The 146th Annual Meeting of the Pharmaceutical Society of Japan (Osaka)
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Session Details

Poster Presentation(C) Pharmaceutical Biology

[29-63-am]Evaluation of drug efficacy and safety, Chemotherapeutic agents, Kampo medicines, Others 4

Sun. Mar 29, 2026 9:30 AM - 11:30 AM JST
Sun. Mar 29, 2026 12:30 AM - 2:30 AM UTC
Room 63 (4301, Bldg. 4, Area 4 [3F]) (5)
Discusser: Nariko Arimura, Akira Yamashita

[29-63-am-44]Carbazole alkaloids from Clausena harmandiana against PANC-1 human pancreatic cancer cells by targeting PI3K/Akt/mTOR pathway

○Juthamart Maneenet1, Rawiwun Kaewamatawong2, Pornthip Waiwut2, Chantana Boonyarat3, Suresh Awale1 (1. Institute of Natural Medicine, University of Toyama, Japan, 2. Faculty of Pharmaceutical Sciences, Ubon Ratchathani University, Thailand, 3. Faculty of Pharmaceutical Sciences, Khon Kaen University, Thailand)

[29-63-am-45]Analysis of CYP2D6 genotyping and functional characterization of novel variants in a Kenyan population

○Caroline Kijogi1, Eiji Hishinuma2,3, Shota Nishihara1, Akiko Ueda2, Sae Nakajima1, Miki Saito1, Chihiro Kobayashi1, Rei Koyama1, Shinnosuke Matsuoka1, Masamitsu Maekawa1,2,4, Kelvin Musyoka5, Jesse Gitaka6, Wataru Kagaya7, Akira Kaneko8, Yu Miyauchi1,2, Masahiro Hiratsuka 1,2,3,4 (1. Laboratory of Pharmacogenomics, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan, 2. Advanced Research Center for Innovations in Next-Generation Medicine, Tohoku University, Sendai, Japan, 3. Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan, 4. Department of Pharmaceutical Sciences, Tohoku University Hospital, Sendai, Japan, 5. Department of Virology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan, 6. Centre for Malaria Elimination, Mount Kenya University, Thika, Kenya, 7. Department of Eco-epidemiology Institute of Tropical Medicine Nagasaki University, Nagasaki, Japan, 8. Island Malaria Group, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden)

[29-63-am-46]In vitro Anti-glioblastoma Effect and Mechnisms of Chaetoglobosin A, an active compound from Chaetomium globosum Km1226

Shih-Cheng Lin1, Tzong-Huei Lee2, ○Chien-Ju Lin1 (1. School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan, 2. Institute of Fisheries Science, National Taiwan University, Taipei, Taiwan)

[29-63-am-47]Kakkonto effectively reduces body temperature in polyI:C- and LPS-induced fever models.

○Kanako Shinguchi1, Keita Hasegawa1, Nao Muraki1, Keisuke Demachi1, Takanori Kawashima1, Shigeki Chiba1 (1. Kampo Research Labs., Kracie, Ltd.)

[29-63-am-48]Effect of Kikyosekko on Reducing Phlegm Secretion in the Common Cold

○Nao Muraki1, Kaito Suzuki1, Taiga Fujimura1, Nanami Tanikawa1, Takanori Kawashima1, Shigeki Chiba1 (1. Kampo Research Labs. Kracie,Ltd.)

[29-63-am-49]Effects of plant extracts on human dermal fibroblast damage induced by near-infrared irradiation

○Tatsuki Mikane1, Keita Shigeyama1, Ikuyo Sakaguchi1 (1. CLUB COSMETICS CO., LTD.)

[29-63-am-50]Keishibukuryoganryo-ka-Yokuinin Attenuates Delayed Pigmented Spot Formation in UVB-Irradiated Hairless Mice

○Feng Li1, Kanako Shinguchi1, Takanori Kawashima1, Shigeki Chiba1 (1. Kampo Res. Labs., Kracie, Ltd.)

[29-63-am-51]Anticancer Effects of Tetrahydrocurcumin Derivatives on Breast Cancer Cells

○Masako Harada1, Hirofumi Yamakawa3, Shuichi Setoguchi2, Shotaro Goto2, Kazuhisa Matsunaga2 (1. Grad. Sch. Pharm. Sci., Fukuoka Univ., 2. Faculty of Pharm. Sci., Fukuoka Univ., 3. Radioisotope Center, Fukuoka Univ.)

[29-63-am-52]Nonclinical deimmunization strategy of antibody therapeutics

○Chiyomi Kubo1, Keito Ueda1, Eiichi Hashimoto1, Baekjun Pior1, Takaaki Yorimitsu1, Kohei Soga1, Kaori Ito1, Sunsuke Ito1, Jumpei Kiyokawa1, Masaki Honda1 (1. Chugai Pharmaceutical, Co. Ltd.)

[29-63-am-53]Mechanistic analysis of immunogenicity induced by the physicochemical properties of therapeutic antibodies using scRNA-seq

○Keito Ueda1, Tatsuya Ikuno1, Eiichi Hashimoto1, Baekjun Pior1, Takaaki Yorimitsu1, Riku Egami1, Hideaki Mizuno1, Kenta Koyama1, Yuta Narushima1, Nami Yabuki1, Jumpei Kiyokawa1, Masaki Honda1, Chiyomi Kubo1 (1. Chugai Pharmaceutical Co., Ltd.)

[29-63-am-54]Development of an in vitro kidney fibrosis model using three-dimensional cultured human proximal tubule epithelial cell spheroids

○Yukiko Nishioka1, Etsushi Takahashi1, Hayata Maeda1, Kaoru Morimura1, Ayano Araki1, Yoichi Jimbo1 (1. NIKKISO Co., LTD.)
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