The 146th Annual Meeting of the Pharmaceutical Society of Japan (Osaka)
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Session Details

Oral Presentation(A) Pharmaceutical Chemistry

[27-29-pm]Screening

Fri. Mar 27, 2026 3:30 PM - 5:30 PM JST
Fri. Mar 27, 2026 6:30 AM - 8:30 AM UTC
Room 29 (3401)
Chair: Hiroaki Itoh, Kazuki Yamamoto
3:30 PM - 3:42 PM JST(6:30 AM - 6:42 AM UTC)

[27-29-pm11S]Evaluation of the membrane permeability of cyclic peptides using DNA-encoded library technology

○Seichi Agehara1, Yuki Aketa1, Jumpei Morimoto1, Shinsuke Sando1 (1. Grad. Sch. Eng., Tokyo Univ.)
3:42 PM - 3:54 PM JST(6:42 AM - 6:54 AM UTC)

[27-29-pm12S]Identification of small molecule ligands for the growth hormone secretagogue receptor type 1a

○Sakura Okada1, Yukihiro Itoh1,2, Yuki Shiimura3,4, Dohyun Im4, Takayoshi Suzuki1 (1. Grad. Sch. Sci., The Univ. of Osaka, 2. LBB, Inst. of Integrated Res., Inst. of Sci. Tokyo, 3. Div. of Mol. Genet., Inst. of Life Sci., Kurume Univ., 4. Dept. of Cell Biol., Grad. Sch. of Med., Kyoto Univ.)
3:54 PM - 4:06 PM JST(6:54 AM - 7:06 AM UTC)

[27-29-pm13]Search for microglial activation inhibitors – Utilization of the meroterpenoid library constructed by synthetic biology

○Kanako TAKAHASHI1, Zhiyang Quan2, Yukari Shigemoto-Mogami1, Bei-bei Zhang3, Tomohiko Ohwada4, Ikuro Abe3, Takayoshi Awakawa2, Kaoru Sato1 (1. Lab. Neuropharmacol., Div. Pharmacol., Nat. Inst. Hlth. Sci., 2. RIKEN Center for Sustainable Resource Science, 3. Lab. Natural Products Chemistry, Grad. Sch. Pharma. Sci., Tokyo Univ., 4. Lab. Organic and Medicinal Chemistry, Grad. Sch. Pharma. Sci., Tokyo Univ)
4:06 PM - 4:18 PM JST(7:06 AM - 7:18 AM UTC)

[27-29-pm14S]Efficient Discovery and Validation of Novel AKR1B10 Inhibitors using the Co-folding Structural Prediction Model Boltz-2

○shinya kawano1,2, akira ilkari1, satoshi endo3,4,5, kentaro tomii2 (1. Grad. Sch. Pharm. Sci., Gifu Pharm. Univ., 2. AIRC, AIST, 3. UGS-DDMIS, Gifu Univ., 4. COMIT, Gifu Univ., 5. PFRC, Gifu Univ.)
4:18 PM - 4:30 PM JST(7:18 AM - 7:30 AM UTC)

[27-29-pm15S]Development of a Comprehensive GPCR Screening System for Ligand Deorphanization

○Aoi Matsushita1, Kouki Kawakami2, Ayami Fukunaga1, Hideaki E. Kato1,2 (1. Grad. Sch. Sci., UTokyo, 2. RCAST, UTokyo)
4:30 PM - 4:42 PM JST(7:30 AM - 7:42 AM UTC)

[27-29-pm16]Affinity/Reactivity-based Co-selection of Covalent DNA Aptamers (ARCaDia)

○Masumi Taki1 (1. The University of Electro-Communications (UEC))
4:42 PM - 4:54 PM JST(7:42 AM - 7:54 AM UTC)

[27-29-pm17S]Discovery of PROTACs with 'artificial natural products'

○Yuki Nakamura1, Mai Yoshimi1, Shun Saito1, Midori A. Arai1 (1. Grad. Sch. Sci. Tec., Keio Univ.)
4:54 PM - 5:06 PM JST(7:54 AM - 8:06 AM UTC)

[27-29-pm18S]Selective cytotoxicity of marine-derived fungal extracts against glucose-starved PANC-1 cells

○Zenith Putri Dewianti1,2, Muhammad Azhari1, Elfahmi Elfahmi3, Sophi Damayanti1, Masayoshi Arai4, Elin Julianti1 (1. Dept. Pharm. Chem., Sch. Pharm., ITB., 2. Dept. Pharm. Chem. Sci., Fac. Pharm., UNIMAR., 3. Dept. of Pharm. Biol., Sch. Pharm., ITB., 4. Lab. Nat. Prod. Drug Discov., Grad. Sch. Pharm. Sci., Osaka Univ.)
5:06 PM - 5:18 PM JST(8:06 AM - 8:18 AM UTC)

[27-29-pm19S]Discovery of Cancer Stem-Like Cell–Selective Inhibitors using Existing Drug Library

○Shiori Yanai1, Shoki Fujita1, Toshiki Ohtomo2, Kao Suzuki1, Satoko Otsuguro1, Yusuke Ohta1, Itsuki Kageyama2, Masahito Ohue3, Kota Kodama2, Takao Nomura1, Katsumi Maenaka1,4 (1. Grad. Sch. Pharm. Sci., Hokkaido Univ., 2. Grad. Sch. Pharm. Sci., Hoshi Univ., 3. Sch. Computing, Inst. Sci. Tokyo, 4. Grad. Sch. Pharm. Sci., Kyushu Univ.)
5:18 PM - 5:30 PM JST(8:18 AM - 8:30 AM UTC)

[27-29-pm20S]Bioactive Compound Identification Utilizing Molecular Dynamics Simulation

○Kakeru Nagaura1, Tomoyuki Miyao1,2 (1. Grad. Sch. Sci. Tech., NAIST, 2. DSC, NAIST)
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