講演情報

[21p-D901-6]Examination of the adhesion tendency of biofilm-forming bacteria on model organic surfaces using quartz crystal microbalance with energy dissipation monitoring

〇(DC)Glenn Villena Latag1, Tomohiro Hayashi1,2 (1.Tokyo TECH, 2.U. Tokyo)

キーワード:

bacterial adhesion、quartz crystal microbalance、biointerface

Bacterial biofilms have a dual nature, providing benefits such as electricity generation and the breakdown of harmful substances. However, they also pose challenges when they form on surfaces like biomedical devices. Understanding the early reversible stage of adhesion is crucial in preventing biofilm formation. In this study, the adhesion tendency of E. coli on different surfaces was analyzed using quartz crystal microbalance with energy dissipation (QCM-D) monitoring. The study identified varying strengths of bacterial attachment on different surfaces, highlighting the attachment manner of bacteria onto protein-adsorbing and resisting surface chemistries. The QCM-D was used as a powerful tool to visualize the bacteria-substrate interface via differences in the penetration depths of the acoustic waves. Our findings provide practical insights for identifying susceptible surfaces and designing strategies to prevent bacterial biofilms on biomedical and industrial devices.