The 146th Annual Meeting of the Pharmaceutical Society of Japan (Osaka)
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Session Details

Oral Presentation(C) Pharmaceutical Biology

[28-26-am]Biology of Organ Systems/Evaluation of drug efficacy and safety

Sat. Mar 28, 2026 9:30 AM - 11:30 AM JST
Sat. Mar 28, 2026 12:30 AM - 2:30 AM UTC
Room 26 (2501, Bldg. 2, Area 4 [5F])
Chair: Satoshi Akiba, Takashi Sato
9:30 AM - 9:42 AM JST(12:30 AM - 12:42 AM UTC)

[28-26-am01S]Cardiomyocyte-specific SETD3KO suppressed the progression of heart failure and cardiomyocyte hypertrophy

○Yuto Suzuki1,2, Yoichi Sunagawa1,2,3, Ryuji Minegishi1, Haname Sekido1, Yasuhumi Katanasaka1,2,3, Koji Hasegawa1,2, Tatsuya Morimoto1,2,3,4, Tetsuya Hosooka1 (1. Division of Molecular Medicine, Grad. Sch. Pharm. Sci. University of Shizuoka, 2. Division of Translational Research, Clinical Research Institute, Kyoto Medical Center, NHO., 3. Shizuoka General Hospital., 4. Department of Pharmacology, Sch. Med., Toho Univ.)
9:42 AM - 9:54 AM JST(12:42 AM - 12:54 AM UTC)

[28-26-am02S]Possibility of Miglustat as treatment for Systemic Sclerosis

○Takuro Tomitsuka1, Fuka Tukiyama1, Miaki Uzu1, Hiroyuki Nakamura1 (1. Grad. Sch. Pharm. Sci.,Chiba Univ.)
9:54 AM - 10:06 AM JST(12:54 AM - 1:06 AM UTC)

[28-26-am03S]Role of mitochondrial DHODH in placental trophoblast invasion

○Tomoka Shimooki1, Kazuya Kusama1, Kanoko Yoshida1, Atsuya Tsuru1, Mikihiro Yoshie1, Kazuhiro Tamura1 (1. Tokyo Univ. Pharm. & Life Sci.)
10:06 AM - 10:18 AM JST(1:06 AM - 1:18 AM UTC)

[28-26-am04]Therapeutic effect of D-cysteine against cell and mouse models of metabolic dysfunction-associated steatotic liver disease

○Takahiro Seki1,2, Kento Nasu2, Hitoshi Maeda3, Natsuko Hitora-Imamura2, Yuki Kurauchi2, Ayumu Konno4, Hirokazu Hirai4, Hiroshi Watanabe5, Toru Maruyama6, Hiroshi Katsuki2 (1. Dept. Pharmacol., Fac. Pharm. Sci, Himeji Dokkyo University, 2. Dept. Chemico-Pharmacol. Sci., Grad. Sch. Pharm. Sci., Kumamoto Univ., 3. Dept. Biopharmaceutics., Kyoto Pharm. Univ. , 4. Dept. Neurophysiol. Neural Repair, Gunma Univ. Grad. Sch. Med., 5. Dept. Clin. Pharm. Ther., Grad. Sch. Pharm. Sci., Kumamoto Univ., 6. Dept. Biopharmaceutics., Grad. Sch. Pharm. Sci., Kumamoto Univ.)
10:18 AM - 10:30 AM JST(1:18 AM - 1:30 AM UTC)

[28-26-am05S]Mechanistic insights into iron-mediated progression of chronic cholestatic liver disease

○Yudai Ohta1, Toshiro Moroishi2 (1. Dept. of Mol. Pharmacol., Grad. Sch. of Life. Sci., Kumamoto Univ., 2. Div. of Cellular Dynamics, MRI, Inst. of Science Tokyo)
10:30 AM - 10:42 AM JST(1:30 AM - 1:42 AM UTC)

[28-26-am06S]Sex difference analysis of drug-induced arrhythmias regulated by sex hormones using a dizygotic twin iPS cell model

○Masashi Wakabayashi1, Akihito Ota1, Keisuke Ando1, Satoshi Shimizu1, Kazuho Sakamoto1,2, Masami Kodama1, Yoichi Sunagawa3, Yasunari Kanda4, Tatsuya Morimoto3,5, Junko Kurokawa1 (1. Dept. Bio-inform. Pharmacol., Univ. of Shizuoka, Shizuoka, Japan, 2. Dept. Pharm. Sci., Int. Univ. Health Welfare, Tochigi, Japan, 3. Div. Mol. Med., Univ. of Shizuoka, Shizuoka, Japan, 4. Div. Pharmacol., NIHS, Kanagawa, Japan, 5. Dept. Pharmacol., Toho Univ, Tokyo, Japan)
10:42 AM - 10:54 AM JST(1:42 AM - 1:54 AM UTC)

[28-26-am07S]Spatiotemporal Analysis of ZIP10-Expressing Cells using Primary and Organoid Hair Follicles Culture Systems

○Kento Chayabana1, Takafumi Hara1, Hatsuna Miyake1, Nobuyuki Shiuchi1, Misato Kikuchi1, Emi Yoshigai2,1, Toshiyuki Fukada1 (1. Fac. Pharm Sci., Tokushima Bunri Univ., 2. Fac. Med., University of Occupational and Environmental Health.)
10:54 AM - 11:06 AM JST(1:54 AM - 2:06 AM UTC)

[28-26-am08]Suppression of pathological retinal angiogenesis following eye drop administration of axitinib nanosuspension

○Saori Deguchi1, Akane Morita1, Toshihide Kashihara1, Hiroko Otake2, Noriaki Nagai2, Tsutomu Nakahara1 (1. Kitasato Univ. Sch. Pharm. Sci., 2. Faculty of Pharm., Kindai Univ.)
11:06 AM - 11:18 AM JST(2:06 AM - 2:18 AM UTC)

[28-26-am09]Molecular network pathway activities of eukaryotic initiation factor 2 (EIF2) signaling and coronavirus pathogenesis

○Shihori Tanabe1, Sabina Quader2, Ryuichi Ono1, Ed Perkins3, Hiroyoshi Tanaka4, Horacio Cabral5 (1. Natl. Inst. Health Sci., 2. iCONM, 3. US Army Engineer R&D Ctr., USA, 4. Grad. Sch. Med. Dent. Pharm. Sci., Okayama Univ, 5. Fac. Engineer., Univ. Tokyo)
11:18 AM - 11:30 AM JST(2:18 AM - 2:30 AM UTC)

[28-26-am10]Inhibitory effects of lansoprazole and omeprazole on CYP2C19-mediated EET production

○Risa Kobayashi1,2, Keita Shibata1,2, Daichi Hayakawa1, Yuki Nishimura2,3, Ayako Watanabe1, Kenji Momo1, Hiroaki Gouda1, Koji Nobe1,2 (1. Grad. Sch. Pharm., Showa Med. Univ., 2. Pharmacol. Res. Ctr., Showa Med. Univ., 3. Grad. Sch. Med., Showa Med. Univ.)
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