[27-14-am] Science for Drug Formulation 4, Controlled release/Targeting | The 146th Annual Meeting of the Pharmaceutical Society of Japan (Osaka)

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Oral Presentation(E) Pharmaceutical Health Care and Sciences

[27-14-am]Science for Drug Formulation 4, Controlled release/Targeting

Fri. Mar 27, 2026 9:30 AM - 11:30 AM JST
Fri. Mar 27, 2026 12:30 AM - 2:30 AM UTC

Room 14 (C507, Bldg. 2, Area 2 [5F])

Chair: Kazunori Iwanaga, Hisanao Kishimoto

9:30 AM - 9:42 AM JST(12:30 AM - 12:42 AM UTC)

[27-14-am01S]"Stabilization of pH-responsive self-destructive liposomes by Tween 60 and DHSM"

○Sae Akaki¹, Yusuke Kono¹, Hiroyasu Takemoto², Makoto Oba², Masaki Morishita¹, Ken-ichi Ogawara¹ (1. Kobe Pharm Univ., 2. Grad. Sch. Med. Sci., Kyoto Pref Univ. Med.)

9:42 AM - 9:54 AM JST(12:42 AM - 12:54 AM UTC)

[27-14-am02S]Development of formulations with enhanced tumor selectivity and retention for boron neutron capture therapy

○Shota Tanaka¹, Konoka Baba², Kodai Yamashita², Aoi Fujimaki², Nodoka Aoki², Itsuki Fukuda¹, Daiki Tokura¹, Kakeru Konarita¹, Kensuke Suzuki³, Minoru Suzuki⁴, Takashi Temma^4,5, Takahiro Nomoto^1,2 (1. Grad. Sch. Arts Sci., UTokyo, 2. Coll. Arts Sci., UTokyo, 3. Stella Pharma, 4. Inst. for Integr. Radiat. Nucl. Sci., Kyoto Univ., 5. Fac. Pharm., Osaka Med. Pharm. Univ.)

9:54 AM - 10:06 AM JST(12:54 AM - 1:06 AM UTC)

[27-14-am03S]Optimized loading of nucleic acids into hippocampal neuron-targeted extracellular vesicles and their gene silencing effects.

○Mana Yamada¹, Hikari Ama², Susumu Suwabe², Mariko Takeda-Morishita^1,2, Noriyasu Kamei ^1,2 (1. Grad. Sch. Pharm. Sci., Kobe Gakuin Univ., 2. Fac. Pharm. Sci., Kobe Gakuin Univ.)

10:06 AM - 10:18 AM JST(1:06 AM - 1:18 AM UTC)

[27-14-am04S]Design and evaluation of seasonal influenza vaccine using needle-free intraepidermal administration device

○Masahiro Ogura¹, Riru Onigahara¹, Toru Taharabaru¹, Taishi Higashi^1,2, Shogo Misumi^1,2, Naoki Kishimoto^1,2, Hirotoshi Adachi³, Masahiko Kikuchi^2,4, Keiichi Motoyama^1,2 (1. Grad. Sch. Pharm. Sci., Kumamoto Univ., 2. VDRC, 3. PassPort Technologies, Inc, 4. UTOPIA)

10:18 AM - 10:30 AM JST(1:18 AM - 1:30 AM UTC)

[27-14-am05S]Generalizing the development of protein-encapsulated nanoparticles using functional lipids

○Tatyuya Kobayashi¹, Hiroyuki Koide¹, Midori Watanabe¹, Kenji Yamashita¹, Yoshitaka Hamashima¹, Takehisa Dewa², Asai Tomohiro¹ (1. Grad. Sch. Pharm. Sci.,Univ.of Shizuoka, 2. Grad. Sch. Eng.,Univ.of Nagoya Institute of Technology)

10:30 AM - 10:42 AM JST(1:30 AM - 1:42 AM UTC)

[27-14-am06S]In vivo targeting of renal fibrotic tissue with an amine-terminated PEG-modified liposomes

○Yuka Kano¹, Haruka Takata^1,2, Hitoshi Matsumoto¹, Ayano Aihara¹, Shingo Kobayashi^1,2, Hidenori Andou^1,2, Tatsuhiro Ishida^1,2 (1. Inst. of Biomed. Sci., Tokushima Univ., 2. Innovative Res. Ctr. for DDS, Inst. of Biomed. Sci., Tokushima Univ.)

10:42 AM - 10:54 AM JST(1:42 AM - 1:54 AM UTC)

[27-14-am07]Intracellular Localization Analysis of Nanoparticle Formulations by Cryo-Electron Microscopy

○Miya Urui¹, Kenichi Yoshihara¹, Ryosuke Yoshioka², Shinichi Hata³, Nobutaka Numoto⁴, Pi-Cheng Tsai⁴, Yuya Tsurudome², Kentaro Ushijima², Jian-Ren Shen⁴, Michiko Horiguchi¹ (1. Grad. Sch. Pharm. Sci. Okayama Univ., 2. Pharm. Sci. Sanyo-Onoda City Univ., 3. Eng. Sanyo-Onoda City Univ., 4. RIIS Okayama Univ.)

10:54 AM - 11:06 AM JST(1:54 AM - 2:06 AM UTC)

[27-14-am08]Effects of lipid composition on pulmonary pharmacokinetics/toxicity of inhaled dry powder formulations for nanoparticle self-assembly

○Tomoyuki Okuda¹, Yudai Kajiyama¹, Hirokazu Okamoto¹ (1. Fac. Pharm., Meijo Univ.)

11:06 AM - 11:18 AM JST(2:06 AM - 2:18 AM UTC)

[27-14-am09]Retro-Inverso Bradykinin–Conjugated Polymers Enhance Tumor Accumulation of Nanomedicines

○Mamoru Haratake¹, Anthony Assumang¹, Hideaki Nakamura¹, Masaya Morimitsu¹ (1. Sojo University)

11:18 AM - 11:30 AM JST(2:18 AM - 2:30 AM UTC)

[27-14-am10S]Spleen immunization with cellular membrane protein-bearing PEGylated liposomes successfully induces production of anti-membrane protein antibodies

○Takanori Higashi¹, Hidenori Ando^1,2, Shunto Yamamoto¹, Haruki Tanaka¹, Haruka Takata^1,2, Shingo Kobayashi^1,2, Tatsuhiro Ishida^1,2 (1. Inst. of Biomed. Sci., Tokushima Univ., 2. Innovative Res. Ctr. for DDS, Inst. of Biomed. Sci., Tokushima Univ.)

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