The 146th Annual Meeting of the Pharmaceutical Society of Japan (Osaka)
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Session Details

Graduate and Undergraduate Student Symposium

[GS05☆]It's All About Degradation! Young Researchers' Interdisciplinary Challenge Toward Next-Generation Targeted Protein Degraders

Sun. Mar 29, 2026 1:10 PM - 3:10 PM JST
Sun. Mar 29, 2026 4:10 AM - 6:10 AM UTC
Room 09 (B401)
Organizer: Hinata Osawa (Grad. Sch. Med. Dent. Pharm. Sci., Okayama Univ.), Yoshino Akizuki (Grad. Sch. Pharmaceut. Sci., Hoshi Univ.)
1:10 PM - 1:14 PM JST(4:10 AM - 4:14 AM UTC)

挨拶・趣旨説明
大澤 陽（岡山大院医歯薬），秋月 慶乃（星薬大院薬）

1:14 PM - 1:33 PM JST(4:14 AM - 4:33 AM UTC)

[GS05-1]Development of degraders targeting prostaglandin d2synthase

○Hinata Osawa1,2, Norihito Shibata2, Kosuke Aritake3, Yosuke Demizu1,2,4 (1. Grad. Sch. Med. Dent. Pharm. Sci., Okayama Univ., 2. NIHS., 3. Daiichi. Univ. Pharm., 4. Grad. Sch. Med. Life Sci., Yokohama City Univ.)
1:33 PM - 1:52 PM JST(4:33 AM - 4:52 AM UTC)

[GS05-2]Development of small-molecule degraders targeting mitochondria-localized proteins and linker structure–activity relationship study

○Sho Nakamura1, Wakana Yamada1, Mayumi Ishii2, Kayoko Kanamitsu2, Shinichi Sato1,3, Shusuke Tomoshige1, Minoru Ishikawa1 (1. Grad. Sch. Life Sci., Tohoku Univ., 2. Grad. Sch. Pharm. Sci., Univ. Tokyo, 3. FRIS, Tohoku Univ.)
1:52 PM - 2:11 PM JST(4:52 AM - 5:11 AM UTC)

[GS05-3]PROTAC-TS: ML-based PROTAC linker design method considering cell membrane permeability

○Yuki Murakami1,2, Shoichi Ishida1, Nobuo Cho1, Hitomi Yuki2, Masateru Ohta3, Teruki Honma2, Yosuke Demizu1,4, Kei Terayama1,5,6 (1. Grad. Sch. Med. Life Sci., Yokohama City Univ., 2. RIKEN IMS, 3. RIKEN R-CCS, 4. NIHS, 5. RIKEN AIP, 6. Sch. Life Sci. Tech., Science Tokyo)
2:11 PM - 2:30 PM JST(5:11 AM - 5:30 AM UTC)

[GS05-4]Toward Next-Generation AUTACs

○Kazuki Meguro1, Daiki Takahashi1, Hirokazu Arimoto1 (1. Grad. Sch. Life Sci., Tohoku Univ.)
2:30 PM - 2:49 PM JST(5:30 AM - 5:49 AM UTC)

[GS05-5]The mechanism of targeted protein degradation induced by SNIPER(IAP-based PROTAC)

○Sota Hashimoto1, Yoshinori Tsukumo2, Nobumichi Ohoka2, Akinori Endo3, Hinata Osawa2, Yosuke Demizu2, Fumiaki Ohtake4, Yasushi Saeki5, Shigeo Murata1, Mikihiko Naito1 (1. Grad. Sch. of Pharm. Sci., Univ. of Tokyo, 2. NIHS, 3. TMIMS, 4. Hoshi Univ., 5. IMSUT)
2:49 PM - 3:08 PM JST(5:49 AM - 6:08 AM UTC)

[GS05-6]A regulator that enhances the target degradation of cIAP1

○Yoshino Akizuki1,2, Yusuke Sato3, Fumiaki Ohtake1,2 (1. Graduate School of Pharmaceutical Sciences, Hoshi University, 2. Institute for Advanced Life Sciences, Hoshi University, 3. Department of Chemical Biology, Gradraduate School of Engineering, Tottori University)
3:08 PM - 3:10 PM JST(6:08 AM - 6:10 AM UTC)

総括
秋月 慶乃（星薬大院薬）

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