The 146th Annual Meeting of the Pharmaceutical Society of Japan (Osaka)
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Session Details

Oral Presentation(E) Pharmaceutical Health Care and Sciences

[27-21-pm]Science for Drug Formulation 5, Drug delivery system in therapy

Fri. Mar 27, 2026 1:10 PM - 3:10 PM JST
Fri. Mar 27, 2026 4:10 AM - 6:10 AM UTC
Room 21 (D401, Bldg. 4, Area 3 [4F])
Chair: Hidetaka Akita, Takayuki Oguma
1:10 PM - 1:22 PM JST(4:10 AM - 4:22 AM UTC)

[27-21-pm01S]Development of pH-responsive polybetaines and their application to solid tumor treatment using lipid nanoparticles

○Motoaki Kobayashi1,2, Koki Yanagida2, Wanphiwat Chintrakulchai1,2, Kaede Nikaido1,2, Sora Miyashita2, Takada Fumito3, Taiki Morita3, Koichi Ogi3, Junya Michinishi3, Tomoyuki Ohtake3, Kyohei Muguruma1,2, Yuto Honda1,2,4, Hiroyasu Takemoto5, Yutaka Miura1,2, Nobuhiro Nishiyama1,2,4 (1. Sch. of Life Sci. and Tech., Science Tokyo, 2. Lab. for Chem. and Life Sci., Science Tokyo, 3. NOF, 4. iCONM, 5. Grad. Sch. Med. Sci., Kyoto Prefecture Univ. of Medicine)
1:22 PM - 1:34 PM JST(4:22 AM - 4:34 AM UTC)

[27-21-pm02]The new roles of Pt(IV) prodrug for metal-organic framework-based anticancer nanomedicines

○Teng-Hao Chen1 (1. Sch. Pharm., National Cheng Kung Univ.)
1:34 PM - 1:46 PM JST(4:34 AM - 4:46 AM UTC)

[27-21-pm03S]Enzyme delivery into the target body tissues by iontophoresis

○Shinya Inoue1, Yusuke Yoshimura1, Shintaro Yoneda2,3, Naoshi Yamazaki2, Kentaro Kogure2,3 (1. Grad. Sch. Pharm. Sci., Tokushima Univ., 2. Grad. Sch. Biomed. Sci., Tokushima Univ., 3. DDS Res. Cent., Tokushima Univ.)
1:46 PM - 1:58 PM JST(4:46 AM - 4:58 AM UTC)

[27-21-pm04]Efficient and Facile Liver-Targeting System Utilizing the Molecular Mobilities of GalNAc-Modified Polyrotaxane

○Toru Taharabaru1, Keiichi Motoyama1, Taishi Higashi1 (1. Graduate School of Pharmaceutical Sciences, Kumamoto University)
1:58 PM - 2:10 PM JST(4:58 AM - 5:10 AM UTC)

[27-21-pm05S]Development of LSR-targeted liposomes modified by a LSR binder, angubindin-1

○Natsuki Uchihashi1, Shizuki Kimura1, Yuki Niwa2, Daiki Omata3, Ryo Suzuki3, Masuo Kondoh2,4,5 (1. Sch. Pharm. Sci., UOsaka, 2. Grad. Sch. Pharm. Sci., UOsaka, 3. Grad. Sch. Pharm. Sci., Teikyo Univ., 4. CiDER, UOsaka, 5. MEI, UOsaka)
2:10 PM - 2:22 PM JST(5:10 AM - 5:22 AM UTC)

[27-21-pm06S]Engineered macrophages (MacTrigger) destroying
immunosuppressive condition of solid tumor and its usefulness

○Airi Nagai1, Teruki Nii2,3, Toma Yoshimi2, Yusuke Hamabe2, Kenta Tanito2, Akihiro Kishimura2,3, Takeshi Mori2,3, Haruka Takata4, Tatsuhiro Ishida4, Yoshiki Katayama2,3 (1. Undergrad. Sch. Engineering., Kyushu Univ., 2. Grad. Sch. Systems Life Sci., Kyushu Univ., 3. Grad. Sch. Engineering., Kyushu Univ., 4. Grad. Sch. Biomedical Sci (Pharm)., Tokushima Univ.)
2:22 PM - 2:34 PM JST(5:22 AM - 5:34 AM UTC)

[27-21-pm07S]Characterization of mitochondrial quality and functional evaluation in neurons of microglia- and mesenchymal stromal cell-derived mitochondria

○Nao Tsubata1, Mao Yoshihara2, Kosuke Kusamori2, Yasuhiro Kosuge3, Takanori Kanazawa1,4,5 (1. Sch. Pharm. Sci., Tokushima Univ., 2. Fac. Pharm. Sci., Tokyo Univ. Sci., 3. Sch. Pharm, Nihon Univ., 4. Grad. Sch. Biomed. Sci., Tokushima Univ., 5. Inno. Res. Cent. DDS., Tokushima Univ.)
2:34 PM - 2:46 PM JST(5:34 AM - 5:46 AM UTC)

[27-21-pm08S]Antioxidant and cytoprotective effects of hempseed-derived nanoparticles in a skin photoaging model

○Katsuhisa Gono1, Shouko Itakura1,2, Kousuke Kusamori1,2, Makiya Nishikawa1,2 (1. Fac. Pharm. Sci., Tokyo Univ. Sci., 2. Res. Inst. Sci. Technol., Tokyo Univ. Sci.)
2:46 PM - 2:58 PM JST(5:46 AM - 5:58 AM UTC)

[27-21-pm09S]Regulation of the cellular uptake and in vivo pharmacokinetics of antisense oligonucleotides via protein binding

○Koutarou Ishii1, Shoko Itakura1,2, Kosuke Kusamori1,2, Syunsuke Yamamoto3, Sinji Iwasaki3, Hiroyuki Kusuhara4, Takanori Yokota2, Hideki Hirabayashi3, Makiya Nishikawa1,2 (1. Fac. Pharm. Sci., Tokyo Univ. Sci., 2. Res. Inst. Sci. Technol., Tokyo Univ. Sci., 3. Takeda Pharmaceutical Co., Ltd., 4. Grad. Sch. Pharm. Sci., Univ. Tokyo.)
2:58 PM - 3:10 PM JST(5:58 AM - 6:10 AM UTC)

[27-21-pm10S]Development of ASO/LNP formulations targeting TP53 intron retention

○Katsunori SAITO1, Akihide YOSHIMI2, Tomohiro ASAI1 (1. Grad. Sch. Parm. Sci., Univ. of Shizuoka., 2. National Cancer Center Japan)
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