講演情報
[20p-P09-5]Soft, transparent, mesh microelectrode mounted on contact lenses for electroretinography monitoring
〇(M2)Qianyu Li1 (1.Waseda Univ.)
キーワード：
electroretinography (ERG)、Multi-Electrode System、soft contact lenses
Electrophysiology measurements, especially electroretinography (ERG), are essential in ophthalmology for diagnosing and treating various ocular diseases. ERG enables the assessment of changes in electric potential generated by retinal neuron cells in response to light stimulation. It serves as a widely used technique for detecting conditions like glaucoma, retinitis pigmentosa, diabetic retinopathy, retinal detachment/splitting, and congenital degenerations.
In this study, we present the development of a soft, transparent multi-electrode system based on commercially available soft contact lenses and its application in measuring ERG responses fromrabbits. The use of commercially available contact lenses as a substrate for this system enables a more conformal and secure interface with the cornea, resulting in higher signal amplitudes in the measured ERG responses compared to rigid contact lens electrodes. The multi-electrodes, actually 7 Au micro-meshes, at different areas of the cornea also allow for the investigation of spatial differences in ERG responses, which can be valuable in the diagnosis and early detection of diseases affecting specific regions of the eye.
In this study, we present the development of a soft, transparent multi-electrode system based on commercially available soft contact lenses and its application in measuring ERG responses fromrabbits. The use of commercially available contact lenses as a substrate for this system enables a more conformal and secure interface with the cornea, resulting in higher signal amplitudes in the measured ERG responses compared to rigid contact lens electrodes. The multi-electrodes, actually 7 Au micro-meshes, at different areas of the cornea also allow for the investigation of spatial differences in ERG responses, which can be valuable in the diagnosis and early detection of diseases affecting specific regions of the eye.