第66回日本神経学会学術大会

Wiesje van der Flier (1975) is full professor and scientific director of Alzheimer Center Amsterdam at Amsterdam UMC, the Netherlands, where she works since 2004. She studied neuropsychology at the University of Utrecht. In addition, she is clinical epidemiologist. She leads the Amsterdam Dementia Cohort, an ongoing memory-clinic based cohort including over 7000 patients with deep phenotyping (MRI, EEG, CSF biomarkers, and PET) and linked biobank (blood, DNA, CSF). The Amsterdam Dementia Cohort is at the basis of many of the studies performed at Alzheimer center Amsterdam. Van der Flier has been (co)promotor of >40 theses and is currently supervising ~10 PhD projects. Van der Fliers main research areas are looking for the origin of AD, diagnosis&prognosis, and intervention&prevention. Van der Flier leads ABOARD (A Personalized Medicine Approach for Alzheimer’s Disease), a Dutch public-private partnership of than 30 partners (www.aboard-project.nl). She is co-initiator of hersenonderzoek.nl, an online platform to link Dutch citizens interested to contribute to brain research to researchers looking for participants.

Dr. Tengfei Guo is an Assistant Professor at the Institute of Neurological and Psychiatric Disorders at Shenzhen Bay Laboratory and Peking University Shenzhen Graduate School. He is primarily devoted to investigating early diagnosis and intervention in Alzheimer’s disease (AD) using multimodal PET and MRI imaging and novel CSF/plasma biomarkers. He initiated the Greater-Bay-Area Healthy Aging Brain Study (GHABS) cohort in 2021, following the standard protocol of the ADNI cohort. More than 1000 older adults have been recruited in GHABS cohort, and completed clinical assessments, fluid biomarkers, MRI imaging, and PET imaging. Based on these data, he has published many research articles in top-tier journals, including Alzheimer’s & Dementia, Molecular Neurodegeneration, Biological Psychiatry, Annals of Neurology, and Neurology as the corresponding author. These contributions have significantly impacted neurodegenerative diseases, particularly in understanding the pathological features, early diagnosis, and clinical trials of AD. He has received funding from the National Science Foundation of China (NSFC) for Excellent Young Scholars, Joint Key Project and General Project, the Guangdong Science Foundation for Distinguished Young Scholars, and the Shenzhen Basic Research Foundation for Excellent Young Scholars.

Atsushi Iwata

Current position
Vice President, Tokyo Metropolitan Institute for Geriatrics and Gerontology

Mar 1993 Graduated with a degree in Medicine, Faculty of Medicine, The University of Tokyo
Mar 2002 Ph.D., University of Tokyo
May 2004 Postdoctoral fellow, Stanford University
Oct 2010 JST "PRESTO" researcher
Apr 2019 Associate Professor, Department of Neurology, Graduate School of Medicine, University of Tokyo
Apr 2020 Director, Department of Neurology, Tokyo Metropolitan Institute for Geriatrics and Gerontology
Oct 2023 Vice President, Tokyo Metropolitan Institute for Geriatrics and Gerontology

Academic positions: Japanese Dementia Society (board member), Japan Neurological Society (Delegate)

Awards: 2012 Japanese Society for Neurology Award (Academic Research Section)

Current interests
Novel drug discovery, cohort studies and novel biomarker development related to dementia.