[27-23-pm] Synthesis (incl. Total synthesis) 3/Chemical reaction development, mechanistic analysis, computational chemistry 1 | The 146th Annual Meeting of the Pharmaceutical Society of Japan (Osaka)

The 146th Annual Meeting of the Pharmaceutical Society of Japan (Osaka)

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Oral Presentation(A) Pharmaceutical Chemistry

[27-23-pm]Synthesis (incl. Total synthesis) 3/Chemical reaction development, mechanistic analysis, computational chemistry 1

Fri. Mar 27, 2026 1:10 PM - 2:58 PM JST
Fri. Mar 27, 2026 4:10 AM - 5:58 AM UTC

Room 23 (2105)

Chair: Masanori Nagatomo, Fumihiko Yoshimura

1:10 PM - 1:22 PM JST(4:10 AM - 4:22 AM UTC)

[27-23-pm01S]Synthetic study of pyrroloiminoquinones targeting makaluvamine alkaloids

○Yo Kiichi¹, Rin Matsubayashi², Anna Kitano², Yuiko Yasuda², Kazuki Noguchi², Naoyuki Kotoku^1,2 (1. Grad. Sch. Pharm. Sci., Ritsumeikan Univ., 2. Coll. Pharm. Sci., Ritsumeikan Univ.)

1:22 PM - 1:34 PM JST(4:22 AM - 4:34 AM UTC)

[27-23-pm02S]Synthetic study of macrophilones

○Rin Matsubayashi¹, Yo Kiichi¹, Naoyuki Kotoku¹ (1. Coll. Pharm. Sci., Ritsumeikan Univ.)

1:34 PM - 1:46 PM JST(4:34 AM - 4:46 AM UTC)

[27-23-pm03S]Synthetic Study of Ansamycin Natural Product Cytotrienin A

○Aina Nobukuni¹, Chisato Mori¹, Jun Sakata¹, Shinpei Sato², Keita Komine¹, Hayato Fukuda¹, Mizuki Watanabe², Satoshi Shuto², Jun Ishihara¹ (1. Grad. Sch. Biomed. Sci., Nagasaki Univ., 2. Fac. Pharm. Sci., Hokkaido Univ.)

1:46 PM - 1:58 PM JST(4:46 AM - 4:58 AM UTC)

[27-23-pm04S]Synthetic Studies on Lyconesidine A based on Three Component Radical Coupling

○Ryota Oki¹, Yuta Yamazaki¹, Keita Komine¹, Hayato Fukuda¹, Jun Ishihara¹ (1. Grad. Sch. Biomed. Sci., Nagasaki Univ.)

1:58 PM - 2:10 PM JST(4:58 AM - 5:10 AM UTC)

[27-23-pm05S]A Convenient Synthesis of Triarylantimony Difluorides (Ar₃SbF₂)

○Zihao Zhong¹, Kouki Narita¹, Mio Matsumura², Shuji Yasuike², Masayuki Kirihara¹ (1. Department of Materials & Life Science, Shizuoka Inst. Sci. Tech, 2. School of Pharm. Sci. Aichi Gakuin Univ.)

2:10 PM - 2:22 PM JST(5:10 AM - 5:22 AM UTC)

[27-23-pm06S]Synthesis of oligonucleotides containing syn-constrained 2'-deoxyguanosine

○Kotomi Fukumoto¹, Yuta Ito¹, Yasufumi Fuchi¹, Yoshiyuki Hari¹ (1. Fac. Pharm. Sci., Tokushima Bunri Univ.)

2:22 PM - 2:34 PM JST(5:22 AM - 5:34 AM UTC)

[27-23-pm07S]Synthesis and evaluation of a novel universal linker for oligonucleotide synthesis

○Kotone Kuwahara¹, Yasufumi Fuchi¹, Yuta Ito¹, Yoshiyuki Hari¹ (1. Fac. Pharm. Sci., Tokushima Bunri Univ.)

2:34 PM - 2:46 PM JST(5:34 AM - 5:46 AM UTC)

[27-23-pm08]Computer-assisted design and development of novel (aza)quinone methide-based small-molecule anticancer prodrugs

○Sascha Georg Keller¹, Kento Hayashi, Ryo Tachibana¹, Kyohhei Fujita¹, Mako Kamiya², Yasuteru Urano¹ (1. The University of Tokyo, 2. Institute of Science Tokyo)

2:46 PM - 2:58 PM JST(5:46 AM - 5:58 AM UTC)

[27-23-pm09]Construction of tricyclic indoline scaffolds via Ni-catalyzed asymmetric propargylic substitution

○Kenichi Michigami¹, Fuga Kishida¹, Mitsuhiro Ueda¹, Masato Ohashi¹ (1. Grad. Sch. Sci., OMU)

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