy with Artificial Neural Network analysis

○Maria Osanai1, Tatsuo Koide2, Ayano Takii1, Keiji Hirota1, Toshiro Fukami 1 (1. Meiji Pharmaceutical Univ., 2. National Institute of Health Sciences.)
10:42 AM - 10:54 AM JST(1:42 AM - 1:54 AM UTC)

[27-13-am07]Investigation of methods for evaluating the effects of sterilization on the substrate material of microneedle arrays

○Hideyuki Sakoda1, Toshihiro Hosen2, Yusuke Tsuboko1, Eiichi Yamamoto1, Daisuke Ando1 (1. National Institute of Health Sciences, 2. RHESCA CO., LTD.)
10:54 AM - 11:06 AM JST(1:54 AM - 2:06 AM UTC)

[27-13-am08]End-to-End automated dissolution testing enabling liquid chromatography analysis: Implementation of a fully automated dissolution system

○KENTO MAEJIMA1, Tamaki Gion1, Ayami Kazama1, Nozomi Ogawa1, Masatoshi Karashima1, Craig Kaftan1 (1. Takeda Pharmaceutical Company Ltd.)
11:06 AM - 11:18 AM JST(2:06 AM - 2:18 AM UTC)

[27-13-am09S]Enhancing monoclonal antibody stability using Trimethylamine-N-oxide (TMAO)

○Miftahus Saadah1, Veysel Kayser1 (1. Sydney Pharmacy School, The University of Sydney, Australia)
11:18 AM - 11:30 AM JST(2:18 AM - 2:30 AM UTC)

[27-13-am10S]Stabilization mechanism for adeno-associated viral vectors lyophilized with excipients and their storage stability

○Motoki Sugiura1, Tomoyuki Okuda1, Hirokazu Okamoto1 (1. Grad. Sch. Pharm. Sci., Meijo Univ.)
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